We ol pɔsin na wi os, dat na wi mama, papa, grani ɔ granpa, bigin fɔ fɔgɛt tin smɔl smɔl, ɛn we dɛn aks di sem tin ɔltɛm, smɔl fred kin kam na wi at, nɔto so? Di kwɛshɔn "Na dis na di biginin fɔ Alzaima sik?" de mek wi wɔri. Infakt, we wi yɛri Alzaima sik, wetin kin kam na wi maynd na sɔri tin we kin mek wi nɔ ebul fɔ mɛmba smɔl smɔl, wi nɔ kin ebul fɔ du ivin wok dɛn we wi sabi, ɛn leta wi kin fɔgɛt udat wi bi. Na tru dat. Bɔt yu no se bɔku men kayn dis sik de, i kin dipen pan di we aw i kin kam, dat na di ej we di sik bigin ɛn di tin dɛn we kin mek i sik? Lɛ wi tɔk bɔt dis jɔs tide.
Pan ɔl we di kayn sik kin difrɛn, di kɔmɔn sayn dɛm na di sem.
Fɔs, lɛ wi ɔndastand dis. I nɔ mata di kayn Alzaima sik, di sayn dɛm wae ɔlmost ɔl di sik pipul dɛm kin gɛt as tɛm de go, kin rili fiba.
- Memori lɔs: Fɔ fɔgɛt tin dɛn, mɔ di wan dɛn we dɛn jɔs dɔn mek.
- Kɔnfyushɔn: Kɔnfyushɔn bɔt tin dɛn lɛk tɛm, ples, ɛn de.
- I nɔ izi fɔ du wok dɛn we yu sabi: I nɔ izi fɔ du ivin simpul wok dɛn lɛk fɔ mek ti ɔ fɔ wɛr klos yu wan.
- I nɔ izi fɔ disayd fɔ du sɔntin: Fɔ fil se yu dɔn lɔs, yu nɔ ebul fɔ disayd ivin simpul wan.
di כndalayn kכz fכ כl dis na di akyumyuleshכn fכ wan kayn protin we dεn kכl `amyloid beta peptides` insay di nεv sεl dεm na wi bren. Fɔ tɔk am simpul wan, dis tan lɛk wan kayn "garbage" we kin gɛda na di bren. Nɔmal wan, wi bren kin pul dis kayn tin we nɔ nid. Bɔt pan Alzaima sik, dis prɔses nɔ kin apin fayn fayn wan. afta dat dεn protin dεm ya kin kכmכt εn fכm plek εn tכngl dεm na di bren. Bikɔs ɔf dis, di tin dɛn we de flɔ bitwin di bren sɛl dɛn kin stɔp, ɛn di sɛl dɛn kin day smɔl smɔl. I nɔ mata uskayn sik, dis prɔses kin kɔmɔn.
De tu men kayn sik wae de kam wit Alzaima
Dipen pan di ej we i bigin, wi kin sheb am to tu men kayn. Si di tebul we de dɔŋ fɔ ɔndastand di difrɛns bitwin dɛn tu kayn ya.
| Tin | Alzaima we kin bigin kwik kwik wan | Alzaima we kin bigin let |
|---|---|---|
| Di ej we di sik bigin | I nɔ rich 65 ia yet. Usually in dem 40s-50s. | 65 ia ɔ pas dat. |
| Kɔmɔn tin | I nɔ kin apin so ɔltɛm, i kin apin pan less dan 5% pan ɔl di pasɛnt dɛn. | Dis na di kayn we we pipul dɛn kin gɛt mɔ. |
| Di pɔsibiliti fɔ pas pan jɛnɛreshɔn dɛn | Bɔku tɛm, wan strɔng jɛnɛtik link de. | I kin divɛlɔp ilɛksɛf sɔmbɔdi na di famili gɛt am ɔ nɔ gɛt am. Dɛn nɔ dɔn no di patikyula jin yet. |
| Bren kin chenj | yu kin si mכr plek dεm εn tangle dεm na di bren. Na mɔ bren de shrinkage. | Ivin if chenj na di bren, i kin bi smɔl smɔl tin. |
| Ɔda tin dɛn we de apin | yu kin si di mכsul dεm we de twit/jεk (myoclonus) wan wan. | Di mɛmori lɔs de kɔmɔt as di men sayn. |
Alzaima we kin bigin kwik kwik wan
Dis kin mek yu sɔprayz smɔl. Bɔt yes, sɔm pipul dɛn kin gɛt Alzaima sik we dɛn ol 40 ɔ 50 ia. Dis na tin we nɔ kin apin so ɔltɛm. Na bikɔs ɔf di tin dɛn we nɔ fayn na di jɛnɛtiks . spεshal wan, dεn fכnshכn se dis kכndyushכn de kכz fכ difεkt dεm na di kromozom 1, 14, εn 21, we gεt jεnεtik infכmeshכn na wi bכdi. Dɔn bak, pipul dɛm wae gɛt Daun sindrom kin gɛt dis kayn Alzaima sik.
