Ua ʻike anei ʻoe e pili ana i nā kīʻaha koko liʻiliʻi (nā capillaries fenestrated) nona nā 'puka makani' i loko o kou kino?

Ua noʻonoʻo paha ʻoe i ke koʻikoʻi o nā kīʻaha koko liʻiliʻi i loko o ko kākou kino, i kapa ʻia ʻo capillaries? Loaʻa i kekahi mau capillaries nā puka makani liʻiliʻi e like me nā lua i loko. ʻO ia ka mea a mākou e kapa nei he fenestrated capillaries. I kēia lā, e kamaʻilio kākou e pili ana i kēia mau kīʻaha koko kupaianaha, he aha lākou, ma hea lākou, he aha kā lākou hana, a pehea e hiki ai iā mākou ke mālama iā lākou i ke olakino.

He aha kēia mau capillaries i hoʻopaʻa ʻia?

ʻAe, e nānā kākou i ke ʻano o kēia mau capillaries fenestrated. ʻO ka huaʻōlelo Latina 'fenestrae' ʻo ia hoʻi 'puka makani.' No laila, ʻo kēia mau lua liʻiliʻi i loko o kēia mau capillaries, e like me nā puka makani, e ʻae i nā ʻāpana nui a me nā protein, e like me ke koko, e hele i loko o kā mākou mau ʻōpū koʻikoʻi a me nā glands. I ka ʻōlelo maʻalahi, hana lākou e like me kahi ʻōnaehana kānana kūikawā . ʻO lākou kahi e hoʻololi ai ko mākou kino i nā mea a lākou e pono ai a me nā mea ʻaʻole lākou e pono ai.

Aia i hea kēia mau mea i loko o ko kākou kino? He aha kā lākou hana?

I kēia manawa, ke noʻonoʻo nei paha ʻoe, 'Aia i hea kēia mau mea i loko o ko kākou kino? He aha kā lākou hana?' Loaʻa nā capillaries fenestrated i ka nui i loko o ko kākou mau puʻupaʻa , ka ʻōpū liʻiliʻi , ka pancreas, a me nā kelepa endocrine . Pono mau kēia mau ʻōkana e hoʻololi i nā meaʻai a me nā huahana ʻōpala ma waena o nā capillaries a me nā ʻiʻo. ʻO nā pores i loko o kēia mau capillaries e maʻalahi ai kēia hoʻololi.

He aha ke kuleana o kēia mau mea i loko o nā puʻupaʻa?

He mea nui loa nā Capillaries Fenestrated no ko kākou mau puʻupaʻa. Loaʻa i nā puʻupaʻa nā ʻāpana kānana i kapa ʻia he nephrons . E noʻonoʻo wale, aia ma kahi o hoʻokahi miliona o kēia mau nephrons i loko o hoʻokahi puʻupaʻa! ʻAʻole anei he mea kupaianaha? I loko o kēlā me kēia nephron he hui o nā capillaries fenestrated i hōʻuluʻulu ʻia e like me ka pōpō. Ua kapa ʻia kēia ʻo ka glomerulus . ʻO kēia ka mea e hana ana ma ke ʻano he kānana nui .

ʻAʻole wale kēlā, akā aia kekahi mau capillaries ʻē aʻe i hoʻopuni ʻia a puni nā kahawai i loko o nā nephrons. I ka hui pū ʻana, kōkua kēia mau mea i nā puʻupaʻa e kānana i nā huahana ʻōpala mai ke koko, hana i ka mimi, a hoʻopili hou i nā meaʻai e pono ai ke kino. Ua like ia me ke kānana wai i loko o ko mākou hale, akā ʻoi aku ka paʻakikī.

Pehea e kōkua ai kēia mau mea i nā manaʻo ʻē aʻe?

• I loko o ka ʻōpū liʻiliʻi: Kōkua kēia mau capillaries i ka omo ʻana i nā meaola mai ka meaʻai a mākou e ʻai ai. ʻAe kēia mau lua i nā mea e like me nā huaora a me nā minelala e komo maʻalahi i ke koko.
• Inā ʻoe e lawe i ka pancreas: He mea nui e hoʻohui i nā enzymes a me nā hormones i ke koko e kōkua i ka hoʻoheheʻe ʻana i ka meaʻai, ʻoiai ke kō a me ka momona.
• Mai nā kelepa endocrine:Hoʻouna kēia mau kelepa i nā hormones ma loko o ko kākou kino. Hoʻomalu kēia mau hormones i nā mea he nui, me ko kākou ʻano a me ka ulu ʻana. Pono pū kēia mau capillaries i ke kōkua me kēlā.

Pehea ke ʻano o kēia mau capillaries fenestrated?

