ʻO ka hoʻomaka ʻana i ka mālama ʻana i ka maʻi kanesa nou a i ʻole kahi mea aloha hiki ke lilo i manawa hopohopo a huikau. Loaʻa paha iā ʻoe nā nīnau e pili ana i nā lāʻau lapaʻau a kāu kauka e hāʻawi nei iā ʻoe, ko lākou mau inoa, a me nā hopena ʻaoʻao. No laila i kēia lā e kamaʻilio mākou e pili ana i kekahi lāʻau lapaʻau kūikawā no ka maʻi kanesa, ʻo Selpercatinib . Ua ʻike paha ʻoe iā ia ma ka inoa inoa ʻo Retevmo. E kamaʻilio kākou e pili ana i kēia lāʻau, kāna hana, a me nā mea e pono ai ke makaʻala ma ke ʻano maʻalahi a maʻalahi hoʻi e hoʻomaopopo.
He aha ka mea e hana maoli me kēia lāʻau lapaʻau?
I ka ʻōlelo maʻalahi, ʻaʻole like ʻo Selpercatinib me ka chemotherapy kuʻuna. Hana ia e like me ka "lāʻau lapaʻau i kuhikuhi ʻia." Hoʻouna kekahi mau protein i loko o ko kākou kino i nā hōʻailona i nā hunaola kanesa e "ulu hou aku, pālahalaha wikiwiki." E noʻonoʻo iā ia e like me kahi kuapo e hoʻoulu ai i nā hunaola kanesa. ʻO ka mea a Selpercatinib e hana ai, ʻo ia ke hoʻopau i ka protein e hoʻouna ana i ka hōʻailona hewa . Ua like ia me ka hoʻopau ʻana i kēlā kuapo. A laila ua kāohi ʻia ka ulu ʻana a me ka laha ʻana o nā hunaola kanesa ma ke kino holoʻokoʻa.
Nā mea e pono ai ʻoe e haʻi i kāu kauka ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau
Ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau, pono i kāu kauka ke loaʻa kahi kiʻi piha o kou olakino. E hōʻoia e haʻi iā lākou e pili ana i kekahi o kēia mau kūlana, ʻoiai inā loaʻa iā ʻoe kekahi:
| Loaʻa iā ʻoe kēia maʻi? | No ke aha he mea nui ka hoʻolaha? |
|---|---|
| Nā maʻi koko | Hiki i kēia lāʻau lapaʻau ke hoʻonui i ka pilikia o ke kahe ʻana o ke koko. |
| Ua hana ʻia nei a i ʻole ua hoʻonohonoho ʻia no ke ʻoki ʻana i ka wā e hiki mai ana | Hiki i ka lāʻau lapaʻau ke hoʻopaneʻe i ka ho'ōla ʻana o ka ʻeha. |
| Ke koko kiʻekiʻe | Hiki i ka lāʻau lapaʻau ke hoʻonui hou i ke koko. |
| Puʻuwai puʻuwai kūpono ʻole | Hiki ke loli ka helu o ka puʻuwai. |
| Nā maʻi o ke akepaʻa a i ʻole ka māmā | Hiki ke hoʻopilikia ʻia ka hana a kēia mau ʻōkana. |
| Nā maʻi ʻaleka i nā lāʻau lapaʻau ʻē aʻe, nā meaʻai, a i ʻole nā mea hoʻoluʻu | He mea nui e ʻike inā he maʻi ʻoe i ka lāʻau lapaʻau a i ʻole kekahi o kāna mau mea hoʻohui. |
| Ke hāpai nei a i ʻole e hoʻāʻo nei e hāpai | Hiki i kēia lāʻau lapaʻau ke hōʻeha nui i ka pēpē i hānau ʻole ʻia. |
| Ka hānai ʻana i ka waiū umauma | Hiki ke hoʻoili ʻia ka lāʻau lapaʻau i ka pēpē ma o ka waiū umauma. |
Pehea e pono ai iaʻu ke hoʻohana i kēia lāʻau lapaʻau?
He capsule kēia āu e lawe ai ma ka waha. He mea nui loa ia e lawe iā ia i ka manawa like i kēlā me kēia lā , e like me ke kauoha a kāu kauka.
- E ale i ke kāpule me ka wai . Mai uhaʻi, kuʻi, a nau paha i ke kāpule.
- Hiki iā ʻoe ke lawe i kēia me ka meaʻai a i ʻole me ka ʻole o ka meaʻai. Eia nō naʻe, inā ʻeha iki kou ʻōpū, ʻoi aku ka maikaʻi o ka lawe ʻana me ka ʻai.
- E hoʻomau i ka lāʻau lapaʻau a hiki i ka wā e ʻōlelo ai kāu kauka e hoʻōki.
- He mea nui loa: E pale i ka inu ʻana i ka wai pomelo a pau i ka wā e lawe ana i kēia lāʻau.
