Koj puas tau raug kev txom nyem los ntawm kev mob pob qij txha lossis mob plab hnyuv ntev lawm? Koj puas tau pom cov tsos mob tshiab xws li ceg o lossis zis ua npuas? Qhov no yuav yog ib qho mob tshiab cuam tshuam nrog koj qhov mob qub. Hnub no peb tab tom tham txog ib qho mob tsis tshua muaj tab sis tseem ceeb uas yuav tsum paub txog. Nws yog AA Amyloidosis.
AA Amyloidosis yog dab tsi?
Hais yooj yim xwb, qhov no yog ib yam kab mob tsis tshua muaj uas cuam tshuam rau cov protein hauv peb lub cev. Nws yog ib hom kab mob amyloidosis, uas yog ib pawg kab mob loj heev.
Xav txog cov protein hauv peb lub cev zoo li cov khaub ncaws uas muab tais zoo nkauj. Lawv muaj ib lub duab tshwj xeeb thiab ib lub luag haujlwm tshwj xeeb. Tab sis hauv tus kab mob no, cov qauv 3D ntawm qee cov protein raug cuam tshuam, thiab lawv dhau los ua tangled thiab tangled zoo li cov pob ntawm xov. Nws zoo li ib daim khaub ncaws uas tau raug crumpled rau hauv ib qho mess thiab pov tseg. Cov protein clumps disordered, uas peb hu ua amyloid deposits , pib sib sau ua ke hauv peb cov kabmob, tshwj xeeb tshaj yog nyob rau hauv qhov chaw xws li lub raum thiab siab.
Qhov no kuj hu ua 'secondary amyloidosis'. Qhov laj thawj rau qhov no yog tias nws tsis yog ib yam kab mob uas tshwm sim ntawm nws tus kheej. Nws tshwm sim ua ib qho kev phiv loj heev lossis teeb meem ntawm lwm yam kab mob o ntev hauv lub cev. Thaum muaj kev o hauv peb lub cev ntev, qib ntawm cov protein hu ua 'serum A protein' nce ntxiv hauv cov ntshav. Qib siab no yog qhov ua rau AA amyloidosis.
Tus mob no cuam tshuam li cas rau kuv lub cev?
AA amyloidosis tuaj yeem ua rau ntau yam kab mob tseem ceeb hauv koj lub cev puas tsuaj.
- Raum: Lub raum yog qhov feem ntau thiab feem ntau puas tsuaj los ntawm tus kab mob no.
- Siab
- Mob qog
- Plab thiab hnyuv
- Lub plawv: Lub plawv tsis tshua raug cuam tshuam.
Ntxiv rau qhov ua rau cov kab mob no puas tsuaj, qhov mob no kuj tseem tuaj yeem ua rau muaj protein ntau ntxiv hauv koj cov zis thiab kev hloov pauv ntawm cov roj cholesterol hauv cov ntshav.
Kab mob no tuaj yeem ua rau tuag taus yog tias tsis kho. Qhov zoo tshaj plaws yog tias thaum kho tus kab mob uas ua rau nws, tus mob AA amyloidosis kuj tseem tuaj yeem tswj tau.
Dab tsi ua rau muaj AA amyloidosis?
Raws li peb tau tham ua ntej lawm, qhov laj thawj tseem ceeb rau qhov no yog kev o ntawm lub cev mus ntev. Vim yog qhov o no, peb lub siab tsim ntau yam protein tshwj xeeb hu ua 'serum A protein'. Feem ntau, cov protein no raug siv tag thiab raug tshem tawm. Txawm li cas los xij, thaum muaj kev o tas mus li, cov protein no yuav tsim ntau dhau, hloov lawv cov duab, thiab, raws li tau hais ua ntej lawm, pib sib sau ua ke thiab tso rau hauv cov kabmob.
Muaj ntau yam mob uas ua rau mob o mus sij hawm ntev li no.
| Pawg kab mob | Piv txwv |
|---|---|
| Cov Kab Mob Ntev | Cov kab mob bacterial ntev xws li cov qhov txhab uas tsis kho tau ntev, mob ntsws. |
| Cov Kab Mob Rheumatic | Mob pob qij txha caj qaum, mob ankylosing spondylitis. |
| Cov Kab Mob Plab Hnyuv | Kab mob Crohn, mob plab hnyuv. |
| Qee hom mob qog noj ntshav | Qee hom mob qog noj ntshav. |
| Cov Mob Uas Tau Txais Los Ntawm Qoob Loo | Cov mob uas los ntawm noob caj ces uas ua rau muaj mob kub taub hau qee zaum, xws li Familial Mediterranean Fever. |
Cov tsos mob ntawm tus kab mob no yog dab tsi?
Cov tsos mob ntawm tus kab mob no feem ntau nyob ntawm seb lub raum puas raug mob. Vim tias feem ntau lub raum raug mob, cov tsos mob uas cuam tshuam nrog rau qhov ntawd feem ntau yog cov tsos mob uas tshwm sim.
| Cov tsos mob | Ib qho lus piav qhia yooj yim |
|---|---|
| O ntawm ob txhais ceg lossis pob luj taws | Cov hauv qab no tuaj yeem tshwm sim vim muaj cov kua dej sib sau ua ke hauv lub cev vim yog kev ua haujlwm ntawm lub raum tsis zoo. |
| Plab zom mov los yog ua npuas ncauj | Cov zis yuav ua npuas zoo li dej xab npum thaum lub raum tso cov protein tawm. Qhov no yog ib qho tsos mob tseem ceeb heev . |
| Cov zis tawm tsawg dua li qub | Nws tuaj yeem yog ib qho tsos mob ntawm tus kab mob raum ntev. |
| raws plab ntev | Cov amyloid deposits hauv cov hnyuv tuaj yeem cuam tshuam rau kev nqus zaub mov. |
| Lub siab lossis lub raum loj | Qhov no tuaj yeem kuaj pom thaum lub sijhawm kuaj mob. |
| Ntshav siab qis | Tej zaum yuav kiv taub hau, tshwj xeeb tshaj yog thaum sawv ntsug. |
| Xeev siab thiab ntuav | Qhov no tuaj yeem tshwm sim thaum lub cev zom zaub mov raug cuam tshuam. |
Tus kws kho mob nrhiav tau qhov no li cas?
