He ʻala iʻa kou? E aʻo kākou e pili ana iā Trimethylaminuria (TMAU)!

I kekahi manawa i ko kākou ola, hiki mai nā mea kupanaha, ʻeā? Ua lohe paha ʻoe i kahi kūlana kahi e ʻala ai ke kino, ka hou, ka hanu, a i ʻole ka mimi o kekahi e like me ka iʻa pala? He leo kupanaha ia, ʻeā? Akā, aia maoli nō ia ʻano kūlana. ʻO kēia ke kūlana a kākou e kamaʻilio ai i kēia lā, ʻo Trimethylaminuria, a i ʻole `(TMAU)` no ka pōkole. Ua kapa pū kekahi poʻe iā ia he ``Fish Odor Syndrome``.

He aha ka trimethylaminuria (TMAU)?

I ka ʻōlelo maʻalahi, ʻo ka trimethylaminuria (TMAU) kahi maʻi metabolic . I kēia manawa ke noʻonoʻo nei paha ʻoe i ke ʻano o ka maʻi metabolic. I loko o ko mākou kino, nā kaʻina hana kemika, a i ʻole nā ​​​​kaʻina hana metabolic , e hana ʻia e hoʻololi i ka meaʻai a mākou e ʻai ai i ikehu a e hana i nā mea e pono ai ko mākou kino. Kōkua nā enzymes i loko o ko mākou kino i kēia mau kaʻina hana e hana pono. No laila, ma kēia kūlana i kapa ʻia ʻo trimethylaminuria, ma muli o ka loli o ka hana o kekahi enzyme, ʻaʻole hiki ke wāwahi pono ʻia kekahi o nā kemika i hana ʻia i loko o ke kino. ʻO ia ke kumu e puka mai ai kēlā ʻala iʻa maikaʻi ʻole mai ka hou, ka hanu, ka lawai, a me ka mimi.

Ua lohe paha ʻoe i nā kauka e kapa ana i kēia maʻi ʻo `(TMAU)` a i ʻole `(Fish Odor Syndrome)`. ʻAʻohe lāʻau lapaʻau piha no kēia . Akā, mai hopohopo. Hiki iā ʻoe ke hōʻemi i kēia mau hōʻailona i kahi nui ma ka hoʻololi ʻana i kāu meaʻai a inu ai, me ka hoʻohana ʻana i kekahi mau kopa a me nā lotion, a me ka mālama ʻana i kou kaumaha .

He aha nā ʻano nui o `(TMAU)`?

ʻElua mau ʻano nui o ka trimethylaminuria:

1. Trimethylaminuria mua : ʻO kēia ke ʻano hānau mua . ʻO ke ʻano kēia, ua hoʻokumu ʻia kēia ʻano e kekahi mau loli (`(Genetic mutations)`) i loko o nā genes (`(Genes)`) i hoʻoilina ʻia mai ka makuahine a me ka makuakāne.

2. Trimethylaminuria lua : Hana ʻia kēia ma hope o ke ola . Hiki ke hana ʻia kēia ʻala iʻa e kekahi mau kūlana olakino a i ʻole nā ​​​​mea hoʻohui meaʻai.

Pehea ka maʻamau o kēia ʻano?

ʻO ka ʻoiaʻiʻo, he ʻano laha ʻole ka TMAU. Hōʻike kekahi noiʻi e hoʻopilikia wale ia i hoʻokahi i loko o 200,000 a hoʻokahi miliona mau kānaka ma ka honua holoʻokoʻa. Eia nō naʻe, ua ʻōlelo ʻia hoʻi he ʻoi aku ka nui o ka loaʻa ʻana o nā wāhine ma mua o nā kāne.

Eia nō naʻe, manaʻo kekahi poʻe noiʻi he nui aku paha ka poʻe me ka `(TMAU)` i loko o ke kaiāulu ma mua o ka hōʻike ʻana o kēia mau helu. No ka mea , manaʻo ka poʻe he nui he pilikia kēia no ko lākou hoʻomaʻemaʻe pilikino . No laila, ʻaʻole lākou e haʻi aku i kekahi e pili ana i ia mea a hele paha e ʻike i ke kauka no ka hilahila. No laila, ʻaʻole lākou e loaʻa kahi hōʻailona (`(Diagnosis)`).

