Wi go tɔk bɔt DNA tɛst ɛn jenɛtik tɛst?

Yu go mɔs dɔn yɛri wɔd dɛn lɛk ‘DNA tɛst’ ɛn ‘jɛnɛtik tɛst’, nɔto so? Sɔntɛnde na fim, ɔ na nyus. Wetin na dɛn tin ya rili? Wetin mek dɛn dɔn du dɛn? Wetin wi kin lan frɔm dɛn? Lɛ wi tɔk bɔt ɔl dis ditayli, rili simpul wan, tide.

Wetin na Jɛnɛtik Tɛst?

Fɔ tɔk am simpul wan, tɛst fɔ yu jɛnɛtiks na tɛst we de luk fɔ chenj dɛn na yu jin , kromozom , ɔ prɔtin . Dɛn kin kɔl dis bak DNA tɛst . Dis tεst na fכ tek sεmpl fכ yu blכd, skin, ia, tisu, כ if yu de εkspεkt pikin, di amniotic fluid we de rawnd yu pikin. Dis tɛst kin kɔnfɔm ɔ ruul ɔut if yu gɛt jɛnɛtik kɔndishɔn. I kin ɛp yu bak fɔ no aw yu go gɛt wan sik we yu gɛt wit yu jɛnɛtiks tumara bambay, ɔ aw yu go pas wan sik we yu gɛt wit yu pikin to yu pikin.

Wetin di jenɛtik tɛst dɛn kin luk fɔ?

Okay, so wetin rili dɛn jenɛtik tɛst ya de luk fɔ? Dɛn kin luk mɔ fɔ chenj dɛn na yu jin, kromozom, ɛn prɔtin. Imajin, DNA tɛst kin tɛl yu bɔku tin bɔt yu bɔdi, aw yu luk, ɛn di jin dɛn we de mek yu bi pɔsin.

• Dis kin kɔnfirm if yu gɛt wan patikyula sik ɔ yu nɔ gɛt am.
• Dis kin tɛl yu bak if yu de pan big risk fɔ gɛt sɔm sik dɛn.
• Nɔto dat nɔmɔ, dɛn tɛst ya kin chɛk bak if yu gɛt wan jin we dɔn chenj we yu go ebul fɔ pas to yu pikin.

Us kayn DNA tɛst dɛn de?

Lɛ wi luk sɔm men kayn dɛn.

1. Fɔ tɛst di jin dɛn

Dis min se yu fɔ chɛk yu DNA ɛn luk fɔ chenj dɛn na yu jin dɛn, we dɛn kɔl mutations . Dɛn muteshon ya kin mek ɔr kin mek pɔrsin gɛt sɔm kayn sik wae de kam pan pɔrsin in jɛnɛtiks. Dɛn jenɛtik tɛst ya kin luk jɔs wan jin, sɔm jin, ɔ ɔl yu DNA. We yu luk yu ɔl DNA, dɛn kɔl am genomic testing .

2. Tɛst fɔ di kromozom dɛn

Kromozom tεst na tεst dεm we de luk yu kromozom dεm, we na lכng strεn dεm na DNA. Dɛn kin luk fɔ chenj dɛn na di ɔda we aw di jin dɛn de. Dɛn chenj ya kin mek pɔsin gɛt prɔblɛm wit in jɛnɛtiks. Fɔ ɛgzampul, dɛn kin no if yu gɛt ɛkstra kɔpi fɔ wan kromozom .

3. Fɔ Tɛst di Protɛin dɛn

di prכtin tεst dεm de analכz di kεmikכl dεm we de apin insay wi sεl dεm, lεk di εnzym aktiviti . If prɔblɛm de wit yu prɔtin dɛn, dat min se chenj kin de na yu DNA. Dɛn chenj dɛn de kin mek bak di tin dɛn we de apin na di jɛnɛtiks.

Jɛnɛtik tɛst dɛn we dɛn kin du difrɛn tɛm dɛn

Naw lɛ wi si us sityueshɔn dɛn jenɛtik tɛst ya kin yusful.

Tɛst we dɛn kin du bifo dɛn bɔn pikin

if yu bεlε, yu kin fכnכt if yu pikin we yu bכn gεt εni mכtεshכn na in jin כ kromozom we i bεlε, tru di DNA tεst dεm bifo i bכn. Bɔt mɛmba se dɛn tɛst ya nɔ kin no ɔltin we pɔsin gɛt. Bɔt dɛn kin tɛl yu aw yu go bɔn yu pikin wit sɔm pan di tin dɛn we wi no se wi kin no. Fɔ ɛgzampul, if sɔmbɔdi na yu famili gɛt jɛnɛtik histri , we min se yu pikin de pan ay risk fɔ gɛt wan jenɛtik kɔndishɔn, yu dɔktɔ kin tɛl yu fɔ du dɛn tɛst ya bifo i bɔn.

Diagnostik Tɛst we dɛn kin du

Dɛn tɛst ya fɔ no if yu gɛt patikyula sik dɛn we yu gɛt frɔm yu jɛnɛtiks ɔ yu gɛt prɔblɛm wit yu kromozom . Bɔt dɛn nɔ kin ebul fɔ tɛst ɔl di tin dɛn we de apin to dɛn jɛnɛtiks. Pan ɔl we dɛn kin yuz dɛn tɛst ya fɔ no if yu gɛt bɛlɛ, dɛn kin du dɛn ɛnitɛm fɔ kɔnfirm se yu dɔn no if yu gɛt sayn dɛn fɔ wan sik.

Tɛst fɔ di wan dɛn we de kɛr pipul dɛn

sכm sik dεm de we dεn kin pas dכn frכm jεnereshכn to jεnereshכn as ``Autosomal Recessive`` . Dat min se pɔrsin kin gɛt di jin fɔ da sik de, bɔt nɔr kin sho sɔm sayn dɛm. I jɔs de kɛr da jin de. dat min se yu kin fכnכt if yu na kכriכ fכ wan mutated jin fכ wan sכm ``Autosomal Recessive`` sik tru kכriכ tεst. dis kin bi if wan pan di mama εn papa gεt famili histri fכ wan ``Autosomal Recessive`` sik. Bikɔs, fɔ mek pikin gɛt dis kayn sik, di mama ɛn di papa ɔl tu nid fɔ gɛt kɔpi fɔ da jin de. So, if dɛn no se wan na pɔsin we gɛt di sik, if dɛn tɛst di ɔda wan bak, dɛn kin no aw di pikin dɛn go gɛt da sik de.

Tɛst we dɛn kin du bifo dɛn put am na di bɔdi

Dis na tɛst we spɛshal smɔl. dεn kin du am bay we dεn de yuz εsist riprodaktiv tεknik (ART) , fכ egzampl , in vitro fεtilayzεshכn (IVF).di tεst we dεn du bifo dεn implant dεm kin no di jεnεtik mכtεshכn dεm na di εmbrayo dεm we dεn de mek. dis involv fכ tek fכs sεl dεm frכm di εmbrayo dεm εn tεst dεm fכ spεshal mכtεshכn dεm. afta dat, na di εmbrayo dεm we nכ gεt dεn mכtεshכn dεm nכmכ dεn kin put insay di uterus fכ tray fכ bεlε.

Skrin fɔ Nyu Bɔn dɛn

Dɛn go chɛk yu pikin fɔ sɔm dez afta dɛn bɔn am. Dis nyu bɔbɔ we dɛn kin chɛk kin chɛk fɔ sɔm kayn tin dɛn we gɛt fɔ du wit di jɛnɛtik, mɛtabolik, ɔ ɔmon . Dɛn kin chɛk nyu bɔbɔ dɛn kwik kwik wan bikɔs if prɔblɛm de, dɛn kin bigin fɔ trit dɛn kwik kwik wan. Ɛni kɔntri/stet kin disayd us kɔndishɔn dɛn fɔ skan fɔ dis we. Fɔ ɛgzampul, ɔspitul dɛn na Amɛrika kin chɛk pikin dɛn we dɛn jɔs bɔn fɔ pas 35 sik dɛn.

