Yu dɔn ɛva yɛri se wi yon bɔdi in difɛns sistɛm, di sistɛm we de protɛkt wi frɔm sik, sɔntɛnde kin wok agens wi? Ɔ se afta dɛn dɔn transplant pɔsin, lɛk kidni, in bɔdi kin tray fɔ nɔ gri fɔ tek di nyu ɔgan? Tide, wi go tɔk bɔt wan spɛshal klas ɔf drɔgs we dɔktɔ dɛn kin gi fɔ kɔntrol aw wi imyun sistɛm de wok pan dɛn kayn siriɔs kes ya.
Wetin na dɛn tin ya we de mek pɔsin nɔ ebul fɔ fɛt di sik?
Fɔ tɔk am simpul wan, dɛn mɛrɛsin ya de ridyus ɔ stɔp di wok we yu bɔdi in imyun sistɛm de du. Nɔmal wan, wi imyun sistɛm tan lɛk ami we de protɛkt wan kɔntri. We i si fɔrina ɛnimi dɛn, lɛk vayrɔs, baktri, ɛn kansa sɛl, dis ami kin fɛt ɛn protɛkt wi.
Bɔt sɔmtɛm, dis ami kin mek mistek ɛn bigin fɔ atak wi yon wɛlbɔdi sɛl ɛn tisu dɛn, ɛn tink se, "Dis na ɛnimi dɛn bak." Na dɛn kayn tɛm ya, wi kin gi dɛn immunosuppressants ya fɔ mek di ami we de wok pasmak kol.
Bɔt di tin we impɔtant pas ɔl fɔ mɛmba na dat bikɔs dɛn mɛrɛsin ya de mek di imyun sistɛm wik, di risk fɔ gɛt infɛkshɔn frɔm vayrɔs ɛn baktri dɛn kin rili bɔku.
Us sityueshɔn dɛn kin yuz dɛn mɛrɛsin ya?
Dɔktɔ dɛn kin tɛl dɛn fɔ tek dɛn mɛrɛsin ya mɔ pan tu tin dɛn.
1. Fɔ Ɔtoimyun Sik dɛn
Dis na di kɔndishɔn we wi yon imyun sistɛm de atak wi. we dis apin, di hεlty sεl dεm na di bכdi kin pwεl εn inflameshn kin bigin fכ apin. Dɛn mɛrɛsin ya kin stɔp di atak we dɛn nɔ want we di imyun sistɛm kin atak ɛn kɔntrol di sik dɛn. Dɛn mɛrɛsin ya kin ivin kɔntrol sɔm sik dɛn kpatakpata ɛn put dɛn na rɛmishɔn we nɔ gɛt ɛni sayn.
Sɔm pan di ɔtoimyun sik dɛm wae dɛn kin yuse dis mɛrɛsin fɔ na:
- Patchy ia we de lɔs (Alopecia areata) .
- Inflammatory bowel disease, lɛk Crohn’s disease ɛn ɔlsa kɔlayt
- Lupus we gɛt di sik
- Mɔltipɛl sklɛrosis (MS) .
- Psoriasis ɛn at at sik we gɛt fɔ du wit am
- Rimatɔyd at at sik (RA) , we dɛn kin kɔl bak rεumatoid atraytis
2. Insay Ɔgan ɛn Stem Sɛl Transplant
Imajin se dɛn transplant sɔmbɔdi in ɔgan, lɛk in kidni, liva, ɔ at. di bכdi in imyun sistεm de si dis nyu כgan lεk "fכrin." So i tink se na fɔrina ɛn atak am, tray fɔ rijɛkt am (ɔgan rijɛkt). fכ mek dat nכ de, dat na fכ mek di bכdi aksept di nyu כgan, dεn de gi dis (Immunosuppressant) mεdisin.
Semweso, dɛn kin transplant stem sɛl fɔ blɔd kansa lɛk lukimiya ɛn talasemia. di imyun sistεm we de divεlכp frכm dεn nyu sεl dεm ya kin atak di ol bכdi. Dɛn kɔl dis (Graft-versus-host disease - GvHD) . Dis mɛrɛsin impɔtant bak fɔ mek yu nɔ gɛt dis sik.
