Ua lohe paha ʻoe i ko kākou mau makuahine, nā makuakāne, nā kupuna wahine, a me nā kupuna kāne e ʻōlelo ana, "Auē, ua nāwaliwali koʻu kino i kēia manawa," a "Ua palupalu koʻu mau iwi." ʻOiaʻiʻo, i ko kākou ʻelemakule ʻana, emi iho ka ikaika o ko kākou kino, a emi mālie ka ikaika o ko kākou mau iwi. I kekahi manawa, i ka wā e koʻikoʻi ai kēia ʻano, ʻoiai ka hāʻule iki ʻana a i ʻole ke ala ʻana mai kahi moe hiki ke alakaʻi i kahi pilikia nui o ka haki ʻana o ka lima a i ʻole ka wāwae. ʻO kēia ʻano e nāwaliwali ai nā iwi a palupalu hoʻi ua kapa ʻia ʻo osteoporosis . No laila, i kēia lā e kamaʻilio mākou e pili ana i kahi papa lāʻau koʻikoʻi loa a nā kauka e hoʻohana ai e kāohi i kēia ʻano nāwaliwali o ka iwi.
I ka ʻōlelo maʻalahi, he aha kēia mau bisphosphonates?
ʻO nā Bisphosphonates kahi papa o nā lāʻau lapaʻau i hoʻohana ʻia e mālama i nā kūlana e like me ka osteoporosis e hōʻemi ana i ka nui o ka iwi a me ka ikaika. ʻO ke ʻano kēia ʻaʻole hoʻokahi lāʻau me kēia inoa, akā he hui pū ʻana o kekahi mau lāʻau lapaʻau. Ma waho aʻe o ka osteoporosis, kuhikuhi pū nā kauka i kēia lāʻau lapaʻau no kekahi mau hihia o nā pae calcium koko kiʻekiʻe loa (hypercalcemia).
E nānā kākou i nā ʻano lāʻau lapaʻau nui ma lalo o kēia māhele. Loaʻa kēia i ʻelua ʻano nui. ʻO kekahi he waha (nā pila i lawe ʻia ma ka waha), a ʻo kekahi he intravenous (IV) (wai i hāʻawi ʻia i loko o kahi aʻa).
| Pehea e hāʻawi ai i ka lāʻau lapaʻau | Nā hiʻohiʻona o nā lāʻau lapaʻau (i hoʻohana pinepine ʻia ma Sri Lanka) |
|---|---|
| Nā Bisphosphonates Waha | ʻAlendronate, Risedronate, ʻIbandronate |
| Nā wai intravenous (IV Bisphosphonates) | ʻAkika Zoledronic, Pamidronate |
Pehea ka hopena o kēia lāʻau lapaʻau i ke kino?
I mea e maopopo ai i kēia, pono mua kākou e hoʻomaopopo iki e pili ana i ke ʻano o ka hana ʻana o ko kākou mau iwi. E noʻonoʻo i ko kākou mau iwi me he hale lā e hoʻoponopono mau ʻia nei. Hoʻopau maoli ko kākou kino a wehe i ka iwi kahiko a nāwaliwali. Ua kapa ʻia kēia kaʻina hana he bone resorption.I ka manawa like, hoʻokumu ʻia ka iwi hou a ikaika aʻe ma nā wahi i wehe ʻia ai. Inā kaulike kēia mau kaʻina hana ʻelua, e mau ana ka ikaika o ko kākou mau iwi.
Eia nō naʻe, i ko kākou ʻelemakule ʻana, ʻoiai ma hope o ka menopause i nā wahine, nalowale kēia kaulike. ʻO ka mea e hana ʻia ana, ʻoi aku ka wikiwiki o ka wāwahi ʻia ʻana o ka iwi kahiko ma mua o ka hoʻokumu ʻia ʻana o ka iwi hou. ʻO ka hopena, e lilo mālie ana nā iwi i mea lahilahi, ʻoi aku ka porous, a nāwaliwali.
No laila, ʻo ka hana a kēia mau bisphosphonates, ʻo ia ke kāohi nui a hoʻemi i ka wikiwiki o ka resorption iwi. A laila, no ka mea, ua ikaika ka iwi kahiko i ka wā e hana ʻia ai ka iwi hou, piʻi ka nui o ka mānoanoa a me ka ikaika o nā iwi. I ka ʻōlelo maʻalahi, hoʻōki lākou i ka nalowale o ka iwi.