Prɛdiktiv ɛn Prɛsimptomatik Tɛst

jin mכtεshכn dεm we de inkrεs yu risk fכ divεlכp wan jεnεtik kכndishכn insay di fכs tεm dεn kin fכnshכn tru prεdiktiv εn prε-symptomatic tεst. Dis kin tɛst fɔ si if di chenj dɛn we de apin na yu jin dɛn kin mek yu gɛt sɔm sik dɛn. Fɔ ɛgzampul, sɔm kayn kansa , lɛk bɔdi kansa, de insay dis kategori. Test bifo yu gɛt di sik kin tɛl yu if yu go gɛt wan jenɛtik kɔndishɔn bifo yu gɛt ɛni simptom. Bɔt i nɔ go ebul fɔ bi 100% shɔ. Smɔl chans de ɔltɛm fɔ mek mistek we dɛn de du dɛn kayn tɛst ya. So, tɔk to yu dɔktɔ bɔt dis bifo yu du ɛni tɛst.

Us sik dɛn kin no bay we dɛn de tɛst dɛn jɛnɛtiks?

Dis rili impɔtant. I impɔtant fɔ mɛmba se pan ɔl we dɛn kin tɛst sɔm tin dɛn we gɛt fɔ du wit dɛn jɛnɛtiks, dɛn nɔ kin ebul fɔ no ɔltin . Dɔn bak, if yu gɛt di tɛst rizɔlt, dat nɔ min se yu go gɛt di sik. Bɔt dɛn jenɛtik tɛst ya kin fayn fɔ kɔnfɔm ɔ pul bɔku difrɛn sik ɛn kɔndishɔn dɛn. Na sɔm ɛgzampul dɛn ya:

• `Dɔwn Sindrom` `(Dɔwn Sindrom)`
• Di Sik we Huntington bin gɛt
• Sistik Faybrosis we pɔsin kin gɛt
• `Sikl Sεl Sik` `(Sikl Sεl Sik)`
• `Fɛnilkɛtonuria` `(Fɛnilkɛtonuria)`
• Kɔlɔn (Kɔlɔrektal) Kansa
• Brɔst Kansa

Bɔku ɔda sik dɛn de we tan lɛk dis.

Aw dɛn kin du dɛn DNA tɛst ya?

I rili simpul. Yu dɔktɔ go tek wan sampul frɔm yu. I kin bi yu blɔd, yu ia, smɔl pat pan yu skin, tisu, ɔ if yu gɛt bɛlɛ , di wata we de rawnd yu pikin.I kin bi se na so i bi. dis amniotic fluid na di wata we de rawnd yu pikin we yu bεlε. Dɔn di dɔktɔ go sɛn dis sampul to wan lɛbɔtri. Na di lɛbɔretri, di wan dɛn we sabi du di wok go chɛk fɔ si if ɛnitin dɔn chenj na yu jin, kromozom, ɔ prɔtin. Fɔ dɔn, di tɛknishian dɛn go sɛn di tɛst rizɔlt to yu dɔktɔ.

Wetin na di bad tin dɛn we kin apin we dɛn de tɛst pɔsin in jɛnɛtiks?

Di fyzikal risk dɛm fɔ bɔku pan di jenɛtik tɛst dɛm rili smɔl. Bɔt we dɛn de du tɛst bifo dɛn bɔn pikin, i nɔ kin izi fɔ mek dɛn gɛt bɛlɛ . dis na biכs di tεst involv fכ tek sεmpl fכ di amniotic fluid we de rawnd yu pikin na yu bεlε.

Bɔt we dɛn de tɛst pɔsin in jɛnɛtiks, dat kin mek i gɛt mɔ prɔblɛm dɛn , pan pɔsin in maynd ɛn pan mɔni biznɛs.