He aha inā e hala iaʻu kahi mahele o ka lāʻau lapaʻau?
Inā ʻoe e poina i kahi lāʻau lapaʻau, e lawe koke iā ia i kou hoʻomanaʻo ʻana. Eia nō naʻe, inā ʻoi aku ma mua o 18 mau hola ma hope o kāu lāʻau lapaʻau aʻe (ʻo ia hoʻi, ʻaʻole i hala ma mua o 6 mau hola a hiki i kāu lāʻau lapaʻau aʻe), e kāpae i ka lāʻau lapaʻau i poina a lawe i kāu lāʻau lapaʻau aʻe i ka manawa maʻamau. Mai lawe i ʻelua mau lāʻau lapaʻau i ka manawa hoʻokahi e hoʻopiha ai i kahi lāʻau lapaʻau i poina.
He aha inā lawe nui wau i ka lāʻau lapaʻau?
Inā manaʻo ʻoe ua lawe ʻoe i nā lāʻau lapaʻau ma mua o kou manaʻo, mai hopohopo. E hele koke i ka Halemai Pilikia (ETU) kokoke loa. A i ʻole, e kelepona i ke Kikowaena ʻIke ʻAi ʻona Lahui ma ka Halemai Lahui ʻo Colombo no ka ʻōlelo aʻoaʻo.
Nā mea ʻē aʻe e launa pū me kēia lāʻau lapaʻau
Hiki i kekahi mau lāʻau lapaʻau ke launa pū me Selpercatinib, e hoʻololi ana i kona pono a i ʻole e hoʻonui ana i nā hopena ʻaoʻao.
ʻŌlelo Aʻo: Inā ʻoe e lawe ana i kekahi o nā lāʻau lapaʻau ma lalo nei, mai lawe iā Selpercatinib. E kamaʻilio me kāu kauka e pili ana i kēia.
* ʻO Cisapride
* Dronedarone
* Ketoconazole
* Levoketoconazole
* Pimozide
* Thioridazine
Eia kekahi, hiki i nā lāʻau lapaʻau ʻē aʻe, nā huahana lāʻau lapaʻau, a me nā meaʻai ke launa pū me kēia lāʻau lapaʻau. No laila, he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei (me nā huaora, nā lāʻau lapaʻau lāʻau lapaʻau, a me nā mea hoʻohui).
- ʻO kekahi mau lāʻau koko kiʻekiʻe (diltiazem a i ʻole verapamil)
- ʻO kekahi mau lāʻau antiviral no ka maʻi HIV a i ʻole Hepatitis
- Nā lāʻau lapaʻau no nā maʻi fungal (itraconazole, posaconazole)
- Wai ʻāpala
- Nā lāʻau lapaʻau ʻē aʻe e hoʻololi i ka helu o ka puʻuwai
- ʻO Repaglinide no ka maʻi diabetes
- ʻO Rifampin no ka maʻi puʻupuʻu
- Nā huahana lāʻau lapaʻau e like me ka St. John's Wort
- Nā lāʻau lapaʻau e hoʻemi i ka waikawa o ka ʻōpū (e like me cimetidine, famotidine, ranitidine, lansoprazole, omeprazole)
Nā mea e makaʻala nui ai i ka wā e lawe ana i ka lāʻau lapaʻau
- Manaʻo maikaʻi ʻole: He mea maʻamau ke manaʻo iki i ka maikaʻi ʻole a i ʻole ka maikaʻi ʻole i ka wā e lawe ana i kēia lāʻau. ʻO kēia no ka mea e hoʻopilikia kēia lāʻau i nā hunaola kanesa a me nā hunaola olakino i kekahi ʻano. Eia naʻe, mai hoʻōki i ka lāʻau a hiki i ka wā e ʻōlelo aku ai kāu kauka iā ʻoe. E haʻi i kāu kauka e pili ana i nā hopena ʻaoʻao āu e ʻike ai.
- ʻOki kino: Inā e hana ʻia ʻoe i ke ʻoki kino (ʻoiai inā he mea liʻiliʻi e like me ka unuhi ʻana i ka niho), e haʻi i kāu kauka. Hiki i kēia lāʻau ke hoʻopaneʻe i ka ho'ōla ʻana o ka ʻeha. No laila, pono ʻoe e hoʻōki i ka lawe ʻana i ka lāʻau lapaʻau ma ka liʻiliʻi he 7 mau lā ma mua o ke ʻoki kino a hoʻomaka hou i 2 mau pule ma hope o ke ʻoki kino, ke ho'ōla piha ʻia ka ʻeha.
