Yu dɔn yɛri bɔt wan Gleason Score fɔ prɔstat kansa? Lɛ wi tɔk bɔt am!

We di dɔktɔ tɛl yu se yu gɛt prɔstat kansa, yu go mɔs fil bɔku strɛs ɛn wɔri, nɔto so? Da tɛm de, yu kin yɛri bɔt nyu mɛdikal tɛst ɛn kɔmplikɛt wɔd dɛn. Yu kin yɛri, ɔ yu kin dɔn yɛri, wan wɔd na di ‘Gleason Score’. So, wen yu yɛri dis, yu kin fred se, "Wetin na dis nyu tin?" Na dat mek, tide wi go tɔk bɔt wetin dis Gleason Score bi, ɛn wetin i rili se bɔt yu kɔndishɔn, insay wan simpul we we yu go ɔndastand.

Yu no wetin na Gleason Score?

Fɔ tɔk am simpul wan, if yu gɛt prɔstat kansa, di Gleason Score na we fɔ asɛs di kayn kansa – aw i tan lɛk, aw i kin spre fast, aw i kin agresiv, ɛn ɔda tin dɛn I tan lɛk fɔ gred tɛst na skul, bɔt i kin bi smɔl mɔ sayɛns ɛn i kɔmplikt.

Dis na sɔntin we patɔlɔjis ( spɛshal pipul dɛn we de chɛk di tisu ɛn no bɔt sik dɛn) kin du bay we dɛn de luk wan sɛmpul pan yu prɔstat tisu (smɔl pat we dɛn tek we dɛn de du bayɔpsi) ɔnda maykroskɔp fɔ no aw di kansa sɛl dɛn tan. Dis skɔring sistɛm de ɛp dɔktɔ dɛn fɔ plan di bɛst tritmɛnt fɔ yu ɛn mek prɛdikshɔn bɔt yu prɔgnosis afta tritmɛnt.

Aw dɛn kin kɔl di Gleason Score?

Okay, naw mek wi luk aw dɛn mek dis Gleason Score. As a bin dɔn tɔk, di wan dɛn we de mɛn sik dɛn kin du dis impɔtant wok. Dɛn kin luk di tisu sɛmpul dɛn frɔm yu prɔstat fayn fayn wan ɔnda maykroskɔp. If yu gɛt prɔstat kansa, dat min se sɔm pan di sɛl dɛn na yu prɔstat dɔn chenj frɔm nɔmal, wɛlbɔdi sɛl dɛn to kansa sɛl dɛn .

Imajin, we di fɔs tɛm, dɛn kansa sɛl ya kin tan lɛk sɛl dɛn we gɛt wɛlbɔdi. Jɔs disgiz. Bɔt as tɛm de go, as di kansa de go bifo, di we aw dɛn kansa sɛl ya de apia kin rili difrɛn ɛn nɔ kin fayn frɔm di sɛl dɛn we gɛt wɛlbɔdi. Dat difrɛns, da abnɔmal tin de, na wetin di wan dɛn we de stɔdi bɔt sik dɛn kin gred.

Sistɛm fɔ gredin

Dɛn kin gi ɛni tisu sampul wan mak frɔm 1 to 5 bay di kayn we aw di kansa sɛl dɛn tan, dat na aw dɛn difrɛn frɔm di sɛl dɛn we gɛt wɛlbɔdi. Dɛn kɔl dis di kansa gred .

• Gret 1: Di kansa sel dεm de luk bכku lεk hεlty, nכmal sεl dεm. Dat min se, na smɔl difrɛns nɔmɔ de. Dɛn arenj dɛn di rayt we.
• Gret 2-4: .i tan lεk se di kεnsar sεl dεm na di tisu difrεn sכmtεm frכm di hεlty sεl dεm εn i tan lεk se dεn nכ de rεgεl mכr. As di gred de go ɔp, dis difrɛns ɛn di tin we nɔ de apin ɔltɛm de sho mɔ.
• Gret 5: Di kansa sel dεm nכ de rili abnכmal, dεn de luk rili disכganayz εn dεn nכ de na di ples wit hεlty sεl dεm. Dis na di sɛl dɛn we de fɛt pas ɔl.

