Loaʻa pinepine iā ʻoe ke anu, ka ʻū, a me ka ʻāʻī ʻeha? A i ʻole e loaʻa maʻalahi iā ʻoe mai kahi mea kokoke iā ʻoe nona kahi maʻi liʻiliʻi? Loaʻa pinepine ka maʻi o kekahi poʻe ma mua o nā poʻe ʻē aʻe. Manaʻo mākou ʻo ko lākou "ʻano" wale nō ia. Akā, ʻaʻole ia ka hihia mau. ʻO kekahi kumu no kēia he nāwaliwali iki paha i ka ʻōnaehana pale o ko mākou kino, ʻo ia hoʻi, ka ʻōnaehana pale. I kēia lā, ke kamaʻilio nei mākou e pili ana i ka IgA Deficiency, kahi maʻi maʻamau i ʻike ʻole ʻia e ka poʻe he nui.
I ka ʻōlelo maʻalahi, he aha ka hemahema o IgA?
Loaʻa i ko kākou kino kona pūʻali koa pale ponoʻī, e like me kahi ʻāina. Kāhea mākou i kēia ʻōnaehana ʻo ka ʻōnaehana pale kino . ʻO ka hana nui o kēia ʻōnaehana, ʻo ia ka ʻike a me ka luku ʻana i nā germs e like me nā virus a me nā bacteria e komo i loko o ke kino mai waho, a e pale iā kākou mai nā maʻi.
Aia nā ʻano koa like ʻole i loko o kēia pūʻali koa palekana. ʻO kekahi koa kūikawā i kapa ʻia ʻo Immunoglobulin . ʻO kēia kekahi ʻano protein a ko mākou kino e hana ai. Aia kekahi mau ʻano o kēia mau immunoglobulins. E like me A, G, M, E, D.
ʻO ka IgA a mākou e kamaʻilio nei i kēia lā he ʻano immunoglobulin A. He hiʻohiʻona kūikawā ko kēia IgA. Hoʻokomo nui ʻia ia i loko o nā membrane mucous o ko mākou kino. ʻO ia hoʻi:
- Nā maka
- Nā pepeiao
- Waha a me ka puʻu
- ʻŌnaehana hanu (ʻōnaehana hanu)
- ʻŌnaehana hoʻoheheʻe (ʻōpū)
ʻO kēia nā wahi e hiki ai i nā germs ke komo maʻalahi i ko kākou kino. No laila, noho kēia kiaʻi i kapa ʻia ʻo IgA ma kēia mau puka a pale i nā germs mai ke komo ʻana.
ʻO ke ʻano o ka hemahema o IgA , ʻaʻole lawa ka hana ʻana o ke kino o ke kanaka i kēia protein pale i kapa ʻia ʻo IgA. He kakaikahi wale nō ka hana a kekahi poʻe. ʻAʻole paha e hana iki kekahi.
E noʻonoʻo ʻoe e hana ana i kahi puzzle jigsaw nui. Inā nele ʻoe i kekahi mau ʻāpana, ʻaʻole e piha ke kiʻi, ʻeā? E nānā hakahaka kekahi mau wahi. Pēlā nō ka hemahema o IgA. I ke kiʻi piha o kā mākou ʻōnaehana pale, nele kekahi mau ʻāpana IgA.
Akā ʻo ka mea maikaʻi loa, ʻo ia ka hapa nui o ka manawa, hoʻāʻo nā koa ʻē aʻe o kā mākou ʻōnaehana pale (e like me IgG a me IgM) e hoʻoponopono i kēia hemahema i kekahi ʻano. ʻO ia ke kumu ʻaʻole ʻike ka hapa nui o ka poʻe me ka hemahema IgA i kekahi mau hōʻailona a i ʻole nā pilikia i ko lākou ola. ʻAʻole lākou i ʻike he maʻi ko lākou.
He aha nā hōʻailona o ka hemahema o IgA?
E like me kā mākou i ʻōlelo ai ma mua, ʻaʻohe hōʻailona o ka hapa nui o ka poʻe. Eia nō naʻe, hiki i kekahi poʻe ke ʻike i kekahi mau hōʻailona. ʻO ka mea nui o kēia mau mea, ʻo ia ka loaʻa pinepine ʻana o nā maʻi ma mua o nā poʻe ʻē aʻe.
