We yu ɔ sɔmbɔdi na yu famili bigin fɔ gɛt kansa tritmɛnt, i nɔmal fɔ mek yu fred smɔl ɛn want fɔ no bɔt di mɛrɛsin dɛn we yu dɔktɔ gi yu. I impɔtant fɔ no ɔltin we yu de bigin fɔ tek nyu mɛrɛsin. So tide wi go tɔk bɔt wan kayn spɛshal anti-kansa drɔg, Lorlatinib. Lɛ wi tɔk bɔt am simpul wan, lɛk se yu padi de ɛksplen am to yu.
Wetin na Lorlatinib?
Fɔ tɔk am simpul wan, lorlatinib nɔto wan tipik kemotɛrapi mɛrɛsin. I de wok lɛk "targeted therapy." Dis min se i de tɔch sɔm patikyula prɔtin dɛn we de ɛp di kansa sɛl dɛn fɔ gro dairekt wan. We i du dat, i kin mek di kansa sɛl dɛn nɔ gro.
Dɛn kin yuse am mɔ fɔ trit wan sik we dɛn kɔl "nɔ-smɔl sɛl lɔng kansa." Yu dɔktɔ kin gi yu dis mɛrɛsin bak fɔ ɔda sik dɛn. If yu gɛt ɛni kwɛstyɔn bɔt am, aks yu dɔktɔ.
Tin dɛm fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Bifo yu dɔktɔ gi yu dis mɛrɛsin, i impɔtant fɔ no gud gud wan bɔt ɛni ɔda mɛrɛsin we yu go gɛt. Dis mεdisin kin intarakt wit dεn kכndyushכn dεm. So, if yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɛl yu dɔktɔ.
- Dayabitis (we blɔd gɛt bɔku shuga) .
- Di ay blɔd prɛshɔn
- Kɔlestɔl we bɔku
- At ritm we nɔ de rit ɔltɛm ɔ at sik
- Kidni sik
- Lɔng sik ɔ lɔng skata
- Ɛni sik we pɔsin kin gɛt na in maynd
- Kɔndishɔn dɛn lɛk we pɔsin kin gɛt sik
- Tin fɔ tink bɔt fɔ du bad to yusɛf, fɔ tink bɔt fɔ kil yusɛf, fɔ tray fɔ du dat, ɔ fɔ mek yu fambul du dat
- Tray fɔ gɛt bɛlɛ ɔ fɔ gɛt bɛlɛ naw
- Fɔ gi di pikin in bɛlɛ
- Yu dɔn gɛt alɛji fɔ lorlatinib ɔ ɛni ɔda mɛrɛsin, it, ɔ day
Aw ɛksaktɔli yu kin yuz dis mɛrɛsin?
Fɔ fala di rayt instrɔkshɔn fɔ yuz dis mɛrɛsin rili impɔtant fɔ di rizɔlt.
- Tek dis pil jɔs lɛk aw yu dɔktɔ tɛl yu fɔ tek am, di sem tɛm ɛvride .
- Nɔ krɔs, krɔs, ɔ chew di tablɛt. Swɛla am ɔl wit wata.
- Yu kin tek am bifo ɔ afta yu it, bɔt if yu bɛlɛ at, i bɛtɛ fɔ tek am wit it.
- Kɔntinyu fɔ yuz dis tritmɛnt te yu dɔktɔ tɛl yu fɔ stɔp.
- I rili impɔtant:Nɔ drink grep jus ɔltogɛda we yu de tek dis mɛrɛsin.
Wetin fɔ du if di doz tu bɔku? (Ovados) .
If yu tink se yu dɔn tek bɔku mɛrɛsin, go na di Imejɛnsi Dipatmɛnt (ETU) we de nia yu wantɛm wantɛm . Ɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital fɔ advays.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu fɔgɛt fɔ tek wan doz, tek am jɔs lɛk aw yu mɛmba. Bɔt if i nɔ rich 4 awa te yu tek di nɛks doz, skip di doz we yu mis. Jɔs tek di nɛks doz na di tɛm we dɛn dɔn sɛtul. Nɔ ɛva tek dabl doz .
