Ke ʻike nei ʻoe i kekahi manawa i ka pehu koke ʻana o kou kino? He angioedema paha ia!

Ua ʻike anei ʻoe ua pehu koke kou mau lehelehe, a i ʻole e pehu ana kou mau maka? I kekahi manawa, pehu kou helehelena holoʻokoʻa, a me kou mau lima a me kou mau wāwae. He mea maʻamau ke manaʻo iki i ka makaʻu ke hana ʻia kekahi mea e like me kēia. ʻO ka hapa nui o ka manawa, ua hoʻokumu ʻia kēia e kahi maʻi i kapa ʻia ʻo angioedema . E kamaʻilio kākou e pili ana i kēia me nā kikoʻī, maʻalahi loa, ʻae?

He aha ka Angioedema? E hoʻomaopopo maʻalahi kākou!

I ka ʻōlelo maʻalahi, ʻo Angioedema ka pehu ʻana o nā ʻiʻo ma lalo o ko mākou ʻili, ʻoiai ka dermis, ka papa o loko o ka ʻili, a i ʻole nā ​​papa ma lalo o ka membrane mucous. Hana ʻia kēia ma ke ʻano he pane i kekahi mea. Ua lohe paha ʻoe i kahi maʻi i kapa ʻia ʻo urticaria , a i ʻole hives . Hoʻopili pinepine ʻia ka angioedema a me nā hives, a ua like loa nā kumu. I nā hihia ʻelua, kahe ka wai mai ko mākou mau kīʻaha koko liʻiliʻi i loko o nā ʻiʻo, e hoʻoulu ai i nā wahi e pehu.

Hoʻomaka koke ka angioedema a emi iho i loko o hoʻokahi a ʻelua paha lā. Hoʻopilikia nui ia i nā lehelehe a puni nā maka . Akā, e noʻonoʻo, inā hoʻopilikia kēia pehu i ko mākou ala ea , hiki ke lilo i mea weliweli loa, a hiki ke hoʻoweliweli i ke ola . No laila pono mākou e makaʻala no kēlā.

He aha nā ʻano nui o ka angioedema?

Aia kekahi mau ʻano angioedema. Hiki i nā hui olakino like ʻole ke hoʻokaʻawale iā lākou i nā ʻano like ʻole, akā ma ke ʻano laulā, hiki iā mākou ke ʻike i kekahi mau ʻano nui.

1. ʻO ka angioedema allergic koʻikoʻi

ʻO kēia paha ke ʻano āu i lohe ai a ʻike nui ai. Hana ʻia ia ke hōʻike ʻia ʻoe i kahi mea āu e maʻi ai . Hiki paha kēia i kahi mea āu i ʻai ai (kahi meaʻai, kahi mea inu), lawe i kahi lāʻau lapaʻau, a hoʻopā paha (no ka laʻana, kahi mea i hana ʻia me ka latex rubber maoli). Hiki nō hoʻi ke hana ma hope o ka nahu ʻia ʻana e kahi pepeke a i ʻole ka nananana.

Hiki koke mai ka angioedema allergic acute, maʻamau i loko o kekahi mau minuke a i hoʻokahi a ʻelua paha hola, ma hope o ka hōʻike ʻana i ka allergen. Hoʻopili pinepine ʻia kēia pehu me nā hives.

2. ʻO Angioedema ma muli o kahi hopena lāʻau lapaʻau ʻaʻole allergic

ʻAʻole hiki koke mai kēia ʻano angioedema ma hope o kou lawe ʻana i kahi lāʻau lapaʻau. ʻO ka papa nui o nā lāʻau lapaʻau e hoʻoulu ai i kēia hopena ʻaʻole allergic he angiotensin-converting enzyme inhibitors , a i ʻole ACE inhibitors a i ʻole ACEIs no ka pōkole.Hoʻohana pinepine ʻia kēia mau lāʻau lapaʻau e hoʻonui i nā kīʻaha koko, mālama i nā maʻi puʻuwai, a hoʻohaʻahaʻa i ke koko kiʻekiʻe. Hiki i nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) , e like me ka ibuprofen a me ka naproxen, ke hana i kēia ʻano angioedema.

