Thaum peb xav txog mob hawb pob, feem ntau ntawm peb xav txog lub tshuaj nqus pa. Qhov tseeb, rau ntau tus neeg, lub tshuaj nqus pa yog ib qho kev pab zoo hauv kev tswj lawv tus mob hawb pob. Tab sis qee zaum, tshwj xeeb tshaj yog rau cov neeg uas muaj mob hawb pob hnyav dua me ntsis, muaj qee zaum uas nws nyuaj rau siv lub tshuaj nqus pa kom raug. Kev ua pa nyuaj thiab nkees. Yog li hnub no peb yuav tham txog txoj kev kho mob tshiab, siab heev uas tau qhia los tswj cov mob hawb pob hnyav no. Nws hu ua Biologic Therapy.
Hais yooj yim xwb, Biologic Therapy yog dab tsi?
Qhov no yog ib txoj kev kho mob tshiab rau mob hawb pob hnyav. Lub tshuaj nqus pa uas peb feem ntau siv yuav ua rau cov leeg nqaij nyob ib puag ncig txoj hlab pa so, ua rau nws yooj yim dua rau kev ua pa. Tab sis kev kho mob biologic no txawv me ntsis.
Xav txog tias muaj tej yam me me hauv peb lub cev uas ua rau mob hawb pob, uas yog, o ntawm txoj hlab pa. Cov no hu ua cov tshuaj tua kab mob, cov hlwb, lossis cov molecule . Kev kho mob biologic tsom mus rau thiab thaiv cov haujlwm ntawm cov khoom uas ua rau mob hawb pob. Nws zoo li nrhiav qhov hauv paus ntawm qhov teeb meem thiab daws nws.
Kev kho mob no txo qhov zaus ntawm kev mob hawb pob rov tshwm sim, txhim kho qhov zoo ntawm lub neej, thiab rau qee tus neeg, tej zaum yuav txhim kho kev ua haujlwm ntawm lub ntsws mus rau qee qhov.
Cov tshuaj no muab rau lub cev li cas?
Kev kho mob biologic tsis tuaj yeem noj ua tshuaj ntsiav. Nws muab tau ob txoj hauv kev tseem ceeb:
1. Ua ib qho kev txhaj tshuaj: Qhov no yog ib qho kev txhaj tshuaj hauv qab daim tawv nqaij. Hauv cov lus kho mob, nws hu ua kev txhaj tshuaj hauv qab daim tawv nqaij .
2. Los ntawm kev muab tshuaj rau hauv cov hlab ntsha: Ib yam li kev muab tshuaj saline, cov tshuaj raug muab rau hauv lub cev los ntawm lub cannula. Qhov no hu ua kev txhaj tshuaj rau hauv cov hlab ntsha (IV) .
Qhov tseem ceeb yog tias kev kho mob siv tshuaj tsis yog kev kho mob uas sawv ntawm koj ib leeg xwb. Nws yuav tsum siv ua ke nrog lwm cov tshuaj kho mob hawb pob uas koj twb noj lawm.
Qhov no txhais tau tias koj yuav tsum tau noj cov tshuaj uas koj tus kws kho mob tau sau tseg, xws li:
- Cov tshuaj kho mob ua xua: Cov no suav nrog corticosteroids , antihistamines , thiab cov tshuaj antileukotriene (xws li montelukast ).
- Cov tshuaj txhaj tiv thaiv kev ua xua: Kuj hu ua kev kho mob tiv thaiv kab mob , cov no tuaj yeem txo cov tsos mob ntawm kev ua xua raws sijhawm.
- Tshuaj nqus pa rau mob hawb pob: Txhua yam tshuaj nqus pa uas tau muab los tswj koj tus mob hawb pob hnyav yuav tsum tau txuas ntxiv nrog kev kho mob no.
Txoj kev kho mob no puas haum rau leej twg tiag?
Kev kho mob biologic tsis yog muab rau txhua tus neeg mob hawb pob. Koj tus kws kho mob yuav xav txog ntau yam ua ntej pom zoo kom siv txoj kev kho mob no rau koj. Saib seb koj puas tau ntsib ib qho ntawm cov no.
