Bɔku pipul dɛn na mi famili dɔn gɛt kansa... so a go gɛt am bak? Dis fred, dis kweshon na somtin we de fo plenti of wi maind. Wi dɔn yɛri se sɔm kayn kansa kin pas frɔm jɛnɛreshɔn to jɛnɛreshɔn, dat min se dɛn kin kɔmɔt frɔm jin, nɔto so? Wɛl, tide wi go tɔk bɔt wan spɛshal we we go ɛp yu fɔ no if yu gɛt kansa we yu kin gɛt frɔm yu mama ɛn papa.
Wetin na dis jenɛtik tɛst?
Fɔ tɔk am simpul wan, dis na tɛst we de luk di DNA we de na wi bɔdi. Tink bɔt wi bɔdi as big buk we de tich wi. Dis buk de tɛl ɔl di sɛl dɛn na wi bɔdi aw fɔ wok, aw dɛn fɔ sheb, ɛn ustɛm dɛn fɔ day. Dɛn instrɔkshɔn ya na wetin wi kɔl jin .
Sɔntɛnde, tayp ɔ ɔda mistek dɛn kin de na dis gayd. We wi de tɔk bɔt mɛrɛsin, wi kin kɔl dɛn tin ya we kin mek pɔsin chenj in jɛnɛtiks . kansa kin apin we di nכmal sεl dεm bigin fכ divayd we dεn nכ kin kכntro bikoz fכ dis kayn jεnεtik mכtεshכn.
Bɔku tɛm, dɛn nɔ kin gɛt dɛn jɛnɛtik chenj ya we kin mek pɔsin gɛt kansa. כltu, bitwin 5% εn 10% pan כl di kεnsar dεm na di jεnεtik mכtεshכn we wi kin gεt frכm wi mama εn papa. Fɔ tɛst yu jɛnɛtiks na fɔ tek wan sɛmpul pan yu blɔd ɔ saliva ɛn luk fɔ wan jenɛtik mutation na yu bɔdi.
Bɔt mɛmba dis. Ivin if dis tɛst sho se yu gɛt wan jenɛtik muteshɔn we de mek yu gɛt kansa mɔ, i nɔ min se yu go mɔs gɛt kansa. I jɔs min se yu ‘risk’ fɔ gɛt kansa pas ɔda pipul dɛn smɔl.
Wan pɔsin we de advays yu bɔt yu jɛnɛtiks kin ɛksplen to yu klia wan aw dɛn tin ya we kin apin kin afɛkt yu wɛlbɔdi.
Us kayn kansa dɛn kin gɛt frɔm dɛn mama ɛn papa?
Bɔku kayn kansa de we pɔsin kin gɛt bikɔs ɔf di chenj we pɔsin kin gɛt frɔm in jɛnɛtiks. Di men wan dɛn na:
- Brɔst kansa
- Kansa na di kɔlon
- Kidni kansa
- Kansa na ovarian
- Kansa na di pankrias
- Prɔstat kansa
- Bɛlɛ kansa
- Tayrɔyd kansa
- Kansa na di uterin
Dɛn jenɛtik tɛst ya nɔ de tɛst fɔ gɛt kansa. Bifo dat, dɛn kin tɛst fɔ no sɔm patikyula tin dɛn we de na di jɛnɛtiks we kin mek pɔsin gɛt kansa. Sayɛnsman dɛn dɔn no te naw, pas 400 jin dɛn we gɛt fɔ du wit kansa we pɔsin kin gɛt frɔm in mama ɛn papa. Wi kin sheb dɛn grup ya to tri men grup dɛn.
| Jɛnɛtiks | Fɔ tɔk am simpul wan, wetin yu de du | Wetin kin apin we i kin chenj? |
|---|---|---|
| Di jin dɛn we de stɔp di tumor Eks: BRCA, P53 jin dɛn | Dɛn tin ya tan lɛk di ‘brek’ we motoka kin yuz. Dɛn wok na fɔ stɔp di kansa sɛl dɛn we de gro. | Jɔs lɛk aw motoka nɔ kin ebul fɔ stɔp we di brek dɛn stɔp fɔ wok, we dɛn chenj dɛn jin ya, di kansa sɛl dɛn kin gro we dɛn nɔ ebul fɔ kɔntrol. |
| Proto-ɔnkojin dɛn | Dɛn tin ya tan lɛk di ‘accelerator’ we de insay motoka. Dɛn kin ɛp di sɛl dɛn fɔ gro na di nɔmal rit, as nid de. | Jɔs lɛk aw we di aksilarayt jam, dɛn nɔ kin ebul fɔ kɔntrol di spid we di motoka de spid, we dɛn chenj dɛn tin ya, di kansa sɛl dɛn kin gro kwik kwik wan. |
| DNA ripa jin dɛn | Dɛn tin ya tan lɛk di ‘garaj’ usay dɛn de mek motoka. Dɛn kin mek mistek ɛn damej we kin apin na wi DNA. | Jɔs lɛk aw dɛn nɔ kin ebul fɔ mek motoka we dɛn lɔk di garaj, we dɛn chenj dɛn jin ya, dɛn nɔ kin ebul fɔ mek mistek pan DNA, ɛn dis kin mek kansa kam. |
Udat want fɔ du dis kayn tɛst?