Alzaima we kin bigin let
Dis na de kayn Alzaima wae wi ɔl no. Bɔrku tɛm, de sik kin bigin fɔ sho afta yu dɔn ol 65. Sɔmtɛm e kin rɔn na famili. Dis min se if mama gɛt am, in pikin kin de pan denja. Bɔt wan patikyula jin, lɛk di kayn we de divɛlɔp we i yɔŋ, .Dɛn nɔ dɔn no yet di rayt tin we kin mek dis sik kam. So, dɔktɔ ɛn sayɛnsman dɛn stil de du risach bɔt wetin mek sɔm pipul dɛn kin gɛt am ɛn ɔda wan dɛn nɔ kin gɛt am.
Wetin na Famili Alzaima Disease (FAD)?
Somtin de we plenti pipul kin konfuz boht ya. "Sɔmbɔdi na di famili bin gɛt am" ɛn "Familial Autism Spectrum Disorder (FAD)" na tu difrɛn tin dɛm.
Famili Alzaima Disease (FAD) na wan sik wae dɔktɔ dɛn 100% shɔ se na bikɔs ɔf jɛnɛtiks. Fɔ mek dɛn no se i gɛt am, at le tu jɛnɛreshɔn dɛn na di famili (fɔ ɛgzampul, wan grani ɛn wan mama) fɔ dɔn gɛt dis sik. I nɔ kin apin so ɔltɛm, i kin mek i nɔ rich 1% pan ɔl di wan dɛn we gɛt Alzaima. Bɔrku pipul dɛm wae gɛt Alzaima wae dɛn yɔŋ kin gɛt dis kayn FAD.
If yu ɔ sɔmbɔdi na yu famili gɛt prɔblɛm wit mɛmori, nɔ jɔs tink se, "Dis na jɔs ol-fashin tin" ɔ "na jɔs famili istri." I kin bi wan sik we pɔsin kin trit. So di bɛst tin fɔ du na fɔ go to yu dɔktɔ kwik kwik wan ɛn gɛt di rayt diagnosis.
Mɛsej we dɛn kin kɛr go na os
- Alzaima sik kin kam difrɛn kayn we. Dis klasification de men wan bay di ej wae di sik bigin (early-onset and let-onset).
- De kayn wae kin bigin kwik kwik wan, wae kin kam pan pipul dɛm wae nɔr rich 65 ia, nɔr kin bɔrku. I gɛt strɔng jɛnɛtik link.
- wan patikyula jεnεtik kכz dεn nכ dכn fכnshכn yet fכ di let-onset tכp we wi kin si mכst, we de divεlכp afta di ej 65.
- Nɔ tink se jɔs bikɔs pɔsin na yu famili gɛt Alzaima, yusɛf go gɛt am. Bɔt i impɔtant fɔ no bɔt di prɔblɛm we kin apin.
- If yu gɛt ɛni prɔblɛm we gɛt fɔ du wit mɛmori, fɔ go to dɔktɔ wantɛm wantɛm pas fɔ nɔ pe atɛnshɔn to am, dat kin rili ɛp di pɔsin ɛn di famili.
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