Koj puas cia li tsaug zog thaum nruab hnub? Qhov no tej zaum yuav yog (Narcolepsy)! Cia peb tham txog qhov no

Koj puas tau muaj ib zaug uas koj xav tias koj tsaug zog tsis taus thaum koj ua haujlwm thaum nruab hnub lossis tham nrog cov phooj ywg? Tej zaum koj yuav xav tias, "Auj... kuv tsis tau pw tsaug zog txaus hmo tas los." Tab sis nws tsis yog ib qho teeb meem ntawm kev qaug zog xwb. Hnub no peb yuav tham txog ib hom teeb meem pw tsaug zog txawv me ntsis. Qhov ntawd yog ib yam mob hu ua Narcolepsy . Txawm hais tias nws tsis tshua muaj, nws yog ib yam dab tsi uas ntau tus neeg tau hnov ​​​​​​txog vim yog cov tsos mob cuam tshuam nrog nws . Nws tuaj yeem kho tau, tab sis nws tuaj yeem muaj kev cuam tshuam loj rau koj lub neej, kev ua haujlwm, thiab kev sib raug zoo hauv zej zog.

Narcolepsy yog dab tsi?

Hais yooj yim xwb, Narcolepsy yog ib yam mob ntawm lub paj hlwb uas ua rau koj tsaug zog sai sai thiab tsis tuaj yeem tswj tau thaum nruab hnub. Qhov tshwj xeeb, koj lub hlwb tsis tuaj yeem tswj kev pw tsaug zog thiab kev sawv. Qhov no tuaj yeem ua rau koj tsaug zog ntau dhau thaum nruab hnub, txawm tias koj pw tsaug zog npaum li cas thaum hmo ntuj los xij.

Cov tsos mob tseem ceeb ntawm Narcolepsy yog dab tsi?

Muaj plaub yam tsos mob tseem ceeb ntawm tus kab mob Narcolepsy. Tab sis feem ntau cov neeg tsis muaj tag nrho plaub yam no ib zaug. Tej zaum ib txhia neeg yuav muaj ib lossis ob yam. Cia peb saib seb cov tsos mob no yog dab tsi.

• Pw tsaug zog ntau dhau thaum nruab hnub : Qhov no yog ib qho tsos mob ntawm Narcolepsy. Nws zoo li muaj "kev pw tsaug zog nres" uas koj cia li tsaug zog. Txawm koj ua dab tsi los xij, koj xav nres thiab mus pw.
• Cataplexy: Qhov no yog qhov poob ntawm kev tswj cov leeg nqaij tam sim ntawd . Qee zaum nws tuaj yeem tsis hnyav heev, zoo li kev co ntawm cov leeg nqaij ntawm ib sab ntawm lub ntsej muag lossis caj dab. Yog tias nws hnyav heev, koj tuaj yeem poob rau hauv av tam sim ntawd. Cia peb tham txog qhov no kom ntxaws ntxiv.
• Kev pom kev tsis meej pem ntsig txog kev pw tsaug zog : Cov no yog kev pom kev tsis meej pem uas tshwm sim thaum koj tsaug zog lossis thaum koj tab tom yuav sawv, thiab lawv tuaj yeem ua rau ntshai heev.
• Kev Pw Tsaug Zog Tuag Tes Tuag Taw : Tej zaum koj yuav tau hnov ​​​​​​txog qhov no tias "ntshai hauv npau suav thiab tsis tuaj yeem txav mus los" lossis raws li qee tus hais tias, "xav tias zoo li dab tau nce mus." Qhov no yog thaum koj tsis tuaj yeem txav koj lub cev txawm tias thaum koj sawv los, lossis tej zaum tsis tau tsim tag nrho. Cia peb saib qhov no ntxiv me ntsis.

Me ntsis ntxiv txog (Cataplexy)

Peb tau hais ua ntej lawm tias cataplexy yog qhov poob ntawm cov leeg nqaij tam sim ntawd. Narcolepsy muab faib ua ob hom tseem ceeb nyob ntawm seb puas muaj cov tsos mob cataplexy no:

• (Hom Narcolepsy 1) : Hom no muaj cov tsos mob ntawm (Cataplexy) . Kwv yees li 20% ntawm cov neeg mob (Narcolepsy) yog hom no.
• (Narcolepsy Hom 2) : Hom no tsis muaj tsos mob ntawm (Cataplexy) . Feem ntau, uas yog, kwv yees li 80%, poob rau hauv hom no.

Feem ntau, thaum peb pw tsaug zog, peb lub hlwb feem ntau tsis tswj peb cov leeg nqaij kom peb tsis ua raws li peb txoj kev npau suav. Cov neeg uas muaj cataplexy yuav muaj kev poob leeg nqaij sai sai, zoo ib yam li qhov uas tau ntsib thaum lub sijhawm pw tsaug zog REM, txawm tias thaum lawv tseem sawv los.

Hauv cov mob me me, cataplexy tsuas yog cuam tshuam rau cov leeg ntawm lub ntsej muag thiab caj dab - piv txwv li, lub puab tsaig yuav poob qis. Los yog nws tsuas yog cuam tshuam rau ib sab ntawm lub cev xwb. Hauv cov mob hnyav, cataplexy tuaj yeem ua rau lub cev vau tam sim ntawd, uas tuaj yeem ua rau tuag taus. Cov mob no feem ntau kav ntev li ob peb feeb, tab sis koj yuav tsis tuaj yeem hais lus lossis txav mus los thaum lub sijhawm no.

