Sɔntɛnde, we yu de na pati, we yu de wit yu padi dɛn, ɛn yu de drink smɔl wayn ɔ bia, dat nɔ kin mɔna sɔm pipul dɛn. Bɔt ɔda wan dɛn de, we ivin afta dɛn dɔn drink smɔl, dɛn fes kin rɛd ɔl ɛn dɛn nɔ kin fil fayn. Dat dɔn apin to yu? So, wi go tok abaut somtin we rili impotant to yu. Dat na wan kɔndishɔn we dɛn kɔl alcohol intolerance.
Wetin na fɔ drink rɔm?
Fɔ tɔk am simpul wan, dis na wan jenɛtik kɔndishɔn we wi kin gɛt frɔm wi mama ɛn papa, we gɛt fɔ du wit di we aw wi bɔdi de wok. Metabolism na di we aw wi bɔdi de tɔn it to ɛnaji. Na inhɛrit, we min se yu dɔn gɛt wan mutated jin frɔm yu mama ɛn papa ɔl tu. Sɔntɛm yu mama ɛn papa nɔ gɛt dis sik, bɔt dɛn kin pas da jin de to yu.
Wi bɔdi gɛt spɛshal prɔtin dɛn we dɛn kɔl ɛnzaym . Dɛn tin ya de ɛp wi fɔ dayjɛst di it we wi de it ɛn mek wi gɛt trɛnk. Di we aw wi nɔ de drink rɔm na prɔblɛm wit wan spɛshal ɛnzaym we de ɛp wi fɔ dayjɛst rɔm.
Dis na di rizin we mek ivin afta yu dɔn drink smɔl rɔm (ɛtanol), yu fes kin tɔn rɛd ɛn fil wam. Wi kin kɔl dis alkol flush . Dis kin kam wit wan filin wae nɔr kin fayn fɔ di bɔdi.
Nɔ kɔnfyus dis wit alɛji fɔ rɔm!
Bɔku pipul dɛn kin kɔnfyus dɛn tu tin ya. Bɔt dɛn tu tin ya na tu tin dɛn we rili difrɛn. I rili impɔtant fɔ ɔndastand dis kɔrɛkt wan.
Di we aw pɔsin nɔ de drink rɔm na prɔblɛm we de apin na di bɔdi we de mek pɔsin in jɛnɛtiks. Alɛji fɔ rɔm na di imyun sistɛm we de ansa.
Yu kin ɔndastand dis difrɛns izi wan frɔm di tebul we de dɔŋ ya.
| Tin | Di we aw pɔsin nɔ fɔ drink rɔm | Alɛji fɔ Alkol |
|---|---|---|
| Rizin | Wan jɛnɛtik prɔblɛm we gɛt fɔ du wit di dijestiv sistɛm. Di bɔdi nɔ kin ebul fɔ dayjɛst rɔm fayn fayn wan. | Wan ɔva-riakshɔn we di imyun sistɛm de du. di bכdi de riak to sכmtin we de insay di alkol (grεn, kεmikכl). |
| Men tin dɛn we de insay de | Flush, nɔs, ɛn at rit we de go ɔp. | Skin rash, bad bad it, swel, bɛlɛ pen. |
| Siriɔs tin we yu fɔ du | I nɔ kin fayn, bɔt bɔku tɛm i nɔ kin mek pɔsin in layf de pan denja. | I kin rili siriɔs ɛn ivin de mek pɔsin in layf de pan denja if dɛn nɔ trit am. |
As yu si, di sayn dɛm fɔ alɛji kin rili pen ɛn nɔr kin fil fayn. So if yu fil ɛnitin we nɔ kɔmɔn afta yu dɔn drink rɔm, nɔ ignore am. Mek shɔ se yu go to yu dɔktɔ fɔ advays.
Wetin mek dis de apin? Wetin na di rizin?
Fɔ ɔndastand dis, wi nid fɔ no smɔl bɔt aw rɔm kin brok insay wi bɔdi.
Dis na wetin kin apin we pɔsin drink rɔm (ɛtanol):
1. fכs step: wan εnzym we dεn kכl `alcohol dehydrogenase (ADH)` de brok dכn alkol.
2. Step 2: Di liva de chenj alkol to wan kemikal we dεn k כl asetaldehyde . Dis asetaldehayd na pɔyzin we kin pwɛl wi sɛl dɛn.
3. di tכd step: כda εnzym we dεn kכl `Aldehyde Dehydrogenase 2 (ALDH2)` de kam insay εn i de kכnvכlt da tכxik asetaldehayd de to aset asid we nכ de du bad (asetik asid - we dεn de fכnshכn bak insay vinega).
Naw lɛ wi si wetin kin apin to pɔsin we nɔ kin drink rɔm.
dεn gεt mכtεshכn na di jin we de mek di εnzym ALDH2, we de insay di tכd stεp. So dis ɛnzaym nɔ de wok fayn. Wetin kin apin da tɛm de? Da pɔyzin asɛtaldehayd de kin bɔku na di bɔdi. Na dat kin mek ɔl dɛn sayn dɛn de we nɔ fayn.