He aha nā kūlana e hoʻohana ʻia ai nā bisphosphonates?
ʻO ka mea nui, paipai nā kauka i kēia lāʻau lapaʻau no nā kūlana penei:
- ʻO ka Osteoporosis kahi maʻi e kū mai ana i nā wahine ma hope o ka menopause.
- ʻO ka osteoporosis i nā kāne.
- No ka pale ʻana i ka hiki ʻana mai o ka osteoporosis.
- ʻO ka Osteoporosis i hoʻokumu ʻia e ka hoʻohana mau ʻana i nā lāʻau lapaʻau e like me nā steroids (glucocorticoids).
- ʻO ka maʻi iwi o Paget kahi maʻi e ulu kūpono ʻole ai nā iwi.
- Kaohi ʻana i nā pilikia e kū mai ana me kekahi mau ʻano maʻi kanesa (e like me Multiple Myeloma) a me ka wā e laha ai nā hunaola kanesa i nā iwi (Bone Metastasis).
- No ke kāohi ʻana i ka hypercalcemia pili i ka maʻi kanesa (hoʻonui ʻia ka nui o ka calcium i loko o ke koko ma muli o ke kanesa).
Pehea e hoʻohana ai au i kēia lāʻau lapaʻau? He mea nui loa kēia!
He mea nui e hahai pololei i kēia mau kuhikuhi i mea e loaʻa ai ka pono piha o ka lāʻau lapaʻau a hōʻemi i nā hopena ʻaoʻao.
Nā lāʻau lapaʻau waha
He kikoʻī loa ke ʻano o ka lawe ʻana i kēia mau pila. Pono ʻoe e hahai pono i nā kuhikuhi a ke kauka.
- Pono e lawe ʻia ka pila i ke kakahiaka, ma mua o ka ʻai ʻana a inu ʻana paha i kekahi mea (me ka ʻōpū ʻole) .
- Pono e lawe wale ʻia ka pila me ke aniani piha o ka wai (wai maʻemaʻe) . Kapu loa ka lawe ʻana i kēia lāʻau lapaʻau me nā mea e like me ke kī, ke kope, ka waiū, a i ʻole nā mea inu hua.
- ʻO ka mea nui loa: Ma hope o ka lawe ʻana i ka lāʻau lapaʻau, pono ʻoe e noho a kū paha no 30 a 60 mau minuke ma ka liʻiliʻi . Mai hilinaʻi, moe i lalo, a hiamoe paha no kekahi kumu.
- ʻO ke kumu o kēia, hiki i kēia lāʻau lapaʻau ke hōʻino i ka esophagus. Hoʻopau ʻia kēlā pilikia ke kū ʻoe i luna no ka mea hele koke ka lāʻau lapaʻau i loko o ka ʻōpū.
- ʻAʻole ia he manaʻo maikaʻi e ʻai a inu paha i kekahi mea ʻē aʻe i loko o kēia wā 30-60 mau minuke. Ma hope o ka pau ʻana o kēlā manawa, hiki iā ʻoe ke ʻaina kakahiaka e like me ka mea maʻamau.
Nā lāʻau lapaʻau IV
ʻAʻole hiki iā ʻoe ke hana i kēia ma ka home. Hāʻawi ʻia kēia lāʻau lapaʻau ma kahi haukapila a i ʻole ke keʻena lapaʻau. Ma muli o kou kūlana, hāʻawi pinepine ʻia kēia inikini (infusion) i hoʻokahi manawa i ka makahiki a i ʻole i kēlā me kēia mau mahina.
ʻOiai e lawe ana i kēia lāʻau lapaʻau, e ʻōlelo pinepine kāu kauka e ʻai ʻoe i nā meaʻai waiwai i ka calcium (waiū, yogurt, tīhi, iʻa liʻiliʻi) a lawe i kahi mea hoʻopihapiha wikamina D , no ka mea, he mea nui nā mea ʻelua no nā iwi ikaika.
He aha nā hopena ʻaoʻao o nā bisphosphonates?
