ʻO ka maʻi ʻo Addison | E aʻo kākou e pili ana i nā kumu, nā hōʻailona a me ka mālama ʻana i nā huaʻōlelo maʻalahi

Ke manaʻo nei ʻoe i ka luhi a me ka palaualelo i kēlā me kēia lā? Me ka ʻeha o ka ʻōpū a me ka nausea, loaʻa iā ʻoe i kekahi manawa kahi makemake ʻē no nā meaʻai paʻakai? ʻOiai ke ʻano o kēia mau mea he mau mea maʻamau, malia paha ma hope o kēia he kūlana i lohe ʻole ʻia e mākou, akā pono e mālama pono ʻia. I kēia lā, ke kamaʻilio nei mākou e pili ana i kekahi ʻano maʻi, ʻo ia ka maʻi ʻo Addison.

He aha maoli ka maʻi ʻo Addison?

I ka ʻōlelo maʻalahi, ʻo ka maʻi ʻo Addison kahi maʻi mau loa e kū mai ana i ka wā ʻaʻole lawa ka hana ʻana o nā kelepa adrenal i loko o ko mākou kino i ʻelua mau hormones koʻikoʻi, cortisol a me aldosterone .

I kēia manawa ke noʻonoʻo nei paha ʻoe i ke ʻano o nā kelepa adrenal. He ʻelua mau kelepa liʻiliʻi, triangular e noho ana e like me ka pāpale ma luna o ko kākou mau puʻupaʻa. He ʻāpana koʻikoʻi lākou o ka ʻōnaehana endocrine o ko kākou kino.

• Cortisol: He mea nui kēia hormone i ko kākou ola. E noʻonoʻo i ka wā e maʻi ai ʻoe, loaʻa i kahi ulia, a i ʻole e hana ʻia ke ʻoki kino, nui ke kaumaha o kou kino. I kēlā mau manawa, kōkua ka hormone cortisol i ke kino e hoʻomanawanui i kēlā kaumaha. ʻAʻole wale ia, akā kōkua pū ia i ka hoʻomalu ʻana i ke koko, ka hana o ka puʻuwai, ka ʻōnaehana pale, a me nā pae kō koko.

• ʻAldosterone: Hoʻoponopono kēia hormone i ke kaulike o ka sodium (paʻakai) a me ka potassium i loko o ko kākou koko. Hoʻomalu pū ia i ka nui o ka wai e hoʻokuʻu ʻia e ko kākou mau puʻupaʻa ma ke ʻano he mimi. Hoʻopilikia pololei kēia i ka nui o ko kākou koko a me ke kaomi koko.

Ua ʻike ʻia hoʻi ka maʻi ʻo Addison ʻo ka hemahema adrenal mua . Aia kekahi kūlana pili i kapa ʻia ʻo ka hemahema adrenal lua . Ma kēia kūlana, ʻaʻole hana ka pituitary gland i loko o ka lolo i ka nui o ka hormone i kapa ʻia ʻo ACTH . Hoʻoulu kēia hormone, ACTH, i nā kelepa adrenal e hana i ka cortisol.

He aha ka ʻokoʻa ma waena o ka maʻi ʻo Addison a me ka maʻi ʻo Cushing?

Mai huikau i nā mea ʻelua. He mea maʻalahi loa ia.

• ʻO ka maʻi ʻo Addison: ʻAʻole lawa ka cortisol (a me ka aldosterone) i loko o ke kino.
• ʻO Cushing's Syndrome: Hoʻonui ʻia ka cortisol i loko o ke kino.

ʻO wai ka mea kūpono loa e loaʻa i kēia maʻi?

ʻOiai hiki ke loaʻa ka maʻi ʻo Addison i kēlā me kēia makahiki, ʻoi aku ka maʻamau ma waena o 30 a me 50 mau makahiki.I waena o nā kānaka. He maʻi laha ʻole kēia.