Aw a go gɛt dis mɛrɛsin ɛn fɔ aw lɔng?
Dɛn kin tek dɛn mɛrɛsin ya as pils, wata, injɛkshɔn, ɔ insay di bɛlɛ (IV) . Dipen pan yu sik, yu kin nid fɔ tek dɛn mɛrɛsin ya fɔ sɔm mɔnt, wan ia, ɔr yu wan ol layf. Ɛspɛshali if dɛn dɔn transplant yu ɔgan, yu go nid fɔ kɔntinyu fɔ tek dɛn mɛrɛsin ya fɔ lɔng tɛm we yu dɔktɔ tɛl yu fɔ tek am.
Wetin na di kayn mɛrɛsin wae dɛn kin yuse pasmak?
Bɔku kayn mɛrɛsin ya de. Dipen pan yu sik, yu dɔktɔ go pik di mɛrɛsin ɔ di kɔmbayn mɛrɛsin we go fayn fɔ yu.
| Tayp fɔ mɛrɛsin | Wan simpul ɛksplen |
|---|---|
| Kɔtikosterɔyd dɛn Eks: Prɛdnisɔn | Dis na di kayn dɛn we dɛn kin yuz mɔ. Dɛn kin kɔntrol di we aw di imyun sistɛm de wok kwik kwik wan ɛn di inflamɛns. |
| Bayolojikal tin dɛn Eks: Adalimumab, Infliximab, we de na di bɔdi | dis dεm de prodyuz na di labכtכri εn dεn de tכk to spεsifi k pat dεm na di imyun sistεm. |
| Di tin dɛn we de stɔp di kalsinyurin Eks: Takrɔlimus, Sayklɔspɔrin | I de blok wan ɛnzaym we de mek di T-sɛl dɛn (wan kayn wayt blɔd sɛl) we de fɛt infɛkshɔn. |
| Ɔda difrɛn kayn dɛn (IMDH inhibito dεm, Janus kinase inhibito dεm, mTOR inhibito dεm) | dis dεm de kכntro tin dεm lεk di sεl dεm we de gro, di inflammatory enzymes, εn di sεl dεm we de proliferate. |
Wetin na di bɛnifit, di bad tin dɛn we kin apin to dɛn, ɛn di prɔblɛm dɛn we dɛn kin gɛt we dɛn de tek dɛn mɛrɛsin ya?
Pan ɔl we dɛn mɛrɛsin ya kin ɛp pɔsin fɔ sev in layf, dɛn kin mek sɔm bad bad tin dɛn ɛn sɔm prɔblɛm dɛn bak.
Sɔm sayd ɛfɛkt dɛn we pɔsin kin gɛt
Dɛn mɛrɛsin ya na rili strɔng mɛrɛsin ɛn dɛn kin mek difrɛn sayd ɛfɛkt dɛn. Nɔto ɔlman go ɛkspiriɛns ɔl dɛn tin ya.
- Akni we gɛt akni
- Risk fɔ gɛt dayabitis
- Di bɔdi taya pasmak
- Di ia we de lɔs ɔ we i nɔ want fɔ gro
- Ed de at
- Di ay blɔd prɛshɔn
- Sɔl dɛn na yu mɔt
- Ɔstioporosis we pɔsin kin gɛt
- Di we aw pɔsin kin shek shek
- We yu de gɛt mɔ wet
- Bɛlɛ de at, nɔs, ɛn vɔmit
If yu gɛt mɔ pan dɛn sayd ɛfɛkt ya pas aw yu kin gɛt, tɛl yu dɔktɔ wantɛm wantɛm. I kin ebul fɔ chenj di mɛrɛsin ɔ gi am difrɛn mɛrɛsin.
