Ua ʻike mākou he hana paʻakikī ke mālama ʻia ʻana no ka maʻi kanesa. He mea maʻamau ka hiki ʻana mai o nā nīnau i ka noʻonoʻo ke haʻi aku kāu kauka i kahi lāʻau hou. I kēia lā, e kamaʻilio mākou e pili ana i kekahi lāʻau lapaʻau anti-cancer kūikawā, ʻo Aldesleukin. Ua kapa ʻia hoʻi ʻo IL-2 i kekahi manawa. E nānā kākou i ke ʻano o kēia lāʻau, kāna hana, a me nā mea e pono ai ʻoe e ʻike e pili ana iā ia i ka wā e lawe ai.
He aha ke ʻano lāʻau lapaʻau ʻo Aldesleukin?
I ka ʻōlelo maʻalahi, he lāʻau lapaʻau kanesa ʻo Aldase. Akā, ʻaʻole ia e like me nā lāʻau chemotherapy a mākou e lohe pinepine ai. He immunotherapy maoli nō ia. ʻO ia hoʻi, ma mua o ka pepehi pololei ʻana i nā hunaola kanesa, hoʻoulu ia i kāu ʻōnaehana pale ponoʻī a hāʻawi iā ia i ka ikaika e hakakā i nā hunaola kanesa . Ua like ia me ke aʻo ʻana i nā "koa" (nā hunaola pale) i loko o ko mākou kino a hoʻouna iā lākou i ke kaua kūʻē i ka ʻenemi i kapa ʻia ʻo ke kanesa.
Hoʻohana nui ʻia kēia lāʻau lapaʻau (inoa inoa: Proleukin) no:
- No ke kanesa o nā cell renal ʻaʻohe ona a holomua paha .
- No ka melanoma holomua, kahi maʻi ʻili koʻikoʻi.
I kekahi mau hihia, hiki i nā kauka ke ʻōlelo aku i kēia lāʻau lapaʻau no nā ʻano maʻi ʻē aʻe.
ʻO nā mea nui e haʻi aku i kāu kauka ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau
Ma mua o ka hoʻoholo ʻana inā kūpono kēia lāʻau lapaʻau iā ʻoe, he mea nui e hoʻomaopopo i kāu kauka e pili ana i kou mōʻaukala olakino piha. E hōʻoia e haʻi iā lākou e pili ana i kekahi o kēia mau kūlana, ʻoi aku hoʻi:
- Inā he mau pilikia koko kou (e like me nā pilikia o ke kāpili ʻana o ke koko, anemia).
- Inā ʻoe e luhi mau ana a luhi paha .
- Inā loaʻa iā ʻoe ke kuni a i ʻole kekahi maʻi lele ʻē aʻe i loko o ke kino.
- Inā he maʻi kou no ka puʻuwai, ka māmā, nā puʻupaʻa a i ʻole ke akepaʻa .
- Inā he mau pilikia ʻē aʻe kāu o ka ʻōnaehana pale .
- Inā loaʻa iā ʻoe kahi maʻi noʻonoʻo (e.g. kaumaha) a i ʻole ke lawe nei ʻoe i ka lāʻau lapaʻau no ia mea.
- Inā ua loaʻa iā ʻoe kahi hoʻoili kino ma mua.
- Inā loaʻa iā ʻoe nā ʻōʻili .
- Inā he mau pilikia ʻōpū a i ʻole nā maʻi o ka ʻōnaehana hoʻoheheʻe.
- Inā he mau pilikia kou me ka thyroid .
- Inā loaʻa iā ʻoe kahi hopena maʻi i ka aldesleukin a i ʻole kekahi lāʻau lapaʻau ʻē aʻe, meaʻai, a mea hoʻoluʻu paha .
- Inā hāpai ʻoe, e hoʻāʻo ana e hāpai, a he makuahine hānai paha ʻoe .
He mea nui loa kēia ʻike no kou palekana, no ka mea, ma muli o kēia ʻike e hoʻoholo ai ke kauka i ka lāʻau kūpono a palekana loa nāu.
Pehea e hāʻawi ʻia ai kēia lāʻau lapaʻau iā ʻoe?