Lwm yam tshwj xeeb txog cataplexy yog tias nws tuaj yeem tshwm sim los ntawm qee yam kev xav . Nws tuaj yeem tshwm sim tshwj xeeb tshaj yog thaum koj zoo siab, luag, lossis tso dag. Nws kuj tseem tuaj yeem tshwm sim thaum koj xav tsis thoob, ntshai, lossis npau taws, tab sis nws tsis tshua muaj.

Cataplexy yuav zoo li txawv me ntsis rau cov menyuam yaus thiab cov neeg uas muaj li rau lub hlis thaum cov tsos mob thawj zaug tshwm sim. Lawv yuav ua ntsej muag tsis zoo, taw lawv tus nplaig tawm, lossis cov leeg nqaij tsis muaj zog uas tsis muaj feem cuam tshuam rau kev xav.

Me ntsis ntxiv txog kev pw tsaug zog tuag tes tuag taw

Thaum peb pw tsaug zog, lub hlwb tsis tswj peb cov leeg nqaij kom lawv tsis ua raws li peb pom hauv peb txoj kev npau suav. Tab sis thaum peb sawv, qhov kev tswj no yuav tsum ua haujlwm kom zoo dua. Tab sis yog tias koj muaj kev pw tsaug zog tuag tes tuag taw, koj lub cev tsis tau txais qhov kev tswj cov leeg nqaij ntawd rov qab. Koj tuaj yeem ua pa thiab txav koj lub qhov muag, tab sis koj tsis tuaj yeem tham lossis txav lwm qhov ntawm koj lub cev.

Kev pom kev tsis tseeb feem ntau tshwm sim thaum lub sijhawm pw tsaug zog tuag tes tuag taw. Lawv tuaj yeem pom tseeb heev, qee zaum ua rau ntshai heev. Zoo hmoo, kev pw tsaug zog tuag tes tuag taw feem ntau kav ntev li ob peb feeb (txawm hais tias nws tuaj yeem zoo li ntev heev rau tus neeg uas muaj nws).

Puas muaj lwm yam tsos mob?

Ntxiv rau plaub yam tsos mob tseem ceeb, cov neeg uas muaj tus kab mob narcolepsy kuj yuav muaj lwm yam tsos mob thiab tus cwj pwm. Ib txhia ntawm lawv suav nrog:

• Kev Txav Mus Los Tsis Siv Neeg : Cov neeg uas muaj tus kab mob narcolepsy tej zaum yuav txuas ntxiv txav mus los ntawm lub cev, xws li lawv txhais tes, txawm tias thaum lawv tsaug zog los xij.
• Kev Nco Qab lossis Kev Tsis Nco Qab : Nws yog ib qho uas cov neeg no feem ntau tsis nco qab lawv tau ua dab tsi ua ntej mus pw.
• Kev hais lus sai sai thaum pw tsaug zog : Ib tug neeg uas muaj tus kab mob narcolepsy yuav hais ib yam dab tsi tam sim ntawd (feem ntau tsis muaj tseeb lossis tsis muaj feem cuam tshuam rau lub sijhawm ntawd). Thaum qhov no tshwm sim, lawv yuav sawv rov los tag nrho. Tab sis lawv feem ntau tsis nco qab nws.

Leej twg muaj mob narcolepsy? Nws tshwm sim ntau npaum li cas?

Feem ntau cov kws kho mob kuaj pom tias muaj tus mob narcolepsy rau cov neeg hnub nyoog ntawm 5 thiab 50 xyoo. Txawm li cas los xij, nws feem ntau tshwm sim rau cov tub ntxhais hluas , ntawm hnub nyoog 18 thiab 25 xyoo. Cov txiv neej muaj feem yuav mob no ntau dua.

Narcolepsy tsis yog ib qho mob uas tshwm sim ntau heev.Kev tshawb fawb qhia tau tias muaj li ntawm 25 txog 50 tus neeg ntawm txhua 100,000 tus neeg thoob ntiaj teb muaj tus kab mob no. Txawm li cas los xij, vim tias nws siv sijhawm ntau xyoo los kuaj pom tus kab mob, nws nyuaj rau hais tias muaj pes tsawg tus neeg muaj tus kab mob no tiag.

Narcolepsy cuam tshuam li cas rau kuv lub cev?

Yuav kom nkag siab txog tus mob narcolepsy, nws yuav pab tau yog paub me ntsis txog peb txoj kev pw tsaug zog ua haujlwm li cas. Muaj ntau theem tseem ceeb ntawm peb txoj kev pw tsaug zog:

• Theem 1: Pw tsaug zog me ntsis . Qhov no yog theem luv luv. Nws pib thaum koj tsaug zog. Nws suav txog li 5% ntawm koj tag nrho kev pw tsaug zog.
• Theem 2: Pw tsaug zog tob . Qhov no tob me ntsis. Nws yog li ntawm 45%-50% ntawm tag nrho cov kev pw tsaug zog (qhov no nce ntxiv thaum peb laus zuj zus).
• Theem 3: Pw tsaug zog qeeb qeeb . Kwv yees li 25% ntawm tag nrho cov kev pw tsaug zog (qhov no yuav txo qis thaum muaj hnub nyoog). Nws nyuaj heev rau tsa ib tus neeg sawv hauv theem no. Yog tias koj tsa lawv sawv tam sim ntawd, lawv yuav mus rau hauv lub xeev tsis meej pem hu ua "sleep inertia". Kev taug kev pw tsaug zog thiab kev tham lus pw tsaug zog kuj tshwm sim hauv theem no.
• (REM) Pw tsaug zog : (REM) sawv cev rau (Rapid Eye Movement) , uas txhais tau tias lub qhov muag txav mus sai. Nws yog thaum lub sijhawm no uas peb npau suav. Thaum ib tug neeg pw tsaug zog (REM), koj tuaj yeem pom lub qhov muag txav mus rau hauv qab lub qhov muag.