3. Angioedema o ke kumu i ʻike ʻole ʻia (Idiopathic angioedema)

ʻO ke ʻano o ka huaʻōlelo " idiopathic" ʻo ia hoʻi "no ke kumu i ʻike ʻole ʻia." No laila, he paʻakikī ke loaʻa kahi kumu kikoʻī no kēia ʻano angioedema. ʻO ka maʻamau, ʻike ʻia ka pehu ʻana ma ka maka, nā lima, ke kino, a me nā wāwae. Loaʻa paha i kekahi poʻe nā pilikia o ka ʻōnaehana pale a me ke kaumaha.

4. ʻO ka angioedema hoʻoilina (HAE)

ʻO kēia ka angioedema hoʻoilina , i ʻike ʻia hoʻi ʻo HAE no ka pōkole. He mea kēia āu e loaʻa ai mai kou mau mākua ma o kāu mau genes. Hiki i nā keiki ke hoʻoilina iā ia ʻoiai inā hoʻokahi wale nō makua i loaʻa ka gene, a inā paha he maʻi ko lākou. Hiki i kekahi poʻe ke hoʻomohala i kēia ʻano angioedema ma muli o nā hoʻololi genetic spontaneous. Ua manaʻo ʻia aia ma kahi o 1 i loko o 50,000 mau kānaka e loaʻa i kēia ʻano angioedema hoʻoilina (HAE). ʻEkolu mau ʻano nui o kēia, pili kēlā me kēia i kekahi ʻano i nā pae o ka protein C1 a/a i ʻole ka mea hoʻopaʻa esterase C1 i loko o ko mākou koko.

5. Loaʻa ka angioedema hemahema o ka mea hoʻopaʻa C1

ʻO kēia ke kumu o ka angioedema, akā ʻaʻole ia he hoʻoilina. ʻO ke ʻano o ka "Acquired" ʻaʻole ʻoe i hānau ʻia me ka hemahema, akā loaʻa iā ʻoe ma hope o ke ola. E like me nā ʻano ʻē aʻe, hiki i kēia ʻano angioedema ke hoʻopilikia i kou larynx, a i ʻole ka windpipe, a hiki ke hoʻoulu i ka asphyxiation. Inā loaʻa iā ʻoe kahi maʻi e like me ka B-cell lymphoma, ua kapa ʻia kēia maʻi ʻo Acquired C1 inhibitor deficiency.

6. ʻO ka angioedema i hoʻokumu ʻia e ka haʻalulu (Vibratory angioedema)

Ma kēia kūlana, hoʻoulu ʻia ka pehu e nā haʻalulu mau. No ka laʻana, hiki ke hana ʻia kēia ke holo ʻoe i kahi mokokaikala, holo, jogging, loaʻa i kahi lomilomi ikaika, a i ʻole hana i nā hana like ʻē aʻe. ʻO ka angioedema vibratory kekahi ʻano o kahi kūlana kakaikahi i kapa ʻia ʻo urticaria inducible chronic . I loko o ia mea, ʻike ʻia nā hives i ka pane ʻana i nā stimuli o waho e like me ke anu, ka wela, ka wai, ke kaomi, a i ʻole ka haʻalulu. Hoʻomau nā ʻōpala ʻeha a mau no kahi o ʻeono pule.

ʻO wai ka mea e ʻoi aku ka nui o ka loaʻa ʻana o ka angioedema?

ʻOiaʻiʻo, hiki i kekahi ke loaʻa i ka angioedema. Ua manaʻo ʻia ma waena o 20% a me 25% o ka heluna kanaka ʻAmelika e loaʻa i ka angioedema a/a i ʻole urticaria ma ka liʻiliʻi hoʻokahi i ko lākou ola. No laila, he mea maʻamau kēia maʻi ma Sri Lanka.

He aha nā hōʻailona o ka angioedema? Pehea ʻoe e ʻike ai iā lākou?