- Hāpai a me ka hānai waiū: No nā wāhine: E pale i ka hāpai ʻana i ka wā e lawe ana i kēia lāʻau lapaʻau a no hoʻokahi pule ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau. ʻO ia ke kumu he mea nui e hoʻohana i kahi ʻano kaohi hānau hilinaʻi. Pono ʻoe e lawe i kahi hoʻāʻo hāpai ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau e hōʻoia ʻaʻole ʻoe e hāpai. Eia kekahi, e pale i ka hānai waiū i kēia manawa a no hoʻokahi pule ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau. No nā kāne: E hoʻohana mau i ka condom inā moe ʻoe me kahi wahine i hiki ke hāpai i ka wā e lawe ana ʻoe i kēia lāʻau lapaʻau a no hoʻokahi pule ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau. Inā hāpai kāu hoa, hiki ke hoʻopilikia i ka pēpē i loko o ka ʻōpū.
- Ka hānau keiki: Hiki i kēia lāʻau lapaʻau ke hoʻopilikia i kou hiki ke loaʻa nā keiki. E kamaʻilio me kāu kauka inā he mau hopohopo kāu e pili ana i kēia.
- Ke koko:E nānā mau i kou koko e like me ka ʻōlelo a kāu kauka iā ʻoe. E ʻike i ke ʻano o ia mea a me ka manawa e pono ai ʻoe e kāhea aku i kāu kauka.
He aha nā hopena ʻaoʻao e hiki iaʻu ke ʻike?
E like me nā lāʻau lapaʻau āpau, hiki iā Selpercatinib ke hana i nā hopena ʻaoʻao. He koʻikoʻi kekahi, aʻo kekahi he mea maʻamau.
| Ka hopena ʻaoʻao | Wehewehena |
|---|---|
| Nā hopena ʻaoʻao e pono e hōʻike koke ʻia i kāu kauka | |
| Nā hopena alerika | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, nā lehelehe, ke alelo a i ʻole ka puʻu. |
| Ke kahe koko ʻano ʻē | ʻO ka ʻōpala ʻeleʻele a koko paha, ka luaʻi ʻana i ke koko e like me ke ʻano o ka lepo kofe, ka mimi ʻeleʻele/ʻulaʻula, nā kiko ʻulaʻula/poni ma ka ʻili. |
| Nā pilikia hanu | ʻŪhū maloʻo, paʻakikī ka hanu ʻana. |
| Nā loli i ka helu o ka puʻuwai | Nā palpitations o ka puʻuwai, ka poniuniu, ka ʻeha o ka umauma. |
| ʻEha o ke akepaʻa | ʻEha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, nalowale ka makemake e ʻai, melemele o ka ʻili a i ʻole nā maka, nā ʻōpala māmā, mimi melemele/ʻeleʻele. |
| ʻO ka hypothyroidism | Luhi maʻamau ʻole, hiki ʻole ke hoʻomanawanui i ke anu, ka paʻa ʻana o ka ʻōpū, ka hāʻule ʻana o ka lauoho, ka ʻili maloʻo, ka piʻi ʻana o ke kaumaha. |
| ʻO ka maʻi lysis puʻupuʻu (TLS) | Luaʻi, kahe ka wai, emi ʻana o ka mimi, ʻūlū ʻana o nā ʻiʻo, ʻeha nā hono, huikau. |
| E haʻi i kāu kauka inā hoʻomau a hoʻopilikia paha. | |
| Paʻa ka ʻōpū, ka maʻi kahe, ka waha maloʻo, ka luaʻi, ka ʻulaʻula o ka ʻili, ka pehu ʻana o nā kuʻekuʻe wāwae, nā wāwae, a me nā lima. | |
ʻAʻole i loko o kēia papa inoa nā hopena ʻaoʻao āpau. Inā loaʻa iā ʻoe kekahi mea ʻē, e kamaʻilio me kāu kauka e pili ana i ia mea.
Leka Lawe-Home
- He lāʻau lapaʻau ʻo Selpercatinib e kuhikuhi ana a hoʻopau i kahi protein kūikawā e pili ana i ka ulu ʻana o nā cell cancer.
- E lawe i ka lāʻau lapaʻau i ka manawa like i kēlā me kēia lā e like me ke kauoha a kāu kauka. Mai lawe pū me ka wai pomelo.
- E haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei (me nā huaora a me nā huahana lāʻau lapaʻau).
- ʻAʻole kūpono kēia lāʻau lapaʻau inā hāpai ʻoe, e hoʻāʻo ana e hāpai, a hānai waiū paha. He mea nui e hoʻohana nā wāhine a me nā kāne i ka kaohi hānau kūpono i ka wā o ka mālama ʻana a no hoʻokahi pule ma hope.
- Inā loaʻa iā ʻoe kekahi mau hopena koʻikoʻi e like me ka paʻakikī o ka hanu ʻana, ke kahe nui ʻana o ke koko, a i ʻole nā hōʻailona maʻi ʻaleka koʻikoʻi, e ʻimi koke i ke kōkua lapaʻau.
- Mai makaʻu e kamaʻilio me kāu kauka e pili ana i nā nīnau a hopohopo paha āu e loaʻa ai. E hoʻomanaʻo ʻaʻole ʻoe hoʻokahi.
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