Waliwo omuntu yenna mu maka go alina "Obulwadde bwa Sickle Cell"? Ka tukizuule mu bukakafu!

Leero tugenda kwogera ku mbeera empya katono eri abantu abasinga obungi, naye nga esobola okubeera ku lusegere ennyo n’amaka agamu. Buyitibwa obulwadde bwa Sickle Cell Disease (SCD). Oyinza okuba nga wali owuliddeko erinnya lino. Mu butuufu bulwadde obukwatagana n’omusaayi gwaffe, kwe kugamba, obukwatagana n’omusaayi, era nga busikira. Ka tulabe kiki ddala kye kiri, lwaki kibaawo, n’ebirala ebiyinza okukolebwa ku nsonga eyo.

Obulwadde bwa Sickle Cell kye ki? Ka tukitegeere mu ngeri ennyangu!

Mu ngeri ennyangu, obulwadde bwa sickle cell disease (SCD) bulwadde obukwata obutoffaali obumyufu mu mubiri gwaffe, obusikira abazadde okutuuka ku baana. Eno y’emu ku ndwadde z’omusaayi ezisikira mu nsi yonna. Kati laba, munda mu butoffaali bwaffe obumyufu mulimu puloteyina eyitibwa hemoglobin . Hemoglobin eno nkulu nnyo. Kubanga, ye puloteyina eno etambuza omukka gwa oxygen mu mubiri gwaffe gwonna. Kiringa takisi ya oxygen. Obutoffaali obumyufu obw’omuntu omulamu butera okuba obwetooloovu era nga bugonvu. Nga obupiira obutono obwa kapiira. Olw’ensonga eno, zisobola bulungi okwekulukuunya mu misuwa emitono ennyo mu mubiri (tugiyita emisuwa) ne ziwa omukka gwa oxygen eri ebitundu byaffe byonna n’ebitundu by’omubiri. Kyokka ekituuka ku muntu alina obulwadde bwa sickle cell kwe kuba nti waliwo enkyukakyuka entonotono mu hemoglobin eno. Hemoglobin eno etali ya bulijjo eyitibwa hemoglobin S. Kino kireetera obutoffaali obumyufu okufuuka obw’enkula y’omwezi, oba ekitundu ky’omwezi, mu kifo ky’okufuuka ekyekulungirivu era ekigonvu. Tekikoma awo, naye obutoffaali buno bukaluba nnyo, tebufukamira mangu era bunywerera wamu. Teebereza, kiki ekibaawo ng’obutoffaali buno obufaanana ng’akawundo butambula mu misuwa egyo emitonotono? Basibira mu kkubo! Olwo omusaayi ne gutaataaganyizibwa. Ekyo kitegeeza nti, ebitundu byaffe ebisinga obukulu n’ebitundu by’omubiri tebifuna mukka gwa oxygen gumala. Eno y’ensonga lwaki ebizibu eby’amaanyi ng’obulumi obw’amaanyi, yinfekisoni ez’enjawulo, okwonooneka kw’ebitundu by’omubiri, n’obutakola bulungi bisobola okubaawo. Ekirala obutoffaali buno obulinga ekiwujjo tebuwangaala nnyo ng’obutoffaali obumyufu obwa bulijjo. Bafa mangu. Olwo omubiri bulijjo guba n’ebbula ly’obutoffaali obumyufu. Kino kye tuyita okukendeera kw'omusaayi . Obulwadde bwa sickle cell mbeera eriwo obulamu bwonna. Naye teweeraliikiriranga, waliwo obujjanjabi ku kino. Bw’okozesa obujjanjabi buno, osobola okukendeeza ku bubonero n’okwongera ku bulamu bwo.

Waliwo ebika by’obulwadde bwa sickle cell eby’enjawulo?

Yee, waliwo ebika by’obulwadde bwa sickle cell ebiwerako. Ebika bino bisalibwawo obuzaale omuntu bw’asikira okuva mu bazadde be.

Ekirungo kya Hemoglobin SS (HbSS) .

Eno y’engeri y’obulwadde bwa sickle cell esinga okuba obw’amaanyi . Abantu nga 65% abalina SCD balina ekika kino. Abantu bano basikira obuzaale bwa hemoglobin S okuva mu bazadde bombi. Kino kitegeeza nti hemoglobin yaabwe esinga obungi oba yonna si ya bulijjo. Kino kibaleetera okufuna obulwadde bw’okubulwa omusaayi obutawona.

Ekirungo kya Hemoglobin SC (HbSC) .

