Lɛ wi no bɔt yu CEA tɛst (Carcinoembryonic Antigen)? As dɔktɔ, a go tɛl yu dis simpul wan!

Yu go dɔn yɛri bɔt di CEA tɛst, ɔ yu dɔktɔ dɔn tɛl yu fɔ du am. So, wetin na di CEA tɛst? Wetin mek dɛn kin du am? A no se yu gɛt bɔku kwɛstyɔn dɛn lɛk dis na yu maynd. Nɔ wɔri, tide wi go tɔk bɔt di CEA tɛst insay wan simpul we we yu go ɔndastand. A no se we yu yɛri tin dɛn lɛk dis, yu kin fred smɔl, bɔt wans yu no di ditil dɛn, da fred de go dɔn.

Wetin na CEA (Carcinoembryonic Antigen)? Lɛ wi ɔndastand am simpul wan!

Imajin, wi gɛt wan spɛshal kayn prɔtin na wi bɔdi. Dis na wetin wi kɔl CEA, ɔ Carcinoembryonic Antigen . dis na rili protin (glycoprotein) we gεt bכku shuga we de atak am. dis kin bi bay nכmal sεl dεm εn sכm kεnsar sεl dεm.

Na wan rili strenj tru tin se we wi ɔl bɔn, wi gɛt rili ay lɛvɛl fɔ dis CEA na wi bɔdi. As wi de ol, dat min se as wi de ol, dis CEA lεvεl de dכn sכmtεm. Bɔt pan sɔm sik dɛn, mɔ we sɔm kayn kansa de kam, di lɛvɛl we CEA de na wi blɔd kin go ɔp bak.

Sayɛnsman dɛn bin fɔs fɛn CEA insay 1968, we dɛn bin chɛk sɔm pat dɛn pan kɔlorektal kansa we bin dɔn go na di liva ɛn sɔm pat dɛn na di dijestiv trakt fɔ di pikin we gɛt wɛlbɔdi.

Sɔntɛnde dɛn kin kɔl CEA bak tumor mak ɔ tumor antijen . Tumɔ mak na tin dɛn we sɔm kansa sɛl dɛn mek ɛn ad to wi bɔdi wata (lɛk blɔd ɛn urine). Bɔt mɛmba se sɛl dɛn we gɛt wɛlbɔdi kin mek dɛn tumbu mak ya bak, bɔt dɛn kin mek dɛn smɔl smɔl. Bɔrku pipul dɛm wae gɛt wɛl bɔdi kin gɛt dɛn tin ya na di "nɔmal rεnj." Yu lab ripɔt kin se dis as di "nɔmal rɛnj," "rɛfrɛns rɛnj," ɔ "rɛfrɛns intaval."

Us kayn kansa dɛn kin yuz di CEA tɛst mɔ fɔ?

Dis na di say we bɔku pipul dɛn kin mek mistek. Di CEA tɛst nɔ go ebul fɔ no fɔ tru if yu gɛt kansa ɔ yu nɔ gɛt kansa. Dat min se, nɔto fɔ chɛk fɔ no if yu gɛt kansa.

So wetin mek dɛn de du dis? Dɛn kin yuse am mɔ fɔ pipul dɛn we dɛn dɔn ɔlrɛdi no se gɛt kansa. Dis impɔtant mɔ fɔ pipul dɛn we gɛt kɔlorektal kansa.

Dɔktɔ dɛn kin yuz di CEA tɛst bak wit ɔda tɛst dɛn fɔ no, trit, ɛn wach difrɛn kansa dɛn. Fɔ ɛgzampul, dɛn kin yuz am fɔ no if pɔsin gɛt blad kansa, bɔdi kansa, lɔng kansa, ovarian kansa, ɛn tayroyd kansa.

Fɔ tɔk am simpul wan, dɛn kin yuz di CEA tɛst fɔ si aw pɔsin we sik de ansa to kansa tritmɛnt, fɔ si if di sik dɔn kam bak (relaps), ɔ fɔ no if di kansa dɔn kam bak (recurrence). Bɔt nɔto dis tɛst nɔmɔ dɛn kin yuz. Yu dɔktɔ kin yuz am fɔ ɛgzamin yu bɔdi ɛn if nid de, fɔ tɛst yu pikchɔ dɛn.

