Yu dɔktɔ dɔn gi yu wan kɔmbayn tu mɛrɛsin we dɛn kɔl Ribociclib ɛn Letrozole fɔ brɔst kansa? We yu si prɛskrishɔn lɛk dis, i kin mek yu fred smɔl ɛn i kin mek yu aks bɔku kwɛstyɔn. Bɔt nɔ wɔri. Dis na nɔmal tin. Lɛ wi tɔk simpul ɛn klia wan bɔt dɛn mɛrɛsin ya, aw dɛn kin afɛkt di bɔdi, aw fɔ yuz dɛn kɔrɛkt wan, ɛn wetin fɔ tek tɛm wit.
Wetin na Ribociclib ɛn Letrozole?
Fɔ tɔk am simpul wan, dis na tu kayn mɛrɛsin dɛn we dɛn kin gi fɔ kɔntrol aw di bɔdi kansa sɛl dɛn de gro. We dɛn gi dɛn tin ya togɛda, wi kin kɔl dɛn kɔ-pak.
- Ribociclib: Dis drɔg de wok bay we i de tɔch sɔm prɔtin dɛn we de insay di kansa sɛl dɛn we de ɛp dɛn fɔ sheb ɛn gro, ɛn stɔp dɛn fɔ wok. I de mek di kansa sɛl dɛn nɔ gro kwik kwik wan.
- Letrozole: Dis mεdikal de wok bay we i de blok di bכdi fכ mek wan כmon we dεn kכl εstrojen. Sɔm kayn bɔdi kansa kin yuz ɛstrojen as fiul fɔ mek i gro. So Letrozole de kɔt da fiul saplai de.
Dɛn tu mɛrɛsin ya kin wok togɛda fɔ atak di kansa sɛl dɛn frɔm tu say ɛn ɛp fɔ kɔntrol dɛn growth.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Bifo yu bigin dis tritmɛnt, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt yu kɔmplit wɛlbɔdi istri. Mek shɔ se yu tɛl am if yu gɛt ɛni wan pan dɛn tin ya:
| Di wɛlbɔdi stetmɛnt | Tɔk bɔt |
|---|---|
| At sik | If yu gɛt histri bɔt ɛni kayn at sik ɔ yu at nɔ de bit ɔltɛm. |
| Sik dɛn we kin apin na di liva | Ɛni liva sik we bin dɔn de bifo ɔ we de naw. |
| Di tin dɛn we de insay di blɔd we dɔn go dɔŋ | If dɛn bin dɔn no se yu gɛt smɔl wayt blɔd sɛl, rɛd blɔd sɛl, ɔ pletlɛt. |
| Minral imbalans dɛn | If yu nɔ gɛt bɔku kalsiɔm, magnɛsiɔm, potashɔm, ɔ fɔsfɔr na yu blɔd. |
| Infεkshכn dεm | Ɛni infɛkshɔn we de naw, mɔ di vayral infɛkshɔn lɛk chikinpoks ɔ hεpi. |
| Sik dɛn we kin kam na di lɔng | Lung ɔr respiratory sik dɛm lɛk asma. |
| Ɔda pɔynt dɛn | Tɛl bak bɔt di bon dɛn we wik, alɛji to ɔda mɛrɛsin, it, ɔ tin dɛn. |
| Bɛlɛ/we yu de gi pikin in bɛlɛ | If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ, i absolutely a must. |
Aw ɛksaktɔli a kin yuz dis mɛrɛsin?
Fɔ mek yu gɛt di bɛst pan yu mɛrɛsin, i rili impɔtant fɔ yuz am kɔrɛkt wan.
- Swɛla dɛn tablɛt ya wit wan glas wata. Nɔ krɔs ɔ chew di tablɛt dɛn.
- Tek yu mɛrɛsin jɔs lɛk aw yu dɔktɔ tɛl yu, di tɛm we dɛn tɛl yu. Nɔ skip di dos dɛn.
- Yu kin tek dis mɛrɛsin bifo ɔ afta yu it. Bɔt if yu bɛlɛ at, i go fayn fɔ tek am wit it.
- Impɔtant: Nɔ it grep, pomegranate, ɔ dɛn jus we yu de tek dis mɛrɛsin. Dɛn tin ya kin afɛkt di we aw di mɛrɛsin de wok fayn.
- Nɔ stɔp fɔ tek di mɛrɛsin if yu dɔktɔ nɔ advays yu.