Yog koj tsis muaj mob narcolepsy, thaum koj mus pw tsaug zog, koj pib theem 1, tom qab ntawd mus rau theem 2 thiab 3. Koj ncig ntawm cov theem no, thiab thaum kawg nkag mus rau REM pw tsaug zog, qhov chaw koj pib npau suav. Tom qab thawj lub voj voog REM, koj pib lub voj voog tshiab thiab rov qab mus rau theem 1 lossis 2. Ib lub voj voog feem ntau kav li 90 feeb. Cov neeg feem coob mus txog plaub txog tsib lub voj voog ib hmos (yog tias lawv pw tsaug zog rau 8 teev).

Tab sis yog tias koj muaj tus mob narcolepsy, koj lub voj voog pw tsaug zog tsis tshwm sim li ntawd. Hloov chaw, koj mus rau hauv REM pw tsaug zog yuav luag sai li sai tau thaum koj tsaug zog . Thoob plaws hmo ntuj, koj pw tsaug zog luv luv, feem ntau tsis ua tiav lub voj voog pw tsaug zog ib txwm muaj.

Hauv tus mob narcolepsy, txawm koj pw tsaug zog zoo li cas thaum hmo ntuj los xij, koj yuav xav tias koj tsaug zog tsis taus thaum nruab hnub. Nws nyuaj heev rau koj tsum tsis txhob pw tsaug zog. Tab sis qhov kev pw tsaug zog no uas los thaum nruab hnub kuj luv luv (kwv yees li 15-30 feeb). Thaum koj sawv, koj xav tias koj tshiab thiab npaj txhij ua qhov koj tau ua ua ntej dua. Txawm li cas los xij, vim qhov no tshwm sim ntau zaus hauv ib hnub uas narcolepsy ua rau koj lub neej tsis zoo.

Dab tsi yog cov ua rau mob narcolepsy?

Cov ua rau mob narcolepsy sib txawv nyob ntawm hom mob narcolepsy uas koj muaj, tab sis lawv txhua tus cuam tshuam nrog thaj chaw tshwj xeeb ntawm koj lub hlwb hu ua hypothalamus , uas tswj kev pw tsaug zog thiab kev sawv.

Ua rau (Hom 1 Narcolepsy)

Xyoo 1998, cov kws tshawb nrhiav tau tshawb pom ib yam tshuaj hu ua orexins (qee zaum hu ua hypocretins) . Cov no yog siv los ntawm qee cov neurons (cov hlwb hlwb) los xa cov lus. Cov neurons uas siv orexins nyob hauv ib feem ntawm lub hlwb hu ua hypothalamus. Cov neurons no yog cov uas feem ntau pab kom peb tsaug zog.

Cov theem Orexin feem ntau pom muaj nyob rau hauv cov kua dej cerebrospinal (CSF) - cov txheej nyias nyias uas nyob ib puag ncig lub hlwb thiab tus txha caj qaum. Txawm li cas los xij, rau cov neeg uas muaj narcolepsy, cov theem orexin hauv CSF qis heev lossis tsis pom. Qhov no txhais tau tias cov hlwb uas ua orexin tau tso tseg ua haujlwm lossis tau raug rhuav tshem los ntawm ib yam dab tsi.

Lwm cov kev tshawb fawb qhia tias qhov laj thawj uas cov neurons no tsis ua haujlwm feem ntau yog qhov teeb meem autoimmune . Qhov no txhais tau tias koj lub cev lub cev tiv thaiv kab mob tawm tsam cov neurons uas tsim thiab siv orexin, lossis orexin nws tus kheej, lossis ob qho tib si.

Kwv yees li ntawm 90% -95% ntawm cov neeg uas muaj tus kab mob Narcolepsy Hom 1 muaj kev hloov pauv tshwj xeeb uas cuam tshuam rau lawv lub cev tiv thaiv kab mob (uas yog HLA-DQB1*06:02 ). Txawm li cas los xij, kwv yees li ntawm 25% ntawm cov pej xeem feem ntau kuj muaj qhov kev hloov pauv no tab sis tsis muaj Narcolepsy. Yog li ntawd, cov kws tshaj lij tsis kuaj qhov kev hloov pauv no, thiab lawv tsis paub meej tias nws ua lub luag haujlwm dab tsi. Kuj tseem muaj qee qhov pov thawj tias tus mob no tuaj yeem khiav hauv tsev neeg. Yog tias ib tug txheeb ze thawj zaug (niam txiv, kwv tij neej tsa, menyuam) muaj Narcolepsy, koj muaj feem yuav mob nws thiab.