Wetin na di men sayn dɛm fɔ dis sik?
Di men sayn na we di fes de rɛd we dɛn kɔl alcohol flushing, bɔt bɔku ɔda sayn dɛn kin de.
| Di sayn we de sho se di sik de | Tɔk bɔt |
|---|---|
| Fɔ mek yu flash | Di fes, di nɛk, ɛn di chɛst kin rɛd ɛn fil wam. |
| Nɔs ɛn vɔmit | Nɔs ɛn vɔmit wit bɛlɛ diskɔmfɔt. |
| Di at we de blo | Fɔ fil lɛk se yu at de bit fast (tachycardia). |
| Lɔw blɔd prɛshɔn | Lɔw blɔd prɛshɔn (haypɔtɛnshɔn). |
| Ed de at | Ed we de at bad bad wan ɛn we de blo. |
| Nasal kɔnjɛshɔn | Wan filin fɔ stɔp na yu nos, lɛk kol. |
| Rɔnbɛlɛ | Bloating bikɔs ɔf prɔblɛm wit di dijestiv. |
| Di asma we de mek pɔsin wɔs | If yu gɛt asma, yu sik kin wɔs. |
Aw dɛn kin trit ɛn kɔntrol dis?
As wi bin dɔn tɔk, bikɔs dis na tin we pɔsin kin gɛt frɔm in bɔdi, no mɛrɛsin nɔ de fɔ am. Na tin we pɔsin kin gɛt fɔ ɔl in layf. Bɔt nɔ wɔri. Dɛn kin ebul fɔ manej am.
Di bɛst ɛn di wangren we fɔ du dat na fɔ lɛf fɔ drink rɔm kpatakpata. Dat na di simpul we fɔ mek di sik nɔ kam.
Apat frɔm dat, yu fɔ no bak bɔt dɛn tin ya:
- Nɔ smok: If yu smok, dat kin mek di asɛtaldehayd we de na di bɔdi go ɔp, ɛn dis kin mek yu gɛt kansa mɔ ɛn mɔ.
- Tek tɛm wit sɔm mɛrɛsin dɛn: Rɔk kin miks wit ɔda mɛrɛsin dɛn we yu de tek ɛn mek di sik dɛn we yu de gɛt wɔs. So tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
- Nɔ tek mɛrɛsin fɔ stɔp di sik: Sɔm pipul dɛn kin tek antasid ɔ antihistamin ɛn afta dat dɛn kin drink rɔm. Dis kin jɔs stɔp di sayn dɛm. Dɔn, we yu nɔ no, yu de drink mɔ rɔm. Dis kin mek di bɔdi pwɛl mɔ ɛn mɔ. Dis na abit we rili denja.
Wetin na de risk dɛm wae yu de drink rɔm pan dis sik?
Dis nɔto jɔs tin we nɔ izi fɔ du. If pɔrsin wae gɛt dis sik kɔntinyu fɔ drink rɔm, dɛn kin gɛt siriɔs sik.
Di bɔdi de gi wi wɔnin tru dɛn sik ya. If wi nɔ pe atɛnshɔn to da wɔnin de, dat kin mek wi gɛt siriɔs sik dɛn as tɛm de go.
Risach dɔn sho se pipul dɛm wae gɛt dis sik kin gɛt bɔrku risk fɔ gɛt dɛn tin ya if dɛn drink rɔm:
- Kansa na yu mɔt ɛn yu trot (kansa na yu ed ɛn nɛk) .
- Liva sik (liva sik lɛk sirosis) .
- Alzaima sik we kin bigin let
So, nɔ dismis yu fes fɔ tɔn rɛd ɔ yu bɔdi de wam afta yu dɔn drink smɔl rɔm as "oh, dat na nɔmal tin." Na impɔtant signal we yu bɔdi de gi yu.
Mɛsej we dɛn kin kɛr go na os
- If pɔsin nɔ drink rɔm na sɔntin we pɔsin kin gɛt frɔm in jɛnɛtiks, nɔto alɛji.
- dis de bi fכ di dכn aktiviti fכ di εnzym ALDH2 we de mek tכxik asetaldehayd de kכmכt na di bכdi.
- Di men sayn na fɔ fil wam ɛn rɛd na yu fes, nɛk, ɛn chɛst afta yu dɔn drink rɔm. Apat frɔm dat, sɔm sayn dɛn lɛk fɔ nɔs ɛn ed we de at kin apin bak.
- Di bɛst ɛn sef we fɔ mɛn dis sik na fɔ lɛf fɔ drink rɔm ɔltogɛda.
- If yu nɔ pe atɛnshɔn to dis tin ɛn drink rɔm, dat kin rili mek yu gɛt siriɔs sik dɛn lɛk kansa na yu mɔt ɛn sik na yu liva.
- If yu gɛt ɛni wan pan dɛn tin ya we nɔ fayn we yu de drink rɔm, tɔk to yu dɔktɔ bɔt am.
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