E aʻo kākou e pili ana i ka endothelium - kahi hale mana huna i loko o kou kino.

Ua ʻike kākou a pau e kahe ana ke koko ma o kākou kino, ʻeā? ʻAʻole wale kēia koko e kahe ana ma o kahi pūnaewele o nā ʻōmole i kapa ʻia he mau kīʻaha koko, e like me nā paipu wai. No laila, ua noʻonoʻo paha ʻoe i ke ʻano o loko o kēia mau ʻōmole? I kēia lā, e kamaʻilio kākou e pili ana i kahi papa lahilahi kupaianaha o nā ʻōmole e hoʻopili ana i loko o kēlā mau ʻōmole. Kāhea mākou i kēia ʻo 'endothelium' . ʻAʻole kēia he uhi wale nō, he ʻōnaehana ia o nā ʻōmole liʻiliʻi e hana ana i nā hana koʻikoʻi he nui e pili ana i ke olakino o kou kino holoʻokoʻa.

I ka ʻōlelo maʻalahi, he aha kēia endothelium?

E noʻonoʻo i kēlā me kēia kīʻaha koko i loko o kou kino ua uhi ʻia me kahi membrane lahilahi a laumania, hoʻokahi wale nō cell ka mānoanoa, e like me ka mural. ʻO ia ka endothelium. Ua hana ʻia ia me kahi ʻano cell kūikawā i kapa ʻia ʻo nā cell endothelial.

Loaʻa kēia endothelium like ma kēia mau wahi o kou kino:

• Nā Arteria: Nā kīʻaha nui e lawe i ke koko mai ka puʻuwai i nā ʻāpana ʻē aʻe o ke kino.
• Nā aʻa koko: ʻO nā kīʻaha koko e lawe i ke koko mai ke kino i ka puʻuwai.
• Nā Capillaries: Nā kīʻaha koko liʻiliʻi loa a maikaʻi loa.
• Nā capillaries lymph: Nā moku e pili ana i kā mākou ʻōnaehana lymphatic.

ʻAʻole ia he pā wale nō. Hana ia ma ke ʻano he kikowaena nui no ka hoʻololi ʻana i ka ʻike a me nā meaʻai ma waena o kou koko a me ke koena o nā ʻiʻo o kou kino. He mea nui loa ia, manaʻo nā kānaka ʻepekema i kēia manawa ʻo ka endothelium kekahi o nā ʻōkana nui loa i loko o ko kākou kino. ʻAe, he ʻōkana ia, e like me ke akepaʻa a me ka puʻuwai.

He aha ka lawelawe a ka endothelium e hāʻawi ai i ko mākou kino?

He mea kupaianaha ka hana a kēia papa liʻiliʻi o nā cell. E nānā kākou i kekahi o nā mea nui.

Hoʻomalu i ka ʻūlū a me ka hoʻonui ʻana o nā kīʻaha koko

Pono kou mau kīʻaha koko e hoʻonui (vasodilate) i ka wā e pono ai, a e hoʻohāiki (vasoconstrict) i ka wā e pono ai. Hoʻomalu ʻia kēia e ka endothelium.

E noʻonoʻo e pili ana i kēia ʻano.

• Ke hoʻoikaika kino ʻoe: Pono kou mau ʻiʻo i ke koko a me ka oxygen hou aku. Hoʻouna ka endothelium i nā hōʻailona e hoʻonui i nā kīʻaha koko ma ia wahi, e ʻae ana i ke koko e kahe maʻalahi.
• I kahi lā anuanu loa: Makemake ʻoe e mālama i ka wela o kou kino. ʻO kēia ke kumu o ka ʻūmiʻi iki ʻana o nā kīʻaha koko i loko o kou mau lima a me kou mau wāwae, e kōkua ana i ka hoʻomau ʻana i ke kahe ʻana o ke koko i kou mau kino nui.

Ma kēia ʻano, kōkua nui ia i ke kaohi ʻana i kou koko a me ka hōʻoia ʻana e loaʻa i nā ʻōkana āpau ka nui o ke koko e pono ai.

Hoʻokele i ka nui o ke wai e neʻe ana mai ke koko i nā ʻiʻo

Ua like ka endothelium me kahi kānana. ʻAe ia i nā meaʻai a me ka oxygen mai ke koko e hele i nā ʻiʻo, ʻoiai e hana ana ma ke ʻano he pale pale e pale ai i nā mea ʻino a me nā mea ʻawahia mai ke komo ʻana i ke koko. Eia nō naʻe, ke loaʻa iā ʻoe kahi maʻi, pono i kā mākou mau pūnaewele pale e puka i waho o ke koko a hele i kahi o ka maʻi. A laila hoʻomaʻemaʻe ka endothelium ponoʻī i ke ala no kēlā mau pūnaewele e hiki ai i laila.

Kāohi i ke kāpili ʻana o ke koko (Thrombosis)

ʻO ka maʻamau, he mea weliweli loa nā ʻōpū koko i loko o nā kīʻaha koko, ʻeā? Hiki iā ia ke hana i nā maʻi koʻikoʻi e like me nā hōʻeha puʻuwai a me nā hahau. Hoʻokuʻu ka endothelium olakino i nā kemika kūikawā e like me ka nitric oxide, ka mea e mālama ai i ke kahe koko a pale i ka clotting pono ʻole.

Pehea ka nui o ka endothelium? Aia ma hea ia i loko o ko kākou kino?

Inā nīnau kekahi iā ʻoe i hea kou puʻuwai, kuhikuhi ʻoe i kou umauma. Inā nīnau kekahi iā ʻoe i hea kou lolo, kuhikuhi lākou i kou poʻo. Akā inā nīnau kekahi iā ʻoe i hea ka endothelium, hiki iā ʻoe ke kuhikuhi i kekahi ʻāpana o kou kino. Ua laha loa ia ma ke kino holoʻokoʻa.

E noʻonoʻo wale, inā e hoʻomoe ʻia nā kīʻaha koko a pau o ke kanaka maʻamau mai ka piko a ka piko, e like paha lākou me 100,000 kilomita ka lōʻihi! Ua lawa kēlā e hele a puni ka honua i ʻelua manawa. A ua uhi ʻia kēia lōʻihi holoʻokoʻa me kēia endothelium. Inā ʻoe e lawe i kona wahi, ʻoi aku ka nui ma mua o kekahi mau kahua tennis. Eia kekahi, ua hana ʻia kēia ʻōnaehana holoʻokoʻa me nā pūnaewele endothelial he trillion (1,000,000,000,000).

He aha ka hana ʻino o ka Endothelial?

ʻO kēia ka ʻāpana koʻikoʻi loa a kākou e pono ai e makaʻala. ʻO ke ʻano o ka 'Endothelial Dysfunction' ʻo ia hoʻi ua hōʻino ʻia nā cell endothelial a ʻaʻole hiki ke hana pono i kā lākou hana. Ua like ia me ka hemo ʻana o ka asphalt ma ke alanui, e paʻakikī ai i nā kaʻa ke holo.

He aha ka mea e hana ai ke nāwaliwali ka endothelium iho?

Ke hōʻino ʻia ka endothelium, lilo kona ʻili laumania i ʻoʻoleʻa. A laila hoʻomaka ka cholesterol maikaʻi ʻole (LDL) e hōʻiliʻili ma kēlā mau wahi ʻoʻoleʻa. I ka pane ʻana, hele mai nā pūnaewele mai ka ʻōnaehana pale o ke kino a hōʻiliʻili ma laila. Hōʻiliʻili kēia mau mea a pau, a i ka hala ʻana o ka manawa, hana ia i kahi 'papa momona' (plaque) .