E noʻonoʻo i kahi kanaka i kapa ʻia ʻo Nimali. Inā loaʻa kekahi i loko o kona keʻena i ke anu, ʻo Nimali ka mea aʻe e loaʻa. ʻOiai e hoʻomaikaʻi ana kekahi i loko o ʻelua a ʻekolu paha lā, e lilo ana ʻo Nimali ma kahi o hoʻokahi pule. I kekahi manawa e holomua ana ia i ka sinusitis. ʻO kēia ka mea e ʻike ai ke kanaka me ka hemahema IgA.
E nānā kākou i ka papa ma lalo nei e ʻike i nā pilikia e hiki ke kū pinepine ma muli o kēia kūlana.
| Nā maʻi ʻoi aku ka nui o ka hiki ke loaʻa | Nā kūlana olakino ʻē aʻe e pili ana paha |
|---|---|
| nā maʻi maka (ʻoi aku ka maka ʻulaʻula) | Asthma |
| Nā maʻi pepeiao | Nā ʻano maʻi like ʻole (Allergies) |
| Nā maʻi sinus | Ka maʻi pākī mau |
| ʻO ka Bronchitis a me nā maʻi ʻeha o ka ʻōpū hanu kiʻekiʻe | Nā maʻi ʻōpū (e.g. Ulcerative Colitis, Crohn's Disease) |
| Pneumonia | Nā maʻi Autoimmune |
No ke aha lā e kū mai ai kēia kūlana?
ʻO ke kumu nui o ka hemahema o IgA, ʻo ia ka genetic . ʻO ke ʻano kēia, ua hoʻoilina ʻia nā loli genetic e pili ana i ke kūlana mai nā mākua a i nā keiki. Inā loaʻa i kekahi o kou ʻohana, ʻoiai kou mau mākua, ke kūlana, ʻoi aku ka nui o kou pilikia o ka loaʻa ʻana ma kahi o 50 mau manawa ma mua o nā poʻe ʻē aʻe.
ʻAʻole pinepine loa, hiki i nā pae IgA haʻahaʻa ke lilo i hopena ʻaoʻao o ka hoʻohana lōʻihi ʻana i kekahi mau lāʻau lapaʻau. Eia kekahi laʻana:
- Nā lāʻau pale kino
- ʻO kekahi mau lāʻau anti-epileptic (e.g. Phenytoin)
- ʻO kekahi mau lāʻau lapaʻau no nā maʻi hono (e like me Penicillamine, Sulfasalazine)
He aha nā pilikia a me nā hopena ʻē aʻe o kēia maʻi?
ʻAʻole pilikia ka hapa nui o ka poʻe. ʻO ka pilikia nui e hiki mai ana, ʻo ia ka maʻi pinepine.
Eia nō naʻe, ʻoi aku ka nui o ka pilikia o ka poʻe me ka hemahema o IgA i ka hoʻomohala ʻana i nā maʻi autoimmune ma mua o ka heluna kanaka maʻamau.
He aha kēia mau maʻi autoimmune?
I ka ʻōlelo maʻalahi, ʻo ia ka manawa e hana hewa ai ka ʻōnaehana pale o ko kākou kino. ʻO ia hoʻi, ma kahi o ka hoʻouka ʻana i nā germs haole, hoʻomaka ia e hoʻouka i kā kākou mau cell a me nā ʻiʻo olakino ponoʻī. Hoʻoulu kēia i nā maʻi like ʻole.
ʻO kekahi o nā maʻi e pili ana me ka hemahema o IgA:
- Rheumatoid Arthritis: He maʻi e hoʻoulu ai i ka pehu a me ka ʻeha i nā hono.
- Lupus: He maʻi e hiki ke hoʻopilikia i nā ʻano kino like ʻole.
- ʻO ka maʻi Celiac: ʻO ia ke ʻano e pane ai ke kino i ka gluten (kahi protein i loaʻa i ka palaoa huita).
Ke kumu nei anei ka nele o IgA i ka luhi?
He nīnau kēia a ka poʻe he nui e nīnau ai. ʻAʻole hiki i ka hemahema o IgA ke kumu pololei i ka luhi. Eia nō naʻe, inā loaʻa iā ʻoe kekahi o nā maʻi autoimmune a mākou i kūkākūkā ai ma mua, hiki iā ʻoe ke ʻike i ka luhi nui ma ke ʻano he hōʻailona o kēlā maʻi. No laila, inā loaʻa iā ʻoe ka luhi i wehewehe ʻole ʻia, he mea nui loa ia e kamaʻilio me kāu kauka e pili ana i ia mea.
Pehea e ʻike ai ke kauka i kēia? He aha ka lāʻau lapaʻau?