Naw, prɔstat kansa kin gɛt di sem sɛl dɛn na di sem eria, ɔ i kin gɛt difrɛn gred sɛl dɛn na difrɛn say dɛn. So, wetin di pathologist de du na fɔ pik di men eria usay di kansa dɔn spre mɔ ɛn gi am gred (bitwin 1-5). Dɔn, dɛn kin pik di sɛkɔn say we spred pas ɔl (we gɛt difrɛn patɛn) ɛn gi am gred. Dɔn dɛn kin ad di tu men gred dɛn togɛda. Dat som na yu Gleason Score.

Fɔ ɛgzampul, lɛ wi se di kansa we bɔku pas ɔl na gred 3. Di nɛks wan we bɔku pas ɔl na gred 4. Dɔn di Gleason skɔ go bi 3 + 4 = 7. Wan ɔda ɛgzampul, if di patɛn we de dominant na gred 4 ɛn di sɛkɔndari patɛn na gred 3, di Gleason skɔ go bi 4 + 3 = 7. So pan ɔl we 3+4 ɛn 4+3 na ɔl tu 7, sɔm tɛm dɔktɔ dɛn kin tink bɔt di כda fכ dεn patεn dεm ya (hכy gred fכs).

Jɛnɛral wan, if dis kɔmbayn Gleason skɔ na 6 ɔ pas dat, dɛn kin tek am as kansa.

Yu tink se sɔntin de we dɛn kɔl nɔmal Gleason Score?

Naw yu kin de wɔnda, "nɔmal" Gleason Score de? Fɔ tru, nɔtin nɔ de we dɛn kɔl "nɔmal" Gleason Score, lɛk we wi de chɛk wi blɔd shuga lɛvɛl fɔ dayabitis, ɔ we wi luk wi prɔstat kansa PSA lɛvɛl ɛn se, "Na di nɔmal rɛnj." Bifo dat, dɔktɔ dɛn kin sheb di Gleason Score to tri kategori ɛn yuz dɛn fɔ ɔndastand aw di kansa de biev:

• Gleason score 6: Insay dis kes, di kansa sεl dεm de luk rili lεk di hεlty sεl dεm. Wi kin kɔl dis ``wɛl difrɛns'' kansa. fכ simpul wan, di sεl dεm stil lεk "gud pikin dεm," we de tray fכ lεk nכmal sεl dεm. Dɛn kin tek dɛn wan ya as kansa we de gro sloslo, we nɔ kin gɛt bɛtɛ agresiv.
• Gleason score 7: Insay dis kes, di kansa sel dεm de luk sכmtεm lεk hεlty sεl dεm, bכt sכm tin dεm de we nכ de rεgulεr. Wi kin kɔl dis ``moderately differentiated'' kansa. Dis na lɛk di midul grɔn. Smɔl difrɛns kin de bitwin 3+4=7 ɛn 4+3=7. di 4+3 patεn sכmtεm dεn kin kכnsidr am sכmtεm as kכndishכn we de kכnsεn sכmtεm pas di 3+4 patεn.
• Gleason skɔ 8, 9 ɔ 10:Insay dis kes, di kansa sɛl dɛn rili difrɛn frɔm di sɛl dɛn we gɛt wɛlbɔdi. Dɛn nɔ kin rili difrɛn, i kin lɛf smɔl fɔ lɛ dɛn nɔ difrɛn. Wi kin kɔl dis ‘poorly differentiated’ ɔ ‘undifferentiated’ kansa. Dɛn sɛl ya kin agresiv smɔl, ɛn i tan lɛk se dɛn gɛt ay chans fɔ gro ɛn skata kwik kwik wan.

Wetin na gud Gleason Score fɔ prɔstat kansa?

I at fɔ lɛbul wan Gleason skɔ wantɛm wantɛm se "gud" ɔ "bad." Bɔt fɔ no yu Gleason skɔ kin gi yu dɔktɔ wan impɔtant aidia bɔt aw yu prɔstat kansa de gro kwik ɛn aw i go izi fɔ mek i go na ɔda pat dɛn na di bɔdi. Di Gleason skɔ de frɔm 6 to 10.

Jɛnɛral wan, if di Gleason skɔ smɔl (fɔ ɛgzampul, 6), dɛn kin tek am as ‘lɔ-grɛd kansa.’ Dɛn kayn kansa ya kin gro sloslo ɛn nɔ kin go ɔda say dɛn.

If di Gleason skɔ ay (fɔ ɛgzampul, 8, 9, 10), dɛn kin tek am se na ‘hay-grɛd kansa.’ Dɛn kayn kansa ya kin gro ɛn prɛd kwik kwik wan.

