Cia peb kawm txog lub tswv yim zais cia uas tswj cov calcium hauv koj lub cev: Parathyroid Hormone (PTH).

Peb txhua tus muaj cov tshuaj me me uas ua haujlwm hauv peb lub cev, tsis pom, kom peb noj qab nyob zoo. Ib qho ntawm cov tshuaj no yog cov tshuaj parathyroid. Hais yooj yim xwb, cov tshuaj no tswj cov calcium hauv peb cov ntshav. Vim li cas nws thiaj tseem ceeb ua luaj? Vim tias calcium yog qhov tseem ceeb rau peb cov hlab ntsha, cov leeg, thiab lub plawv kom ua haujlwm tau zoo.

Cov tshuaj hormone parathyroid no (Parathyroid Hormone - PTH) yog tsim los ntawm peb cov qog parathyroid. Cov no nyob hauv peb lub caj dab, tom qab lub qog thyroid. Lawv yog plaub lub qog me me heev. Lawv txoj haujlwm tseem ceeb yog tswj cov calcium hauv peb cov ntshav . Nco ntsoov, nws tsis yog calcium hauv cov pob txha, tab sis calcium hauv cov ntshav. Tsis tas li ntawd, PTH no kuj pab tswj cov phosphorus thiab cov tshuaj hormone vitamin D hauv cov ntshav thiab cov pob txha.

Cov tshuaj parathyroid hormone (PTH) ua haujlwm li cas?

Zoo, tam sim no cia peb saib seb cov tshuaj parathyroid hormone (PTH) no ua haujlwm li cas. Thaum koj cov calcium hauv koj cov ntshav poob qis, cov qog parathyroid yuav tso PTH tawm. Nws zoo li lub sensor. PTH no ces mus thiab cuam tshuam rau ntau qhov ntawm peb lub cev kom coj cov calcium rov qab los.

• Pob Txha: Ua ntej, peb cov pob txha tau txais ib lub cim me me, hais tias, 'Tso qee cov calcium rau hauv cov ntshav.' Tom qab ntawd ntxiv me ntsis calcium los ntawm cov pob txha rau hauv cov ntshav. Qhov no tsis ua rau cov pob txha qaug zog, vim qhov no yog ib qho txheej txheem tswj hwm.
• Raum: Qhov thib ob, nws cuam tshuam rau peb lub raum. Ib qho yog tias lub raum pab tsim cov vitamin D uas nquag siv, uas hu ua calcitriol. Cov calcitriol no pab lub cev nqus cov calcium los ntawm cov khoom noj uas peb noj. Qhov thib ob yog tias nws qhia rau lub raum kom 'khaws cov calcium hauv lub cev, tsis txhob tso nws tawm hauv cov zis'. Ces cov calcium yuav tsis raug pov tseg.
• Plab hnyuv me: Qhov thib peb, raws li tau hais ua ntej, vitamin D (Calcitriol) xa ib lub cim rau peb txoj hnyuv me kom nqus tau ntau calcium los ntawm cov khoom noj uas peb noj.

Yog li ntawd PTH ua haujlwm kom tswj tau cov calcium hauv cov ntshav kom zoo los ntawm kev cuam tshuam rau ntau qhov ntawm lub cev. Qhov no puas yog ib qho txheej txheem zoo kawg nkaus?

Peb lub cev tswj cov PTH li cas?

Peb lub cev tswj tau qib PTH no li cas? Nws kuj tshwm sim rau hauv ib txoj kev txawv txawv heev. Nws hu ua lub voj voog rov qab . Hais yooj yim, thaum cov calcium hauv cov ntshav txo qis, cov qog parathyroid raug txhawb thiab tso tawm PTH. Thaum cov calcium hauv cov ntshav nce ntxiv, nws qhia rau cov qog kom 'tsis txhob ua PTH tam sim no, txaus'. Yog li ntawd yog li cas nws raug tswj. Nws zoo li lub cev muaj zog hauv tsev uas tig thaum cov dej hauv lub tank dej tsawg thiab tua thaum lub tank puv.

Txawm li cas los xij, qee zaum yog tias muaj teeb meem nrog peb cov qog parathyroid, qhov kev tawm tswv yim no yuav tsis ua haujlwm zoo, ua rau PTH ntau dhau lossis tsawg dhau los tsim tawm. Thaum ntawd cov teeb meem pib.

Yog tias cov theem PTH raug cuam tshuam, yuav muaj kab mob dab tsi tshwm sim?

Tam sim no cia peb saib seb cov mob dab tsi tuaj yeem tshwm sim yog tias cov tshuaj parathyroid hormone (PTH) raug cuam tshuam.

