Ke hoʻomaka nei ʻoe e ʻūlū ke hoʻopā ʻoe i kahi ʻāpana lepo? A i ʻole ke nahu ʻia ʻoe e kahi ʻanuʻu a i ʻole kahi makika, lilo ka ʻāpana i ʻulaʻula, pehu, a ʻānai nui? Ua loaʻa i ka nui o mākou nā ʻike like. No laila, i kēia lā e kamaʻilio mākou e pili ana i kahi mea nui i kuleana no kēia hopena e hana ʻia i loko o ko mākou kino i nā manawa e like me kēia. ʻO ia hoʻi nā "Mast Cells ".
I ka ʻōlelo maʻalahi, ʻo wai kēia mau pūnaewele mast?
He mau koa kūikawā nā pūnaewele mast i loko o kāu ʻōnaehana pale. E like me ko ko kākou ʻāina he pūʻali koa e pale aku iā ia, he ʻōnaehana pale pū ko ko kākou kino e pale aku iā ia. ʻO kēia mau pūnaewele mast nā kiaʻi i loko o kēlā ʻōnaehana, e makaʻala mau ana.
Hoʻopuka ʻia kēia mau pūnaewele i loko o ko kākou iwi iwi. A laila hele lākou ma ke koko a noho i loko o nā ʻiʻo like ʻole o ko kākou kino. Ma laila e hoʻomaka ai kā lākou hana. ʻO kā lākou hana nui ka pale ʻana iā kākou mai nā hoʻoweliweli like ʻole i ke kino.
Akā i kekahi manawa lilo kēia mau pūnaewele mast i mea hana nui. ʻO ia ka manawa e hoʻomaka ai nā pilikia. Hiki iā lākou ke hana i kahi hopena nui i nā mea ʻino ʻole e like me nā ʻuku lepo a i ʻole ka meaʻai. Kāhea mākou i kēia mau kūlana he 'allergies' a i ʻole 'allergic asthma'. I kekahi mau hihia koʻikoʻi, hiki i ka hana o kēia mau pūnaewele mast ke hana i kahi hopena allergies koʻikoʻi i kapa ʻia ʻo anaphylaxis, hiki ke hoʻoweliweli i ke ola.
Pehea e hana ai kēia mau pūnaewele mast? E hoʻomaopopo kākou i kēia 'ʻōnaehana alarm'!
E noʻonoʻo i kou kino e like me kahi pā kaua nui. Ua like nā pūnaewele mast me kahi ʻōnaehana makaʻala i hoʻokomo ʻia ma nā wahi āpau ma nā paia o kēlā pā kaua. Ua mākaukau mau kēia ʻōnaehana hoʻāla e pale i ke kino mai nā ʻenemi o waho, ʻo ia hoʻi, nā pathogens e like me nā virus a me nā bacteria, a me nā mea ʻawahia e like me ka venom nahesa a me ka venom nalo.
ʻO ka mea nui, ʻaʻole hele pololei nā pūnaewele mast e hakakā i nā germs. ʻO kā lākou hana, ʻo ia ke "hoʻonohonoho i ka alarm" ke hiki mai kahi ʻenemi a hoʻouna i kahi leka i ke koena o ka ʻōnaehana pale (nā ʻāpana koko keʻokeʻo ʻē aʻe).
E nānā kākou pehea e hana ai kēia kaʻina hana me nā kikoʻī hou aku:
1. Ke ʻike ʻana i ka ʻenemi: ʻO ka mea mua, ke komo kahi germ a i ʻole allergen hou i loko o kou kino, ʻike kahi ʻāpana o ka ʻōnaehana pale i kapa ʻia ʻo B-cells iā ia.
2. Ka hana ʻana i nā mea kaua kūikawā: Ma hope o ka ʻike ʻana i ka ʻenemi, hoʻomaka nā cell-B e hana i kahi ʻano antibody i kū pono i kēlā ʻenemi. Ua kapa ʻia kēia mau antibodies he immunoglobulin E (IgE) .
3. Ke hoʻolako nei i nā kiaʻi me nā mea kaua:Hoʻopili kēia mau antibodies IgE i hana ʻia i ka ʻili o nā cell mast, nā meʻe o kā mākou moʻolelo. Ua like ia me ka hāʻawi ʻana i kahi mea kaua i kahi kiaʻi.