ʻO nā hōʻailona nui o ka angioedema:

• Pehu a pehu paha ka maka , ʻoi aku hoʻi a puni nā maka a me ka waha, me nā lehelehe a me ke alelo. E noʻonoʻo i kou ala ʻana i ke kakahiaka a laila pehu koke kou mau lehelehe a paʻakikī ke ʻōlelo.
• Inā pehu kou ʻōpū, hiki iā ʻoe ke loaʻa nā pilikia ʻōpū . ʻO kēia ka ʻeha o ka ʻōpū, ka maʻi pākī, ka nausea, a me ka luaʻi.
• Ka pehu ʻana o nā lima, nā wāwae, a i ʻole nā ​​​​wahi genital.
• Hiki i nā loli i ke koko ke hana i nā mea e like me ka poniuniu a i ʻole ka māʻule ʻana .
• ʻO ka pehu ʻana o ka waha, ka ʻāʻī, a i ʻole nā ​​ala ea e hiki ai ke paʻakikī ke hanu a me ka ʻōlelo. ʻO kēia ka mea weliweli loa. Inā hana ʻia kekahi mea e like me kēia, he pilikia olakino ia. Pono ʻoe e hele koke i ka haukapila!

ʻO ka mea nui loa: Inā pehu kou puʻu a manaʻo ʻoe e pilikia ana ʻoe i ka hanu ʻana, ʻaʻole ia he mea hoʻohenehene. E ʻimi koke i ke kōkua lapaʻau.

No ke aha e hana ai ka angioedema? He aha nā kumu?

ʻOkoʻa nā kumu o ka angioedema ma muli o ke ʻano o ka angioedema āu e loaʻa ai. Eia nō naʻe, ʻo ke kumu maʻamau ka maʻi ʻaleka . Nui nā ʻano maʻi ʻaleka e hiki ke hoʻoulu ai:

• ʻAʻai maʻi: ʻO ka waiū, nā hua manu, nā nati e like me ka cashews, a me nā meaʻai kai e like me ka shellfish ke kuleana no kēia.
• Nā maʻi ʻaleka lāʻau: ʻO nā lāʻau antibiotic e like me ka penicillin a me nā lāʻau sulfa, nā lāʻau anti-inflammatory nonsteroidal (NSAID), a me nā mea hoʻohālikelike i hoʻohana ʻia i kekahi mau hoʻokolohua kiʻi hiki ke hana i kēia. Hiki i kēia mau ʻano maʻi ʻaleka ke hana i nā hives.
• Mea ʻawaʻawa: Ka mea ʻawaʻawa i hoʻopuka ʻia e nā nahu pepeke, a kākaʻikahi loa e nā holoholona e like me ka nananana recluse brown.
• ʻO ka latex rubber maoli: ʻO ka Latex kahi mea i hoʻohana ʻia e hana i nā mea e like me nā mikina lima, nā baluna, nā condom, a me nā catheters lapaʻau. Ua nīnau paha kāu kauka iā ʻoe inā he maʻi ʻoe i ka latex.

ʻO nā kumu ʻē aʻe e pili ana i nā pilikia hoʻoilina a me nā pilikia ma hope me ka protein C1 inhibitor, nā hopena lāʻau e kū mai me ka ʻole o ka maneʻo a i ʻole ka ʻulaʻula (ʻaʻole kēia he mau maʻi allergies maʻamau), a me nā neʻe haʻalulu.

He laha anei ka Angioedema?

ʻAʻole, ʻaʻole loa.ʻAʻole hiki iā ʻoe ke loaʻa i ka angioedema mai kekahi kanaka ʻē aʻe, ʻaʻole hoʻi hiki iā ʻoe ke hoʻolaha iā ia i kekahi kanaka ʻē aʻe. ʻAʻole ia he maʻi lele.

Pehea ʻoe e ʻike ai i ka angioedema? He aha nā mea a nā kauka e nānā ai?

Hiki ke paʻakikī ke ʻike pololei i ke ʻano o ka angioedema āu. E nānā mua kāu kauka iā ʻoe ma ke kino, akā i ka hapa nui o ka manawa e ʻike maʻalahi ʻia ka pehu. A laila e nīnau lākou iā ʻoe i kekahi mau nīnau:

• I ka manawa hea i hoʻomaka ai ka pehu?
• Ua ʻai anei ʻoe, inu, lawe, a hoʻopā paha i kekahi mea āu i manaʻo ai ua hoʻoulu i ka hopena?
• He aha nā lāʻau lapaʻau a me nā mea hoʻohui āu e lawe nei?
• Ua loaʻa anei kekahi hopena e like me kēia ma mua?
• Ua loaʻa i kekahi o kou ʻohana ka pehu e like me kēia?