If yu tink se yu dɔn tek bɔku mɛrɛsin, go na ɔspitul in Imejɛnsi Tritmɛnt Yunit (ETU) wantɛm wantɛm. Ɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital fɔ advays.
Wetin fɔ du if yu mis wan doz ɔ yu vɔmit?
If yu mis wan doz, ɔ if yu vɔmit afta yu tek di mɛrɛsin, nɔ tek ɔda pil da de de . Skip di doz we yu mis ɔltogɛda ɛn tek yu mɛrɛsin na yu rɛgyula tɛm di nɛks de. Nɔ tek tu dos wan tɛm.
Ɔda mɛrɛsin dɛn we yu nɔ fɔ yuz wit dis mɛrɛsin
Dis mɛrɛsin kin miks wit sɔm ɔda mɛrɛsin dɛn. So, i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn ɛn ɛbul mɛrɛsin dɛn) . Na mɔtalman, yu fɔ avɔyd fɔ tek dɛn mɛrɛsin ya wit dis mɛrɛsin. Dis list nɔ go kɔmplit, so tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
- Sɔm mɛrɛsin dɛn we dɛn kin tek fɔ at sik, kɔlɔstrel, fɔŋs infɛkshɔn, ɛn HIV/Epataytis.
- Sɔm mɛrɛsin dɛm wae dɛn kin yuse fɔ sik wae de mɛk yu sik (lɛk carbamazepine, phenytoin).
- Herbal prodakt dɛn lɛk `St. Jɔn in Wɔt`.
- Antibayɔtiks lɛk `kɛtokonazɔl` ɛn `klarithromycin`.
- כda mεdikeshכn dεm we de afekt di ilektrikal aktiviti na di at (QT intaval prolongation).
Wetin na di tin dɛn we yu fɔ tink bɔt we yu de tek di mɛrɛsin?
I rili impɔtant: Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 3 wik afta yu dɔn stɔp di mɛrɛsin. I kin mek bad bad tin apin to di pikin we de na in bɛlɛ. Dɔn bak, nɔ fɔ gi pikin in bɛlɛ dis tɛm. Fɔ man, dis mɛrɛsin kin afɛkt di sperm kɔnt bak, so tɔk to yu dɔktɔ if yu de tink bɔt fɔ bɔn pikin.
- Protɛkt yusɛf frɔm infɛkshɔn: Dis mɛrɛsin kin mek yu bɔdi nɔ ebul fɔ fɛt di sik smɔl. So una de fa frɔm pipul dɛn we sik. If yu gɛt sɔm kayn sik lɛk fiva, kol, ɔr yu trot we de at, nɔr de mɛn yusɛf ɛn tɛl yu dɔktɔ wantɛm wantɛm.
- Blɔd ɛn brus: I kin mek yu gɛt smɔl smɔl brus ɛn blɔd. Tek tɛm we yu de brus yu tit ɛn du yu tit fayn fayn wan. Tɛl yu dɔktɔ if yu notis ɛni blɔd ɔ brus we nɔ kɔmɔn.
- Di tin dɛn we de mek pɔsin fil pen: Nɔ tek tin dɛn we de mek pɔsin fil pen lɛk aspirin ɛn ibuprofen we yu nɔ gɛt yu dɔktɔ in advays. Dɛn tin ya kin stɔp di sayn dɛm lɛk fiva.
- Blɔd tɛst: Yu dɔktɔ go du blɔd tɛst ɔltɛm fɔ wach aw yu blɔd de bɔku ɛn aw yu liva de wok we yu de trit yu. Nɔ skip dɛn.
Yu fɔ no bɔt di bad tin dɛn we kin apin to yu
Lɛk ɛni mɛrɛsin, dis kin mek pɔsin gɛt sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn. Bɔt i impɔtant fɔ no bɔt dɛn.