So, insay us sityueshɔn dɛn nid fɔ mek dɛn du CEA tɛst?

As a bin dɔn tɔk, dɛn nɔ de yuz di CEA tɛst fɔ no if pɔsin gɛt kansa. Bɔt if yu dɔn gɛt kansa, dis tɛst kin gi yu rili impɔtant infɔmeshɔn. Yu dɔktɔ kin yuz di CEA tɛst fɔ:

• Si if di kansa dɔn gro ɔ i dɔn skata to ɔda pat dɛn na di bɔdi (metastasized).
• Asɛs aw di tritmɛnt fɔ kansa kin wok fayn. Yu kin nid fɔ mek dɛn du dis tɛst pan dɛn tin ya:
• we dεn dכn no di sik, i de εp fכ mek wan tritmεnt plan (dεn kכl dis `baseline testing` ).
• We dɛn de trit kansa (e.g., si aw tritmɛnt dɛn lɛk kimotɛrapi, imyunotɛrapi, ɛn redyushɔn tɛrapi de wok fayn).
• Afta di tritmɛnt dɔn dɔn, chɛk fɔ si if di kansa dɔn kam bak (i ​​de kam bak).
• Afta dɛn dɔn no se yu gɛt kansa, bifo dɛn trit yu ɛn/ɔ ɔpreshɔn. Dɔn, we dɛn de trit am, dɛn kin du dis tɛst wan tɛm insay di mɔnt ɔ ɛvri tri mɔnt.
• Bɔt na wan impɔtant tin fɔ no: We di CEA lɛvɛl go ɔp insay 4-6 wik afta yu bigin fɔ trit am, dat nɔ kin min ɔltɛm se di tritmɛnt nɔ wok, di sik dɔn kam bak, ɔ di kansa dɔn kam bak. Yu dɔktɔ go tɛl yu mɔ bɔt dis.
• Wae di sik dɔn dɔn, yu kin nid fɔ kɔntinyu fɔ du CEA tɛst fɔ chɛk fɔ si if i kam bak. Yu dɔktɔ go disayd aw ɔltɛm dɛn fɔ du dis.

Aw yu kin du dis CEA tɛst?

Bɔku tɛm, dɛn kin du di CEA tɛst as blɔd tɛst . Yu dɔktɔ ɔ nɔs go tek smɔl blɔd frɔm wan vein we de na yu an. Dɔn, spɛshal pipul dɛn na di lab go chɛk da blɔd sɛmpul de ɛn chɛk di CEA lɛvɛl.

Bɔt nɔto ɔltɛm, yu dɔktɔ kin luk bak fɔ CEA lɛvɛl na ɔda bɔdi wata. Fɔ ɛgzampul:

• Pɛritonial fluid (fluid we dɛn tek frɔm di wɔl na di bɛlɛ) .
• Fluid we de na di pleura
• di wata we dεn tek frכm di spεnal kכd (dεn kכl dis ``sεribrospεnal fכluid כ CSF'') .

If na so i bi, yu dɔktɔ go yuz nidul ɔ sirinj fɔ tek smɔl smɔl wata. Dɛn kin put di nidul insay yu chɛst ɔ yu bak.

Aw a fɔ pripia fɔ di CEA tɛst?

Nid nɔ de fɔ rɛdi bɔku tin fɔ dis. Yu dɔktɔ go tɛl yu aw fɔ pripia. Dɛn kin aks yu fɔ stɔp fɔ tek sɔm mɛrɛsin dɛn we de mek yu blɔd bɔku (lɛk aspirin) fɔ sɔm dez. Yu dɔktɔ go ɛksplen ɔl dis to yu.

Wetin fɔ ɛkspɛkt we yu de tek di CEA tɛst?

If dɛn mɛzhɔ CEA insay blɔd:

• Dɔktɔ ɔ nɔs go put smɔl nidul insay wan vein na yu an (bɔku tɛm nia yu ɛlb).
• Dɛn kin kɔnɛkt wan smɔl bɔtul (vayl) ɔ tɛst tyub to am.
• Dɔn dɛn kin tek smɔl blɔd sɛmpul. Dis kin tek lɛk fayv minit so.