Ɔda mɛrɛsin dɛm wae kin miks wit dis mɛrɛsin
Lorlatinib na wan mɛrɛsin wae gɛt ay potenshal fɔ intarakshɔn wit ɔda mɛrɛsin dɛm. So, yu fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn, ɛbul mɛrɛsin, ɛn ɛbul ti). I kin intarakt wit dɛn mɛrɛsin ya:
| Nɔ ɛva tek dɛn tin ya wit lorlatinib. | |
|---|---|
| apalutamid, ɛnzalutamid, maytotan, ranolazin | Drɔg dɛm we dɛn kin gi fɔ difrɛn kansa ɛn at sik dɛm |
| Antiepileptic dεm lεk kabamazεpin, fεnitoin, fεnobarbital | Mɛrɛsin fɔ mek pɔsin gɛt sik we de mek pɔsin sik |
| rifampin, we dɛn kɔl rifapentin | Antibayɔtik fɔ baktriyal infɛkshɔn lɛk TB |
| Sɛnt Jɔn in Wɔt | Wan ɛbul sɔpɔt fɔ pwɛl hat |
| lumacaftor we dɛn kɔl lumacaftor; ivacaftor we dɛn kɔl ivacaftor | Mɛrɛsin fɔ Sistik Faybrosis |
| Yu kin riak wit dɛn tin ya - aks yu dɔktɔ. | |
| Antibayɔtiks | Eks: klaritromaysin |
| Antifungals dɛn we dɛn kin yuz | Eg: ketokonazol, itrakonazol, flukonazol |
| HIV ɛn ɛpatitis drɔgs | Eks: ritonavir, boseprɛvir |
| Ɔmon ɛn kɔntrol fɔ bɔn pikin | Tin dɛm lɛk bɔn kɔntrol pils, pat, injɛkshɔn, ɛn ɔda tin dɛm. |
| Ɔda mɛrɛsin dɛn | bosentan, modafinil, midazolam, we dɛn kɔl midazolam |
Tin dɛn we yu fɔ mɛmba we yu de tek mɛrɛsin
I nɔmal fɔ fil sɔm kayn prɔblɛm we yu de trit kansa, bikɔs i kin afɛkt ɔl tu di kansa sɛl dɛn ɛn di wɛlbɔdi sɛl dɛn. Bɔt nɔ stɔp di tritmɛnt te yu dɔktɔ tɛl yu fɔ du dat. Tɛl yu dɔktɔ bɔt ɛni bad bad tin we go apin to yu.
Bεlε, bεlε εn man advays
Dis pat rili impɔtant. Duya una pe atɛnshɔn gud wan.
- Fɔ uman dɛn: Nɔ gɛt bɛlɛ ɔltogɛda we yu de tek dis mɛrɛsin. Dɔn bak, nɔ fɔ gɛt bɛlɛ fɔ 6 mɔnt afta yu dɔn stɔp di mɛrɛsin. Yuz wan we we nɔ gɛt ɔmon fɔ kɔntrol di pikin (e.g., kɔndɔm, kɔpa T). Tɛl yu dɔktɔ wantɛm wantɛm if yu gɛt ɛnitin fɔ tink se yu gɛt bɛlɛ. Nɔ gi pikin bɔbi we yu de tek di mɛrɛsin ɛn fɔ 7 dez afta yu dɔn stɔp di mɛrɛsin.
- Fɔ man dɛn:Man dɛm we de tek dis mɛrɛsin fɔ yuz kɔndɔm we dɛn de du mami ɛn dadi biznɛs wit uman we kin gɛt bɛlɛ. Dis we fɔ mek uman nɔ gɛt bɛlɛ fɔ kɔntinyu fɔ 3 mɔnt afta dɛn dɔn stɔp di mɛrɛsin. If yu tink se yu patna gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm.
Infɛkshɔn ɛn fiva
Dis mɛrɛsin kin mek yu bɔdi nɔ ebul fɔ fɛt di sik ɛn i kin mek yu gɛt infɛkshɔn mɔ ɛn mɔ. So, if yu gɛt sɔm sayn dɛn lɛk fiva, kol, trot we de at, ɔ kɔf, nɔ fɔ tek mɛrɛsin fɔ yusɛf ɛn kɔl yu dɔktɔ wantɛm wantɛm fɔ advays. Tray fɔ de fa frɔm pipul dɛn we sik.
Di kɔlɔstrel ɛn di shuga lɛvɛl
Lorlatinib kin mek di blɔd kɔlɔstrel (especially triglycerides) ɛn di blɔd shuga lɛvɛl go ɔp. I kin mek bak di gud kɔlɔstrel (HDL) go dɔŋ. Yu dɔktɔ go de chɛk dɛn tin ya ɔltɛm. If nid de, dɛn kin tɛl yu fɔ chenj di it we yu de it ɔ fɔ tek nyu mɛrɛsin.
Di chenj dɛn we de apin na di maynd wɛlbɔdi
Dis mɛrɛsin kin afɛkt sɔm pipul dɛn na dɛn maynd. Tɛl yu dɔktɔ wantɛm wantɛm if yu ɔ yu fambul notis ɛni wan pan dɛn chenj ya:
- Nyu ɔr de wɔs pwɛl hat
- Tin dɛn fɔ tink bɔt fɔ du bad to yusɛf
- Wɔri
- Di mɛmori we yu nɔ ebul fɔ mɛmba
- Biɛvhɔ ɔ tinkin wae nɔr kɔmɔn, wae de mɔna yu
Us bad bad tin dɛn kin apin we pɔsin kin si?
Lɛk ɛni mɛrɛsin, lorlatinib kin gɛt sayd ɛfɛkt. Sɔm pan dɛn tin ya kin siriɔs ɛn dɛn fɔ ripɔt dɛn wantɛm wantɛm.
| Sayd ɛfɛkt dɛn we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
|---|---|
| Alɛji we pɔsin kin gɛt | Skin de rɔsh, it, swel na yu fes, lip, ɔ tong |
| Chɛst de pen ɔ tayt | I kin bi sayn dɛn we de sho se pɔsin gɛt at atak |
| Kɔf, i nɔ kin izi fɔ blo, di bɔdi kin swel (ɛdima) . | We yu gɛt bɔku bɔku wet wantɛm wantɛm, yu anklɛ, an ɛn fut kin swel |
| Di sayn dɛm we de sho se di liva dɔn pwɛl | Dak yɔlɔ ɔ brawn urine, yɔlɔ na di yay/skin, pen na di ɔp rayt say na di bɛlɛ |
| Sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol, trot we de at |
| Di sayn dɛn we de sho se di blɔd sɛl dɛn nɔ bɔku | I nɔ kin izi fɔ blo, i kin taya pasmak, i kin fɔdɔm, i kin gɛt layt |
| Mental chenj ɔr epilepsy | Di mental simptom dɛm wae de ɔp, kɔnfyushɔn, sik wae de mɛk pɔrsin fil fayn |
| Tɛl yu dɔktɔ if i kɔntinyu fɔ de ɔ i de mɔna yu. | |
| Nɔs, fɔ vɔmit | Blɔd prɛshɔn we de go ɔp |
| Vishɔn de chenj, blurred vishɔn | Di kɔlɔstrel lɛvɛl we de go ɔp |
| Nɔr kin slip ɔr nɔr kin slip fayn | Memori lɔs, we pɔsin kin vɛks |
Mɛsej we dɛn kin kɛr go na os
- Tek di mɛrɛsin jɔs lɛk aw yu dɔktɔ tɛl yu, di rayt tɛm, ɛn di rayt doz. Nɔ ɛva brok ɔ krɔs di pil.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn, vaytamɛn dɛn, ɛn ɛbul prɔdak dɛn we yu de tek. Ɛspɛshali nɔ drink grep jus.
- Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ lɔng tɛm we yu dɔktɔ tɛl yu. Uman ɛn man fɔ no bɔt dis.
- If yu gɛt ɛni siriɔs sayd ɛfɛkt lɛk fɔ mek yu nɔ ebul fɔ blo fayn, yu chɛst de pen, yu de swel bad bad wan, ɔ yu gɛt big chenj na yu maynd, go to dɔktɔ wantɛm wantɛm.
- Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ sheb am wit ɔda pipul dɛn fɔ ɛni rizin.
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