Loaʻa iā ʻoe nā 'Blast Cells' i kāu Hōʻike Koko? E kamaʻilio maʻalahi kākou e pili ana i kēia (Blast Cells)

Ua ʻike anei ʻoe i ka huaʻōlelo 'Blasts' i ka nānā ʻana i kāu hōʻike koko? He mea maʻamau ke manaʻo iki i ka makaʻu a me ka hoihoi ke ʻike ʻoe. No ka mea, ʻōlelo nui kēia huaʻōlelo maʻamau ʻole e pili ana i ko kākou olakino. No laila i kēia lā, e kamaʻilio kākou e pili ana i ke ʻano o kēia mau Blast Cells, pehea lākou e koʻikoʻi ai i ko kākou kino, a me ka mea e hōʻike ai ko lākou helu hoʻonui. Mai hopohopo, e hoʻomaopopo maʻalahi kākou i kēia.

He aha nā Blast Cells ma nā huaʻōlelo maʻalahi?

I ka ʻōlelo maʻalahi, ʻo nā cell blast he "baby cells" a i ʻole nā ​​​​cell immature. E like me ka pēpē. ʻO kēia nā cell e oʻo ma hope, ʻo ia hoʻi, e ulu aʻe, a lilo i nā ʻano cell like ʻole e pono ai ko mākou kino. Akā inā ʻōlelo kāu hōʻike lab i nā "blasts," ʻo ia paha ke kuhikuhi nei i nā cell koko immature . Nānā nā hematologists a me nā oncologists i ka helu o kēia mau cell blast i loko o kou koko e hana i nā hopena e pili ana i nā maʻi like ʻole e pili ana i ke koko.

He aha ka ʻokoʻa ma waena o nā Stem Cells a me nā Blast Cells?

He mea kēia e huikau ai nā kānaka he nui. E noʻonoʻo i nā cell kumu ma ke ʻano he "cell kumu" e hoʻomaka ai nā mea āpau. Ua like ia me kahi puʻu lepo. Hiki iā mākou ke hana i kekahi mea mai kēlā puʻu lepo, e like me ka ipu hao, ke kīʻaha, kekahi mea. Pēlā ke ʻano o nā cell kumu. Hiki iā lākou ke lilo i kekahi ʻano cell.

ʻO nā cell blast ka hana aʻe i ka hoʻomohala ʻana o kēia mau cell kumu. I kēia manawa ua hoʻomaka mākou e hana i ipuhao mai kēlā puʻu lepo, a ke hoʻomaka nei ke ʻano. I kēia manawa, ʻaʻole hiki iā mākou ke hana hou i loko o ke kīʻaha. No laila, ʻo kahi cell blast he cell i hoʻomaka e hele i kahi huakaʻi kikoʻī. ʻO ia hoʻi, ua hoʻoholo ʻo ia e lilo i cell koko ʻulaʻula, cell koko keʻokeʻo, a i ʻole platelet. ʻO ia ke kumu i kapa ʻia ai nā cell blast he "precursor cells."

ʻO ka hana a nā pūnaewele pahū i loko o ko mākou kino a me kahi i hana ʻia ai lākou

ʻO nā cell blast kekahi kahua wale nō o ke kaʻina hana o ke koko i loko o ko mākou kino. Kāhea mākou i kēia kaʻina hana koko ʻo 'Hematopoiesis'. Hana nui kēia i loko o ko mākou iwi iwi . Ua like ka iwi iwi me ka hale hana koko o ko mākou kino.

I loko o kēia hale hana, ʻo ke kelepona kumu nui i kapa ʻia ʻo `Hematopoietic Stem Cell (HSC)` e hoʻāla ana i ʻelua ʻano nui o nā kelepona pahū:

• Myeloblast: Ma hope aku, ulu kēia mau pūnaewele pahū e lilo i mau hunaola koko ʻulaʻula (nāna e lawe i ka oxygen), kekahi mau ʻano hunaola koko keʻokeʻo (granulocytes - nā mea e hakakā nei i ka maʻi), a me nā platelets (nāna e kōkua i ke kāpili ʻana o ke koko).
• Lymphoblast: Hoʻomohala ʻia kēia mau pūnaewele pahū i loko o nā lymphocytes, kahi ʻano koʻikoʻi o ke koko koko keʻokeʻo (he ʻāpana koʻikoʻi o ka ʻōnaehana pale).

He aha ke kumu o ka hoʻonui ʻia ʻana o nā cell blast?

Pono nā pūnaewele pahū e emi iho ma mua o 5% o ka huina o nā pūnaewele i loko o ka iwi iwi o ke kanaka olakino. Eia kekahi, ʻaʻohe pūnaewele pahū i loko o ke koko o ke kanaka olakino.