4. Kani ka leo hoʻāla: I kēia manawa, ua makaʻala loa nā pūnaewele mast me kā lākou mau mea kaua IgE. I ka manawa aʻe e komo hou ai ka ʻenemi like (ʻo ia hoʻi ka germ like a i ʻole ka allergen) i ke kino, e hopu ʻia e ka IgE i hoʻopili ʻia i nā pūnaewele mast. ʻO ia ka manawa e "hoʻāla ʻia" ai nā pūnaewele mast.
5. Hoʻouka kaua Histamine: Ke hoʻāla ʻia, hoʻokuʻu nā pūnaewele mast i kahi nui o nā kemika i mālama ʻia i loko o lākou i ka manawa hoʻokahi. ʻO ka histamine ka mea nui loa o kēia mau kemika.
E nānā kākou i ka mea e hana ʻia i loko o ko kākou kino ke hoʻokuʻu ʻia kahi kemika i kapa ʻia ʻo histamine.
| He aha ka mea e hana ʻia ma muli o ka histamine? | Ka hopena (pehea kou manaʻo) |
|---|---|
| Hoʻonui ia i nā kīʻaha koko, e ʻae ana i nā pūnaewele pale e hiki maʻalahi i ka wahi. | ʻUlaʻula o ka ʻili, mehana a me ka pehu ʻana o ka wahi. |
| Hoʻonui i ka hana ʻana o ka mucus. | Ihu wai, ʻūhū, ʻūhā. |
| Hoʻoulu i ka ʻuʻuku ʻana o nā ʻiʻo laumania ma ke ala hanu a me ke ala ʻai. | Paʻakikī ka hanu ʻana (e like me ka hānō), ʻeha ʻōpū, luaʻi, a i ʻole ka maʻi pākī. |
| Hoʻoulu i nā hopena o ke aʻalolo. | ʻIli ʻāʻī, ʻulaʻula (hives). |
I kēia manawa ua maopopo iā ʻoe ka mea e hana ʻia i ke kino ke loaʻa iā mākou kahi maʻi allergy, ʻeā? ʻOiai ua hana ʻia kēia mau mea a pau e pale iā mākou, i kekahi manawa lilo kēia pane i mea koʻikoʻi loa.
Ma hea i loko o ke kino i nui loa ai kēia mau pūnaewele mast?
Hoʻonoho nui ʻia kēia mau kiaʻi ma nā puka komo nui kahi e komo mai ai nā germs a me nā allergens mai ke kaiapuni waho iā mākou. ʻO ia hoʻi:
- ʻAla hanu a me nā māmā: E pale iā ʻoe iho mai nā mea e hele mai me ka ea a kākou e hanu nei.
- ʻŌnaehana hoʻoheheʻe (ʻōnaehana GI): E pale iā ʻoe iho mai nā germs e hele mai me nā mea a mākou e ʻai ai a inu ai.
- ʻIli: E pale iā ʻoe iho mai nā mea e komo ana ma o ka ʻili o ka ʻili.
- Loaʻa pū kēia mau pūnaewele a puni nā kīʻaha koko a me nā aʻalolo .
He aha nā maʻi e pili ana me nā pūnaewele mast?
Ke hana hewa nā pūnaewele mast, hiki ke loaʻa nā ʻano maʻi like ʻole. He mea maʻamau a ʻike nui ʻia kekahi o lākou.
| Kūlana olakino | He hoʻolauna pōkole |
|---|---|
| Nā kūlana maʻamau |
|
| Nā kūlana kakaikahi |
E makaʻala i kēia mau hōʻailona.
Hiki i nā hōʻailona o ka maʻi mast cell ke komo pū:
- ʻUlaʻula ka ʻili, ka maneʻo, ka manaʻo o ka mehana.
- Ka pehu ʻana (edema) ma nā ʻāpana like ʻole o ke kino.
- Paʻakikī ka hanu ʻana.
- Nā hopena alerika koʻikoʻi (anaphylaxis).
