Ua ʻike anei ʻoe a i ʻole kekahi āu i ʻike ai i ka pehu koke ʻana o nā ʻāpana o kou kino, ʻoiai kou maka, lehelehe, alelo, a i ʻole nā lālā, me ka ʻole o ka ʻeha? I kekahi manawa hiki i kēia pehu ke alakaʻi i ka paʻakikī o ka hanu ʻana. Kāhea mākou i kēia maʻi ʻo Angioedema. I kēia lā ke kamaʻilio nei mākou e pili ana i kahi lāʻau pale kūikawā i hāʻawi ʻia e pale aku i nā hoʻouka pehu e kū mai ana i kēia maʻi. Ua kapa ʻia ʻo ia ʻo C1 Inhibitor, Human vaccine.
I ka ʻōlelo maʻalahi, he aha kēia lāʻau pale C1 Inhibitor?
ʻO ka C1 Inhibitor kahi protein i hana maoli ʻia i loko o ko kākou kino āpau. Hoʻomalu ia i kekahi o nā kaʻina hana o kā kākou ʻōnaehana pale. Eia nō naʻe, no kekahi poʻe, ma muli o nā kumu genetic (ua kapa ʻia kēia ʻo Hereditary Angioedema) a i ʻole nā kumu ʻē aʻe, ʻaʻole i hana ʻia kēia protein C1 Inhibitor i loko o ke kino i ka nui kūpono. ʻO ia ka manawa e puka koke mai ai ka pehu e like me ka mea i ʻōlelo ʻia ma mua.
No laila, ʻo ka hana a kēia lāʻau pale, ʻo ia ka hāʻawi ʻana i ke kino i ka protein C1 Inhibitor i nele. Ua kapa ʻia kēia lāʻau pale ʻo 'Human' no ka mea ua hoʻomaʻemaʻe ʻia mai ka ʻāpana plasma o ke koko kanaka a hana ʻia ma hope o kahi hana kūikawā. Hiki ke loaʻa kēia lāʻau lapaʻau ma ka mākeke ma lalo o nā inoa inoa e like me Cinryze a i ʻole HAEGARDA.
ʻO ka mea nui loa, hoʻohana ʻia kēia lāʻau lapaʻau e pale i nā hoʻouka ʻana o ka angioedema.
Nā mea āu e haʻi aku ai i kāu kauka ma mua o ka lawe ʻana i kēia lāʻau lapaʻau
Ma mua o ka hāʻawi ʻana iā ʻoe i kēia lāʻau lapaʻau, pono i kāu kauka ke ʻike i kou mōʻaukala olakino piha. E hōʻoia e haʻi iā lākou inā loaʻa iā ʻoe kekahi o kēia mau kūlana:
- Nā maʻi ʻaʻai koko: Inā ua loaʻa iā ʻoe kahi maʻi ʻaʻai koko ma mua, e like me ke koko i loko o kahi aʻa koko ma ka wāwae (DVT - Deep Vein Thrombosis) a i ʻole ka hahau ʻana.
- Nā maʻi ʻaleka: Inā he maʻi ʻaleka kou i ka lāʻau pale C1 Inhibitor a i ʻole kekahi lāʻau lapaʻau ʻē aʻe, meaʻai, a mea hoʻomalu paha.
- Hāpai keiki: Inā hāpai ʻoe, e hoʻāʻo ana e hāpai, a hānai waiū paha.
Ma muli o kēia ʻike, e hoʻoholo kāu kauka inā kūpono kēia lāʻau lapaʻau iā ʻoe a pehea e hāʻawi ai.
Pehea e hoʻohana ai i ka lāʻau lapaʻau?
Hāʻawi ʻia kēia lāʻau lapaʻau ma nā ʻano ʻelua.
1. Hoʻokomo ʻana i loko o kahi aʻa: He ʻano hana no ka hāʻawi ʻana i kahi hopena, e like me ka saline, i loko o kahi aʻa.
2. Inikini ma lalo o ka ʻili: He inikini liʻiliʻi i hāʻawi ʻia ma lalo o ka ʻili.
ʻO ka maʻamau, hāʻawi ʻia kēia lāʻau lapaʻau iā ʻoe e kekahi loea mālama ola ma kahi haukapila a i ʻole ke keʻena lapaʻau. Eia nō naʻe, i kekahi mau hihia, pono paha ʻoe e lawe i kēia lāʻau lapaʻau ma ka home. I kēia hihia, e hāʻawi ʻia ʻoe i ke aʻo kūpono no ka hoʻomākaukau ʻana i ka lāʻau lapaʻau a pehea e hoʻokomo pololei ai . He mea nui loa ka lawe ʻana i ka lāʻau lapaʻau i ka manawa kūpono a me ka nui kūpono, e like me ka ʻōlelo a kāu kauka iā ʻoe.