ʻIkepili
He mea maʻalahi loa ka ʻike ʻana i ka hemahema o IgA. Pono wale nō ia i kahi hoʻāʻo koko . Ana kēia hoʻāʻo i nā pae o nā immunoglobulins like ʻole i loko o kou koko. Inā haʻahaʻa loa a ʻaʻohe paha kāu mau pae IgA, hiki i kāu kauka ke hōʻoia i ke kūlana.
ʻO ka hapa nui o ka manawa, ʻike ʻia kēia ma ka manawa kūpono. ʻIke wale ʻia nā pae IgA haʻahaʻa ke hana ʻia kahi hoʻāʻo koko no kekahi maʻi ʻē aʻe. Inā ʻike ʻoe he maʻi kēia i kekahi o kou ʻohana, he mea nui e haʻi i kāu kauka.
Lapaʻau
ʻO ka mea nui e hoʻomaopopo ai ma ʻaneʻi, ʻaʻohe lāʻau lapaʻau kūikawā no ka hemahema IgA, no ka mea, ua hoʻokumu ʻia e kahi mutation genetic i loko o ko mākou kino.
No laila he aha ka hana a ke kauka? ʻAʻole ʻo ia e mālama i ka hemahema IgA, akā, ʻo nā hōʻailona a me nā maʻi e loaʻa mai ana.
- Inā loaʻa iā ʻoe kahi maʻi bacteria, e hāʻawi ʻia ʻoe i nā antibiotics .
- Inā loaʻa iā ʻoe nā maʻi pinepine a koʻikoʻi, hiki ke hāʻawi ʻia iā ʻoe i kekahi manawa ka immunoglobulin ma o ka saline e hoʻoikaika i kāu ʻōnaehana pale.Hiki ke ʻōlelo ʻia e hoʻokomo i ka IVIG, akā hana kākaʻikahi ʻia kēia.
- Inā loaʻa iā ʻoe ka hānō, nā maʻi allergies, a i ʻole kahi maʻi autoimmune, e hāʻawi ʻia ʻoe i ka lāʻau kūpono.
No kekahi mau keiki, hiki i nā pae IgA ke hoʻi mālie i ka maʻamau i ko lākou wā ʻelemakule, akā ʻaʻole kēia ka hihia no nā mea āpau.
Āhea wau e ʻike ai i ke kauka?
Inā manaʻo ʻoe e maʻi mau ana ʻoe, a inā manaʻo ʻoe e lōʻihi ana kou manawa e hoʻōla ai mai kahi maʻi liʻiliʻi, e ʻike pono i ke kauka. Inā loaʻa iā ʻoe nā hōʻailona hiki ʻole iā ʻoe ke wehewehe, e kamaʻilio e pili ana iā lākou.
ʻAʻole maʻamau ka maʻi mau ʻana. No laila, ʻoiai inā he mea liʻiliʻi ia, mai makaʻu e kamaʻilio me kāu kauka e pili ana i ia mea, me ka noʻonoʻo ʻana, "ʻO wau nō kēia."
E nīnau kāu kauka iā ʻoe i nā nīnau, e nānā iā ʻoe, a, inā pono, e hana i kahi hoʻāʻo koko e kōkua i ka ʻike ʻana i ke kumu.
Leka Lawe-Home
- He maʻi maʻamau a ʻoluʻolu hoʻi ka hemahema o ka IgA o ka ʻōnaehana pale. ʻAʻole ʻike ka hapa nui o ka poʻe i kekahi mau hōʻailona.
- Inā kū mai nā hōʻailona, ʻike nui ʻia lākou ma ke ʻano o nā maʻi pinepine o ka ʻōnaehana hanu, nā pepeiao, nā maka, a me nā ʻōpū.
- Hiki ke ʻike ʻia kēia me kahi hoʻāʻo koko maʻalahi. ʻOiai ʻaʻohe lāʻau lapaʻau kūikawā no kēia ʻano, hiki ke mālama pono ʻia nā maʻi a me nā kūlana ʻē aʻe e hopena mai ana.
- Inā manaʻo ʻoe e maʻi mau ana ʻoe, mai hopohopo wale nō ia mea , akā e ʻimi i kāu kauka no ka ʻōlelo aʻo.
- Inā loaʻa iā ʻoe kēia maʻi, he mea nui loa ia e hahai i nā hana olakino maikaʻi, e like me ka holoi pinepine ʻana i kou mau lima a me ka noho mamao aku mai ka poʻe maʻi, i mea e pale ai iā ʻoe iho mai ka maʻi.
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