Bɔt, i impɔtant fɔ mɛmba dis: Yu Gleason skɔ na jɔs wan infɔmeshɔn we dɔktɔ dɛn kin yuz fɔ plan yu tritmɛnt ɛn gi yu prɔgnosis. Dat min se Gleason skor nɔmɔ nɔto di ansa. Na jɔs wan pat pan wan big pikchɔ.

Na di Gleason Score nɔmɔ impɔtant?

Nɔ, nɔto so atɔl. As a bin se bifo, yu Gleason Score na jɔs wan pat pan di pazl. Dɔktɔ dɛn kin tek bɔku ɔda tin dɛn na kɔna fɔ ɔndastand yu kɔmplit sik ɛn pik di bɛst tritmɛnt fɔ yu.

Fɔ ɛgzampul, we yu bin de du yu bayɔpsi, yu dɔktɔ go dɔn tek sɔm sɛmpul dɛn, we dɛn kɔl kɔr, frɔm yu prɔstat. So,

• Ɔmɔs pan dɛn kɔr dɛn (pies dɛn na di tisu) bin gɛt kansa sɛl dɛn?
• Us pasɛnt pan ɛni `(kɔr)` bin ful-ɔp wit kansa sɛl?

A de luk bak pan tin dɛn lɛk dat.

Apat frɔm dat, dɛn tin ya rili impɔtant bak:

• Yu blɔd `(PSA)` lɛvɛl. (PSA - Prostate-Specific Antigen) (wan spɛshal blɔd tɛst).
• di rizulεt fכ di dijital rεktal εgzam (DRE) we di dכkta du (dat na di we aw dεn de fil di gland na di an).
• Infɔmeshɔn frɔm spɛshal imej tɛst lɛk ɔltra saund skan, MRI skan, ɔ PET skan kin ɛp fɔ no aw di kansa saiz ɛn aw i de skata.
• If di kansa de na ɔl tu di say dɛn na di prɔstat gland.
• Dɛn se prɔstat kansa dɔn skata (metastasized) to ɔda pat dɛn na di bɔdi, fɔ ɛgzampul, di bon dɛn.
• Yu ej ɛn ɔl yu wɛlbɔdi.

Fɔ put ɔl dis togɛda, lɛk fɔ kɔmplit wan big pazl, na aw yu dɔktɔ go disayd wetin na di bɛst tritmɛnt fɔ yu, bay aw yu sik. So, no wori unnecessarily abaut di Gleason skoa, okay?

Di tin we impɔtant pas ɔl we yu nid fɔ mɛmba (Take-Home Message) .

Okay, so na di impɔtant tin fɔ mɛmba frɔm wetin wi dɔn tɔk bɔt. Di Gleason Score na impɔtant tul we de kategoriz prɔstat kansa ɛn gi yu aydia bɔt aw i agresiv. Yu dɔktɔ kin yuz am fɔ plan di bɛst tritmɛnt fɔ yu. di Gleason Score kin kכmכt frכm 6 (lכw grεd, lεs agresiv kεnsar) to 10 (high-grεd, mכr agresiv kεnsar). Kansa we gɛt smɔl Gleason Score kin gro sloslo ɛn dɛn nɔ kin gɛt bɛtɛ risk fɔ spre.

Bɔt dɛn nɔmba ya nɔmɔ nɔ de tɛl di wan ol stori bɔt yu prɔstat kansa. Dat stori kin bigin wit yu tritmɛnt plan ɛn ɔndastand wetin yu kin ɛkspɛkt frɔm dɛn tritmɛnt dɛn de, ɛn bak di gud ɛn bad tin dɛn. Yu Gleason skɔ ɛn ɔda tɛst rizɔlt tan lɛk gayd fɔ ɛp yu pan yu joyn fɔ wɛl.

If yu ɛva gɛt ɛni kwɛstyɔn ɔ wɔri bɔt yu Gleason Score, ɛni ɔda tɛst rizɔlt, ɔ yu mɛdikal kɔndishɔn, nɔ shek fɔ aks yu dɔktɔ. I go gladi fɔ ɛksplen wetin dɛn nɔmba ɛn wɔd dɛn de min ɛn ansa ɛni kwɛstyɔn we yu gɛt. Mɛmba se nɔto yu wan de pan dis waka. Dɔktɔ ɛn wɛlbɔdi tim de de fɔ ɛp yu ɛn kia fɔ yu.

` Prɔstat kansa, Gleason skɔ, kansa sɛl, tisu tɛst, kansa stej, man dɛn wɛlbɔdi, kansa tritmɛnt