Ma waho aʻe o ka nīnau ʻana i kēia mau nīnau, hiki i kāu kauka ke kauoha i nā hoʻāʻo koko a i ʻole nā ​​​​hoʻāʻo ʻili e nānā i nā maʻi allergies , a i ʻole nā ​​​​hoʻāʻo koko e nānā i ka angioedema e pili ana i ka protein C1 inhibitor.

He aha nā lāʻau lapaʻau no ka Angioedema?

ʻOkoʻa ka mālama ʻana no ka angioedema ma muli o ke ʻano āu e loaʻa ai.

• No nā maʻi ʻaleka koʻikoʻi , hiki i kāu kauka ke hāʻawi iā ʻoe i kahi inikini epinephrine hiki iā ʻoe ke mālama mau me ʻoe. Pono ʻoe e hāʻawi iā ʻoe iho i kēia inikini ke kāhea ʻoe i 911 (1990 ma Sri Lanka) i kahi pilikia.
• No ka angioedema allergic , hiki i kāu kauka ke kuhikuhi i nā antihistamines a i ʻole steroids . Hiki ke lawe ʻia kēia mau mea ma ke ʻano he pila, ma ke ʻano he wai (waha), a i ʻole hāʻawi ʻia ma ke ʻano intravenous.
• Inā loaʻa iā ʻoe kahi hopena lāʻau ʻaʻole allergic , e ʻimi kāu kauka i kahi koho kūpono no ka lāʻau e hoʻoulu ai i ka pehu. Mai ho'ōki i ka lawe ʻana i kāu lāʻau me ka ʻole o ke aʻo a kāu kauka.

ʻO nā lāʻau lapaʻau home e komo pū ana me ka hoʻopili ʻana i ka hau e hōʻemi i ka pehu, ka ʻauʻau ʻana i kahi ʻauʻau anuanu, a me ka hoʻopili ʻana i kahi lole anuanu a pulu i ka wahi pehu. Hiki i kēia ke hana maikaʻi no ka pehu kūloko, ka pehu ʻana ma nā lehelehe a pau, a i ʻole no nā maka pehu.

Inā loaʻa iā ʻoe ka angioedema hoʻoilina, idiopathic, a i ʻole ka C1 inhibitor deficiency i loaʻa , e kuhikuhi ʻia paha ʻoe i kahi loea. ʻO kekahi o nā lāʻau lapaʻau i hoʻohana ʻia e mālama ai a pale aku paha i ka angioedema hoʻoilina (HAE) e komo pū ana me:

• Mea hoʻopaʻa esterase C1 (recombinant) (Ruconest®)
• Mea hoʻopaʻa C1 (kanaka) (Berinert®, Cinryze®, Haegarda®)
• ʻEcallantide (Kalbitor®)
• ʻIcatibant (Firazyr®)
• ʻO Lanadelumab (Takhzyro®)
• ʻO Berotralstat (Orladeyo®)

Aia kekahi mau ala e pale aku ai i ka angioedema?

ʻAe, aia kekahi mau ala.

• Inā loaʻa iā ʻoe ka angioedema e pili ana i ka maʻi allergy , hiki iā ʻoe ke pale aku iā ia ma ka pale ʻana i nā meaʻai, nā lāʻau lapaʻau, a i ʻole nā ​​​​mea ʻē aʻe (nā mea hoʻoulu) e hoʻoulu ai i kahi hopena maʻi.
• Inā loaʻa iā ʻoe ka angioedema non-allergic i ka wā e lawe ana i nā lāʻau ACEI (ACE inhibitors) , pono ʻoe e kamaʻilio me kāu kauka e pili ana i ka hoʻololi ʻana i kahi lāʻau lapaʻau ʻē aʻe.

He aha ka mea e hiki i kekahi me ka angioedema ke manaʻo?