I ka ulu ʻana o kēia papa momona, e hāiki ana ke kīʻaha koko mai loko mai. A laila e keʻakeʻa kēia i ke kahe ʻana o ke koko. Inā i kekahi lā e pohā kēia papa momona, hiki ke hana ʻia kahi ʻūpā koko ma ia wahi a ālai loa i ke kīʻaha koko.

No laila, hiki i ke kanaka me ka endothelium nāwaliwali ke loaʻa i nā mea pilikia e hiki mai ana:

• Maʻi hohola
• Hahau
• Maʻi ʻaʻa coronary
• ʻO ka maʻi aʻa peripheral
• Maʻi puʻupaʻa
• Ke kū'ē ʻana o ka insulin

No laila pehea mākou e mālama ai i kēia endothelium i ke olakino?

ʻO ka nūhou maikaʻi, hiki iā kākou ke pale i kēia endothelium makamae ma ka hoʻololi ʻana i ko kākou nohona.

I ka ʻōlelo maʻalahi, hana ko mākou kino i kahi ʻano ʻāpana ʻino i kapa ʻia ʻo 'free radicals' . Hoʻopōʻino kēia i kā mākou mau cell endothelial. ʻO nā mea maikaʻi e kōkua ai i ka hoʻopau ʻana i kēia mau ʻāpana ʻino i kapa ʻia ʻo 'antioxidants' . No laila, ʻo ka mea e pono ai mākou e hana, ʻo ia ke hōʻemi i ka hana ʻana o nā radicals manuahi ma ka ʻai ʻana i nā meaʻai waiwai i nā antioxidants.

Nā mea maikaʻi e hana ai

E ʻai i nā meaʻai waiwai i nā antioxidants.

• Nā mea kanu ʻōmaʻomaʻo ʻeleʻele: spinach, kale, collard greens.
• Nā huaʻai a me nā mea kanu ʻōlinolino: nā tōmato, kāloti, beets, pepa bele, ʻalani, huaʻai.
• ʻO nā ʻano palaoa holoʻokoʻa: ka laiki ʻeleʻele, ka ʻoka, a me ka millet.
• Nā ʻaila olakino: ʻaila ʻoliva, ʻaila avocado.

Hiki iā ʻoe ke kamaʻilio me kāu kauka e pili ana i kēia ʻano meaʻai (e.g., ka meaʻai Mediterranean) a hana i nā hoʻololi e kūpono iā ʻoe.

Nā mea maikaʻi ʻole e pale aku ai

Hoʻonui kēia mau mea i nā radical manuahi i loko o kou kino.

• Puhipaka: ʻO kēia ka ʻenemi helu ʻekahi. E hoʻōki i kēia lā.
• Nā meaʻai kiʻekiʻe i ke kō a me nā mea ʻono: Hoʻonui kēia i ka mumū i loko o ke kino.
• Nā meaʻai i hana ʻia: Loaʻa paha i kēia mau mea nā momona a me nā kemika ʻino.
• Kaumaha nui loa.
• ʻAʻole lawa ka hiamoe.

Eia kekahi, he mea nui loa ka hoʻoikaika kino mau no ke olakino endothelial. Ke hoʻoikaika kino ʻoe, hoʻonui ʻia ka hana ʻana o ka nitric oxide, ka mea e mālama ai i ke olakino o kou mau kīʻaha koko. ʻOiai kekahi mea maʻalahi e like me ka hele wāwae no 30 mau minuke i ka lā hiki ke hana i kahi ʻokoʻa nui.

Inā loaʻa iā ʻoe kahi maʻi e like me ke koko kiʻekiʻe, ka maʻi diabetes, a i ʻole ka cholesterol, he mea nui e hahai pololei i ka hoʻolālā lapaʻau a kāu kauka . ʻO ka pahuhopu o kēia mau lāʻau lapaʻau ka kaohi ʻana i kēia mau kūlana a hōʻemi i ka hōʻino ʻana i kou endothelium.