Imajin, if yu gɛt sɔntin we yu nɔ bin de tink se go apin, yu go vɛks, fred, fil bad, wɔri , ɔ yu go fil gilti . Apat frɔm dat, fɔ tɛst pɔsin in jɛnɛtiks kin tek bɔku mɔni, ɛn sɔntɛnde i kin tek bɔku bɔku mɔni. Inshɔrans kin kɔba dis kɔst. Bɔt bɔku tɛm i kin dipen pan di kayn tɛst ɛn di rizin we mek dɛn du di tɛst.

pan tap dat, di jεnεtik tεst dεm nכ de gi infכmeshכn bכt כl di jεnεtik kכndishכn dεm, εn nכto כl di tεst dεm na 100% akכrd. Dɛn nɔ kin ebul fɔ tɔk bak bɔt aw di sik go tranga ɔr ustɛm wan sik we dɛn kin gɛt frɔm dɛn jɛnɛtiks go kam.

Wetin di tin dɛn we kin apin we dɛn du DNA tɛst kin se?

Nɔto ɔltɛm i kin izi fɔ ɔndastand di tin dɛn we kin apin we dɛn du DNA tɛst. Yu dɔktɔ go yuz di kayn tɛst, yu mɛdikal istri, ɛn yu famili istri fɔ ɛksplen di rizɔlt. Dɔn, i go ɛksplen to yu di patikyula tin dɛn we go apin. Dɛn kin sheb di rizɔlt dɛn lɛk dis:

• Pozitiv: If yu DNA tɛst rizɔlt na pɔsitiv, dat min se di lab dɔn ebul fɔ fɛn wan jenɛtik muteshɔn we dɛn no se kin mek pɔsin gɛt sik. Dis kin kɔnfirm se yu gɛt di sik, no se yu gɛt di sik, ɔr no se yu gɛt mɔ risk fɔ gɛt di sik.
• Negatif: If yu DNA test rizulyt negatif, dat min se di lab nɔ bin ebul fɔ fɛn wan jenɛtik mutation we dɛn no na yu DNA we kin mek yu gɛt sik. Dis kin mek yu nɔr no se yu gɛt dis sik, no se yu nɔr gɛt dis sik, ɔr no se yu nɔr de pan big risk fɔ gɛt dis sik.
• Nɔ shɔ se:If yu DNA tɛst rizɔlt nɔ klia, dat min se di lab kin dɔn fɛn wan jɛnɛtik muteshɔn. Bɔt dɛn nɔ gɛt bɛtɛ infɔmeshɔn fɔ no if na nɔmal tin ɔ na muteshon we de mek pɔsin sik. dis na biכs כlman gεt nכmal, nכmal vεryushכn dεm na in DNA we nכ de afekt in hεlth.

Aw di DNA tɛst dɛn kin kɔrɛkt?

Tu we dɛn de fɔ no if di tɛst dɛn we dɛn kin du fɔ tɛst pɔsin in jɛnɛtiks kɔrɛkt. Wan na di analitik validiti. dis de luk if DNA tεst kin kכrekt fכ no if mכtεshכn na wan spεsifi k jin de כ nכ de. Di ɔda wan na klinik validiti. Dis min if, if muteshon de, i gɛt fɔ du wit wan patikyula sik ɔ kɔndishɔn. Ɔl di laboratori dɛm we de du DNA tɛst, dɛn de rigul dɛn akɔdin to di standad dɛm we gɔvmɛnt dɔn gri wit. Dɛn mek dɛn standad ya fɔ mek shɔ se di tɛst dɛn we dɛn de du fɔ di jenɛtiks kɔrɛkt.

Aw lɔng i kin tek fɔ gɛt di rizɔlt fɔ DNA tɛst?

Sɔm tɛst rizɔlt dɛn kin gɛt insay sɔm dez. di tεst dεm we dεn kin du bifo dεn bכn, spεshal wan, kin kam bak kwik kwik wan. Bɔt ɔda tɛst dɛn kin tek sɔm wiks fɔ gɛt rizɔlt. Yu dɔktɔ go gi yu patikyula infɔmeshɔn bɔt ustɛm yu go gɛt yu rizɔlt fɔ di tɛst we yu de du.