He aha nā hōʻailona o ka trimethylaminuria?

ʻO ka hōʻailona nui a maopopo loa, he ʻala iʻa mai ke kino, ka hanu, a me ka hou . I kekahi manawa, hiki i kēia ʻala ke lilo i mea ʻoluʻolu ʻole a hiki ke hoʻonāwaliwali. No kekahi poʻe, hiki ke hele pū me ka hanu ʻino (`(Halitosis)`) a me kahi ʻala ikaika mai ka mimi.

I kekahi manawa, ʻike nui ke kanaka me ka `(TMAU)` i kēia ʻala ke hou lākou a i ʻole ke kaumaha lākou. Eia nō naʻe, no kekahi poʻe, ikaika loa kēia ʻala a inā paha e komo lākou i loko o kahi lumi a lākou e noho ai, e kū ana ma ke alo o ke kūʻai ma kahi hale kūʻai, a e noho ana paha ma ka ʻaoʻao like o kahi kaʻa a kaʻaahi paha, hiki nō i kekahi ke honi iā ​​ia. E noʻonoʻo i ka paʻakikī o ia mea.

He aha nā kumu o ka `(TMAU)`?

Hana ʻia ka Trimethylaminuria i ka wā e hoʻopilikia ʻia ai ka hana o kahi enzyme i kapa ʻia ʻo `(FMO3)` i loko o ko mākou kino. ʻO `(FMO3)` ke kū nei no ka Flavin- containing monooxygenase 3. ʻO ka hana nui o kēia enzyme ka hoʻomalu ʻana i ka kemika i kapa ʻia ʻo `( Trimethylamine )` i hana ʻia i loko o ko mākou kino. ʻO kēia trimethylamine ke kumu o kēlā ʻala iʻa. Hana ʻia kēia trimethylamine i ka wā e ʻeli ʻia ai kekahi mau meaʻai a mākou e ʻai ai, no ka laʻana, ka iʻa, nā pīni, a me nā hua manu.

ʻO ka mea maʻamau e hana ʻia penei: Ke hōʻiliʻili ka trimethylamine i loko o ko kākou kino, hele mai ka enzyme `(FMO3)` a wāwahi iā ia, e hoʻolilo ana iā ia i kemika ʻala ʻole. A laila, ʻoiai e hele ana ia mai kā kākou ʻōnaehana hoʻoheheʻe i loko o ko kākou koko, ʻaʻole ia e honi.

Akā, he aha ka mea e hana ai inā ʻaʻole hana pono kēlā enzyme `(FMO3)`? Hōʻiliʻili kēlā trimethylamine pilau i loko o ko kākou kino. Ke hōʻiliʻili ʻia, puka mai ia i waho me ka hou, ka hanu, ka lawai, a me ka mimi, a puka mai kēlā ʻala iʻa. Maopopo iā ʻoe?

Loaʻa i ka poʻe me ka trimethylaminuria mua (`(Primary TMAU)`) kēia maʻi no ka mea ua hoʻoilina lākou i nā kope ʻano ʻē o nā genes e hana ana i ka enzyme `(FMO3)` (`(Abnormal FMO3 genes)`) mai ko lākou makuahine a me ko lākou makuakāne.

I loko o ka trimethylaminuria lua (`(Secondary TMAU)`), ʻaʻole hiki i kāu enzyme `(FMO3)` ke wāwahi i ka trimethylamine no kekahi kumu ʻē aʻe. Hiki ke hana ʻia kēia e:

• Inā loaʻa iā ʻoe kahi maʻi olakino, e like me ka hāʻule ʻana o ke akepaʻa a i ʻole ka maʻi hepatitis viral , hiki iā ia ke hoʻopilikia i ka hana a ka enzyme a pale iā ia mai ka wāwahi ʻana i ka trimethylamine.
• Inā ʻaʻole kaulike kou microbiome ʻōpū , ʻo ia hoʻi, aia kahi kaulike ʻole ma waena o nā bacteria maikaʻi a me nā bacteria maikaʻi ʻole i loko o kou ʻōpū, hiki i ka trimethylamine ke hōʻiliʻili nui. A laila, ʻaʻole hiki i ka enzyme (FMO3) ke hoʻopau i kēlā ʻala āpau.
• Inā ʻoe e lawe i nā mea hoʻopihapiha i loaʻa ka choline a i ʻole carnitine , kōkua kēia mau meaʻai i ka hoʻokumu ʻia ʻana o ka trimethylamine.