Yuav ua li cas yog tias PTH theem nce siab? (Hyperparathyroidism)

Yog tias cov PTH siab dhau, peb hu nws ua hyperparathyroidism . Tom qab ntawd muaj ob yam tseem ceeb tshwm sim:

• Cov calcium hauv cov ntshav nce ntxiv . Qhov no hu ua hypercalcemia.
• Cov phosphorus hauv cov ntshav txo qis . Qhov no hu ua hypophosphatemia.

Xav txog seb, PTH pheej tso cov calcium tawm ntawm cov pob txha mus rau hauv cov ntshav, tiv thaiv lub raum kom tsis txhob tso calcium tawm, thiab nqus ntau ntxiv los ntawm cov khoom noj ... thiab tom qab ntawd cov ntshav puv nrog calcium, puas yog? Qhov no zoo li lub yeeb nkab txhaws thiab dej ntws dhau.

Muaj ntau yam ua rau tus mob no, xws li:

• Parathyroid Adenoma: Qhov no tsis yog mob qog noj ntshav, tab sis qhov mob qog no ua rau lub qog tsim cov PTH ntau dhau. Qhov no yog qhov ua rau feem ntau tshwm sim.
• Parathyroid Hyperplasia: Tag nrho plaub lub qog ua rau loj hlob thiab tsim cov tshuaj hormones ntau dua.
• Kab Mob Raum: Qhov mob no tuaj yeem tshwm sim tshwj xeeb tshaj yog rau cov neeg uas muaj kab mob raum ntev. Vim tias thaum lub raum tsis ua haujlwm zoo, kev tsim cov vitamin D txo qis thiab kev tso tawm phosphorus txo qis. Qhov no ua rau cov qog parathyroid tsim cov PTH ntau dua.
• Mob Cancer Parathyroid: Qhov no tsis tshua muaj, tab sis nws tuaj yeem tshwm sim.

Yuav ua li cas yog tias cov PTH theem txo qis? (Hypoparathyroidism)

Yog tias cov PTH qis, nws hu ua hypoparathyroidism . Tom qab ntawd qhov txawv tshwm sim:

• Cov calcium hauv cov ntshav qis . Qhov no hu ua hypocalcemia.
• Cov phosphorus hauv cov ntshav nce ntxiv . Qhov no hu ua hyperphosphatemia.

Hypoparathyroidism yog ib qho mob tsis tshua muaj. Feem ntau ntawm cov mob (kwv yees li 75%) yog tshwm sim los ntawm kev puas tsuaj lossis tshem tawm cov qog parathyroid thaum lub sijhawm phais caj dab, tshwj xeeb tshaj yog phais thyroid. Nws kuj tseem tuaj yeem tshwm sim los ntawm qee yam mob caj ces thiab cov mob autoimmune - cov kab mob uas lub cev tiv thaiv kab mob tawm tsam nws cov hlwb.

Koj yuav paub li cas yog tias koj cov PTH tsis zoo li qub? Cov tsos mob yog dab tsi?

Zoo li peb tau tham ua ntej lawm, PTH feem ntau tswj cov calcium hauv cov ntshav. Yog li cov tsos mob uas tshwm sim thaum PTH qis lossis siab yog cov tsos mob ntawm cov calcium qis lossis siab hauv cov ntshav. Cia peb saib seb lawv yog dab tsi.

Cov tsos mob ntawm cov calcium hauv cov ntshav qis (Hypocalcemia):

Tej zaum koj yuav xav tias tej yam zoo li no:

• Lub hlwb tsis meej pem lossis tsis meej pem. Nws tuaj yeem zoo li koj lub taub hau puv nkaus hauv pos huab.
• Daim tawv nqaij qhuav, cov rau tes tawg yooj yim, thiab cov plaub hau poob tawm.
• Cov leeg nqaij mob, tshwj xeeb tshaj yog nyob rau hauv ob txhais ceg thiab caj npab.
• Mob tingling hauv koj daim di ncauj, ntiv tes lossis taw.
• Tej yam xws li kev ntxhov siab thiab kev nyuaj siab kuj tseem yuav tshwm sim.
• Thaum mob hnyav, tej zaum yuav muaj qaug dab peg.

Xav txog seb, Niluka cia li xav tias nws cov ntiv tes tsis muaj zog, khaus ncig nws lub qhov ncauj, thiab cov nqaij ntawm nws ob txhais ceg pib liab. Nws xav tias tsis xis nyob heev. Tsuas yog thaum nws mus ntsib kws kho mob nws thiaj li paub tias nws cov calcium hauv cov ntshav tau txo qis, thiab qhov ua rau yog hypoparathyroidism.