| Di sayn dɛm wae yu fɔ ripɔt to yu dɔktɔ kwik kwik wan | |
|---|---|
| Di kwaliti we pɔsin gɛt | Tɔk bɔt |
| Alɛji dɛn we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip ɔ tong. |
| Di sayn dɛm we de sho se di liva dɔn pwɛl | Dak yɔlɔ/brawn urine, yu yay ɔ skin de yɔlɔ, pen na di ɔp rayt pat na di bɛlɛ, nɔs. |
| Sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol, trot we de at, kɔf, urinary tract infection. |
| Di chenj dɛn we de apin na di at rit | Chɛst pen, diziz, fil lɛk yu at de bit fast ɔr nɔr de bit ɔltɛm, i nɔ izi fɔ blo. |
| Di sayn dɛn we de sho se blɔd de klɔt | Wantɛm we yu nɔ de blo kwik, yu chɛst de pen, yu de swel ɛn pen na yu leg, i nɔ izi fɔ tɔk. |
| Di sayn dɛn we de sho se pɔsin nɔ gɛt bɛtɛ blɔd | Taya we nɔ kɔmɔn, paleness, izi fɔ brus, rɛd spat na di skin, blɔd na di urine. |
| Di sayn dɛm fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Dijestiv sistɛm | Kɔnstipɛshɔn, dayarɛa, nɔs/vɔmit, bɛlɛ pen, mɔt sɔri, nɔr kin want fɔ it. |
| Jɛnɛral kwaliti dɛn | Ɛd we de at, yu ia we de lɔs, wik, yu de swet na nɛt, yu nɔ de slip, yu an ɛn fut dɛn de swel. |
Aw yu kin protɛkt yu mɛrɛsin?
- Kip am usay pikin dɛn nɔ go ebul fɔ rich.
- Stɔr di mɛrɛsin insay di ɔrijinal pak na rum tɛmpracha bitwin 20-25 digri sɛlshiɔs.
- Trowe di mɛrɛsin we dɔn pas.
Dis infɔmeshɔn pepa na jɔs sɔmari. If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis mɛrɛsin, duya nɔ fred fɔ tɔk to yu dɔktɔ.
Mɛsej we dɛn kin kɛr go na os
- Tek yu mɛrɛsin jɔs lɛk aw yu dɔktɔ tɛl yu, di rayt tɛm. Nɔ skip di dos dɛn.
- Nɔ gɛt bɛlɛ ɔltogɛda insay dis tritmɛnt ɛn fɔ 3 wik afta yu dɔn stɔp am.
- Yu fɔ wach fɔ sayn dɛn we de sho se yu gɛt di sik, lɛk fiva ɛn trot we de at. If yu notis ɛnitin lɛk dis, tɛl yu dɔktɔ wantɛm wantɛm.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn, vaytamɛn dɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek.
- Nɔ drink grep ɛn granat ɔ dɛn jus.
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Wetin dɛn de yuz Ribociclib ɛn Letrozole / Kisqali Femara Kɔ-Pak fɔ?
Dis na kɔmbaynshɔn fɔ 2 ayli saksesful targeted therapy drugs we de kɔntrol ‘Advanced/Metastatic Breast Cancer’ kɔmplit wan pan uman dɛm! spεshal wan, dεn mek dis fכ pul di rut dεm fכ kεnsar dεm we de yuz di uman כmon ‘εstrojen’ (ER-positiv / HER2-negative) fכ gro.
💬 Aw dɛn tu mɛrɛsin ya (Ribociclib + Letrozole) kin kil bɔdi kansa?
Dis kin atak kansa frɔm ɔl tu di say dɛn! fכs, ‘Letrozole’ de blok di prodakshכn fכ di ‘estrogen hormone’ we de fכd/grכw kεnsar 100%, we de mek di kεnsar angri. afta dat, ‘Ribociclib’ de pwɛl tu εnzym mashin dεm (CDK4 εn CDK6) kכmplit wan we de εp di kεnsar sεl dεm fכ sheb kwik kwik wan εn gro. Dɔn, dɛn kin stɔp di kansa fɔ gro rayt de.
💬 Wetin na di men sayd effekt wae yu tek dis pawaful kansa drog?
we dεn de kil di kεnsar sεl dεm, di bכdi in ‘wayt bכdi sεl dεm/nyutrofil dεm (Neutropenia)' εn di rεd bכdi sεl dεm (mכr pas aw i bin de) dεn de dכn bak. So, ivin smɔl kol kin strɔng fɔ mek yu gɛt nyumonia ɛn day! Dɔn bak, bikɔs dɛn pils ya gɛt bɔku chans fɔ pwɛl di ‘Liva’ (Hepatotoxicity), dɔktɔ dɛn kin du blɔd tɛst (LFT) ɔltɛm. i kin chenj di hat rεt bak (QT prolongation).
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