ʻAʻole kēia he lāʻau lapaʻau hiki iā ʻoe ke lawe i ka home. Hāʻawi ʻia ʻo Aldase ma kahi haukapila a i ʻole ke keʻena lapaʻau, ma lalo o ka nānā pono ʻana o nā kauka a me nā kahu maʻi . Hāʻawi pinepine ʻia ia ma ke ʻano he injection i loko o kahi vein (intravenous a i ʻole IV) . I kekahi manawa hiki ke hāʻawi ʻia ma ke ʻano he injection ma lalo o ka ʻili (subcutaneous injection).
ʻOiai ua hāʻawi ʻia kēia lāʻau lapaʻau ma kahi haukapila, ʻaʻole pono ʻoe e hopohopo e pili ana i ka hala ʻana o kahi lāʻau a i ʻole ka loaʻa ʻana o ka overdose. E mālama pono ke kime lapaʻau iā ia.
Inā manaʻo ʻoe ua lawe hewa ʻoe i ka lāʻau lapaʻau, e hoʻomaopopo koke i ke kauka a i ʻole ke kahu maʻi. I kekahi pilikia, hiki iā ʻoe ke hele i ka Emergency Treatment Unit (ETU) o ka haukapila, a inā he pilikia lāʻau make, hiki iā ʻoe ke kelepona i ke National Poisons Information Centre ma ka Halemai Lahui ʻo Colombo .
E makaʻala i nā lāʻau lapaʻau ʻē aʻe āu e lawe ai.
I ka wā e lawe ana iā aldesleukin, he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei. Hiki i kekahi mau lāʻau lapaʻau ke launa pū me kēia lāʻau lapaʻau. No laila, pono ʻoe e lawe:
- Nā lāʻau lapaʻau anticancer ʻē aʻe (e.g. doxorubicin, methotrexate)
- Nā lāʻau antibiotic, ʻoiai hoʻi nā aminoglycosides
- Nā lāʻau lapaʻau no ke koko kiʻekiʻe (e like me nā beta blockers)
- Nā lāʻau lapaʻau noʻonoʻo (no ke kaumaha, ka hopohopo)
- Nā ʻano steroid (e.g. prednisone, cortisone)
- Nā lāʻau hoʻopau ʻeha, ʻoi aku hoʻi nā NSAID (e.g. ibuprofen, naproxen)
- Nā lāʻau hiamoe
- ʻO nā lāʻau lapaʻau immunosuppressive ʻē aʻe e like me interferon alfa
Ma waho aʻe o kēia papa inoa, mai poina e haʻi i kāu kauka e pili ana i nā huaora, nā mea hoʻopihapiha lāʻau lapaʻau āu e lawe ai, a inā ʻoe e puhipaka a inu waiʻona paha .
Nā mea e makaʻala nui ai i ka wā o ka mālama ʻana
- Ka nānā mau ʻana: E nānā pono ʻia ʻoe e nā kauka a me nā kahu maʻi i ka manawa holoʻokoʻa o kēia lāʻau lapaʻau.
- Nā hoʻāʻo koko: Pono ʻoe e loaʻa i nā hoʻāʻo koko maʻamau e nānā i ka holomua o kāu lāʻau lapaʻau a ʻike koke i nā hopena ʻaoʻao.
- Ka palekana ʻana mai nā maʻi: Hiki i kēia lāʻau lapaʻau ke hōʻemi i ka hiki o ke kino ke hakakā i nā maʻi no kekahi manawa. No laila,E hoʻāʻo e noho mamao aku mai ka poʻe i loaʻa i ke anu a i ʻole ka maʻi palū. Inā loaʻa iā ʻoe ke kuni a i ʻole ka maʻi i ka wā e lawe ana i ka lāʻau lapaʻau, mai hoʻōla ponoʻī a e hoʻomaopopo koke i kāu kauka.
- Nā ʻeha maʻamau: He mea maʻamau ke manaʻo iki i ka ʻoluʻolu ʻole a maʻi paha i ka wā e lawe ana i kēia lāʻau. He ʻāpana kēia o ka lāʻau lapaʻau. Eia nō naʻe, e hoʻomaopopo i kāu kauka e pili ana i nā hōʻailona hou a i ʻole nā pilikia āu e ulu ai.