Eia kekahi, ʻoi aku ka nui o ka pilikia o ka poʻe me kekahi mau maʻi autoimmune i ka loaʻa ʻana o ia mea. ʻO kahi maʻi autoimmune ka wā e hoʻouka hewa ai ka ʻōnaehana pale ponoʻī o ko mākou kino i kā mākou mau hunaola olakino ponoʻī. ʻOi aku ka nui o ka pilikia o ka poʻe me kēia mau maʻi i ka loaʻa ʻana o ka maʻi ʻo Addison:

• ʻAno I diabetes
• ʻO ka anemia ʻino
• Maʻi Graves
• ʻO ka thyroiditis mau loa
• ʻO ka ʻili herpetiformis
• ʻO ka ʻili ʻili
• ʻO ka maʻi ʻaʻai

He aha nā hōʻailona o ka maʻi ʻo Addison?

I kēia maʻi, lohi pinepine ka hōʻino ʻana i nā kelepa adrenal, i ka hala ʻana o ka manawa. No laila, ʻike mālie ʻia nā hōʻailona. Hiki ke ʻokoʻa kēia mau hōʻailona mai kēlā kanaka a kēia kanaka.

Inā loaʻa i nā wāhine kēia maʻi, hiki iā lākou ke ʻike i nā hōʻailona e like me nā pōʻaiapuni menstrual kūpono ʻole, ka nalowale o ka lauoho o ke kino, a me ka emi ʻana o ka makemake i ka moekolohe.

Pilikia: He aha ka pilikia Addisonian?

I kekahi manawa, ʻoiai i nā manawa o ke kaumaha nui ma ke kino (e.g., kahi maʻi koʻikoʻi, kahi ulia), hiki i nā hōʻailona ke ʻoi aku ka ʻino a lilo i mea hoʻoweliweli i ke ola. Ua kapa ʻia kēia he pilikia Addisonian , a i ʻole ka hemahema adrenal acute .

Inā loaʻa iā ʻoe a i ʻole kekahi āu i ʻike ai nā hōʻailona ma lalo nei, e lawe koke iā lākou i ka ʻOihana Pilikia (ETU) o ka haukapila kokoke loa.

He aha ke kumu o ka maʻi ʻo Addison?

ʻO ke kumu nui o ka maʻi ʻo Addison he pane autoimmune . I ka ʻōlelo maʻalahi, hoʻouka hewa ka ʻōnaehana pale ponoʻī o ko mākou kino (ka ʻōnaehana pale) i kā mākou mau ʻiʻo olakino ponoʻī. I loko o kēia maʻi, hoʻouka ka ʻōnaehana pale i ka ʻaoʻao waho o nā kelepa adrenal (ka cortex adrenal). Maanei kahi e hana ʻia ai ka cortisol a me ka aldosterone. ʻAʻole ʻike pinepine ʻia nā hōʻailona a hiki i ka 90% o kēia pōʻino i hana ʻia. Hiki i kēia ke hala i nā mahina, a i ʻole nā ​​​​makahiki. ʻO kēia ke kumu o 75% o nā maʻi o Addison.

I ka wā ma mua, ʻo ka maʻi puʻupuʻu ke kumu nui o kēia, a he kumu nui nō ia ma nā ʻāina e ulu ana.

Aia kekahi mau kumu kākaʻikahi ʻē aʻe:

• Nā maʻi e like me ka maʻi HIV/AIDS a me nā maʻi fungal.
• ʻO ka laha ʻana o nā hunaola maʻi ʻaʻai mai nā wahi ʻē aʻe a i nā kelepa adrenal.
• Ke kahe ʻana o ke koko i loko o nā kelepa adrenal (hemorrhaging).
• Wehe ʻoki kino ʻana i nā kelepa adrenal.
• Nā maʻi e like me ka amyloidosis.

Pehea e ʻike ai ke kauka i kēia maʻi?

Ma muli o ka ʻike mālie ʻia ʻana o nā hōʻailona a he mea maʻamau ia i nā maʻi ʻē aʻe he nui, hiki ke paʻakikī ke ʻike pololei i kēia maʻi.

I ka manawa pinepine, lilo ke kauka i mea kānalua ke hōʻike kahi hoʻāʻo koko maʻamau i nā pae sodium haʻahaʻa a i ʻole nā ​​​​pae potassium kiʻekiʻe i loko o ke koko. ʻO nā wahi ʻeleʻele ma ka ʻili kekahi hōʻailona nui e kānalua ai kekahi i kēia.