- Yog tias koj cov tsos mob tsis raug tswj txawm tias koj siv koj cov tshuaj kho mob hawb pob uas tau sau tseg, tshwj xeeb yog koj lub tshuaj nqus pa, kom raug .
- Yog tias koj muaj cov qib siab ntawm qee yam hauv koj cov ntshav , tshwj xeeb tshaj yog eosinophils ( ib hom qe ntshav dawb uas ua rau o hauv lub ntsws) lossis cov allergens ntau (immunoglobulin E lossis IgE) .
- Yog koj paub tias dab tsi ua rau koj mob hawb pob thiab sim zam lawv, tab sis koj cov tsos mob tseem muaj .
- Yog koj sawv thaum ib tag hmo vim ua pa nyuaj .
- Yog tias koj yuav tsum siv koj lub tshuaj nqus pa cawm siav ntau tshaj ob zaug hauv ib lub lim tiam.
- Yog tias koj yuav tsum siv cov tshuaj xws li corticosteroids los txo qhov o ntawm txoj hlab pa ntau dua ob zaug hauv ib xyoos thaum koj tus mob hawb pob zuj zus tuaj.
- Yog tias koj yuav tsum mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU) ntau tshaj ob zaug hauv ib xyoos vim muaj cov tsos mob ntawm tus mob hawb pob.
- Yog koj tau nyob hauv tsev kho mob thiab tau txais kev kho mob vim yog mob hawb pob.
Yog tias koj muaj ib qho mob zoo li no, nws yog ib qho tseem ceeb heev uas yuav tsum nrog koj tus kws kho mob tham txog seb kev kho mob biologic puas yog rau koj.
Cov tshuaj siv rau mob hawb pob yog hom twg?
Muaj ntau hom tshuaj biologic uas tau txais kev pom zoo los ntawm cov koom haum xws li U.S. Food and Drug Administration (FDA). Txhua tus ntawm lawv ua haujlwm sib txawv me ntsis. Cia peb saib seb lawv yog dab tsi.
| Lub npe tshuaj (lub npe hom tshuaj) | Nws ua haujlwm li cas thiab nws haum rau leej twg? | Yuav muab li cas | Cov kev mob tshwm sim feem ntau |
|---|---|---|---|
| Omalizumab (Xolair®) | Kho mob hawb pob uas ua rau muaj kev ua xua. Thaiv cov tshuaj tiv thaiv kab mob uas ua rau muaj kev ua xua. Haum rau cov neeg uas ua xua rau cov kab me me, tsiaj txhu, kab laum, pwm, thiab lwm yam. | Txhaj tshuaj 1 lossis 2 zaug txhua 2 txog 4 lub lim tiam. Thaum xub thawj muab rau hauv kev saib xyuas ntawm kws kho mob, tom qab ntawd qee tus tuaj yeem tau txais lawv hauv tsev. | Mob nqaij, mob pob qij txha, qaug zog, mob lossis o ntawm qhov chaw txhaj tshuaj. |
| Mepolizumab (Nucala®) | Kho mob hawb pob uas muaj cov kab mob eosinophilic. Thaiv ib yam khoom hu ua IL5 uas ua haujlwm rau cov eosinophils hauv cov ntshav. | Txhaj tshuaj ib zaug txhua 4 lub lim tiam. Noj tau hauv tsev. | Mob taub hau, mob los yog o ntawm qhov chaw txhaj tshuaj, mob nraub qaum, tsis muaj zog, qaug zog. |
| Reslizumab (Cinqair®) | Qhov no kuj kho tau tus mob hawb pob uas muaj eosinophilic. Ib yam li mepolizumab, nws thaiv (IL5). | Muab ua ib txoj kev txhaj tshuaj IV txhua 4 lub lis piam. Nws siv sijhawm tsawg dua ib teev. Yuav tsum tau muaj kev saib xyuas los ntawm kws kho mob thaum xub thawj. | Mob caj pas, mob nqaij. |
| Benralizumab (Fasenra®) | Kho cov mob hawb pob uas muaj eosinophilic. Txo cov eosinophils hauv cov ntshav. | Cov koob tshuaj thawj zaug yog muab txhua 4 lub lis piam, tom qab ntawd txhua 8 lub lis piam. | Mob taub hau, mob caj pas. |
| Dupilumab (Dupixent®) | Kho cov mob hawb pob uas muaj cov kab mob eosinophilic. Thaiv lwm yam tshuaj uas ua rau mob hauv lub cev. | Ib koob tshuaj txhua 2 lub lis piam. | Mob caj pas, mob lossis o ntawm qhov chaw txhaj tshuaj, cov qe ntshav dawb ntau ntxiv. |
| Tezepelumab (Tezspire®) | Ib yam tshuaj tshiab rau kev kho mob hawb pob. Nws kho mob hawb pob hnyav los ntawm kev txo qhov o. | Ib koob tshuaj txhua 4 lub lis piam. | Mob caj pas, mob nraub qaum, mob pob qij txha. |
Lwm cov lus nug uas koj muaj txog kev kho mob no
Nws yog ib qho ib txwm muaj ntau lo lus nug tshwm sim hauv koj lub siab thaum tham txog kev kho mob tshiab zoo li no. Cia peb saib cov lus teb.