E noʻonoʻo i ka liʻiliʻi o kēia mau capillaries. ʻO ka hapa nui o nā capillaries he 3 a 4 micrometers wale nō ka laulā. ʻO ia ka nui o ka pūnaewele nananana! He palupalu loa, ʻeā? He ʻelua papa o nā cell ko lākou.

ʻO ka papa o loko o nā cell ua kapa ʻia he mau cell endothelial . ʻO ka papa o waho ua kapa ʻia he mau cell epithelial . I kekahi manawa kapa ʻia kēia e nā kauka ʻo ka basement membrane .

ʻIke ʻia nā capillaries fenestrated e nā lua liʻiliʻi i loko o ko lākou papa o loko. Loaʻa i kēlā me kēia lua (a i ʻole 'puka makani') kahi membrane lahilahi. Hana ia e like me ka diaphragm , kahi uhi liʻiliʻi e hiki ke wehe a pani ʻia. ʻAe kēia membrane i nā ʻāpana nui (e like me nā minelala) e hele maʻalahi ma o kēia mau lua.

He aha nā maʻi e hoʻopilikia ai i kēia mau capillaries?

No laila, ʻoiai nā capillaries fenestrated, e hana ana i kahi hana koʻikoʻi, hiki i kekahi manawa ke hoʻomohala i nā maʻi.

• Maʻi Puʻupaʻa Mau Loa (CKD): Loaʻa pinepine i ka poʻe me kēia maʻi nā pilikia me kēia mau capillaries. ʻOi aku hoʻi, hiki ke hōʻino ʻia nā capillaries peritubular i loko o nā puʻupaʻa. Kōkua kēia i ka kānana ʻana i nā huahana ʻōpala mai nā puʻupaʻa. Hiki i ka nele o ka Vitamin D, ka mumū, a me nā maʻi like ʻole ke hōʻino i kēia mau capillaries a hoʻemi i ko lākou nui. Kapa nā kauka i kēia ʻano he capillary rarefaction . Ke hana ʻia kēia, ʻaʻole hana pono kāu mau capillaries. Hiki i kēia ke alakaʻi i ka hypertension , ʻo ia hoʻi ke koko kiʻekiʻe, a me nā pilikia olakino ʻē aʻe.
• ʻO nā maʻi puʻupaʻa ʻē aʻe: ʻO nā maʻi puʻupaʻa ʻē aʻe, e like me ka glomerulonephritis, hiki ke hoʻopilikia i ke kaʻina kānana holoʻokoʻa o nā puʻupaʻa. He mea maʻamau ka maʻi puʻupaʻa. Inā ʻaʻole mālama pono ʻia, hiki iā ia ke alakaʻi i ka hāʻule ʻana o nā puʻupaʻa .

ʻAʻohe o kākou makemake e loaʻa nā pilikia o ka puʻupaʻa, no laila he mea nui e makaʻala i kēia mau mea.

• ʻO ka Systemic Capillary Leak Syndrome (SCLS): He kūlana kakaikahi loa kēia, akā he mea hoʻoweliweli paha i ke ola. Hoʻopilikia ia i nā paia o nā capillaries. Hiki i kēia ke hoʻohaʻahaʻa koke i ke koko.

Pehea lā e mālama ai i ke olakino o kēia mau capillaries fenestrated?

I kēia manawa, ke noʻonoʻo nei paha ʻoe, 'ʻAe, inā he mea nui kēia mau mea, pehea lā mākou e mālama ai iā lākou i ke olakino?' ʻOiaʻiʻo, i mea e mālama ai i ke olakino o kēia mau capillaries fenestrated, pono mākou e makaʻala i ko mākou olakino holoʻokoʻa . Kōkua kēia mau capillaries i nā ʻōnaehana he nui i loko o ko mākou kino e hana pono. He ʻāpana lākou o kā mākou ʻōnaehana hoʻopuni koko . Hoʻokomo pū kēlā ʻōnaehana i nā kīʻaha koko ʻē aʻe, nā aʻa, a me nā veins.

Hiki i nā ʻano maʻi vascular like ʻole, a i ʻole nā ​​maʻi e pili ana i nā kīʻaha koko, ke hoʻopilikia i ka hana o nā ʻano capillaries āpau. No laila, aia kekahi mau mea hiki iā mākou ke hana e pale aku iā mākou iho mai kēia mau maʻi a me nā pilikia olakino ʻē aʻe:

• He mea nui e hoʻoikaika kino a noho ikaika. He mea nui loa ka hoʻoikaika kino i kēlā me kēia lā.
• ʻO ka ʻai ʻana i ka meaʻai kaulike, ka palena ʻana i ka waiʻona, a me ke koho ʻana i nā meaʻai olakino no ka puʻuwai. He mea kēia e kamaʻilio nei nā kānaka a pau i kēia mau lā, akā he mea nui maoli nō ia.
• Ka mālama ʻana i ke kaumaha olakino. Inā kaumaha a momona paha ʻoe, e hoʻāʻo e hoʻēmi i ke kaumaha.
• Inā loaʻa iā ʻoe nā maʻi mau e like me ka maʻi diabetes mellitus a me ke koko kiʻekiʻe , he mea nui e kaohi pono iā lākou. Pono ʻoe e hahai pono i nā ʻōlelo a ke kauka.
• Inā he mea puhipaka ʻoe, e hoʻōki. ʻAʻole kēia he mea e lawe māmā ʻia, ʻo ia ke kumu o nā maʻi he nui.

Āhea mākou e ʻike ai i ke kauka e pili ana i kēia mau capillaries?

ʻAʻole mākou e hele pinepine i ke kauka me ka noʻonoʻo ʻana i nā capillaries. Eia nō naʻe, inā kū mai kekahi mau hōʻailona, ​​​​hiki ke ma muli o kahi pilikia me kēia mau capillaries fenestrated.

Nā hōʻailona o ka maʻi puʻupaʻa:

Pono ʻoe e ʻimi koke i ke kōkua lapaʻau, ʻoiai inā ʻoe e hōʻike ana i nā hōʻailona o ka maʻi puʻupaʻa. E nānā e ʻike inā loaʻa iā ʻoe kēia mau hōʻailona:

• Nā loli i ka mimi: Hiki i kēia ke komo pū me ke koko i loko o ka mimi (hematuria) , ka protein i loko o ka mimi (proteinuria) , a i ʻole ka pono pinepine e mimi.
• Luhi mau, paʻakikī i ka noʻonoʻo ʻana, a pilikia paha i ka hiamoe.
• ʻAʻohe ʻono o ka meaʻai.
• Inā he pehu a pupuhi paha a puni nā maka no nā lā he nui.
• ʻŌpū ʻiʻo.

Inā loaʻa iā ʻoe kekahi a ʻoi aku paha o kēia mau hōʻailona, ​​e ʻoluʻolu e ʻike koke i ke kauka. ʻOiai he mea maʻamau kēia i kekahi manawa, he mea nui e ʻike mua i kahi pilikia o ka puʻupaʻa.

Nā Hōʻailona o ka Systemic Capillary Leak Syndrome (SCLS):

ʻO kēlā kūlana laha ʻole i ʻōlelo ʻia ma mua, ʻo Systemic Capillary Leak Syndrome (SCLS), kahi e hāʻule koke ai ke koko. He pilikia olakino kēia. Inā hāʻule koke kou koko a loaʻa iā ʻoe kekahi o kēia mau hōʻailona, ​​​​pono ʻoe e ʻike koke i ke kauka a i ʻole e hele i kahi lumi pilikia:

• ʻEha ʻōpū a me ka luaʻi.
• Ke ʻū ʻana a me ka manaʻo e like me ka ʻū ʻana o ka umauma.
• ʻO ka pehu ʻana (edema), ʻoiai ma nā wāwae a me nā lima.
• Ka luhi nui loa.
• ʻEha poʻo.
• Māmā ke poʻo, poniuniu a me ka māʻule ʻana.

ʻO ka leka a mākou e makemake ai e lawe i ka home

ʻAe, no laila ke manaʻo nei au ua maopopo iā ʻoe kēia mau capillaries fenestrated a mākou i kamaʻilio ai i kēia lā. E hoʻomanaʻo, ʻo kēia mau kīʻaha koko liʻiliʻi 'windowed' he ʻāpana koʻikoʻi loa ia o kā mākou ʻōnaehana kahe koko. He mea nui lākou no ka kānana ʻana i nā ʻōpala mai ko mākou mau puʻupaʻa, ka hana ʻana i ka mimi, ka omo ʻana i nā meaʻai mai ko mākou ʻōpū, a me ka hoʻouna ʻana i nā hormones ma loko o ko mākou kino.

No laila, i mea e ola ai kēia mau capillaries liʻiliʻi akā ikaika, pono mākou e mālama i ko mākou olakino holoʻokoʻa . E ʻai i kahi meaʻai kaulike, e mālama i ke kaumaha olakino, e noho ikaika, a e loaʻa nā nānā mau e like me ka ʻōlelo a ke kauka. E hana kēia mau mea i kahi lawelawe maikaʻi loa i kā mākou 'puka makani' liʻiliʻi a me ko mākou kino holoʻokoʻa. Ua maopopo iā ʻoe?

Inā he mau nīnau hou aku kāu e pili ana i kēia, mai kānalua e kamaʻilio me kāu kauka ʻohana. E hiki iā ia ke hāʻawi iā ʻoe i ka ʻike hou aku.

Nā Capillaries Fenestrated, Capillaries, Nā puʻupaʻa, Nā Nephrons, Ke Kaʻapuni Koko, Ola Kino