Speshal risk ɛn kɔmplikeshɔn dɛn
1. Fɔ skip fɔ tek mɛrɛsin
Dis na tin we rili siriɔs. Nɔ skip wan doz fɔ dis mɛrɛsin fɔ ɛni rizin ɔ if yu dɔktɔ nɔ gi yu advays. If pɔsin we gɛt ɔtoimyun sik du dis, di sik kin wɔs wantɛm wantɛm. If pɔsin we dɛn dɔn transplant in ɔgan stɔp fɔ tek di mɛrɛsin, di bɔdi go bigin fɔ rijek di ɔgan.
2. Di risk fɔ gɛt infɛkshɔn kin bɔku
As wi bin dɔn tɔk, dɛn mɛrɛsin ya kin mek di imyun sistɛm wik. Dis min se di tin dɛn we yu bɔdi kin ebul fɔ protɛkt kin ridyus. Dis kin mek yu (immunocompromised) , we min se yu imyuniti wik. Dis min se yu kin gɛt siriɔs infɛkshɔn izi wan pas nɔmal pɔsin. Ɛgzampul dɛn:
- Sepsis (infεkshɔn na di blɔd) .
- Fכngal infεkshכn dεm (e.g., thrush) .
- Infεkshכn dεm na di skin (Cellulitis) .
- Infεkshכn dεm we de na di rεspiretכri (e.g., kol, nyumonia) .
Wetin a go du fɔ mek a gɛt wɛlbɔdi we a de du tritmɛnt?
Insay dis tɛm we yu dɔn mek yu bɔdi nɔ gɛt bɛtɛ wɛlbɔdi bay wilful, yu nid fɔ tink bɔt yu sef pas ɛni ɔda tɛm.
- Was yu an ɔltɛm wit sop ɛn wata. Dis na di bɛst we fɔ mek yu nɔ gɛt di sik.
- Tɔk to yu dɔktɔ bɔt di vaysin dɛn. Aks am us vaysin yu fɔ gɛt ɛn yu nɔ fɔ gɛt.
- It tin dɛn we gɛt fayn fayn tin dɛn fɔ it. It fayn it wit vɛjitebul, frut, ɔl gren, ɛn prɔtin we dɛn kuk fayn fayn wan.
- Gɛt inof slip. Fɔ slip fayn de sɔpɔt di imyun sistɛm.
- Nɔ go na say dɛn we pipul dɛn kin ful-ɔp ɛn ples usay sik pipul dɛn de as mɔ as yu ebul.
Dɛn mɛrɛsin ya kin gɛt ɛni ɛfɛkt we uman gɛt bɛlɛ?
Yɛs, i rili ebul fɔ du am. Ɛnibɔdi we de tek dis mɛrɛsin ɛn plan fɔ bɔn pikin fɔ tɔk to in dɔktɔ bifo tɛm. Sɔm mɛrɛsin dɛn kin ambɔg di pikin we de na di bɛlɛ ɛn i kin mek dɛn bɔn pikin dɛn we nɔ fayn. Dɔn bak, sɔm mɛrɛsin dɛn nɔ fayn we dɛn de gi pikin in bɛlɛ. So, if yu dɔktɔ want, i kin chenj yu to mɛrɛsin we sef we fayn fɔ gɛt bɛlɛ.
Mɛsej we dɛn kin kɛr go na os
- Immunosuppressants na wan rili pawaful klas ɔf drɔgs we dɛn kin yuz fɔ siriɔs kɔndishɔn lɛk ɔtoimyun sik ɛn ɔgan transplant.
- Nɔ ɛva skip wan doz ɔ chenj di doz if yu dɔktɔ nɔ advays yu.
- Bikɔs di risk fɔ gɛt di sik kin bɔku we yu de tek dis mɛrɛsin, i rili impɔtant fɔ fala di tin dɛn we yu fɔ tek tɛm wit lɛk fɔ was yu an ɔltɛm ɛn fɔ de fa frɔm sik pipul dɛn.
- Tɛl yu dɔktɔ wantɛm wantɛm bɔt ɛni sayd ɛfɛkt ɔ sɔm kayn sayn we nɔ kɔmɔn we yu gɛt.
- If yu de op fɔ bɔn pikin, mek shɔ se yu go to yu dɔktɔ bifo yu plan fɔ gɛt bɛlɛ.
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