Kev kho mob yuav siv sijhawm ntev npaum li cas?
Txog tam sim no, tseem tsis tau muaj lus qhia meej tias yuav tsum siv tshuaj no ntev npaum li cas. Tej zaum yuav siv sijhawm tsawg kawg yog plaub lub hlis los txiav txim siab seb nws puas pab txo koj cov tsos mob ntawm tus mob hawb pob. Yog li ntawd, nws suav tias yog kev kho mob mus sij hawm ntev.
Cov tshuaj biologic zoo tshaj plaws yog dab tsi?
Tsis muaj peev xwm hais tias ib yam tshuaj zoo dua lwm yam. Tsis muaj kev tshawb fawb sib piv cov tshuaj no. Koj tus kws kho mob yuav txiav txim siab seb hom tshuaj twg zoo tshaj plaws rau koj. Nws yuav xav txog ntau yam, xws li koj qhov kev kuaj ua pa, kev kuaj ntshav, thiab hom mob hawb pob uas koj muaj.
Kuv puas yuav tsum tau siv lub tshuaj nqus pa ntxiv?
Yog! Muaj tseeb tiag. Qhov no tseem ceeb heev. Txawm tias tom qab pib kho mob biologic lawm los, tsis txhob tsum siv koj lub tshuaj nqus pa thiab lwm yam tshuaj kho mob hawb pob. Yog tias koj tus mob hawb pob tswj tau zoo, koj tus kws kho mob yuav muaj peev xwm txo koj cov tshuaj nqus pa raws sijhawm. Tab sis qhov kev txiav txim siab ntawd yog nyob ntawm koj.
Cov txiaj ntsig ntawm kev kho mob biologic yog dab tsi?
Qhov txiaj ntsig tseem ceeb ntawm kev kho mob no yog kom txo qhov o ntawm cov hlab pa thiab tswj cov tsos mob ntawm tus mob hawb pob. Tsis tas li ntawd xwb, tseem muaj ntau yam txiaj ntsig ntxiv:
- Koj yuav muaj peev xwm koom nrog kev ua ub ua no thiab kev tawm dag zog ib txwm muaj .
- Thaum tus mob hawb pob zuj zus tuaj, qhov zaus ntawm kev khiav mus rau ETU txo qis.
- Qhov xav tau lossis noj tshuaj kho mob ua xua yuav raug txo kom tsawg.
- Kuv tsaug zog zoo vim kuv tsis sawv thaum hmo ntuj vim kuv ua pa nyuaj.
- Tus naj npawb hnub uas koj tsis tuaj kawm ntawv lossis ua haujlwm vim muaj mob hawb pob yuav txo qis.
Puas muaj kev pheej hmoo nrog kev kho mob no?
Feem ntau, kev kho mob siv tshuaj lom neeg muaj kev nyab xeeb heev. Txawm li cas los xij, zoo li txhua yam tshuaj, muaj qee qhov kev pheej hmoo thiab cov kev mob tshwm sim.