If dεn tek sεmpl frכm כda bכdi wata (e.g., spεnal fכluid):

• Fɔs, dɛn kin injekt wan lokal anestetik na yu bɔdi we de dɔŋ ɛn na yu chɛst fɔ mek i nɔ gɛt bɛtɛ trɛnk.
• Dɔn dɛn kin put nidul ɔ sirinj insay di rayt we.
• Sɔntɛnde, dɛn kin yuz ɛkstrem rayt fɔ chɛk if di nidul de na di rayt ples.
• afta dat, dεn tek wan sεmpl fכ εni wan pan di `(CSF),` `(pleural fluid),` כ `(peritoneal fluid)`.

Dis kayn tɛst kin tek lɛk 30 minit so. Yu kin go na os di sem de we dɛn de du di tɛst.

Ɛni risk de wit di CEA tɛst?

CEA test dεm jεnarali rili sef. כltu, na rili sכm risk de fכ dεn tin ya we dεn de tεst di pleura fluid:

• Sɔntɛm sɔm blɔd go de.
• Wan infekshɔn kin apin.
• Smɔl damej kin de na di lɔng dɛn.

Bɔt bɔku pipul dɛn nɔ kin gɛt ɛni kɔmplikeshɔn frɔm CEA tɛst. Yu dɔktɔ go ɛksplen dɛn bad bad tin ya to yu mɔ bifo di tɛst. So natin nɔ de fɔ wɔri bɔt.

Us sayd ɛfɛkt dɛn kin apin afta di CEA tɛst?

If yu bin du blɔd tɛst, yu kin gɛt sɔm smɔl brus ɔ swel usay dɛn put di nidul fɔ tu ɔ tri dez. Dis na nɔmal tin.

If dɛn tek wan sɛmpul pan yu sɛribrospaynal fluid (CSF) ɔ abdominal fluid, yu kin gɛt smɔl smɔl sayd ɛfɛkt dɛn lɛk:

• Diziz we pɔsin kin gɛt
• Ɛd we de at
• Layt ed we pɔsin kin gɛt

Bɔku tɛm, dɛn tin ya kin bɛtɛ insay sɔm dez.

Wetin di rizɔlt fɔ di CEA tɛst min?

Yu dɔktɔ kin yuz di rizɔlt fɔ di CEA tɛst fɔ no mɔ bɔt di kansa.

• If di CEA lɛvɛl smɔl, i kin min se di tɔŋ smɔl ɛn i nɔ dɔn spre to ɔda pat dɛn na di bɔdi. Bɔt sɔm kayn kansa (espɛshali di wan dɛn we de na ples lɛk di bren) nɔ kin mek bɔku CEA. If na so i bi, di valyu fɔ di CEA blɔd tɛst kin smɔl. If dɛn kayn tin ya apin, dɔktɔ dɛn kin tink bak bɔt fɔ du skan lɛk MRI.
• If di CEA lɛvɛl ay, i kin min se di kansa big ɔ i dɔn spre to ɔda pat dɛn na di bɔdi.Bɔt mɛmba se, di CEA lɛvɛl nɔmɔ nɔ go ebul fɔ tɛl yu ustɛm di kansa de (tumor stej) ɔ if i dɔn skata to ɔda pat dɛn na di bɔdi (metastasized).

Yu dɔktɔ kin wach yu CEA lɛvɛl ɔlsay na yu kansa tritmɛnt. If yu CEA lɛvɛl go dɔŋ bad bad wan we yu de trit yu, bɔku tɛm dis kin sho se di tritmɛnt de wok. Bɔt di dɔktɔ dɛn go kɔnfirm dis wit di ɛgzam fɔ di bɔdi ɛn skan.

Wetin na nɔmal CEA lɛvɛl?

di CEA lεvεl dεm dεn kin ripot insay nanogram pan wan mililita (ng/mL) . nכmal lεvεl de bitwin 0 εn 2.9 ng/mL.

dכkta dεm jεnarali kin kכnsidr CEA lεvεl bitwin 0 εn 2.9 ng/mL fכ nכmal. כltu, sכm risεch dεn sho se lεvεl dεm we hכy lεk 35 ng/mL kin mek fכs-positiv risכlt. Dis min se CEA kin ɛlevɛt ivin if yu nɔ gɛt kansa.