Inā he nui ka nui o nā pūnaewele pahū i loko o kou iwi iwi a i ʻole ke koko, he hōʻailona paha ia o kahi maʻi ʻaʻai koko e like me ka leukemia, ʻoiai inā he ʻano ʻē kēia mau pūnaewele ke nānā ʻia ma lalo o kahi microscope.

Hiki iā ʻoe ke loaʻa kahi ʻike maikaʻi aʻe o kēia mai ka papa ma lalo nei.

Hiki i nā pūnaewele pahū ke hoʻonui me ka ʻole o ka hoʻoulu ʻana i ka maʻi kanesa?

ʻAe, hiki iā ʻoe. He mea nui loa kēia. ʻO ka hoʻonui ʻia ʻana o nā cell blast ʻaʻole ia he manaʻo mau no ka maʻi kanesa. Hiki i kekahi mau kūlana a me nā lāʻau lapaʻau ʻaʻole kanesa ke hoʻoulu i nā cell blast e komo i loko o ke koko no kekahi manawa.

• Nā Maʻi Koʻikoʻi: Ke loaʻa i ke kino kahi maʻi koʻikoʻi e like me ka 'Sepsis', hoʻomaka ko mākou kino e hana i nā nui o nā hunaola koko keʻokeʻo e hakakā i ka maʻi. I kēia manawa, hiki i kekahi mau hunaola pahū ʻōpiopio ke komo i loko o ke koko mai ka iwi iwi.
• Lapaʻau G-CSF: Ke hana ʻia nei nā lāʻau lapaʻau maʻi kanesa e like me ka chemotherapy, emi iho nā hunaola koko keʻokeʻo. I kēlā manawa, hāʻawi ʻia kahi inikini i kapa ʻia ʻo 'Granulocyte-colony stimulating factor (G-CSF)' e hoʻoulu i ka hana ʻana o nā hunaola koko keʻokeʻo. Hiki i kēia inikini ke hoʻonui i ka helu o nā hunaola pahū i loko o ke koko no kekahi manawa.
• Nā hoʻoili pūnaewele kumu: Ma hope o nā hoʻoili pūnaewele kumu no kekahi kūlana, hiki ke hoʻonui ʻia ka helu o nā pūnaewele pahū i ke kaʻina hana o ke kūkulu ʻana i ke koko hou.

Akā ʻo ka mea nui , ʻo ia ka nānā ʻana o kēia mau pūnaewele pahū ʻaʻole i loaʻa i ka maʻi kanesa i ke olakino ma lalo o ka microscope. Hiki iā lākou ke hana i kā lākou hana ke ulu lākou. I loko o ke kanesa, ʻike mākou i nā pūnaewele pahū ʻano ʻē a ʻano ʻē.

Pehea ʻoe e nānā ai i ka pae o nā cell pahū?

Hoʻohana nā kauka i kekahi mau hoʻokolohua nui e aʻo ai e pili ana i nā pūnaewele pahū.

• ʻO ka hoʻopili koko peripheral (PBS):ʻO kēia ke kāpili ʻana i kahi kulu o kou koko ma luna o kahi slide aniani a nānā iā ia ma lalo o kahi microscope. Hiki iā ʻoe ke loaʻa kahi manaʻo maʻamau inā he mau cell blast i loko o ke koko, pehea ko lākou ʻano, a me ka pakeneka.
• Nā hoʻāʻo ʻana i ka iwi iwi: ʻO kēia ke ala maikaʻi loa e loaʻa ai ka ʻike pololei a piha loa e pili ana i nā cell blast. ʻO kahi biopsy iwi iwi a i ʻole ka aspiration e pili ana i ka lawe ʻana i kahi nila liʻiliʻi mai kahi iwi nui, e like me ka iwi ʻūhā, a lawe i kahi laʻana o ka iwi iwi. A laila hoʻāʻo ʻia i loko o kahi lab e hoʻoholo ai i ka pakeneka o nā cell blast a me ko lākou ʻano pololei.
• Helu Koko Piha (CBC): Nānā kēia i kāu mau helu koko ʻulaʻula, nā huna koko keʻokeʻo, a me nā helu platelet. Ke piʻi aʻe nā huna koko pahū, hiki ke emi ka helu o kēia mau huna koko olakino.

No laila, mai hopohopo inā ʻike ʻoe i nā 'pahū' ma kāu hōʻike. Hiki iā ia ke lilo i hōʻailona o kahi mea koʻikoʻi, a i kekahi manawa hiki ke lilo i kūlana manawa pōkole. ʻO ka mea nui loa, ʻo ke kamaʻilio ʻana me kāu kauka e pili ana i ia mea a hahai i kāna ʻōlelo aʻo. E kuhikuhi ʻo ia iā ʻoe i kahi loea koko inā pono.