If yu dɔktɔ tink se yu kin gɛt kansa frɔm yu mama ɛn papa bay yu yon mɛdikal istri ɔ yu famili mɛdikal istri, i kin tɛl yu fɔ du dis tɛst.
Akɔdin to yu pasɔnal mɛdikal istri:
- If yu dɔn gɛt bɔku difrɛn kayn kansa dɛn .
- If yu bin gɛt kansa we yu bin rili yɔŋ .
- If dɛn dɔn no se pɔsin we yu ej ɔ yu man ɔ uman gɛt wan kayn kansa we nɔ kɔmɔn .
- insay di tu כgan dεm we de pe , lεk tu kidni dεm εn tu brεst dεmIf yu gɛt kansa.
- If yu gɛt ɔda sayn dɛm wae gɛt fɔ du wit sɔm kayn kansa wae yu kin gɛt (fɔ ɛgzampul, pɔrsin wae gɛt Nyurofibromatosis Tayp 1 kin gɛt lumps bak wae nɔr gɛt kansa).
Akɔdin to yu famili mɛdikal istri:
- If sɔm pipul dɛn na yu famili dɔn gɛt di sem kayn kansa .
- If sɔm pipul dɛn na di famili dɔn gɛt kansa we dɛn yɔŋ .
- If sɔm fambul dɛm na di sem say na di famili dɔn gɛt di sem kayn kansa (e.g., na di mama in sayd).
- If dɛn dɔn ɔlrɛdi no se pɔsin na yu famili gɛt wan sik we de mek yu gɛt kansa.
"A klos fambul" kin konfuz likli, no bi so? Bɔku tɛm, dɔktɔ dɛn kin tek yu fambul dɛn we na yu fɔs digri pas ɔlman. Dat min se yu mama, yu papa, yu brɔda ɛn sista dɛn, ɛn yu pikin dɛn . Bɔt sɔntɛnde, di mɛdikal istri fɔ di fambul dɛn we de fa fawe kin impɔtant bak.
If yu nɔ shɔ if yu nid dis tɛst ɔ yu nɔ nid fɔ du am, i go fayn fɔ mek yu tɔk to yu dɔktɔ ɔ pɔsin we de advays yu bɔt yu jɛnɛtiks bɔt am .
Aw dɛn kin du dis tɛst?
Di fɔs ɛn impɔtant tin we yu fɔ du bifo yu du dis tɛst na fɔ advays yu bɔt yu jɛnɛtiks . Wan spɛshal pɔsin we tren fɔ advays yu go ɛksplen ɔltin to yu.
- Yu tink se dis tɛst rili rayt fɔ yu?
- Wetin na di tɛst we go fayn fɔ yu fɔ du?
- Wetin na di bɛnifit ɛn bad tin dɛn we dis tɛst gɛt?
- Di tin dɛn we kin apin kin afɛkt yu wɛlbɔdi ɛn layf.
- Aw dɛn tin ya we kin apin kin afɛkt yu famili?
Afta yu dɔn tɔk bɔt ɔl dis, dɛn kin du di tɛst bay wetin yu want. Bɔku tɛm, dɛn kin tek blɔd sɛmpul ɔ saliva sɛmpul frɔm yu ɛn sɛn am na lɛbɔtri. Na de, tɛknishian dɛn kin chɛk yu jin fɔ si if i chenj. We di rizɔlt dɔn kam, dɛn kin sɛn di ripɔt to yu dɔktɔ.
Yu go dɔn si tɛst kit dɛn na os. Bɔt di rizɔlt dɛn we dɛn kin gi nɔ kin kɔmplit ɔ kɔrɛkt ɔltɛm. Dɔn bak, we dɛn du am tru dɔktɔ , lɔ de protɛkt di kɔnfidɛns fɔ yu mɛrɛsin infɔmeshɔn . So i bɛtɛ ɔltɛm ɛn i bɛtɛ fɔ du dis we yu tɔk to dɔktɔ ɔ pɔsin we de advays yu bɔt yu jɛnɛtiks .
Bɔrku tɛm, i kin tek lɛk tu ɔ tri wiks fɔ gɛt di rizɔlt.
Aw fɔ ɔndastand di ansa dɛn we de na di tɛst ripɔt?