Inā loaʻa pinepine kēia mau hōʻailona iā ʻoe, he mea nui loa ke ʻike ʻana i ke kauka no ka ʻōlelo aʻo ma mua o ka lāʻau ponoʻī.
Pehea e ʻike ai ke kauka i kēia mau kūlana? He aha nā lāʻau lapaʻau?
Inā kānalua kāu kauka he maʻi mast cell kou ma muli o kāu mau hōʻailona, hiki iā ia ke kauoha i nā hoʻokolohua like ʻole.
- Nā hoʻāʻo koko
- Nā hoʻāʻo mimi
- Hoʻāʻo ʻili allergy
- I kekahi manawa lawe ʻia kahi hāpana liʻiliʻi o ka iwi iwi a i ʻole ka ʻili no ka hoʻāʻo ʻana (kahi 'biopsy').
ʻOkoʻa nā koho lapaʻau mai kēlā mea kēia mea maʻi a ma muli o ke ʻano o ke kūlana. Hiki i nā lāʻau lapaʻau maʻamau ke komo pū me:
- Ke pale ʻana i nā allergens: Ke ʻike nei i nā mea āu e maʻi ai a me ka noho mamao aku mai iā lākou.
- Nā lāʻau lapaʻau: Nā lāʻau lapaʻau i hāʻawi ʻia e kāohi i nā hōʻailona. ʻO nā laʻana e komo pū me nā antihistamines a me montelukast.
- Nā mea hoʻopaʻa pūnaewele Mast: Hana kēia mau lāʻau lapaʻau ma ka hoʻōki ʻana i ka hoʻokuʻu ʻia ʻana o nā kemika e like me ka histamine mai nā pūnaewele mast.
- Nā lāʻau lapaʻau pilikia: Nā lāʻau lapaʻau e like me ka epinephrine no ka anaphylaxis koʻikoʻi.
E hoʻomanaʻo, ua hoʻoholo ʻia kēia mau lāʻau lapaʻau a pau e ke kauka nāna ʻoe e nānā. No laila, e hahai pono i kāna mau kuhikuhi.
ʻO ka mea hope loa, he maikaʻi a maikaʻi ʻole paha nā pūnaewele mast?
Lohe wale ka hapa nui o ka poʻe e pili ana i nā pūnaewele mast ke loaʻa iā lākou kahi maʻi pilikia e like me ka maʻi allergy, no laila manaʻo paha lākou he mea maikaʻi ʻole lākou. Akā ʻo ka ʻoiaʻiʻo, he ʻāpana koʻikoʻi a koʻikoʻi loa nā pūnaewele mast o ka ʻōnaehana pale o ko mākou kino.
ʻO ka hapa nui o ka manawa, pale lākou iā mākou mai nā maʻi a me nā germs. I ka wā e nui ai ko lākou hoihoi, loaʻa iā mākou nā maʻi allergies. E like me kahi hui o nā kiaʻi nui e hoʻā ana i ke kauhale holoʻokoʻa i ke ahi e hopu i kahi ʻaihue liʻiliʻi.
No laila, i ka manawa aʻe e ʻū ai ʻoe a e ʻōpala paha iā ʻoe iho, e hāʻawi i kēia mau pūnaewele mast liʻiliʻi i kahi mahalo nui. No ka mea, hana nui lākou e pale iā ʻoe!
Leka Lawe-Home
- He ʻano cell koʻikoʻi nā mast cell i loko o kā mākou ʻōnaehana pale kino nāna e pale iā mākou mai nā germs.
- ʻO nā kūlana e like me nā maʻi allergies, ka hānō, a me nā ʻulaʻula ʻili e kū mai ana ke pane nui kēia mau cell mast i nā mea ʻino ʻole a hoʻokuʻu i nā kemika e like me ka histamine.
- Inā loaʻa iā ʻoe nā hōʻailona allergies pinepine a koʻikoʻi paha (e like me ka paʻakikī o ka hanu ʻana, ka pehu ʻana o ka maka), mai hoʻowahāwahā iā ia.
- Ma ia ʻano kūlana, he mea nui loa ke kūkākūkā me ke kauka kūpono a loaʻa ka ʻōlelo aʻoaʻo a me ka lāʻau lapaʻau kūpono, ma mua o ka hoʻoholo ʻana i kāu iho.
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