- Kev ua xua hnyav heev: Tsis tshua muaj neeg yuav muaj kev ua xua hnyav rau cov tshuaj no. Nws tuaj yeem ua rau tawv nqaij ua pob, khaus, ua pob khaus, thiab qee zaum ua rau muaj mob hnyav hu ua anaphylaxis . Tab sis tsis txhob ntshai. Qhov no yog vim li cas cov kws kho mob yuav saib xyuas koj li ob teev tom qab muab cov tshuaj rau koj.
- Kev pheej hmoo ntawm kev kis tus kab mob parasitic ntau ntxiv: Cov tshuaj biologic, tshwj xeeb tshaj yog cov uas txo cov eosinophils hauv cov ntshav, yuav ua rau muaj kev pheej hmoo ntawm kev kis tus kab mob parasitic. Cov eosinophils no yog cov hlwb uas pab peb lub cev tiv thaiv kab mob tawm tsam cov kab mob parasitic, tshwj xeeb tshaj yog helminths .
- Mob hawb pob zuj zus yog tias kev kho mob raug tso tseg: Yog tias koj tso tseg kev kho mob biologic tam sim ntawd, muaj feem ntau uas koj cov tsos mob ntawm mob hawb pob yuav hnyav dua li yav dhau los.
Thaum twg koj yuav tsum tau nrog koj tus kws kho mob tham?
Nco ntsoov nrog koj tus kws kho mob tham hauv cov xwm txheej hauv qab no.
- Yog tias koj cov tsos mob ntawm tus mob hawb pob tsis zoo dua lossis zoo li hnyav zuj zus tom qab ob peb lub hlis ntawm kev kho mob.
- Yog tias muaj cov tsos mob tshiab ntawm kev ua xua (xws li tawv nqaij ua pob, khaus) pib tshwm sim.
- Yog koj tsis nco hnub ntawd ces koj yuav tsum tau noj koj cov tshuaj lossis yuav tsum tau hloov nws.
- Yog koj muaj lus nug lossis kev tsis ntseeg txog qhov kev kho mob no.
Kuv mus nrhiav kev kho mob no tau qhov twg? Puas muaj kev pov hwm them nqi?
Ib tug kws kho mob uas tshwj xeeb hauv kev kho mob hawb pob yuav txiav txim siab seb kev kho mob biologic puas yog rau koj. Nws yuav tshuaj xyuas koj cov tsos mob, cov tshuaj tam sim no, thiab cov txiaj ntsig ntawm kev kuaj ntshav. Kev kho mob no feem ntau yog muab rau hauv chaw ua haujlwm ntawm tus kws kho mob tshwj xeeb lossis hauv chav tshwj xeeb (chaw txhaj tshuaj) ntawm tsev kho mob.
Kev kho mob no yuav kim heev, yog li ntawd nrog koj tus kws kho mob tham seb koj daim ntawv pov hwm puas yuav them rau nws. Nws tuaj yeem pab koj kom paub tseeb los ntawm kev tham nrog koj lub tuam txhab pov hwm. Qee lub tuam txhab tshuaj kuj muaj cov kev pab nyiaj txiag rau cov neeg uas tau txais kev kho mob no.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Kev kho mob biologic yog kev kho mob siab heev rau kev mob hawb pob hnyav uas nyuaj rau tswj nrog cov tshuaj ib txwm muaj.
- Qhov no yeej tsis yog ib yam khoom siv los hloov koj lub tshuaj nqus pa. Koj yuav tsum txuas ntxiv siv koj lub tshuaj nqus pa.
- Tej zaum yuav siv sijhawm ntau lub hlis thiaj li pom cov txiaj ntsig ntawm kev kho mob, yog li ua siab ntev.
- Tsuas yog koj tus kws kho mob tshwj xeeb thiaj li txiav txim siab tau tias kev kho mob biologic twg zoo tshaj plaws rau koj.
- Ua ntej pib txoj kev kho mob no, nco ntsoov tham txog cov txiaj ntsig thiab tej yam txaus ntshai nrog koj tus kws kho mob.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus