Inā loaʻa kekahi o kou ʻohana, ʻo kou makuahine paha, kou makuakāne, a i ʻole kahi mea aloha paha, i ka maʻi Alzheimer, ua ʻike mākou i kona paʻakikī. ʻAʻole hiki i nā huaʻōlelo ke wehewehe i ke kaumaha a me ke kōkua ʻole āu e manaʻo nei i ka nalowale mālie ʻana o kou hoʻomanaʻo a ʻaʻole ʻoe e ʻike hou i kāu poʻe aloha. Eia naʻe, aia i kēia manawa kahi ʻālohilohi o ka manaʻolana i loko o kēia pouli. I kēia manawa koke nei, ua ʻāpono ka US Food and Drug Administration (FDA) i kahi lāʻau hou no ka maʻi Alzheimer.
He aha kēia lāʻau lapaʻau hou?
ʻO ka inoa o kēia lāʻau lapaʻau i ʻāpono hou ʻia ʻo donanemab . Hele mai ia i ka mākeke ma lalo o ka inoa ʻo Kisunla. ʻAʻole kēia he lāʻau lapaʻau i hāʻawi ʻia i nā poʻe maʻi Alzheimer āpau. Kuhikuhi kūikawā ʻia ia i nā poʻe i nā pae mua o ka maʻi. ʻO ia hoʻi, ʻo ka poʻe i hoʻomaka wale e hōʻike i kekahi hemahema i ka hoʻomanaʻo a me nā mākau noʻonoʻo. Ma ke ʻano lapaʻau, kūpono ia no nā poʻe maʻi me ka hemahema cognitive a i ʻole ka dementia akahai .
I ka ʻōlelo maʻalahi, ua hoʻokumu ʻia ka maʻi Alzheimer e ka hōʻiliʻili ʻana o kahi ʻano protein makemake ʻole ʻia i kapa ʻia ʻo amyloid i loko o ka lolo. Ua like ia me kahi paʻa i loko o kahi paipu wai i hoʻokumu ʻia e ka lepo. Ma mua o ka hāʻawi ʻia ʻana o kēia lāʻau lapaʻau hou, pono e hana ʻia kahi scan e hōʻoia inā loaʻa i ka mea maʻi kēia mau waihona amyloid i loko o ko lākou lolo.
He aha ka mea kūikawā nui e pili ana i kēia lāʻau lapaʻau?
ʻO ka mea nui a koʻikoʻi loa e pili ana i kēia lāʻau lapaʻau, ʻaʻole ia he lāʻau lapaʻau no ke ola holoʻokoʻa. E noʻonoʻo, he nui nā lāʻau lapaʻau o kēia manawa e like me kēia e pono e lawe mau ʻia. Akā ʻo ka ʻokoʻa kipi me ka lāʻau donanemab, hiki ke hoʻōki ʻia ka lāʻau lapaʻau ma hope o ka wehe ʻia ʻana o kēlā mau waihona amyloid i makemake ʻole ʻia i loko o ka lolo.
He ʻanuʻu nui kēia i mua. Hāʻawi kēia ʻae ʻana i nā mea maʻi i nā koho hou aʻe, a me ka manawa kūpono e hoʻolilo i ka manawa hou aku me kā lākou poʻe aloha, me nā hoʻomanaʻo hou aʻe.
Manaʻo nā loea ma ka hoʻōki ʻana i ka lāʻau lapaʻau ma kēia ʻano, hiki ke hoʻemi nui ʻia ka nui o nā manawa e pono ai ka mea maʻi e kipa aku i ka haukapila, ka ʻoluʻolu ʻole a lākou e ʻike ai, a me ke kumukūʻai o ka lāʻau lapaʻau.
ʻAʻohe pilikia a i ʻole nā hopena ʻaoʻao?
ʻOiaʻiʻo, e like me nā lāʻau lapaʻau āpau, aia kekahi mau pilikia. ʻAʻole hiki iā mākou ke hoʻowahāwahā iā lākou. ʻO ka pilikia nui e pili ana me kēia lāʻau lapaʻau he kūlana i kapa ʻia ʻo ARIA (Amyloid-Related Imaging Abnormalities) .
I ka ʻōlelo maʻalahi, hiki i kēia ke hana i kahi pehu liʻiliʻi i loko o ka lolo (edema o ka lolo) a i ʻole ke kahe koko liʻiliʻi loa (ke kahe koko o ka lolo) . He mea weliweli paha kēia mau ʻōlelo, akā ʻōlelo nā loea hiki ke mālama ʻia kēia pilikia. No laila he mea nui e makaʻala i ia mea i ka wā o ka mālama ʻana.Nānā pono ʻia ka lolo ma o ka hana ʻana i nā scan MRI maʻamau. Inā ʻike ʻia kekahi mau loli, e hana ke kauka i nā hana e pono ai.
No laila, inā ʻoe e noʻonoʻo nei i kēia lāʻau lapaʻau, he mea nui loa e kamaʻilio ākea me kāu kauka e pili ana i nā pono a me nā pōʻino o kēia lāʻau lapaʻau, ʻo ia hoʻi, nā pono a me nā pilikia, me ka hūnā ʻole i kekahi mea.
| Nā Pōmaikaʻi o Donanemab | Nā pōʻino a me nā pilikia o Donanemab |
|---|---|
| Wehe i nā waihona amyloid i loko o ka lolo e hoʻoulu ai i ka maʻi Alzheimer. | Ka pilikia o ARIA (pehu ʻana o ka lolo a i ʻole ke kahe ʻana o ke koko). |
| Hoʻolohi i ka wikiwiki o ka hōʻemi ʻana o ka hoʻomanaʻo a me ka hiki ke noʻonoʻo. | He mea nui e nānā pinepine i ka lolo me ka hoʻohana ʻana i ka MRI. |
| Ka hiki ke ho'ōki i ka lā'au lapa'au ke pau ka amyloid. | Hiki ke loaʻa nā hopena ʻaoʻao maʻamau e like me ka ʻeha poʻo a me ka luaʻi. |
| Hoʻemi i ka manawa lapaʻau a me ke kumukūʻai i ka wā lōʻihi. | ʻAʻole kēia he lāʻau lapaʻau e hoʻōla loa i ka maʻi, akā, hoʻomalu wale ia i ka hoʻonui ʻia ʻana o ka maʻi. |
Loaʻa anei kēia lāʻau lapaʻau ma ko kākou ʻāina?
I kēia manawa, ua ʻae ʻia ʻo donanemab ma ʻAmelika Hui Pū ʻIa wale nō. No laila e lōʻihi ka manawa e loaʻa ai kēia lāʻau lapaʻau ma nā haukapila o Sri Lanka. Eia kekahi, he pipiʻi iki. Eia nō naʻe, inā e hiki mai kēia lāʻau lapaʻau i Sri Lanka i ka wā e hiki mai ana, hiki paha i nā mea maʻi ke loaʻa i kahi hōʻoluʻolu me ke komo ʻana o ke aupuni a me ka uhi ʻinikua.
Eia nō naʻe, ʻo nā ʻike hou e like me kēia e hōʻike ana e holomua mālie ana ka ʻepekema i ke kaua ʻana i ka maʻi Alzheimer. ʻO ia iho ka mea e hāʻawi mai iā mākou i ka manaʻolana nui.
Leka Lawe-Home
- He lāʻau lapaʻau hou ʻo Donanemab i ʻāpono ʻia no nā pae mua o ka maʻi Alzheimer.
- Hoʻopau kēia i nā protein amyloid ʻino e hōʻiliʻili ana i loko o ka lolo a hoʻolohi i ka holomua o ka maʻi.
- He mea nui e hoʻomaopopo ʻaʻole kēia he lāʻau lapaʻau no nā mea āpau.
- ʻO ka pōmaikaʻi nui o kēia lāʻau lapaʻau, hiki ke hoʻōki ʻia ke hoʻomaʻemaʻe ʻia ka amyloid mai ka lolo.
- Ma muli o ka hiki ke hoʻomohala i nā kūlana weliweli e like me ARIA, he mea nui ka nānā pono ʻana e ke kauka a me nā scan MRI i ka wā o ka mālama ʻana.
- Ma mua o ka hoʻoholo ʻana i kekahi mau hoʻoholo e pili ana i kou olakino a i ʻole ko kahi mea aloha, e kūkākūkā mau i nā koho āpau, nā pono, a me nā pilikia me kāu kauka.
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