Inā ʻoe e hoʻohana ana ia mea ma ka home, e noʻonoʻo i kēia.
Inā ʻoe e hoʻohana i nā nila a me nā syringe ma ka home, mai hoʻolei iā lākou i loko o ka ʻōpala ma hope o ka hoʻohana ʻana. E hoʻohana i kahi pahu ʻoi. Inā ʻaʻohe āu, e nīnau i kāu kauka pehea e loaʻa ai. He mea nui kēia no kou palekana, no kou ʻohana, a me ke kaiapuni.
Nā hopena ʻaoʻao hiki ke loaʻa o kēia lāʻau lapaʻau
E like me nā lāʻau lapaʻau āpau, hiki i kēia ke loaʻa kekahi mau hopena ʻaoʻao. Akā, ʻaʻole i loaʻa i nā kānaka a pau. E hoʻokaʻawale kākou i kēia mau hopena ʻaoʻao i ʻelua mau ʻano.
| Nā hopena ʻaoʻao o ka lāʻau pale C1 Inhibitor | |
|---|---|
| Nā hopena ʻaoʻao koʻikoʻi e pono e hōʻike koke ʻia i kāu kauka a i ʻole ETU | |
| Nā maʻi ʻaleʻale koʻikoʻi | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, lehelehe a i ʻole ke alelo, paʻakikī ke hanu. |
| Nā hōʻailona o nā ʻōpū koko | ʻEha, pehu a me ka mehana i ka wāwae (DVT), paʻakikī ka hanu ʻana, ʻeha ka umauma. |
| Nā Hōʻailona o ka Stroke | Ka maneʻo koke a nāwaliwali paha ma ka maka, ka lima, a i ʻole ka wāwae, ka huikau, ka paʻakikī i ka ʻōlelo ʻana a i ʻole ka hoʻomaopopo ʻana, ka paʻakikī i ka hele wāwae, ka poniuniu, ka nalowale o ke kaulike. |
| Nā hōʻailona koʻikoʻi ʻē aʻe | ʻEha poʻo nui, loli ka ʻike. |
| Nā hopena ʻaoʻao ʻaʻole i koʻikoʻi pinepine, akā pono e hōʻike ʻia i ke kauka inā hoʻomau lākou | |
| ʻEha poʻo | He hopena ʻaoʻao maʻamau kēia. |
Inā loaʻa iā ʻoe kekahi mau hōʻailona ʻē aʻe i ʻōlelo ʻole ʻia ma kēia papa inoa, e ʻoluʻolu e hoʻomaopopo i kāu kauka e pili ana iā lākou.
Kekahi mau mea ʻē aʻe e noʻonoʻo ai
- Ka nui loa o ka lāʻau lapaʻau: Inā manaʻo ʻoe ua lawe nui ʻoe i kekahi lāʻau lapaʻau, e kāhea koke aku i ke Kikowaena ʻIke Lāʻau Lapaʻau Lahui ma ka Halemai Lahui ʻo Colombo , a i ʻole e hele i ka Emergency Treatment Unit (ETU) o ka haukapila kokoke loa.
- Inā ʻoe e poina i kahi lāʻau lapaʻau: Inā ʻoe e poina i kahi lāʻau lapaʻau, e lawe koke iā ia i kou hoʻomanaʻo ʻana. Eia nō naʻe, inā kokoke ka manawa no kāu lāʻau lapaʻau aʻe, e kāpae i ka lāʻau lapaʻau i poina a lawe i kāu lāʻau lapaʻau aʻe i ka manawa i hoʻonohonoho ʻia. Mai lawe i ʻelua mau lāʻau lapaʻau i ka manawa hoʻokahi.
- Hana ʻia mai ke koko kanaka: E like me ka mea i ʻōlelo ʻia ma mua, hana ʻia kēia lāʻau lapaʻau mai ke koko kanaka. No laila, he liʻiliʻi loa ka pilikia o ka hoʻoili ʻana i nā maʻi, akā ʻaʻole ʻole. Eia naʻe, hana ʻia kēia lāʻau lapaʻau ma hope o nā kaʻina hana hoʻomaʻemaʻe a me ka hoʻāʻo ʻana. A hiki i kēia manawa, ʻaʻohe maʻi i hōʻike ʻia. E kamaʻilio me kāu kauka e pili ana i nā nīnau āu e pili ana i kēia.