He aha nā pilikia o kēia maʻi?

Pehea e pili ai kahi kūlana i kapa ʻia ʻo trimethylaminuria i kou ola maikaʻi(`(ʻAno o ke ola)`) hiki ke hōʻino loa. Hōʻike ka noiʻi ʻana e pale pinepine ka poʻe me kēia maʻi i nā pilina, nā hana, a me nā hana kaiāulu no ka mea makaʻu lākou e ʻike kekahi poʻe i ke ʻala ʻino. Ma muli o kēia, hiki i ka poʻe me kēia maʻi ke loaʻa i nā pilikia olakino noʻonoʻo like ʻole. Eia kekahi laʻana:

• Hopohopo (`(Hopohopo)`)
• Kaumaha
• Hopohopo a me ka makaʻu kūpono ʻole (`(Paranoia)`)

ʻOiai he mea kakaikahi loa, ua hōʻike ʻia kekahi poʻe me TMAU he mau manaʻo pepehi kanaka (`(Suicidal behavior)`). Hōʻike kēia i ke koʻikoʻi o ka hopena noʻonoʻo o kēia ʻano.

Pehea e ʻike ʻia ai ka trimethylaminuria?

Hoʻoholo nā kauka i ka TMAU ma ke ana ʻana i ka nui o ka trimethylamine i loko o kou mimi. Hana pinepine ʻia kēia ma o kahi hoʻāʻo mimi . Eia kekahi, hiki i kāu kauka ke ʻōlelo aku i nā hoʻokolohua genetic e hoʻoholo ai inā loaʻa iā ʻoe ke ʻano mua (ʻo ia hoʻi, hānau ʻia) a i ʻole ke ʻano lua (ʻo ia hoʻi, loaʻa).

He aha nā lāʻau lapaʻau no ka trimethylaminuria?

Hiki i kāu kauka ke ʻōlelo aku i nā mea like ʻole e kōkua i ka hōʻemi ʻana i nā hōʻailona o TMAU.

• ʻAi: Manaʻo ʻia e hoʻopau i kekahi mau meaʻai e hoʻonui ai i ka hana ʻana o ke kino i ka kemika e hoʻoulu ai i ke kūlana (TMAU).
• Nā kopa a me nā lotion kūikawā: Manaʻo ʻia e hoʻohana i nā kopa a me nā lotion kūikawā e kōkua i ka hōʻemi ʻana i ke ʻala iʻa mai ka ʻili.
• Nā lāʻau lapaʻau: I kekahi manawa hiki ke kuhikuhi ʻia nā lāʻau lapaʻau.
• Kākoʻo olakino noʻonoʻo: Hiki ke aʻo ʻia ʻoe e ʻimi i ka ʻōlelo aʻoaʻo noʻonoʻo e kōkua iā ʻoe e hoʻomanawanui i ke kaumaha i hoʻokumu ʻia e kēia ʻano.

He aha nā ʻano meaʻai e pono e hoʻopau ʻia?

Inā loaʻa iā ʻoe ka trimethylaminuria, haʻi pinepine nā kauka iā ʻoe e kaupalena a hōʻalo loa paha i nā meaʻai aʻe:

• Iʻa a me nā meaʻai kai ʻē aʻe (ʻoi aku ka iʻa paʻakai)
• Nā hua manu (ʻoi aku hoʻi nā yolks hua manu)
• ʻAkepaʻa a me nā ʻōpū o loko o nā holoholona ʻē aʻe
• Nā legumes e like me ka soybeans, chickpeas, a me nā lentils
• Nā mea kanu Cruciferous e like me ka kāpeti, broccoli, cauliflower, a me nā ʻōpuʻu Brussels
• Pīnati
• Waiū a me nā huahana waiū (no kekahi)
• ʻO nā meaʻai a me nā mea hoʻopihapiha meaʻai waiwai i ka choline a me L-carnitine

He mea nui: ʻAʻole pono nā kānaka a pau e hoʻopau i kēia mau meaʻai a pau. ʻOi aku ka maikaʻi o ke kamaʻilio ʻana me ke kauka a meaʻai meaʻai paha e hoʻoholo ai i nā meaʻai kūpono iā ʻoe.