ʻAʻole lōʻihi ka hapa nui o nā hihia o ka angioedema. Hoʻopau pinepine lākou iā lākou iho. Eia nō naʻe, i nā hihia koʻikoʻi, pono ka lāʻau lapaʻau e mālama i ke ala ea e wehe.

Hiki i ka Angioedema ke make? He mea weliweli anei kēia?

No kekahi poʻe, hiki i ka angioedema allergic ke alakaʻi i kahi kūlana i kapa ʻia ʻo anaphylaxis - ka pehu nui o nā alaloa a me nā māmā. Hiki i kēia ke hoʻoweliweli i ke ola . Ke aʻo aku nei nā kauka i ka poʻe me kēia kūlana e lawe i ka epinephrine injectable (EpiPen®, Auvi-Q®, Adrenaclick® a me nā lama ʻē aʻe) e mālama i nā hopena allergic koʻikoʻi.

ʻOiai ke kumu, he pilikia olakino mau ka angioedema e hoʻopilikia ana i ke alaea. No laila, pono ka mālama koke ʻana. I kekahi manawa, pono paha kahi hana ʻoki i kapa ʻia ʻo tracheostomy (ka hana ʻana i kahi puka i loko o ka windpipe) e kōkua i ka hanu ʻana.

Inā loaʻa iaʻu ka angioedema, pehea e hiki ai iaʻu ke mālama iaʻu iho?

Inā loaʻa iā ʻoe ka angioedema, pono ʻoe e pale i nā mea hoʻoulu i ka maʻi allergy . Inā kuhikuhi kāu kauka i nā lāʻau lapaʻau e pale aku i nā hanana hou aʻe, e lawe iā lākou e like me ke kuhikuhi ʻana. Inā ua ʻōlelo ʻia ʻoe e lawe i ka epinephrine injectable , e hōʻoia e loaʻa mau iā ʻoe. E aʻo i kou ʻohana a me nā hoaaloha pehea e hoʻohana ai.

Āhea wau e ʻike ai i ke kauka?

Inā loaʻa iā ʻoe kahi maʻi alerika koʻikoʻi a hoʻopilikia ka pehu i kou ala hanu, e kāhea koke i ka 1990 (lawelawe ambulance ulia pōpilikia).

I nā hihia ʻoi aku ka liʻiliʻi o ke koʻikoʻi, inā hoʻomau ʻoe i ka angioedema, e ʻike i kāu kauka. Hiki iā lākou ke kūkākūkā i nā koho pale. ʻO nā koho lapaʻau ʻē aʻe e komo pū me nā antihistamines waha a me nā steroids. Idiopathic, paʻakikī ke mālamaUa hoʻohana kekahi mau kauka i kahi antibody monoclonal i kapa ʻia ʻo Omalizumab (Xolair®) no ka angioedema (idiopathic angioedema).

ʻO ka mea hope loa, nā mea nui e hoʻomanaʻo

Inā pehu kou mau maka, lehelehe, a lima paha, he ʻano ʻili paha ia i kapa ʻia ʻo angioedema. ʻOi aku ka maʻalahi o kēia inā loaʻa iā ʻoe nā maʻi allergies. E mālama i kahi moʻolelo o ka wā a me ka manawa e hana ai kēia, a e aʻo e pale i nā mea āu e maʻi ai. Inā ʻike ʻoe ua loaʻa i nā poʻe ʻē aʻe o kou ʻohana kēia mau hopena, e haʻi i kāu kauka. Hiki iā ia ke kuhikuhi i nā hoʻokolohua e ʻike ai inā holo ke ʻano i loko o kou ʻohana. Inā loaʻa iā ʻoe ka angioedema ma muli o kahi maʻi allergies, he mea nui loa ka mālama ʻana i kahi epinephrine injectable, no ka mea, hiki i ka pehu ʻana i kou mau ala ea ke hoʻōki i kou hanu ʻana. Mai hopohopo, akā he mea naʻauao ke makaʻala i kēia a lawe i nā hana e pono ai.

ʻAngioedema , pehu, nā maʻi ʻaleka, nā maʻi ʻili, ka mālama pilikia, epinephrine, urticaria