Dis nɔmal rɛnj (rɛfrɛns rɛnj) kin difrɛn smɔl bitwin di lab dɛm, ɛn dɔktɔ dɛn kin tink bɔt ay limit dipen pan di wan wan pɔsin in kɔndishɔn.

Wetin na di CEA lɛvɛl we de sho se pɔsin gɛt kansa?

Na dis na di impɔtant pɔynt. Nɔ patikyula CEA lɛvɛl nɔ de we go ebul fɔ tɔk kɔrɛkt wan if kansa de. As a bin dɔn tɔk, dɔktɔ dɛn nɔ kin yuz di CEA tɛst fɔ chɛk ɔ no if pɔsin gɛt kansa. jεnarali, CEA lεvεl we pas 2.9 `(ng/mL)` dεn kin kכnsidr am as abnכmal, bכt i nכ min כltεm se kεnsar de.

Yu tink se di CEA lɛvɛl kin go ɔp if yu nɔ gɛt kansa?

Yɛs, i rili ebul fɔ du am! If yu gɛt ay CEA lɛvɛl nɔ kin min ɔltɛm se kansa de. Fɔ ɛgzampul, pipul dɛm wae de smok kin gɛt ay CEA lɛvɛl.

di CEA lεvεl kin εlevεt bak biכs fכ di kכndishכn dεm we nכ de fכ kεnsar lεk:

• Gastritis ɛn bɛlɛ ɔlsa
• Kronik Obstrɔktiv Pulmonari Diziz (COPD) .
• Liva sik, fɔ ɛgzampul sirosis, liva we gɛt fat, ɔ gal ston
• Divεrtikulayt na inflameshn na di sכm sכm pכch dεm na di big intestin.
• Shuga
• Ɛni sik we pɔsin kin gɛt we i de fɛt insɛf ɔ we kin mek pɔsin in bɔdi wam
• Inflammatory bowel diseases (e.g. Krohn sik ɛn ɔlsa kɔlayt) .
• Ɛmɔroyd dɛn
• Nyumonia (inklud COVID-19 nyumonia) .

כlso, pipul dεm we de tek sכm tritmεnt dεm we dεn mek wit animal mεtirial (e.g., monoklonal antibodi dεm) kin gεt εlevεt CEA lεvεl dεm bak.

So, wetin na di las tin dɛn we wi fɔ mɛmba? (Mɛsej we dɛn kin tek go na os)

Okay, wi don tok plenti boht di CEA tehst naw. A op se yu ɔndastand am gud gud wan. Fɔ tɔk smɔl:

• CEA na spɛshal protin (glycoprotein) we de na wi bɔdi.
• Sɔm kayn kansa kin mek di CEA lɛvɛl go ɔp. Bɔt we di CEA lɛvɛl go ɔp nɔ kin min ɔltɛm se kansa de. Bɔrku rizin de fɔ mek CEA kin bɔku ivin if yu nɔ gɛt kansa.
• Di CEA tɛst nɔto tɛst fɔ no if pɔsin gɛt kansa.
• Dɛn kin yuse dis mɔr fɔ si aw pipul dɛm wae dɔn ɔlrɛdi gɛt kansa de ansa tritmɛnt ɛn fɔ fala di sik.
• If yu gɛt ɛni kwɛstyɔn bɔt yu CEA lɛvɛl ɔ di tɛst, tɔk to yu dɔktɔ. Dɛn go gi yu di bɛst advays.

Mɛmba se insay mɛrɛsin, wan tɛst nɔ kin ebul fɔ no ɔltin. CEA na jɔs wan pan dɛn kayn ɛp dɛn de. Yu dɔktɔ go disayd fɔ du di bɛst tin bay aw yu gɛt wɛlbɔdi. So, nɔ fred ɔ wɔri we yu nɔ nid. Tɔk to yu dɔktɔ bɔt ɛnitin ɛn sɔlv am.

` CEA test, carcinoembryonic antigen, kansa mak, blɔd tɛst, kansa tritmɛnt, kansa monitarin, tumor mak