Dɛn kin sheb di tin dɛn we dɛn dɔn fɛn to tri men kategori.
| Rizɔlt | Wetin dis min? |
|---|---|
| Gud | Dɛn dɔn no se yu gɛt wan tin we de chenj na yu jɛnɛtiks we de mek yu gɛt kansa mɔ ɛn mɔ. Dat nɔ min se yu go mɔs gɛt kansa, bɔt di risk kin bɔku . |
| Bad | Di jin dɛn we dɛn bin tɛst nɔ bin fɛn wan muteshon we de mek di risk fɔ gɛt kansa bɔku. If yu no se sɔmbɔdi na yu famili gɛt dis muteshon, bɔt yu nɔ gɛt am, dɛn kin kɔl am "tru negatif." |
| Variant of Ɔnsatayn Sigifikɛns (VUS) . | Dɛn dɔn si wan chenj (muteshɔn) na yu jin, bɔt sayɛnsman dɛn nɔ shɔ yet if i de mek yu gɛt kansa mɔ. E kin bi nɔmal, nɔr bad chenj, ɔr e kin bi wan wae dɛn kin si se gɛt fɔ du wit kansa tumara bambay. |
Wetin yu kin du afta yu dɔn gɛt di rizɔlt?
Ilɛk wetin yu go du, di pɔsin we de advays yu bɔt yu jɛnɛtiks go tɔk to yu bɔt am ditayli. If di rizɔlt na fayn tin , yu go tɔk bɔt:
- Chenj dɛm to yu wɛl bɔdi plan: Tɔk bɔt spɛshal skrinin fɔ no if yu gɛt kansa kwik kwik wan, lɛk fɔ du mamogram ɔr kɔlon skɔpi ɔltɛm, ɛn tin dɛm wae yu kin du fɔ ridyus yu risk fɔ gɛt kansa.
- Famili planin: Dɛn kin tɔk bɔt dis jɛnɛtik muteshon pan di chans fɔ pas am to yu pikin.
- Fɔ notis yu famili: Dis go tɔk bɔt aw di rizɔlt go afɛkt yu blɔd fambul dɛm (mama ɛn papa, brɔda ɛn sista, pikin dɛm) ɛn di step dɛm we dɛn fɔ tek.
Ivin if di rizɔlt nɔ fayn ɔ VUS , yu go nid fɔ go to yu dɔktɔ bɔku tɛm ɔ du ɔda tɛst. If nyu sayɛns infɔmeshɔn kam bɔt VUS rizɔlt, yu dɔktɔ go mek yu no.
Wetin na di bɛnifit ɛn prɔblɛm dɛn we dis tɛst gɛt?
Lɛk ɛni tɛst we dɛn kin du fɔ mɛn pipul dɛn, dis wan gɛt bɛnifit dɛn ɛn sɔm prɔblɛm dɛn bak.
| Bɛnifit dɛn | Disavantej / Chalenj dɛn |
|---|---|
| Di fred ɛn di tin dɛn we a nɔ bin no wetin fɔ du na mi at kin dɔn ɛn a kin fil sɔm kayn fridɔm. | Fɔ fred, wɔri, ɛn strɛs we nɔ nid fɔ apin bɔt di tin dɛn we kin apin kin apin. |
| Yu kin tek step fɔ ridyus di risk fɔ gɛt kansa ɛn no am kwik. | If yu tɛl yu famili bɔt dis, dat kin afɛkt yu padi biznɛs. |
| Yu dɔktɔ go ɛp yu fɔ mek wan wɛlbɔdi plan we go spɛshal fɔ yu. | Fɔ fil gilti kin kɔmɔt frɔm sɔntin we pɔsin kin gɛt frɔm am. |
| Yu famili kin gɛt di chans bak fɔ no bɔt dɛn wɛlbɔdi prɔblɛm dɛn. | Di tɛst kin tek sɔm mɔni. |
Wan jenɛtik kɔlnɔ kin ɛp yu fɔ dil wit dɛn filin ya we de mek yu fil ɛn gayd yu fɔ aw fɔ tɔk to yu famili bɔt dis, na dat mek i impɔtant fɔ gɛt dɛn sɔpɔt ɔlsay na dis prɔses.
Mɛsej we dɛn kin kɛr go na os
- Wan jenɛtik tɛst fɔ kansa nɔ de tɛl yu se yu gɛt kansa, na bɔt di risk we yu gɛt frɔm yu mama ɛn papa fɔ gɛt kansa.
- I rili impɔtant fɔ tɔk to pɔsin we de advays yu bɔt yu jɛnɛtiks bifo ɛn afta yu gɛt di rizɔlt fɔ dis tɛst.
- Ivin if di rizɔlt na pɔsitiv, nɔ panik ɛn tek di step dɛm we nid fɔ ridyus yu risk ɛn no bɔt kansa kwik, lɛk aw yu dɔktɔ se.
- Fɔ tɔk opin wan ɛn ɔnɛs wit yu dɔktɔ bɔt yu famili in kansa istri na wan pan di bɛst tin dɛn we yu go du fɔ protɛkt yu wɛlbɔdi.
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