Txawm li cas los xij, tus kab mob Narcolepsy Hom 1 kuj tseem tuaj yeem tshwm sim tom qab qee yam kab mob viral thiab bacterial, tshwj xeeb tshaj yog cov kab mob influenza xws li H1N1 influenza thiab cov kab mob uas ua rau mob caj pas. Cov kws tshaj lij ntseeg tias qhov no yuav yog vim tias cov kab mob qee zaum tuaj yeem ua rau muaj kev hloov pauv thiab ua haujlwm tsis zoo hauv lub cev tiv thaiv kab mob.

Ua rau (Hom 2 Narcolepsy)

Txawm hais tias muaj ntau yam paub txog qhov ua rau muaj tus kab mob Narcolepsy Hom 1, tsis muaj ntau yam txog tus kab mob Narcolepsy Hom 2. Cov kws tshaj lij tseem tsis tau nkag siab tag nrho tias vim li cas tus kab mob Narcolepsy Hom 2 thiaj tshwm sim. Tab sis lawv xav tias nws yuav muaj cov laj thawj zoo sib xws. Piv txwv li, nws yuav yog vim muaj kev puas tsuaj tsawg dua rau cov neurons uas siv orexin, lossis teeb meem nrog txoj kev uas orexin mus ncig hauv lub hlwb.

Kev mob Narcolepsy theem ob

Muaj tej yam tsawg tsawg uas ua rau koj lub hlwb tsis ua haujlwm zoo (narcolepsy) kuj ua rau koj lub hlwb puas. Qhov kev puas tsuaj no kuj ua rau koj lub hlwb tsis ua haujlwm zoo (concussions), raug mob hlwb (traumatic brain injuries), mob hlwb (stroke), thiab mob qog hauv hlwb.

Kev qaug zog kuj tseem yog ib qho tsos mob ntawm lwm yam mob uas koj tau txais los ntawm niam txiv. Piv txwv li:

• (Autosomal Dominant Cerebellar Ataxia, Narcolepsy thiab Lag Ntseg (ADCADN))
• (Autosomal Dominant Narcolepsy, Hom 2 Ntshav Qab Zib thiab Kev Rog Dhau)

Puas yog Narcolepsy kis tau?

Tsis yog, tus kab mob Narcolepsy tsis yog ib yam kab mob sib kis tau. Koj yuav kis tsis tau los ntawm lwm tus, thiab lwm tus yuav kis tsis tau los ntawm koj.

Yuav ua li cas thiaj paub tias mob narcolepsy yog dab tsi?

Koj cov tsos mob yuav ua rau tus kws kho mob xav tias koj muaj tus kab mob narcolepsy. Txawm li cas los xij, cov tsos mob ntawm tus kab mob narcolepsy zoo ib yam li lwm yam kab mob hauv lub hlwb thiab kev pw tsaug zog. Yog li ntawd, nws yog ib qho tseem ceeb kom paub seb koj puas muaj tus kab mob narcolepsy.Kev kuaj mob tseeb tsuas yog ua tau los ntawm kev kuaj mob tshwj xeeb xwb.

Ua ntej ua ntau yam kev kuaj mob tseem ceeb rau narcolepsy, tus kws kho mob yuav xub xyuas seb koj puas tau pw tsaug zog txaus. Qhov no feem ntau ua tiav los ntawm kev siv cov txheej txheem yooj yim uas saib xyuas koj cov qauv pw tsaug zog. Ib qho piv txwv yog actigraphy . Qhov no suav nrog kev siv lub cuab yeej, xws li lub moos tes, los saib xyuas koj cov qauv txav mus los (xws li thaum koj pw tsaug zog thiab thaum koj sawv thiab txav mus los).

Cov kev kuaj twg siv los kuaj mob narcolepsy?

Muaj ntau yam kev kuaj mob uas ua tau los kuaj mob narcolepsy:

