Wetin na Mɛtilin Blu? Lɛ wi lan mɔ bɔt dis drɔg.

Yu don eva hie di nem ‘Methylene Blue’? Sɔntɛm nɔto so. Na sɔm kayn drɔg we nɔ kin bɔku, bɔt we rili impɔtant. Na rili blu likwid. I tan lɛk day we yu put pan klos, bɔt i kin mɛn sɔm siriɔs sik dɛn. Okay, so mek wi si wetin di stori bi abaut dis strenj blu drog?

Wetin rili na Mɛtilin Blu?

Fɔ tɔk am simpul wan, mɛtilin blu na wan mɛrɛsin we dɔktɔ dɛn kin yuz fɔ mɛn wan sik we nɔ kin apin na di blɔd we dɛn kɔl methemoglobinemia . Pan ɔl we i rili sɔlid, we dɛn yuz am as drɔg, dɛn kin sɔlv am na wata ɛn gi am as injɛkshɔn as blu wata. Di istri bɔt dis drɔg bak rili intrestin. Na wan Jaman kemist bin fɛn am fɔ di fɔstɛm insay di ia 1900. Fɔs, dɛn bin de yuz am as day na di tin dɛn we dɛn de du fɔ mek klos. Leta, dɛn bin yuz am bak as pigmɛnt we dɛn bin de du ɛkspiriɛns dɛn na lɛbɔtri. Na lɛk 125 ia so dɔn pas we wan dɔktɔ na Jamani bin bigin fɔ yuz am fɔ mɛn malaria. Frɔm da tɛm de, di bɛnifit dɛn we i kin gɛt dɔn go bifo bad bad wan. Naw, na di US FDA nɔmɔ dɔn gri fɔ am as tritmɛnt fɔ mɛthemoglobinemia. Bɔt sɔntɛnde, dɔktɔ dɛn kin yuz am fɔ ɔda sik dɛn bak.

Us kayn sik dɛn kin yuz dis mɛrɛsin fɔ?

As wi bin dɔn tɔk, di men tin we dɛn kin yuz dis mɛrɛsin na fɔ mɛn wan sik we dɛn kɔl methemoglobinemia.

So wetin na mɛthemoglobinemia?

Dis na sik we gɛt fɔ du wit wi blɔd. Fɔ tɔk am simpul wan, we dis sik apin, di rɛd blɔd sɛl dɛn we de na wi blɔd nɔ kin ebul fɔ kɛr ɔksijɛn fayn fayn wan to di bɔdi in tisu dɛn. Sɔm pipul dɛn kin gɛt dis sik tru di jin, dat na frɔm dɛn mama ɛn papa. Bɔt fɔ bɔku pipul dɛn, i kin kam bikɔs dɛn de yuz sɔm mɛrɛsin dɛn, drɔgs, ɔ we dɛn de it sɔm kemikal dɛn . Methemoglobinemia na siriɔs sik we kin ivin mek pɔsin in layf de pan denja . Methylene blue na wan pan di bɛst tritmɛnt fɔ dis.

Aw dis mɛrɛsin de wok?

Methylene blu de wok bay we i de kεmikכl kכnvכlt di mεthemoglobin mכlikul dεm, we nכ kin kכri כksijεn, to εmoglobin mכlekyul dεm we kin kכri כksijεn. I tan lɛk se yu de chaj batri. Dɛn kin gi dis mɛrɛsin as IV na ɔspitul ɔ klinik bay dɔktɔ ɔ nɔs. I kin tek lɛk 5 to 30 minit so. Bɔrku tɛm, wan doz go ridyus di sayn dɛm. Bɔt if di sik stil de afta wan awa, di dɔktɔ kin disayd fɔ gi am ɔda doz.

Sayd ɛfɛkt ɛn intarakshɔn wit ɔda mɛrɛsin dɛn

Bifo yu gi yu dis mɛrɛsin, yu dɔktɔ go rivyu yu kɔmplit mɛdikal istri, bikɔs dis mɛrɛsin kin denja fɔ pipul dɛn we gɛt sɔm mɛrɛsin.

Wetin na di bad tin dɛn we kin apin to pɔsin?

Lɛk ɔl di mɛrɛsin dɛn, dis wan kin gɛt sayd ɛfɛkt.

• Smɔl smɔl sayd ɛfɛkt dɛn (nɔto natin fɔ wɔri bɔt):
• Blu-grin urine ɛn stɔl (dis na nɔmal tin, na di kɔlɔ we di mɛrɛsin gɛt) .
• Nɔs ɛn vɔmit
• Smɔl chenj na di skin kɔlɔ
• Pen na di an usay dɛn gi di IV

• Siriɔs sayd ɛfɛkt dɛn we dɛn fɔ ripɔt to di dɔktɔ wantɛm wantɛm:
• Chɛst de pen
• Diziz we pɔsin kin gɛt
• Ɛd we de at (ed we de at) .
• Kɔnfyus
• I de swet mɔ ɛn mɔ
• Bɛlɛ de at

Di intarakshɔn wit drɔgs

Dis na pat bak we rili impɔtant. Sɔm mɛrɛsin dɛn kin rili denja if dɛn tek am wit mɛtilin blu. Dis min se di kemikal we de na wi bren we de na wi bren kin bɔku pasmak, ɛn dis kin mek wi gɛt siriɔs sayn dɛn lɛk fɔ shek, fiva, wi nɔ kin no natin, ɛn ivin day. So, i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn, vaytamɛn dɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek.

Ɔda bɛnifit dɛn ɛn tin dɛn we gɛt fɔ du wit risach

Pan ɔl we na di FDA nɔmɔ gri fɔ mek dɛn gɛt mɛthemoglobinemia, dɔktɔ dɛn kin yuz am fɔ ɔda tin dɛn we gɛt fɔ du wit spɛshal kes dɛn. Dɛn kɔl dis ‘ɔf-lɛbul’ yus.

• As antidote: As antidote fɔ pɔyzin bay kemikal lɛk naytrayt, we dɛn kin yuz na sɔm faktri dɛm. If yu sɔspɛkt sɔntin lɛk dis, go na ɔspitul in Imejɛnsi Tritmɛnt Yunit (ETU) wantɛm wantɛm. If nid de, dɛn go kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital fɔ advays.
• Shok: Trit shɔk pan sɔm sik pipul dɛm we sik bad bad wan na di intensiv kia yunit (ICU).
• Fɔ no if pɔsin gɛt kansa: We dɛn de du ɔpreshɔn pan kansa, dɛn kin yuz am as day fɔ sho di kansa sɛl dɛn ɛn di limf no dɛn wit blu.
• Fɔ mek yu mɛmba fayn fayn wan: Dɛn de du risach fɔ si if dis kin fayn fɔ sik dɛm lɛk Alzaima wae kin kam wit yu ej.
• As disinfɛktant:Sɔm risach dɔn sho se if yu kam togɛda wit mɛtilin blu ɛn layt, i kin kil jem lɛk di korona vayrɔs.

Impɔtant: Bɔku pan dɛn tin ya stil de na di risach stej. So no jos trai dem out jos bikos yu si dem fo intanet. Ɔltɛm fala wetin yu dɔktɔ tɛl yu fɔ du. Methylene Blue, Methemoglobinemia, saynosis, G6PD dɛfisiɛns, Serotonin Sindrom, Mɛdikeshɔn sayd ɛfɛkt