He aha nā lāʻau lapaʻau i hāʻawi ʻia no ka `(TMAU)`?

Hiki i kāu kauka ke kuhikuhi i nā lāʻau lapaʻau e like me kēia e hōʻemi i nā hōʻailona o TMAU:

• Nā lāʻau antibiotics a me nā probiotics : Kōkua kēia mau lāʻau lapaʻau i ka hōʻemi ʻana i ka nui o nā bacteria i loko o kou ʻōpū, a laila e hōʻemi ana i ka hana ʻana o ka trimethylamine.
• ʻAlahu i hoʻāla ʻia : Ua like kēia me ka huʻa. Hoʻopili ia i ka trimethylamine i loko o ke kino a kōkua iā ia e hoʻokuʻu ʻia i loko o ka ʻōpala.
• Nā lāʻau antidepressants a me nā lāʻau anti-anxiety : Hāʻawi ʻia kēia mau lāʻau lapaʻau e mālama i nā pilikia olakino noʻonoʻo e kū nei i kekahi poʻe me TMAU.

Hiki i kāu kauka ke kuhikuhi iā ʻoe i ke kākoʻo olakino noʻonoʻo . He mea nui loa ke kamaʻilio ʻana me kahi psychologist a kākāʻōlelo paha inā ʻoe e hakakā nei me ka manaʻo ponoʻī a me nā pilikia kiʻi kino. Hiki i ka Psychotherapy ke kōkua iā ʻoe e aʻo pehea e hoʻoponopono ai i kou kūlana a hoʻokele i ke kaumaha.

He aha ka mea e hiki ai i kekahi me ka trimethylaminuria ke manaʻo?

He maʻi mau loa ʻo Trimethylaminuria. ʻO ia hoʻi, ʻaʻole hiki ke ho'ōla piha ʻia a hoʻomaikaʻi paha iā ia iho. Eia nō naʻe, e like me ka mea i ʻōlelo ʻia ma mua, aia nā lāʻau lapaʻau a me nā mea hiki iā ʻoe ke hana e hōʻemi i nā hōʻailona o TMAU a hoʻemi i ka hopena o ke ʻano i kou ola.

Pehea wau e mālama ai iaʻu iho?

He mea nui loa ka mālama ponoʻī i ka wā e noho pū ana me TMAU. Eia kekahi mau mea e noʻonoʻo ai:

• Hoʻomaʻemaʻe pilikino : ʻO ka hoʻohana ʻana i nā kopa a me nā lotion me ka waiwai `(pH)` haʻahaʻa e hiki ke kōkua i ka hōʻemi ʻana i kou ʻala kino. E nīnau i kāu kauka i ka waiwai `(pH)` kūpono iā ʻoe a me nā huahana maikaʻi loa.
• E makaʻala i kāu meaʻai : Hiki i nā meaʻai he nui ke hoʻonui i ka trimethylaminuria. E kamaʻilio me kahi meaʻai meaʻai e hoʻolālā i kāu mau meaʻai a me nā koho meaʻai i loaʻa iā ʻoe nā meaola āu e pono ai.
• E hoʻokele i ke kaumaha : Hiki i ka hoʻonui ʻia o ke kaumaha ke hoʻonui i nā hōʻailona o TMAU. No laila, e nīnau i kāu kauka e pili ana i nā ala e kōkua ai i ka hōʻemi ʻana i kou pae kaumaha. (e laʻa, ka noʻonoʻo ʻana, ka yoga, nā hoʻomaʻamaʻa hanu)
• E huli i ke kākoʻo : He maʻi laha ʻole ʻo Trimethylaminuria, no laila hiki iā ʻoe ke manaʻo mehameha a mehameha. No laila, hiki ke lilo i mea kōkua nui ka hoʻopili ʻana me nā hui kākoʻo kahi e loaʻa ai nā poʻe ʻē aʻe me ke ʻano like .