He aha nā hopena ʻaoʻao e hiki ke loaʻa mai ka lāʻau lapaʻau?
E like me nā lāʻau lapaʻau āpau, hiki i ka aldesleukin ke hana i nā hopena ʻaoʻao. Pono kekahi o kēia mau mea i ka mālama koke ʻana o ke kauka, aʻo kekahi he emi iki ka koʻikoʻi.
| Nā hopena ʻaoʻao e pono e hōʻike koke ʻia i ke kauka/kahu hānai | |
|---|---|
| Hōʻailona | Wehewehena |
| Nā maʻi ʻaleʻale koʻikoʻi | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, nā lehelehe a i ʻole ke alelo. |
| Paʻakikī ka hanu ʻana | Paʻakikī ka hanu ʻana, ke kani ʻana o ka wheezing mai ka umauma mai. |
| Nā pilikia o ka puʻuwai | ʻEha umauma, puʻuwai wikiwiki a ʻano ʻole paha. |
| Nā loli noʻonoʻo | Ka huikau, ka hoʻomaha ʻole, ka hopohopo, ka ʻike ʻana a i ʻole ka lohe ʻana i nā mea ʻoiaʻiʻo ʻole (hallucinations). |
| Nā pilikia puʻupaʻa | Ka emi ʻana o ka mimi ʻana, ka mimi melemele ʻeleʻele a ʻeleʻele paha. |
| Nā pilikia o ke akepaʻa | Melemele o nā maka a me ka ʻili. |
| Nā hōʻailona koʻikoʻi ʻē aʻe | ʻO ka pōniuniu nui, ka hiamoe, ke kahe ʻana o ke koko a i ʻole ka palapū ʻana, ka pehu ʻana o ke kino (ʻoi aku hoʻi ka maka a me nā wāwae), ka luhi nui, ka luaʻi ʻana, ke kuni, ka anu, ka ʻāʻī ʻeha. |
| Nā mea i maʻa mau ʻole i ka nui, akā pono e hōʻike ʻia i ke kauka inā hoʻomau lākou | |
|---|---|
| Ka pehu ʻana (ka maʻi kahe) | Ka luaʻi |
| Hiamoe | Makemake nui |
| ʻEha waha | ʻEha ʻōpū |
Inā loaʻa iā ʻoe kekahi mau hōʻailona ʻē aʻe i ʻōlelo ʻole ʻia ma kēia papa inoa, e ʻoluʻolu e hoʻomaopopo i kāu kauka a kahu maʻi paha e pili ana iā lākou.
Leka Lawe-Home
- He lāʻau kūikawā ʻo Aldesleukin/IL-2 e kōkua ai i ke kaua ʻana i ka maʻi kanesa ma o ka hoʻoulu ʻana i ka ʻōnaehana pale o kou kino ponoʻī, ma mua o ka pepehi pololei ʻana i nā hunaola kanesa.
- Hāʻawi ʻia kēia lāʻau lapaʻau ma ka haukapila, ma lalo o ka mākaʻikaʻi a ke kauka, no laila ʻaʻole pono ʻoe e hopohopo e pili ana i ka nui o ka lāʻau a i ʻole ka mālama ʻana i ka lāʻau.
- Ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau, e hōʻoia e haʻi i kāu kauka e pili ana i nā maʻi ʻē aʻe āu e loaʻa nei a me nā lāʻau lapaʻau āu e lawe nei (me nā huaora a me nā mea kanu).
- Inā loaʻa iā ʻoe kekahi mau hopena koʻikoʻi i ka wā o ka mālama ʻana, e like me ke kuni, ka paʻakikī o ka hanu ʻana, ka ʻeha o ka umauma, a i ʻole ka pehu nui, e hoʻomaopopo koke i ke limahana lapaʻau.
- Hiki ke paʻakikī kēia lāʻau lapaʻau, akā ʻaʻole ʻoe hoʻokahi. Ua mākaukau mau kāu hui lapaʻau e kōkua iā ʻoe. Mai makaʻu e kamaʻilio me lākou e pili ana i nā nīnau a hopohopo paha.
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