E like me nā lāʻau lapaʻau āpau, aia paha kekahi mau hopena ʻaoʻao. Akā, mai hopohopo, ʻo ka hapa nui o lākou he mea liʻiliʻi wale nō.
| ʻAno lāʻau lapaʻau | Nā hopena ʻaoʻao hiki ke loaʻa |
|---|---|
| Lāʻau lapaʻau waha | Nā pilikia ʻōpū e like me ka ʻeha puʻuwai, GERD, esophagitis, ʻeha ʻōpū, a me nā ʻōpala. (Hiki ke pale nui ʻia kēia mau mea ma ka hahai ʻana i ke ala kūpono e lawe ai i kāu lāʻau lapaʻau.) |
| Lāʻau lapaʻau intravenous (IV) | ʻO nā hōʻailona like me ke anu a i ʻole ka maʻi palū, e like me ke kuni, ka ʻeha kino, ka ʻeha poʻo, a me ka ʻeha o nā hono a me nā ʻiʻo, hiki ke ʻike ʻia no hoʻokahi a ʻelua paha lā ma hope o ka lawe ʻana i ka lāʻau. Nalo pinepine kēia mau mea i loko o kekahi mau lā. |
Nā hopena ʻaoʻao i kakaikahi loa akā pono e makaʻala
ʻOiai he mea kakaikahi loa kēia, he mea nui e ʻike iā lākou.
- ʻO ka Osteonecrosis o ka ʻāwae: He liʻiliʻi loa kēia pilikia, ʻoiai ma hope o ke ʻoki ʻana e like me ka unuhi ʻana o ka niho. No laila, inā ʻoe e lawe ana i kēia lāʻau lapaʻau, e haʻi aku i kāu kauka niho i kēlā me kēia manawa āu e ʻike ai iā ia.
- Nā haki femur atypical: He mea laha ʻole kēia i waena o ka poʻe e lawe ana i kēia lāʻau lapaʻau no ka manawa lōʻihi (ʻoi aku ma mua o 3-5 mau makahiki).
- Nā pilikia maka: Hiki ke loaʻa nā mumū (uveitis, scleritis) o nā ʻāpana like ʻole o ka maka.
ʻO ka mea nui loa, ʻo ia ka pilikia o ka haki ʻana o ka iwi ma muli o ka osteoporosis inā ʻaʻole ʻoe e lawe i kēia lāʻau lapaʻau he tausani manawa ʻoi aku ka nui ma mua o ka pilikia liʻiliʻi loa o kēia mau hopena ʻaoʻao. No laila, he mea nui loa e hahai i nā ʻōlelo a kāu kauka.
Āhea ʻoe e makemake ai e ʻike hou i ke kauka?
Inā ʻoe e lawe ana i kēia lāʻau lapaʻau, he mea nui e ʻike i kāu kauka i nā manawa maʻamau e nānā inā e hana ana ka lāʻau lapaʻau a inā he mau hopena ʻaoʻao. Hiki ke kuhikuhi ʻia ʻoe i kahi loea iwi (Endocrinologist a Rheumatologist paha).
Hiki paha i kāu kauka ke ʻōlelo aku i kahi scan DXA e ʻike i ke ʻano o ka mānoanoa o kou mau iwi.
Hoʻomaopopo Kūikawā: Inā ʻoe e hoʻohana nei i kēia lāʻau lapaʻau no nā makahiki ʻekolu a ʻoi a loaʻa iā ʻoe ka ʻeha hou ma kou ʻūhā a i ʻole ka ʻūhā, mai hoʻowahāwahā iā ia a e hoʻomaopopo koke i kāu kauka.
Leka Lawe-Home
- He lāʻau lapaʻau maikaʻi loa nā Bisphosphonates e kōkua ai i ka hoʻoikaika ʻana i nā iwi i nāwaliwali ʻia e ka osteoporosis.
- Hana kēia mau lāʻau lapaʻau ma ka hoʻolohi ʻana i ka nui o ka pohō o ka iwi.
- I ka wā e lawe ai i ka lāʻau lapaʻau waha, he mea nui e inu ia ma ka ʻōpū ʻole, me ka wai wale nō, a e kū a noho paha no 30-60 mau minuke ma hope o ka lawe ʻana i ka lāʻau.
- ʻOiai hiki ke loaʻa nā hopena ʻaoʻao liʻiliʻi, he kakaikahi loa nā hopena ʻaoʻao koʻikoʻi. ʻOi aku ka nui o nā pono o ka lāʻau lapaʻau ma mua o nā pilikia.
- Inā he mau nīnau kāu, hopohopo, a kānalua paha e pili ana i kēia lāʻau lapaʻau, e kamaʻilio ākea me kāu kauka e pili ana. Mai ho'ōki i ka lawe ʻana i kāu lāʻau lapaʻau me ka ʻole o ke aʻo lapaʻau.
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