Cov tsos mob ntawm cov calcium hauv cov ntshav siab (Hypercalcemia):

Cov tsos mob zoo li no yuav qhia tau tias muaj calcium ntau hauv cov ntshav:

• Kuv xav tias kuv nkees heev, zoo li kuv tsis muaj zog (Qaug zog). Txawm kuv pw tsaug zog npaum li cas los xij, qhov qaug zog zoo li tsis ploj mus.
• Mob taub hau.
• Mob pob qij txha thiab mob pob txha.
• Yuav tsum tau tso zis ntau zaus thiab nqhis dej.
• Tej yam xws li mob plab, xeev siab, ntuav, thiab raws plab.
• Nyuaj rau kev tsom ntsoov, kev nco tsis zoo, thiab kev xav tsis meej.
• Hauv cov mob hnyav, yuav muaj pob zeb hauv lub raum thiab lub plawv dhia tsis xwm yeem tshwm sim.

Piv txwv li, Txiv ntxawm Saman tau nkees heev tau ob peb hnub lawm, thiab nws cov pob qij txha mob heev. Nws ib txwm nqhis dej thiab yuav tsum mus chav dej. Thaum kws kho mob kuaj nws, lawv hais rau nws tias nws cov calcium hauv cov ntshav siab me ntsis. Nws muaj mob hyperparathyroidism.

Yog koj muaj cov tsos mob no, uas txhais tau tias koj xav tias koj cov calcium hauv cov ntshav qis lossis siab, koj yuav tsum mus ntsib kws kho mob . Tsis txhob hnov ​​qab qhov ntawd. Cov no tsis yog cov tsos mob zoo uas yuav tsum tsis quav ntsej.

Yuav ua li cas los xyuas seb PTH qib li cas?

Koj tus kws kho mob tuaj yeem kuaj xyuas koj cov tshuaj parathyroid hormone nrog kev kuaj ntshav yooj yim . Cov kws kho mob thiab cov chaw kuaj mob hu qhov kev kuaj no tias "PTH, intact." Lawv kuj feem ntau kuaj xyuas koj cov calcium, phosphorus, thiab vitamin D hauv cov ntshav kom tau daim duab tiav.

Cov nqi ib txwm rau PTH yog dab tsi?

Hauv kev kuaj ntshav PTH ib txwm muaj, qib noj qab haus huv yog nyob nruab nrab ntawm 15 thiab 65 picograms ib milliliter (pg/mL) . Ib picogram yog ib trillionth ntawm ib gram. Qhov ntawd txhais tau tias muaj me me heev ua txoj haujlwm tseem ceeb no hauv peb lub cev.

Tiam sis muaj ib qho uas yuav tsum nco ntsoov yog tias cov nqi ib txwm no yuav txawv me ntsis ntawm ib lub chaw kuaj mob mus rau lwm lub chaw kuaj mob. Yog li ntawd, koj yuav tsum saib qhov ntau thiab tsawg ib txwm rau lub chaw kuaj mob ntawd ntawm koj daim ntawv qhia txog kev kuaj ntshav.

Yog koj muaj kev kuaj PTH, koj tus kws kho mob yuav yog tus uas yuav txhais cov txiaj ntsig kom raug. Nws/nws yuav piv rau koj cov calcium thiab qhia rau koj seb puas xav tau kev kuaj ntxiv.

Yog li ntawd, peb yuav tsum nco ntsoov dab tsi ntawm txhua yam no?

Cov Tshuaj Parathyroid Hormone (PTH) yog ib yam tshuaj tseem ceeb heev uas tswj cov calcium hauv peb cov ntshav kom zoo. Cov calcium no yog qhov tseem ceeb rau kev ua haujlwm zoo ntawm peb lub paj hlwb, cov leeg, thiab lub plawv.

Yog tias koj muaj cov tsos mob ntawm hypercalcemia (calcium ntau hauv cov ntshav) lossis hypocalcemia (calcium tsawg hauv cov ntshav), xws li teeb meem ntawm cov leeg nqaij, kev hloov pauv ntawm kev ua haujlwm ntawm lub hlwb, qaug zog ntau dhau, thiab mob pob txha, nws yog ib qho tseem ceeb uas yuav tsum nrhiav kev pab kho mob sai li sai tau. Yog tias cov mob no tseem muaj, lawv tuaj yeem ua rau lub raum, lub plawv, thiab pob txha puas tsuaj.

Koj tus kws kho mob tuaj yeem ua ob peb qhov kev kuaj yooj yim los txiav txim siab seb koj cov tshuaj parathyroid hormone puas yog qhov ua rau. Yog tias yog, lawv tuaj yeem pib kho tam sim ntawd. Qee zaum cov teeb meem no tuaj yeem kho tau nrog tshuaj, qee zaum nrog kev phais me me. Yog li, kev saib xyuas koj lub cev, nkag siab txog cov cim qhia uas nws muab, thiab ua raws li lawv yog txoj hauv kev zoo tshaj plaws los noj qab haus huv.

Cov tshuaj hormones parathyroid, PTH, calcium, hyperparathyroidism, hypoparathyroidism, hypercalcemia, hypocalcemia