Āhea wau e ʻike ai i kaʻu kauka?

Inā ʻaʻole e hoʻomaikaʻi kāu mau hōʻailona ma hope o ka hoʻololi ʻana i kāu meaʻai a me ka hoʻokele kaumaha, e ʻike pono i kāu kauka. Hiki iā ia ke kūkākūkā i nā koho lapaʻau ʻē aʻe āu e noʻonoʻo ai.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

No ka mea, he ʻano maʻamau ʻole ka trimethylaminuria, ʻaʻole paha ʻoe i ʻike nui e pili ana i ia mea. Eia kekahi mau nīnau hiki iā ʻoe ke nīnau i kāu kauka:

• No ke aha lā wau i komo ai i loko o kēia kūlana?
• He aha nā lāʻau lapaʻau maikaʻi loa āu e ʻōlelo mai nei noʻu?
• Hiki iā ʻoe ke kuhikuhi mai i kahi hui kākoʻo a papahana paha kahi e hiki ai iaʻu ke loaʻa ke kōkua?

Hiki i nā poʻe me ka trimethylaminuria ke honi iā ​​lākou iho?

He pilikia nō hoʻi kēia no nā kānaka he nui. ʻAe, honi pinepine mākou i ko mākou hou a me ke ʻala o ke kino, a hiki i ka poʻe me ka `(TMAU)` ke honi i ko lākou ʻala ponoʻī. Eia naʻe, i kekahi manawa, ke maʻa lākou i ko lākou ʻala ponoʻī, ʻaʻole paha lākou e ʻike ikaika e like me ka poʻe ʻē aʻe. Eia kekahi, ʻaʻole hiki i nā kānaka a pau ke ʻōlelo ʻaʻole lākou e honi; ʻaʻole paha e ʻike kekahi poʻe he ʻala ʻē ko ko lākou kino.

ʻO ka mea hope loa, ʻo ka leka koʻikoʻi loa

ʻO Trimethylaminuria kahi maʻi e hiki ai i ke kanaka ke hoʻolilo i ke kanaka i mea kōkua ʻole, ʻaʻole wale i ke kino, akā i ka noʻonoʻo hoʻi . ʻOiai inā ʻaʻole ia e hōʻeha kino, hiki iā ia ke hōʻeha nui a me ka ʻeha i ka noʻonoʻo. Hoʻokaʻawale kekahi poʻe me kēia maʻi iā lākou iho mai ke kaiāulu a hoʻāʻo e noho kaʻawale, me ka makaʻu e lilo lākou i mea hoʻonāukiuki i nā poʻe ʻē aʻe. ʻOiai ma hope o ka hoʻololi ʻana i kā lākou ʻai a me ka hahai ʻana i nā ʻōlelo aʻoaʻo ʻē aʻe, manaʻo kekahi poʻe me `(TMAU)` e pono nō lākou e mālama i ko lākou ola mai nā poʻe ʻē aʻe. Hiki i kēia ʻano kaʻawale kaiapili ke hoʻoulu iā ʻoe e hoʻomohala i nā mea e like me ke kaumaha a me ka hopohopo.

E hoʻomanaʻo, ʻaʻole ʻoe hoʻokahi . Inā ʻoe e ʻeha nei i kēia maʻi, mai hilahila a makaʻu paha e noi i kāu kauka no ke kōkua. Hiki iā lākou ke hoʻomaopopo i kāu mea e hele nei a hiki ke haʻi iā ʻoe e pili ana i nā papahana a me nā lawelawe e hiki ke kōkua iā ʻoe. He mea nui kou olakino noʻonoʻo e like me kou olakino kino. No laila e noʻonoʻo pono hoʻi.

ʻtrimethylaminuria , maʻi ʻala iʻa, maʻi ʻala iʻa, ʻala kino, nā maʻi metabolic, ka enzyme FMO3, trimethylamine