Sɔm sik, fɔ ɛgzampul, pipul dɛn we gɛt sik lɛk Thalassemia, kin gɛt fɔ gi blɔd to di bɔdi ɔltɛm. We wi gɛt blɔd fɔ lɔng tɛm lɛk dis, di ayɛn lɛvɛl na wi bɔdi kin go ɔp we wi nɔ nid. Wi de kɔl dis ayɛn ɔvalod. Dis ayɔn we dɔn bɔku kin de na impɔtant ɔgan dɛn lɛk wi at ɛn liva ɛn pwɛl dɛn. So, wan spɛshal mɛrɛsin we dɔktɔ dɛn kin yuz fɔ pul dis aynɔ we pasmak na di bɔdi, dɛn kɔl am Deferasirox. Lɛ wi tɔk bɔt dis tide.
Wetin na Deferasirox? Wetin i rili de du?
Fɔ tɔk am simpul wan, dis mɛrɛsin we dɛn kɔl Deferasirox de wok lɛk magnet. I kin atak di ayɛn pat dɛn we wi nɔ want, we pasmak na wi blɔd, kech dɛn, ɛn ɛp fɔ pul dɛn kɔmɔt na di bɔdi. Dɛn kɔl dis prɔses Chelation insay mɛdikal sayɛns. Dis kin mek wi nɔ gɛt di damej we di ayɛn we pasmak kin mek wi impɔtant pat dɛn. Dis mɛrɛsin kin kam ɔnda brand nem lɛk Jadenu.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin
Yu dɔktɔ fɔ no bɔt yu kɔmplit wɛlbɔdi istri bifo yu gi yu dis mɛrɛsin. Mek shɔ se yu tɛl dɛn bɔt ɛni wan pan dɛn tin ya, mɔ if yu gɛt dɛn:
- If yu gɛt ɛni kansa.
- If yu nɔ de si fayn ɔ yu gɛt sik dɛn na yu yay.
- If yu gɛt ɛnitin we nɔ de yɛri fayn.
- If yu gɛt sik na yu kidni ɔ yu gɛt liva sik.
- If yu gɛt wan sik we de mek di nɔmba fɔ di wayt blɔd sɛl, di pletlɛt, ɔ di rɛd blɔd sɛl dɛn we de na di blɔd (blɔd kɔnt smɔl).
- If yu gɛt alɛji to dis Deferasirox mɛrɛsin ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ.
Dɛn fɔ yuz di mɛrɛsin di rayt we.
I rili impɔtant fɔ fala di rayt instrɔkshɔn fɔ yuz dis mɛrɛsin.
- Tek am ɛmti bɛlɛ: Yu fɔ tek dis mɛrɛsin we yu ɛmti bɛlɛ . Dat min se, at le 30 minit bifo yu it, ɔ 2 awa afta yu it.
- Tek am di rayt tɛm: Tek di doz we dɛn tɛl yu fɔ tek di tɛm we yu dɔktɔ tɛl yu. Nɔ tek pas di nɔmba we dɛn tɛl yu fɔ tek fɔ wan de.
- Nɔ stɔp: Nɔ stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm if yu dɔktɔ nɔ advays yu.
We dɛn gi am to smɔl pikin dɛn
Dɛn kin gi dis mɛrɛsin to pikin dɛn we dɔn pas 2 ia pan sɔm kes dɛm we dɛn dɔn pik. Bɔt na yu pikin in dɔktɔ go disayd dis. So, if yu de gi pikin dis mɛrɛsin, fala di dɔktɔ in instrɔkshɔn dɛn gud gud wan.
Wetin a go du if a mis wan doz fɔ tek mɛrɛsin?
If yu mis wan doz, tek am jɔs afta yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul.Nɔ ɛva tek tu dos wan tɛm.
Wetin a go du if a tek bɔku mɛrɛsin?
Imajin se yu dɔn tek bɔku mɛrɛsin di rɔng tɛm. If dat apin, nɔ panik ɛn kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital wantɛm wantɛm . Ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Ɔda mɛrɛsin dɛm wae kin intarakt wit Deferasirox
Dis mɛrɛsin kin miks wit sɔm ɔda mɛrɛsin dɛm, so i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl ɔda mɛrɛsin dɛm we yu de tek (inklud vaytamɛn ɛn ɛbul mɛrɛsin dɛm).
| Tayp fɔ mɛrɛsin | Diskripshɔn ɛn ɛgzampul dɛn |
|---|---|
| Tin dɛn we yu nɔ fɔ rili tek wit dis mɛrɛsin | |
| Ayɔn sɔpɔtmɛnt dɛn | If yu tek dis mɛrɛsin, i go pul di ayɛn we pasmak na di bɔdi, so if yu tek ayɔn tablɛt na do, i nɔ go ɛp. |
| Sɔm mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn Epataytis C | Fɔ ɛgzampul: Dasabuvir, Ombitasvir, Paritaprevir, Ritonavir |
| Ɔda mɛrɛsin dɛm wae kin mek yu gɛt intarakshɔn (tɛl yu dɔktɔ if yu de tek dɛn wan ya) . | |
| Di tin dɛn we de mek pɔsin nɔ gɛt asid | Mɛrɛsin fɔ gastritis we gɛt aluminiɔm. |
| Di tin dɛn we dɛn kin yuz fɔ mɛn pen (NSAID) . | Fɔ ɛgzampul: Mɛrɛsin dɛn lɛk Ibuprofen ɛn Naproxen. |
| Pils dɛn we dɛn kin yuz fɔ kɔntrol pikin | Dis mɛrɛsin kin mek di pils fɔ kɔntrol pikin nɔ wok fayn. |
| Ɔda mɛrɛsin dɛn | Bɔku ɔda mɛrɛsin dɛn, lɛk mɛrɛsin dɛn we de mek pɔsin nɔ gɛt bɔku kɔlɔstrel (Cholestyramine, Simvastatin), mɛrɛsin dɛn we de mek pɔsin sik (Phenobarbital), we de mek blɔd tan (Warfarin), stɛroyd (Prednisone), Cyclosporine, Rifampin, ɛn ɔda wan dɛn. |
Tek kia ɔf yu bɔdi we yu de tek mɛrɛsin.
I rili impɔtant fɔ pe atɛnshɔn to di chenj dɛn we de apin na yu bɔdi we yu de tek dis mɛrɛsin.
Siriɔs Riakshɔn na di Skin: Sɔntɛnde dis mɛrɛsin kin mek pɔsin gɛt siriɔs riakshɔn na di skin. Dis kin apin ivin sɔm wiks afta yu dɔn bigin fɔ tek di mɛrɛsin. If yu gɛt rɛd rash wit fiva, yu bɔdi de at, if i tɔn pepul ɛn blista, if yu skin kɔmɔt, ɔ if yu gɛt rɛd rash wit bɔmp na yu nɛk ɔ yu armpit , go to dɔktɔ wantɛm wantɛm.
- Mɛdikal tɛst: Yu dɔktɔ go chɛk yu yay, yɛri, ɛn blɔd (especially kidney ɛn liva function) bifo yu bigin tek dis mɛrɛsin ɛn we yu de tek am. Nɔ skip dɛn tɛst ya.
- Bɛlɛ we de kɔmɔt na yu bɛlɛ: If yu gɛt blak, tar stɔl, ɔ yu vɔmit we tan lɛk kɔfi grɔn, i kin bi sayn fɔ se yu de blɔd bikɔs ɔf ɔlsa na yu bɛlɛ ɔ yu intestinal. If dis apin, tɛl dɔktɔ wantɛm wantɛm.
- Diziz: Dis mɛrɛsin kin mek sɔm pipul dɛn diziz. Nɔ drayv ɔ yuz mashin te yu no aw dis mɛrɛsin de afɛkt yu. Tek tɛm we yu de grap ɔ sidɔm wantɛm wantɛm.
- Di wata we de na pikin dɛn: If dɛn gi yu pikin dis mɛrɛsin ɛn in bɛlɛ de at bad bad wan, i de vɔmit, ɔ i de swet pasmak, tɛl yu dɔktɔ wantɛm wantɛm. Fɔ gi dis mɛrɛsin kin denja if di bɔdi lɔs bɔku wata (dehydration).
Sayd ɛfɛkt dɛm wae kin kam wit dis mɛrɛsin
Lɛk ɛni mɛrɛsin, Deferasirox kin mek yu gɛt sayd ɛfɛkt. Sɔm pan dɛn siriɔs, ɛn ɔda wan dɛn kin kɔmɔn.
| Sayd ɛfɛkt we pɔsin kin gɛt | Tɔk bɔt |
|---|---|
| Siriɔs sayd ɛfɛkt dɛm we dɛn fɔ ripɔt to di dɔktɔ wantɛm wantɛm | |
| Siriɔs alɛji dɛn | Skin rash, it, swel na di fes, lip, tong, i nɔ izi fɔ blo. |
| Di sayn dɛm we de sho se di liva dɔn pwɛl | di skin ɔ yay we de yɔlɔ, dak yɔlɔ/brawn urine, pen na di ɔp rayt say na di bɛlɛ, we yu nɔ de want fɔ it, we yu taya pasmak. |
| Di sayn dɛm we de sho se di kidni dɔn pwɛl | Di urine autput we de dכn, i at fכ urine. |
| Chenj we yu de si ɔ yɛri | Yu nɔ de si fayn, yu nɔ de yɛri fayn. |
| Blɔd we nɔ de kɔmɔt fayn | Brus ɛn blɔd we nɔ nid fɔ de na di skin. |
| Kɔmɔn sayd ɛfɛkt dɛm wae yu fɔ ripɔt to yu dɔktɔ if dɛn kɔntinyu ɔr de mɔna yu: | |
| Prɔblɛm dɛn we de na di dijestiv sistɛm | Bɛlɛ pen, dayarɛa, nɔs, vɔmit. |
| Nɔ ebul slip | I nɔ kin izi fɔ mek yu slip. |
Mɛsej we dɛn kin kɛr go na os
- Deferasirox na mɛrɛsin we dɛn kin gi fɔ pul di aynɔ we pasmak na di bɔdi. Dɛn fɔ tek am jɔs lɛk aw di dɔktɔ tɛl am, pan ɛmti bɛlɛ.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek, mɔ di wan dɛn we de mɛn pen ɛn di wan dɛn we de mek yu nɔ gɛt asid, bikɔs dis mɛrɛsin kin miks wit ɔda mɛrɛsin dɛn.
- If yu gɛt siriɔs sayn dɛn lɛk we yu skin de rɔsh, blak stɔl, ɔ yu yay we yɔlɔ, go to dɔktɔ wantɛm wantɛm.
- We yu de tek dis mɛrɛsin, mek shɔ se yu du tɛst fɔ yu blɔd, yu yay, ɛn yes we yu dɔktɔ tɛl yu fɔ du.
- Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ ɛva sheb am wit ɔda pipul dɛn.
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