Yog koj tus kws kho mob xav tias muaj tus kab mob no los ntawm koj cov tsos mob, txoj hauv kev tseem ceeb los paub tseeb tias yog kuaj mob. Qhov no txhais tau tias yuav tsum muab ib daim nqaij me me thiab kuaj nws hauv lub tshuab microscope.
Kev kuaj mob plab rog hauv plab
Qhov no yog ib qho kev kuaj yooj yim heev. Yuav muab ib daim rog me me ntawm daim tawv nqaij hauv qab koj lub plab coj mus kuaj. Feem ntau, qhov kev kuaj no tuaj yeem kuaj pom tus kab mob.
Kev kuaj lub cev
Qee zaum, nws yog ib qho tsim nyog yuav tsum tau muab ib daim nqaij me me ntawm lub cev uas xav tias puas lawm (piv txwv li, lub raum) thiab kuaj nws.
Nrog rau cov kev kuaj no, cov kws kho mob kuj kuaj xyuas lwm hom amyloidosis, xws li AL amyloidosis, uas muaj cov tsos mob zoo sib xws tab sis hnyav dua me ntsis.
Cov kev kho mob rau qhov no yog dab tsi?
Qhov tseem ceeb tshaj plaws hauv qhov no yog kho tus kab mob uas ua rau muaj AA amyloidosis, es tsis txhob kho nws ncaj qha.
Xav txog tias koj muaj mob rheumatoid arthritis. Tom qab ntawd cov kws kho mob yuav sau tshuaj los tswj koj tus mob rheumatoid arthritis kom zoo tshaj plaws. Tom qab ntawd qhov o ntawm lub cev yuav txo qis. Thaum qhov o txo qis, qhov kev tsim cov 'serum A protein' uas ua rau muaj teeb meem ntawd kuj yuav txo qis. Tom qab ntawd cov amyloid tshiab yuav nres, thiab cov tsos mob yuav maj mam pib txo qis.
Qhov ntawd txhais tau tias kev kho tus kab mob tseem ceeb yog txoj kev kho mob tseem ceeb rau AA amyloidosis.
Tsis tas li ntawd xwb, kev tshawb fawb tseem tab tom ua rau cov tshuaj tshiab uas tuaj yeem tshem tawm cov amyloid deposits uas twb tau tsim lawm.
Kab mob no puas kho tau tag nrho?
Yog, tus kab mob no yeej tswj tau thiab thim rov qab tau. Tiam sis nws nyob ntawm seb tus kab mob o uas ua rau nws puas raug tswj tau zoo npaum li cas.
Qhov tseem ceeb tshaj plaws yog kuaj mob sai li sai tau thiab pib kho qhov ua rau mob. Qhov no yuav pab tswj kev puas tsuaj rau cov kabmob thiab tiv thaiv kev puas tsuaj ntxiv.
Kuv yuav saib xyuas kuv tus kheej li cas?
Yog koj muaj AA amyloidosis, qhov zoo tshaj plaws uas koj ua tau yog nrog koj tus kws kho mob kho qhov mob tseem ceeb.
- Nug koj tus kws kho mob kom zoo zoo kom paub seb koj tus mob thawj zaug cuam tshuam li cas rau qhov no, kev kho mob twg tau muab rau nws, thiab yuav ua li cas ua raws li kev kho mob ntawd.
- Ntxiv rau koj tus mob qubYog koj muaj cov tsos mob tshiab (xws li ob txhais ceg o, zis ua npuas), tsis txhob tsis quav ntsej lawv zoo li lawv yog ib yam me me. Qhia rau koj tus kws kho mob txog lawv tam sim ntawd.
Kab mob AA amyloidosis yog ib qho teeb meem uas tsis tshua muaj tab sis loj heev ntawm ib yam kab mob uas ib txwm muaj. Zoo hmoo, nws tuaj yeem tswj tau los ntawm kev kho tus kab mob tseem ceeb. Yog li, ceev faj txog txhua yam kev hloov pauv hauv koj lub cev. Tham nrog koj tus kws kho mob txog txhua yam tsos mob tshiab. Nws yuav muaj peev xwm muab cov lus qhia uas koj xav tau rau koj.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- AA Amyloidosis tsis yog ib yam kab mob uas tshwm sim nws tus kheej. Nws yog ib qho teeb meem ntawm lwm yam kab mob uas mob ntev, xws li mob pob qij txha rheumatoid.
- Qhov no yog tshwm sim los ntawm cov protein hauv lub cev sib sau ua ke tsis sib xws thiab tso rau hauv cov kabmob xws li lub raum.
- Yog koj muaj mob ntev, tsis txhob tso tseg cov tsos mob xws li ob txhais ceg o thiab cov zis ua npuas ntau dhau.
- Txoj kev kho mob tseem ceeb rau qhov no yog tswj tus kab mob uas ua rau muaj qhov no .
- Kev kuaj pom thaum ntxov thiab kev kho mob txuas ntxiv mus rau qhov mob tseem ceeb tuaj yeem ua rau muaj txiaj ntsig zoo heev. Tham nrog koj tus kws kho mob txog cov tsos mob tshiab.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus