Pono anei mākou e ʻike e pili ana i nā hopena ʻaoʻao o nā lāʻau lapaʻau Ankylosing Spondylitis?

Inā loaʻa iā ʻoe ka ankylosing spondylitis, ʻike paha ʻoe i ke koʻikoʻi o ka hoʻoikaika kino me ka lāʻau lapaʻau a kāu kauka i kuhikuhi ai. Hiki i kēia mau lāʻau lapaʻau ke kōkua i ka hōʻemi ʻana i kou ʻeha a kōkua iā ʻoe e hoʻomanawanui i kou lā me ka maʻalahi. Eia nō naʻe, i kekahi manawa hiki i kēia mau lāʻau lapaʻau ke hana i nā hopena ʻaoʻao liʻiliʻi. Akā, mai hopohopo, ʻaʻole kēia ka hihia no nā kānaka a pau. ʻOkoʻa ka pane ʻana o ke kino o kēlā me kēia kanaka i nā lāʻau lapaʻau. No laila, he mea nui e ʻimi i ka lāʻau lapaʻau kūpono nāu, me nā hopena ʻaoʻao liʻiliʻi loa. I kēia lā, e kamaʻilio mākou e pili ana i kēia mau lāʻau lapaʻau a me kā lākou mau hopena ʻaoʻao.

Lāʻau lapaʻau laina mua: NSAIDs

ʻO kēia nā lāʻau ʻeha mua a nā kauka e kuhikuhi pinepine ai no ka poʻe me ka ankylosing spondylitis. Ua kapa ʻia kēia mau mea he mau lāʻau anti-inflammatory nonsteroidal, a i ʻole NSAID . Ua kamaʻāina paha ʻoe i kēia mau inoa: Ibuprofen, Naproxen, Indomethacin, Celecoxib, a pēlā aku. ʻO kēia nā lāʻau lapaʻau i hāʻule i loko o kēia māhele.

Hana nui kēia mau mea ma ka hōʻemi ʻana i ka mumū a me ka ʻeha i kou mau hono. Eia nō naʻe, hiki i kēia mau lāʻau lapaʻau ke hana i kekahi mau hopena ʻaoʻao ke lawe ʻia i nā dosis kiʻekiʻe no ka manawa lōʻihi.

Nā lāʻau lapaʻau hou: Biologics (IL-17 a me JAK Inhibitors)

Inā paʻakikī nā NSAID e kāohi i kāu mau hōʻailona, ​​​​​​e ʻōlelo hou aku paha kāu kauka i kahi papa kūikawā o nā lāʻau lapaʻau i kapa ʻia ʻo biologics. Hana kēia mau mea ma ke kuhikuhi ʻana i nā kemika kikoʻī i loko o ke kino e hoʻoulu ai i ka mumū a hoʻōki iā lākou mai ka hana ʻana.

Nā mea pale IL-17

ʻO Secukinumab (Cosentyx) lāua ʻo Ixekizumab (Taltz) ʻelua o kēia ʻano lāʻau. Hāʻawi ʻia lākou ma ke ʻano he inikini. ʻOiai he maikaʻi loa lākou, hiki iā lākou ke loaʻa kekahi mau hopena ʻaoʻao.

• ʻO ka maʻi mumū o ka ʻōpū (IBD): Hiki i kēia lāʻau lapaʻau ke hoʻoulu i ka hoʻomaka hou ʻana o IBD i kekahi poʻe a i ʻole e hoʻonui i nā hōʻailona inā loaʻa iā ʻoe.
• Nā maʻi: No ka mea, he hopena liʻiliʻi kēia mau lāʻau lapaʻau i ka ʻōnaehana pale o ke kino, hiki ke hoʻonui iki ʻia ka pilikia o ka loaʻa ʻana o nā maʻi maʻamau (e like me ka maʻi palū a me ke anu).
• Ka pilikia o ke kanesa: ʻOiai ua hōʻike nā hoʻokolohua hoʻokolohua i ka pilikia o ke kanesa ke hāʻawi ʻia i nā ʻiole, ʻaʻohe hōʻike maopopo o ka pilikia i nā kānaka. Mai hopohopo pono ʻole e pili ana i kēia, na kāu kauka e aʻo iā ʻoe ma kēia.