Inā kānalua kāu kauka i ka maʻi o Addison ma muli o kāu mau hōʻailona, ​​​​e kauoha lākou i kekahi mau hoʻokolohua hou aʻe e hōʻoia i ka hōʻailona.

• Nā hoʻāʻo koko: Ke ana kēia i nā pae o ka sodium, potassium, cortisol, a me nā hormones ACTH i loko o kou koko.
• Hoʻāʻo hoʻoulu ACTH: Pili kēia i ka hoʻokomo ʻana i kahi hormone ACTH synthetic a nānā inā hana kāu mau kelepa adrenal i ka cortisol i ka pane. ʻO nā pae cortisol haʻahaʻa e hōʻike paha ua hana ʻole nā ​​​​kelepa.
• Hoʻāʻo hypoglycemia i hoʻokomo ʻia e ka insulin: Nānā kēia e ʻike inā pili kāu pilikia i ka pituitary gland.
• CT scan: Hiki i kēia ke nānā no ka hōʻino ʻia o nā kelepa adrenal a i ʻole ka maʻi.

He aha nā lāʻau lapaʻau no kēia?

Hoʻōla ʻia ka maʻi ʻo Addison ma ka hoʻololi ʻana i nā hormones i nalowale o ke kino me nā lāʻau synthetic.

• Hāʻawi ʻia kahi lāʻau i kapa ʻia ʻo hydrocortisone ma kahi o cortisol.
• Ua pani ʻia ʻo Aldosterone me kahi lāʻau i kapa ʻia ʻo fludrocortisone .

ʻOkoʻa ka nui o kēia lāʻau lapaʻau mai kēlā kanaka a kēia kanaka. Eia kekahi, hiki i kāu kauka ke hoʻonui i ka nui o ka lāʻau lapaʻau e pale aku i kahi pilikia Addisonian inā loaʻa iā ʻoe ke kaumaha, e like me ka maʻi, kahi ulia, a i ʻole ke ʻoki kino.

Inā loaʻa iā ʻoe ka maʻi ʻo Addison, pehea ʻoe e mālama ai iā ʻoe iho?

Inā loaʻa iā ʻoe kēia maʻi, he mea nui loa ia e mālama iā ʻoe iho.

• E hoʻokomo mau i kahi kāleka ID a i ʻole ke kūpeʻe lima makaʻala lapaʻau i hiki i nā kauka lapaʻau ke ʻike e pili ana i kou kūlana inā he pilikia.
• E kamaʻilio me kāu kauka e pili ana i ka mea e hana ai ke maʻi ʻoe a i ʻole ke kaumaha nui, no ka mea, pono e hoʻoponopono ʻia ka nui o kāu lāʻau i nā manawa e like me kēia.
• No kahi pilikiaE nīnau i kāu kauka e pili ana i ka mālama ʻana i kahi inikini cortisol ma ka lima a me ke aʻo ʻana i kahi lālā o ka ʻohana pehea e hāʻawi ai iā ʻoe.

Āhea ʻoe e ʻike ai i kāu kauka?

Inā loaʻa iā ʻoe ka maʻi ʻo Addison, pono ʻoe e ʻike i kāu kauka (pinepine he endocrinologist) i nā manawa a pau e hōʻoia i ka kūpono o kāu lāʻau lapaʻau iā ʻoe.

Inā loaʻa iā ʻoe kahi mea hoʻoluhi nui, e like me kahi ulia, maʻi, a i ʻole ka make ʻana o kahi mea aloha, e kāhea i kāu kauka no ka mea pono paha ʻoe e hoʻololi i ka nui o kāu lāʻau lapaʻau.

ʻO ka ʻike ʻana he maʻi mau kou hiki ke hoʻopilikia i ka naʻau. Akā ʻo ka nūhou maikaʻi, hiki ke mālama pono ʻia ka maʻi ʻo Addison me ka lāʻau lapaʻau. Ma ka ʻike pinepine ʻana i kāu kauka, ka lawe ʻana i ka nui kūpono o ka lāʻau lapaʻau, a me ka mālama ʻana iā ʻoe iho, hiki iā ʻoe ke ola i kahi ola olakino a maʻamau.