• Kev Kawm Txog Kev Pw Tsaug Zog ((Kev Kawm Txog Kev Pw Tsaug Zog - Polysomnogram)) : Qhov kev xeem no siv ntau yam sensors los saib xyuas seb koj pw tsaug zog li cas. Qhov tseem ceeb tshaj plaws hauv kev kawm txog kev pw tsaug zog tag nrho, uas yog, polysomnogram ((Polysomnogram)) yog siv (EEG) sensors . Cov sensors no saib xyuas koj lub hlwb nthwv dej ((Brain Waves)). Qhov no tso cai rau cov kws kho mob pom tias koj pw tsaug zog theem twg hauv feeb txhua feeb. Cov neeg uas muaj (Narcolepsy) pw tsaug zog (REM) sai dua li cov neeg ib txwm, yog li qhov kev xeem no tuaj yeem ntes tau nws. Nws kuj sau cov sijhawm thaum lawv sawv hauv nruab nrab ntawm lawv txoj kev pw tsaug zog. Lwm qhov laj thawj vim li cas qhov kev xeem no tseem ceeb yog tias kev pw tsaug zog ntau dhau thaum nruab hnub kuj tuaj yeem yog ib qho tsos mob ntawm tus mob hu ua pw tsaug zog apnea ((Sleep Apnea)) . Kev kawm txog kev pw tsaug zog tuaj yeem lees paub tias koj tsis muaj pw tsaug zog apnea.
• Kev Ntsuas Kev Pw Tsaug Zog Ntau Zaug (MSLT) : Qhov kev ntsuas no ntsuas seb koj tsaug zog tau yooj yim npaum li cas thaum nruab hnub. Nws suav nrog kev pw tsaug zog ntau zaus hauv ib lub sijhawm tshwj xeeb. Nws tuaj yeem txiav txim siab seb koj puas tsaug zog ntau dhau thaum nruab hnub. Qhov no yog ib qho tsos mob ntawm tus mob narcolepsy. Nws feem ntau ua rau hnub tom qab kev kawm txog kev pw tsaug zog thaum hmo ntuj.
• Kev Ntsuas Kev Ua Kom Sawv Ntsug : Qhov kev ntsuas no ntsuas seb koj tuaj yeem ua kom tsaug zog zoo li cas thaum nruab hnub, txawm tias thaum koj yooj yim tsaug zog los xij. Nws tsis yog siv los kuaj mob narcolepsy, tab sis nws tuaj yeem pab tshem tawm lwm yam teeb meem. Nws kuj tseem muaj txiaj ntsig zoo los saib seb cov tshuaj txhawb zog puas ua haujlwm.
• Kev Ntsuas Pob Txha (Kev Ntsuas Lumbar) : Qhov kev kuaj no tuaj yeem ntes tau cov orexin qis hauv koj cov kua dej cerebrospinal (CSF). Qhov no yog ib txoj hauv kev tseem ceeb los kuaj mob Narcolepsy Hom 1. Cov orexin qis tuaj yeem yog ib qho cim qhia tias ib tus neeg uas muaj Narcolepsy tseem tsis tau muaj cataplexy, tab sis tej zaum yuav yog ib qho cim qhia tias lawv yuav tsim cataplexy yav tom ntej. Txawm li cas los xij, vim tias cov orexin tsis hloov pauv rau cov neeg uas muaj Narcolepsy Hom 2, qhov no tsis yog ib txwm yog kev kuaj mob.

Lwm yam kev ntsuam xyuas

Cov neeg uas muaj tus kab mob narcolepsy yuav muaj ntau yam kev kuaj mob ntxiv. Piv txwv li, yog tias koj muaj tus kab mob cataplexy, nws yuav zoo ib yam li cov tsos mob ntsig txog kev txav mus los ntawm lwm yam teeb meem hauv lub hlwb, xws li qaug dab peg. Yog li ntawd, cov kws kho mob yuav kuaj ua ntej rau cov mob hnyav dua, xws li qaug dab peg. Yog li ntawd, nws yuav siv sijhawm ntev los kuaj mob narcolepsy. Koj tus kws kho mob yog tus neeg zoo tshaj plaws los piav qhia seb koj xav tau kev kuaj mob dab tsi thiab vim li cas lawv thiaj ua.

Yuav kho tus mob narcolepsy li cas? Puas kho tau?

Kab mob Narcolepsy kho tau, tab sis nws tsis tuaj yeem kho tau . Kev kho mob feem ntau pib nrog tshuaj. Tab sis kev hloov pauv rau koj txoj kev ua neej niaj hnub thiab kev ua neej nyob kuj tuaj yeem pab tau. Kab mob Narcolepsy feem ntau teb tau zoo rau kev kho mob. Qhov no tuaj yeem pab txwv qhov kev cuam tshuam los ntawm cov tsos mob.

Nco ntsoov, narcolepsy yog ib qho mob uas yuav kav ntev mus ib txhis, tab sis nws tsis hnyav zuj zus tuaj.

Cov tshuaj twg yog cov tshuaj rau narcolepsy?

Tshuaj yog kev kho mob tseem ceeb rau narcolepsy. Feem ntau cov tshuaj yog rau kev tsaug zog ntau dhau thaum nruab hnub. Txawm li cas los xij, qee cov tshuaj kuj cuam tshuam rau lwm cov tsos mob. Nov yog qee hom tshuaj uas tuaj yeem muab rau tus mob no:

• Cov Tshuaj Pab Kom Sawv Ntsug : Cov no feem ntau yog thawj cov kev kho mob. Piv txwv li suav nrog Modafinil thiab Armodafinil . Cov tshuaj no ua rau koj lub paj hlwb ua haujlwm zoo. Qhov no tuaj yeem pab txo qhov hnyav thiab zaus ntawm kev tsaug zog thaum nruab hnub.
• Cov tshuaj Amphetamines thiab cov tshuaj ua kom lub siab zoo li Amphetamine : Cov tshuaj xws li methylphenidate (paub nyob rau hauv cov npe lag luam Ritalin®, Concerta®, Qullivant®) thiab amphetamine/dextroamphetamine ua ke (paub nyob rau hauv lub npe lag luam Adderall®).
• Cov Tshuaj Tiv Thaiv Kev Nyuaj Siab : Cov no suav nrog Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) (piv txwv li Venlafaxine - hu ua Effexor®), Selective Serotonin Reuptake Inhibitors (SSRIs) (piv txwv li Fluoxetine - hu ua Prozac®), lossis Tricyclic Antidepressants (piv txwv li Clomipramine lossis Protriptyline - cov no tam sim no tsis tshua siv).
• (Sodium Oxybate) : Cov tshuaj no pab koj tsaug zog zoo dua thiab txo qhov zaus ntawm (Cataplexy). Vim yog cov teebmeem ntawm cov tshuaj no, nws raug tswj hwm nruj me ntsis hauv ntau lub tebchaws. Txawm li cas los xij, nws feem ntau siv los kho (Hom 1 Narcolepsy).
• Cov tshuaj uas cuam tshuam rau histamine : Ib qho piv txwv ntawm cov tshuaj zoo li no yog Pitolisant.Qhov no yog ib qho tshuaj tiv thaiv histamine receptor. Cov tshuaj tiv thaiv receptor yog cov tshuaj uas tiv thaiv qee cov tshuaj hauv koj lub cev kom tsis txhob lo rau cov cell. Qhov no txo ​​lossis tiv thaiv cov cell kom tsis txhob ua qee yam.