- Mai kaʻana like i ka lāʻau lapaʻau me nā poʻe ʻē aʻe: Ua kuhikuhi ʻia kēia lāʻau lapaʻau nou wale nō. Mai kaʻana like me nā poʻe ʻē aʻe.
He mea nui hoʻi e hoʻomaopopo i kāu kauka inā ʻaʻole hoʻomaikaʻi kāu mau hōʻailona, a inā e ʻoi aku ka ʻino.
Leka Lawe-Home
- He lāʻau pale kūikawā ʻo C1 Inhibitor i hāʻawi ʻia e pale aku i ka pehu koke i hoʻokumu ʻia e ka Angioedema.
- Ma mua o ka lawe ʻana i kēia lāʻau lapaʻau, e haʻi i kāu kauka e pili ana i kāu ʻike olakino āpau, ʻoiai nā maʻi ʻaʻai koko a me nā maʻi allergies.
- I ka wā e hoʻohana ai i ka lāʻau lapaʻau, e makaʻala i nā hopena ʻaoʻao koʻikoʻi (ʻoi aku hoʻi nā hōʻailona o ke koko ʻana a i ʻole ka hahau ʻana). Inā ʻike ʻoe i kekahi o kēia mau mea, e ʻimi koke i ke kōkua lapaʻau.
- E kamaʻilio ākea me kāu kauka e pili ana i nā nīnau a hopohopo paha āu e pili ana i kēia lāʻau lapaʻau. Mai makaʻu.
- Inā ʻoe e hoʻohana i nā syringe ma ka home, e hoʻolei pono iā lākou me ka palekana.
👩🏽⚕️ Nā nīnau hou aku (FAQs)
💬 He aha ka mea e hoʻohana ʻia ai nā papa Difenoxin a me Atropine / Motofen?
ʻAʻole kēia he lāʻau lapaʻau hiki iā ʻoe ke kūʻai wale mai kahi hale kūʻai lāʻau lapaʻau! He hui pū ʻana kēia o nā lāʻau ikaika loa no kahi papa o nā lāʻau lapaʻau (Opioid antidiarrheal) a nā kauka e kuhikuhi ai e hoʻōki koke i ka maʻi diarrhea koʻikoʻi a i ʻole ka luaʻi ʻana i hiki ʻole ke hoʻomanawanui a hoʻomau a like me ka wai!
💬 Ke hiki mai ka maʻi kahe nui, pehea e hiki ai i kēia pila (Motofen) ke hoʻōki koke i ka maʻi kahe?
Ke neʻe kou ʻōpū, neʻe wikiwiki nā ʻōpū a hoʻokuke i ka ʻōpala i waho. ʻO ka lāʻau opioid (Difenoxin) i loko o kēia lāʻau lapaʻau e hoʻolohi i nā ʻiʻo o loko o nā ʻōpū ma ka 100% a lohi (Hoʻemi i ka neʻe ʻana o GI). A laila, i ka wā e noho ai ka ʻōpala i loko o nā ʻōpū, omo maikaʻi ia i ka wai a pau koke ka maʻi diarrhea. Kōkua pū ʻo Atropine (Anticholinergic) i ka hoʻomaloʻo ʻana i ke kahe ʻana o ka saliva/wai mai loko mai o nā ʻōpū.
💬 No ke aha he ʻuʻuku ka atropine i loko o kēia pila antidiarrheal? He aha nā pōʻino?
ʻO ka 'Difenoxin' i loko o kēia he lāʻau lapaʻau e like me Opioid! No laila, inā inu nui ʻoe i kēia, hiki iā ʻoe ke 'ʻona/kiʻekiʻe' loa. No ka pale ʻana i kēlā, ua hoʻohui ʻia ʻo 'Atropine' ma ke ʻano he hoʻopaʻi no ka poʻe e inu malū ana i kēia mau mea! Inā inu nui ʻoe i nā pila, hiki i kēia Atropine ke hoʻomaloʻo nui i ka waha, ka puʻuwai wikiwiki, a me ka paʻa ʻana o ka mimi (Anticholinergic toxicity). Eia kekahi, inā hāʻawi ʻia i nā keiki, hiki iā lākou ke hoʻōki i ka hanu ʻana (Respiratory depression) a make pū kekahi!
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