Nā mea pale JAK

ʻO Tofacitinib (Xeljanz) kahi ʻano lāʻau lapaʻau e hiki ke lawe ʻia ma ke ʻano he pila. Hana pū ia ma ka hōʻemi ʻana i ka mumū. ʻO kekahi o nā hopena ʻaoʻao e pili ana me ia :

• ʻEha poʻo
• Ka maʻi pākī
• Luhi
• Nā palpitations o ka puʻuwai
• Ka liʻiliʻi o ka pilikia o ka hōʻino ʻana o ke akepaʻa

Nā lāʻau lapaʻau i hoʻohana pinepine ʻole ʻia

I kekahi mau hihia, hiki ke hoʻohui ʻia nā lāʻau lapaʻau ʻē aʻe i kāu hoʻolālā lapaʻau.

Nā lāʻau lapaʻau steroid (Corticosteroids)

ʻAʻole i kuhikuhi pinepine ʻia kēia mau lāʻau no ka mālama lōʻihi o ka ankylosing spondylitis. Eia nō naʻe, inā nui loa ka ʻeha a me ka pehu ʻana, hiki i kāu kauka ke hāʻawi iā ʻoe i kahi inikini steroid i loko o ka hui pehu. ʻO ka hoʻohana lōʻihi ʻana i kēia mau lāʻau lapaʻau hiki ke hana i nā hopena ʻaoʻao he nui. No laila, hoʻohana wale ʻia lākou i ka wā pōkole, inā pono. ʻO kekahi o nā hopena ʻaoʻao:

• Hoʻonui ʻia ka makemake a me ka piʻi ʻana o ke kaumaha
• Pehu maka, ʻākena
• Ka ulu ʻana o ka lauoho kino
• ʻEha maʻalahi
• ʻO ka maʻi diabetes (diabetes) a i ʻole ka hoʻonui ʻia ʻana inā loaʻa
• Ke koko kiʻekiʻe
• Nā maʻi cataract a i ʻole glaucoma
• ʻOsteoporosis

Nā lāʻau lapaʻau ʻeha hui ʻē aʻe (Sulfasalazine a me Methotrexate)

Inā, ma waho aʻe o kou ʻeha hope, loaʻa iā ʻoe ka ʻeha ma nā hono ʻē aʻe, e like me kou mau poʻohiwi, nā lima, a me nā wāwae, hiki i kāu kauka ke ʻōlelo i kēia mau lāʻau lapaʻau.

Sulfasalazine (Azulfidine): He pila kēia . He mea kākaʻikahi nā hopena ʻaoʻao , akā hiki i kekahi poʻe ke loaʻa i ke kuni, ka nausea, ka ʻulaʻula o ka ʻili, a me ke poʻo.

Methotrexate: Hiki ke lawe ʻia kēia ma ke ʻano he pila a i ʻole he inikini. Ke lawe nei i kēia lāʻau lapaʻau, hiki i kāu kauka ke ʻōlelo aku e lawe i ka waikawa folic vitamin e hōʻemi i nā hopena ʻaoʻao . Hiki i nā hopena ʻaoʻao ke komo pū me ka nausea, nā ʻeha waha, a me ka luhi.

He aha e hana ai inā loaʻa nā hopena ʻaoʻao?

ʻO kēia ka ʻāpana koʻikoʻi loa. Inā loaʻa iā ʻoe kekahi mau loli a ʻoluʻolu ʻole paha i kou kino ma muli o ka lāʻau āu e lawe nei, ʻo ka mea mua a maikaʻi loa e hana ai, ʻo ia ke haʻi aku i kāu kauka.

Ke haʻi aku ʻoe i kāu kauka e pili ana i kēia, hiki paha iā ia:

• E hōʻemi i kāu nui o ka lāʻau lapaʻau.
• E hoʻololi i kahi lāʻau lapaʻau ʻē aʻe e kūpono iā ʻoe.
• E hāʻawi i kekahi lāʻau lapaʻau ʻē aʻe e kāohi ai i ka hopena ʻaoʻao.

Eia kekahi laʻana, inā loaʻa iā ʻoe ka ʻeha ʻōpū mai kahi NSAID, hiki i kāu kauka ke kuhikuhi i kahi lāʻau lapaʻau ʻē aʻe e pale aku i kou ʻōpū i ka manawa like. No laila, mai makaʻu e kamaʻilio me kāu kauka e pili ana i kēia mau mea āpau. I ka hui pū ʻana, hiki iā ʻoe a me kāu kauka ke loaʻa i ka hoʻolālā lapaʻau e kūpono loa iā ʻoe a loaʻa nā hopena ʻaoʻao liʻiliʻi loa.