Txawm hais tias muaj ntau txoj kev kho mob rau cov neeg laus (narcolepsy), cov kev kho mob rau cov menyuam yaus muaj tsawg heev. Koj tus menyuam tus kws kho mob menyuam yaus lossis tus kws tshwj xeeb tuaj yeem qhia koj zoo tshaj plaws txog cov kev kho mob twg rau koj thiab lawv pom zoo li cas.

Cov teeb meem/cov kev mob tshwm sim ntawm kev kho mob

Muaj ntau yam tshuaj siv los kho tus mob narcolepsy thiab nws cov tsos mob muaj feem ntau yuav cuam tshuam nrog lwm yam tshuaj. Ntshav siab thiab lub plawv dhia tsis xwm yeem tsuas yog ob qho teeb meem uas tuaj yeem tshwm sim nrog txhua hom tshuaj txhawb zog. Sodium Oxybate, tshwj xeeb, yog qhov txaus ntshai heev thaum ua ke nrog lwm yam tshuaj uas ua rau lub paj hlwb hauv nruab nrab tsis ua haujlwm. Tsis tas li ntawd, tsis txhob siv cov tshuaj no nrog cawv .

Feem ntau, koj tus kws kho mob yog tus neeg zoo tshaj plaws los qhia rau koj paub txog cov kev mob tshwm sim, teeb meem, thiab kev sib cuam tshuam ntawm cov tshuaj uas koj yuav tsum paub. Nws tuaj yeem muab cov ntaub ntawv uas haum rau koj tus mob, keeb kwm kev noj qab haus huv, thiab koj tus kheej.

Kuv yuav ua li cas thiaj saib xyuas kuv tus kheej thiab tswj tau kuv cov tsos mob?

Koj yuav tsum tsis txhob sim kuaj mob lossis kho tus mob narcolepsy koj tus kheej . Qhov no yog vim tias cov tsos mob ntawm tus mob no kuj tshwm sim rau lwm yam mob hnyav, xws li pw tsaug zog apnea thiab qaug dab peg. Tsis tas li ntawd, tus mob no tuaj yeem ua rau qee yam kev ua ub no, xws li tsav tsheb thiab ua luam dej, txaus ntshai. Yog li ntawd, ib txwm mus ntsib kws kho mob kom kuaj mob thiab kho .

Kuv yuav zoo dua sai npaum li cas tom qab kho tas?

Lub sijhawm uas kev kho mob yuav pib ua haujlwm, lossis rau cov txiaj ntsig ntawm kev kho mob kom hnov, nyob ntawm ntau yam. Koj tus kws kho mob yog tus neeg zoo tshaj plaws los qhia koj tias yuav xav li cas raws li koj tus mob, nws yuav siv sijhawm ntev npaum li cas rau cov tshuaj kom ua haujlwm, thiab nws yuav siv sijhawm ntev npaum li cas kom pom kev hloov pauv hauv koj cov tsos mob.

Puas yuav txo tau lossis tiv thaiv tau qhov kev loj hlob ntawm tus mob narcolepsy?

Feem ntau, tus mob narcolepsy tshwm sim tsis tau xav txog. Yog li ntawd, nws tsis tuaj yeem txo qhov kev pheej hmoo ntawm kev tshwm sim lossis tiv thaiv nws kom tsis txhob tshwm sim.

Yog tias kuv muaj Narcolepsy, kuv yuav tsum xav li cas?

Kab mob Narcolepsy feem ntau tsis txaus ntshai. Tab sis kev pw tsaug zog sai sai thiab tsis tuaj yeem tswj tau tuaj yeem ua rau muaj kev cuam tshuam loj rau lub neej. Cov neeg uas muaj tus mob no yuav tsis tuaj yeem tsav tsheb (ib ntus lossis mus tas li - nws nyob ntawm lawv cov tsos mob thiab mob).

Txawm hais tias narcolepsy feem ntau tsis txaus ntshai, hauv Hom 1 narcolepsy, muaj kev pheej hmoo ntxiv ntawm kev raug mob los ntawm kev ntog thaum lub sijhawm ntawm cataplexy. Narcolepsy kuj tseem tuaj yeem ua rau muaj xwm txheej txaus ntshai thaum tsav tsheb, siv cov cuab yeej hluav taws xob lossis cov tshuab hnyav, lossis ua luam dej.

Thaum cov menyuam yaus muaj tus kab mob narcolepsy

Cov menyuam yaus uas muaj tus kab mob narcolepsy feem ntau muaj teeb meem nrog cov teebmeem ntawm tus mob no. Kev tsaug zog thaum nruab hnub ua rau nws nyuaj rau tsom mus rau kev ua haujlwm hauv tsev kawm ntawv, tswj kev sib raug zoo hauv zej zog, thiab koom nrog hauv tsev kawm ntawv thiab cov haujlwm sab nraud.