Wetin na di bɛst DNA tɛst kit?

Infakt, if yu want fɔ du DNA tɛst, di bɛst tin fɔ du na fɔ mit wit dɔktɔ ɔ pɔsin we de advays yu bɔt yu jɛnɛtiks we de nia yu ɛn mek dɛn du di tɛst. Dɔn dɛn go ɛp yu fɔ pik di rayt tɛst fɔ yu ɛn tɔk to yu bɔt wetin di rizɔlt min we yu gɛt dɛn. Bɔt if yu nɔ ebul fɔ go tru dɔktɔ, yu kin gɛt DNA tɛst kit bak dairekt frɔm wan kɔmni we de tɛst DNA. dis dεn kכl am ``Direct-to-Consumer'' (DTC) jεnεtik tεst. Di bɛst DNA tɛst kit dɛn de gi infɔmeshɔn we izi fɔ ɔndastand bɔt di sayɛns we dɛn de du dɛn tɛst. Bɔt, risk de fɔ yuz dɛn tin ya, bikɔs yu nɔ go gɛt pɔsin fɔ tɔk to bɔt di rizɔlt wit yusɛf.

If yu tɛst pɔsitiv fɔ wan jenɛtik kɔndishɔn, ɔ if yu kam fɔ no se yu de pan risk fɔ gɛt wan sik, mek shɔ se yu tɔk to yu dɔktɔ. I kin rifer yu to pɔsin we de advays yu bɔt yu jɛnɛtiks. Da advaysa de kin evalyu yu ɛn di infɔmeshɔn we yu dɔn gɛt ɛn ɛp yu fɔ disayd wetin fɔ du nɛks.

Ustɛm dɛn bigin fɔ tɛst DNA?

Dis na stori bak we intrestin. Sayɛnsman dɛn bin mek wan tɛknik we dɛn kɔl `(Restriction Fragment Length Polymorphism - RFLP)` analisis insay di 1980 dɛm. Dis analisis na bin di fɔs jenɛtik tɛst we yuz DNA. Bɔt insay di 1990 dɛm, `(Polymerase Chain Riakshɔn - PCR)`Dɛn bin bigin fɔ du DNA tɛst. Dis PCR DNA testin mεtכd bin riples di fכs RFLP tεst mεtכd. Sayɛns fɔ tɛst DNA na tin we de chenj ɛn we de chenj ɔltɛm.

Wetin na DNA Paternity Test?

Yu go mɔs dɔn yɛri bɔt dis. DNA paternity test kin no udat na di biyolojikal papa fɔ pikin. DNA chɛk ɔ blɔd tɛst kin no if pɔsin na di biyolojikal papa fɔ yu pikin ɔ pikin. yu kin no dis bak we uman bεlε bay we yu du wan prεnatal paternity test.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Okay, so wi dɔn tɔk bɔku bɔt DNA tɛst, ɔ jenɛtik tɛst. Dɛn tɛst ya kin ɛp fɔ no if yu gɛt wan sik we de na yu jɛnɛtik ɔ if yu go gɛt wan patikyula sik tumara bambay. Pan ɔl we fɔ tɛst yu jɛnɛtiks kin gi yu sɔm pis na yu maynd , i kin kam bak wit bɔku prɔblɛm dɛn ɛn tin dɛn we yu nɔ kin ebul fɔ du .

If yu want fɔ tɛst yu jɛnɛtiks, mek shɔ se yu tɔk to yu dɔktɔ. I kin rifer yu to wan jenɛtik kɔlnɔ ɛn gi yu mɔ infɔmeshɔn bɔt di ɔl di prɔses.

Wi op se yu si se dis infɔmeshɔn go ɛp yu. If yu want fɔ no mɔ bɔt sɔntin lɛk dis, lɛ wi no!

` Jεnεtik tεst, DNA tεst, jεnεtik mכtεshכn, jεnεtik sik, prεnatal tεst, jεnεtik kכnsεl, paterniti tεst