Txawm li cas los xij, Narcolepsy yog ib qho mob nkeeg. Yog li ntawd, cov menyuam uas muaj Narcolepsy muaj cai tau txais kev tiv thaiv raws li txoj cai. Cov tsev kawm ntawv kuj raug cai yuav tsum tau ua kom yooj yim. Piv txwv li, hloov cov sijhawm kawm, teem sijhawm pw tsaug zog lossis so, thiab ua kom yooj yim dua rau cov menyuam noj lawv cov tshuaj hauv tsev kawm ntawv. Koj tus menyuam tus kws kho mob menyuam lossis lwm tus kws tshwj xeeb tuaj yeem pab koj nrhiav cov kev daws teeb meem uas yuav pab koj tus menyuam.

Rau cov neeg laus ua haujlwm (Narcolepsy)

Ib yam li cov menyuam yaus raug tiv thaiv los ntawm txoj cai hauv tsev kawm ntawv, cov neeg laus uas muaj tus kab mob narcolepsy kuj raug tiv thaiv los ntawm txoj cai. Kev ntxub ntxaug rau ib tus neeg raws li tus mob, suav nrog tus kab mob narcolepsy, raug txwv (piv txwv li, hauv Tebchaws Meskas, raws li Txoj Cai Lij Choj rau Cov Neeg Muaj Kev Tsis Taus).

Vim yog txoj cai lij choj ntawd, cov neeg uas muaj tus kab mob narcolepsy tuaj yeem nrog lawv cov tswv ntiav tham ntawm lawv qhov chaw ua haujlwm thiab tau txais kev pabcuam kom lawv thiaj li ua haujlwm tau ntxiv thaum tswj hwm lawv tus mob.

Kuv yuav tsum saib xyuas kuv tus kheej li cas? (Cov lus qhia ua tau)

Yog koj muaj tus mob narcolepsy, muaj ntau yam uas koj ua tau los tswj koj tus mob thiab kom tau txiaj ntsig ntau tshaj plaws ntawm koj txoj kev kho mob. Ntau yam ntawm cov no suav nrog kev tswj tus cwj pwm pw tsaug zog zoo (Kev Huv Si Zoo) thiab hloov koj lub sijhawm thiab kev ua neej niaj hnub.

• Ua kom muaj kev pw tsaug zog tas li : Kev muaj tus cwj pwm mus pw thiab sawv tib lub sijhawm tuaj yeem txhim kho qhov zoo ntawm koj txoj kev pw tsaug zog.
• Teem sijhawm pw tsaug zog : Teem sijhawm pw tsaug zog uas koj yuav tau pw tsaug zog raws li koj lub hnub nyoog. Tsis tas li ntawd, teem sijhawm so thiab ua kom koj lub siab tus ua ntej mus pw.
• Txwv tsis pub raug lub teeb ci ntsa iab thiab cov khoom siv hluav taws xob : Lub teeb los ntawm cov khoom siv no ze rau lub sijhawm pw tsaug zog tuaj yeem cuam tshuam koj lub cev lub voj voog pw tsaug zog thiab sawv.
• Tsis txhob haus cawv, haus caffeine, haus luam yeeb, thiab noj mov ze rau lub sijhawm yuav mus pw.Yog tias koj tshaib plab ua ntej mus pw, noj mov me me xwb ces zoo tshaj. Yog tias koj noj qee yam tshuaj, koj yuav tsum tsum tsis txhob haus cawv kiag li (koj tus kws kho mob yuav qhia rau koj yog tias koj tau noj cov tshuaj no). Cov kws tshaj lij kuj pom zoo kom tsum tsis txhob haus luam yeeb kiag li (xws li luam yeeb, luam yeeb hluav taws xob (vaping)), thiab luam yeeb tsis muaj pa luam yeeb ((smokeless tobacco))).
• Ua kom lub cev nquag : Txawm tias nws tsuas yog ib yam dab tsi zoo li kev taug kev xwb, kev ua kom lub cev nquag tuaj yeem pab koj pw tsaug zog zoo.
• Pw tsaug zog : Cov neeg uas muaj tus kab mob narcolepsy feem ntau zoo siab dua tom qab pw tsaug zog. Nws tuaj yeem pab txiav txim siab seb lub sijhawm twg ntawm ib hnub koj xav tias koj tsaug zog tshaj plaws thiab teem sijhawm pw tsaug zog rau lub sijhawm ntawd.

Tsis txhob ua tej yam txaus ntshai, lossis ua tib zoo ceev faj.

Kev qaug zog ntawm lub hlwb (narcolepsy) tuaj yeem ua rau muaj xwm txheej loj heev, txawm tias tuag taus. Yuav kom tiv thaiv koj tus kheej thiab cov neeg nyob ib puag ncig koj, tsis txhob tsav tsheb tshwj tsis yog tias tus kws kho mob tau pom zoo .

Yog tias koj muaj cov tsos mob ntawm tus mob narcolepsy thaum tsav tsheb, tsum tsis txhob tsav tsheb tam sim ntawd thiab hu rau koj tus kws kho mob. Txawm hais tias qhov no yuav tsis xis nyob li cas los xij, nws yog ib qho tseem ceeb kom tiv thaiv kom tsis txhob muaj xwm txheej tuag taus lossis hloov pauv lub neej vim yog tsaug zog ntawm lub log.

Lwm qhov chaw uas tus kab mob narcolepsy tuaj yeem ua rau muaj kev phom sij tshwj xeeb yog nyob hauv dej . Yog tias koj muaj tus kab mob narcolepsy, nws yog ib qho tseem ceeb heev uas yuav tsum hnav lub tsho cawm siav kom raug thaum koj ua luam dej lossis nyob rau ntawm ib lub nkoj lossis lub nkoj caij dej uas pom zoo kom siv lub tsho cawm siav. Yog tsis muaj lub tsho cawm siav, kev pw tsaug zog hauv dej tuaj yeem ua rau muaj kev phom sij txog kev tuag taus.

Kuv yuav tsum mus ntsib kws kho mob thaum twg?

Yog tias koj tsaug zog tam sim ntawd, tsis tau xav txog, nws yog ib qho cim qhia tias koj yuav tsum mus ntsib kws kho mob. Qhov no tsis yog tsuas yog narcolepsy xwb, tab sis nws kuj tseem tuaj yeem qhia txog ntau yam mob. Qee qhov ntawm lawv yog qhov hnyav. Hauv ntau qhov xwm txheej, qhov ntev koj ncua kev kuaj mob thiab kev kho mob, qhov kev pheej hmoo ntawm cov teeb meem ntau dua lossis kev kho mob tsis zoo.

Kuv yuav tsum mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU) thaum twg?

Yog tias koj poob siab lossis tsis nco qab, nrhiav kev kho mob tam sim ntawd ntawm tsev kho mob lossis chav kho mob ceev. Qhov no yog ib qho tsos mob tseem ceeb ntawm ntau yam mob, suav nrog mob plawv nres, mob hlwb, thiab lub plawv dhia tsis xwm yeem. Cov mob no yog xwm txheej ceev thiab xav tau kev kho mob tam sim ntawd.

Kev raug mob ntsig txog kev poob yog kev raug mob uas tshwm sim thaum koj poob tsis tau xav txog, xws li los ntawm kev raug rub lossis tsis nco qab.Muaj kev pheej hmoo ntawm kev raug mob. Ib txwm nrhiav kev pab tswv yim los ntawm kws kho mob yog tias koj xav tias koj tau raug mob rau koj lub taub hau, caj dab, lossis ib feem ntawm koj nraub qaum. Cov pob txha tawg thiab raug mob rau cov hlab ntsha caj dab tuaj yeem ua rau puas tsuaj mus tas li, tuag tes tuag taw, thiab txawm tias tuag taus.

Yog koj ntog, thiab koj noj tshuaj uas ua rau cov ntshav nyias , tshwj xeeb tshaj yog tias koj tsoo koj lub taub hau, koj yuav tsum nrhiav kev kho mob tam sim ntawd. Kev ntog thiab raug mob tuaj yeem ua rau muaj kev ntshav sab hauv uas txaus ntshai. Koj xav tau kev kho mob kom paub tseeb tias koj tsis muaj kev raug mob uas yuav ua rau muaj teeb meem loj rau lub neej.

Cov lus tseem ceeb tshaj plaws uas koj yuav tsum nco ntsoov (Cov Lus Coj Mus Tsev)

Yog li, kuv vam tias koj tau nco qab qee yam tseem ceeb tshaj plaws los ntawm qhov peb tau tham txog (Narcolepsy).

• Kab mob Narcolepsy tsis yog tsuas yog kev tsaug zog los ntawm kev qaug zog xwb. Nws yog ib qho teeb meem nrog lub hlwb lub peev xwm los tswj kev pw tsaug zog thiab kev sawv.
• Yuav tsum paub txog cov tsos mob tseem ceeb ntawm kev tsaug zog ntau dhau thaum nruab hnub, cataplexy (cov leeg nqaij tsis muaj zog tam sim ntawd), pom kev tsis meej pem los ntawm kev pw tsaug zog, thiab pw tsaug zog tuag tes tuag taw . Tsis yog txhua tus neeg muaj cov tsos mob no.
• Qhov ua rau muaj tus mob no feem ntau yog kev txo qis ntawm cov tshuaj orexin hauv lub hlwb, lossis cov teeb meem autoimmune.
• Mob Narcolepsy yuav tsum tau kuaj mob tshwj xeeb kom paub tseeb tias mob. Yog li ntawd, tsis txhob maj txiav txim siab rau koj tus kheej.
• Txawm hais tias qhov no tsis tuaj yeem kho tau tag nrho, nws yog ib qho mob uas feem ntau tuaj yeem tswj tau los ntawm kev siv tshuaj thiab kev hloov pauv hauv lub neej .
• Xav txog kev nyab xeeb kom zoo. Ceev faj tshwj xeeb thaum tsav tsheb, ua luam dej, thiab ua haujlwm saum roob. Ua raws li cov lus qhia ntawm kws kho mob.
• Yog koj muaj cov tsos mob no, tsis txhob ntshai mus ntsib kws kho mob. Koj tsis yog tib leeg xwb. Kev pab muaj.

Vam tias cov ntaub ntawv no yuav pab tau koj. Yog tias koj lossis ib tus neeg koj paub tab tom ntsib teeb meem zoo li no, nws yog qhov zoo tshaj plaws los nrhiav kev pab kho mob sai li sai tau.

Narcolepsy , tsaug zog ntau dhau thaum nruab hnub, cataplexy, pw tsaug zog apnea, kev pom kev pw tsaug zog, orexin, kab mob hlwb