Kino tekiba kya maanyi oba kya kigero.Ekika ekiri ku ddaala erya waggulu. Abantu nga 25% abalina SCD balina kino. Abantu bano basikira obuzaale bwa hemoglobin S okuva mu muzadde omu ate obuzaale bw’ekika kya hemoglobin ekirala ekitali kya bulijjo ekiyitibwa hemoglobin C okuva ku muzadde omulala.

Hemoglobin (HbS) Obulwadde bwa Beta Thalassemia

Abantu bano basikira obuzaale bwa hemoglobin S okuva ku muzadde omu ate obuzaale obutali bwa bulijjo obuyitibwa beta thalassemia okuva ku muzadde omulala. Waliwo n’ebika bibiri ebitonotono ebya kino:

• “Plus” (HbS beta +): Kino kika ekikwata abantu nga 8% abalina SCD era nga kitera okuba ekitono.
• “Zero” (HbS beta 0): Kino kika ekikwata abantu nga 2% abalina SCD era kiyinza okuba eky’amaanyi ng’obulwadde bwa hemoglobin SS (HbSS).

Ebika ebirala ebitali bimu

Ng’oggyeeko kino, waliwo ebika ebirala ebitali bimu nga hemoglobin SD (HbSD), hemoglobin SE (HbSE), ne hemoglobin SO (HbSO) . Abantu bano basikira obuzaale obumu obwa hemoglobin S n’obuzaale obulala obutali bwa bulijjo obuyitibwa D, E oba O.

Njawulo ki eriwo wakati w’obulwadde bwa Sickle Cell Anemia n’obulwadde bwa Sickle Cell?

Wano abantu bangi we batabulira. Obulwadde bwa Sickle Cell Disease (SCD) kigambo kya bulijjo ekitegeeza ebika byonna eby’enjawulo eby’obulwadde bwa sickle cell ebyogeddwako waggulu. Kiringa amaliba. Ebika ebirala byonna bigwa wansi w’amaliba ago. Abasawo bakozesa ekigambo "Sickle Cell Anemia" byokka ku bika bya SCD ebisinga okuba eby'amaanyi ebivaako okukendeera kw'omusaayi . Kwe kugamba, ebika ebiyitibwa hemoglobin SS (HbSS) ne hemoglobin beta zero thalassemia. Okukifuna?

Njawulo ki eriwo wakati w’Engeri ya Sickle Cell n’Obulwadde?

Abantu abamu balina engeri ya sickle cell yokka . Kino kitegeeza nti basikira obuzaale bwa hemoglobin S okuva ku muzadde omu yekka . Omuzadde omulala asikira obuzaale obulungi. Ebiseera ebisinga, abantu abalina engeri ya sickle cell tebalaga bubonero bwa bulwadde bwa sickle cell. Kyokka, basobola okuyisa obuzaale buno obutali bwa bulijjo mu baana baabwe. Kino kitegeeza nti be basitula obuzaale buno. Kyokka, si bulijjo nnyo, n’abantu abalina engeri y’obutoffaali obuyitibwa sickle cell bayinza okufuna obuzibu mu bulamu singa baggwaamu amazzi amangi oba singa bakola dduyiro ow’amaanyi . Okunoonyereza kukyagenda mu maaso ku nsonga eno.

Obulwadde bwa sickle cell butera kwenkana wa?

Abanoonyereza bateebereza nti abantu nga 100,000 mu Amerika yokka balina obulwadde bwa sickle cell. Businga kubeera mu bantu abava mu Afirika. Era kisangibwa mu Bannameriika aba Hispanic, n’abantu abava mu Mediterranean, Middle Eastern, Indian, ne Asian. Waliwo n’abantu abalina embeera eno mu Sri Lanka.

Kiki ekivaako obulwadde bwa sickle cell?

Obulwadde bwa sickle cell buva ku nkyukakyuka mu buzaale mu buzaale obuyitibwa HBB gene . Ensengekera eno eya HBB evunaanyizibwa ku kukola ekitundu kimu ekya hemoglobin. Abantu abalina SCD basikira obuzaale bwa HBB bubiri obukyusiddwa obukola hemoglobin etali ya bulijjo – emu okuva mu buli muzadde. Kino kiyitibwa obusika obuyitibwa autosomal recessive inheritance. Kino kitegeeza nti abazadde bombi ab’omwana alina SCD batambuza kkopi emu ey’obuzaale obukyusiddwa (ekitegeeza nti basobola okuba n’engeri ya sickle cell). Kyokka abazadde abo ebiseera ebisinga tebalaga bubonero.

Ani ali mu bulabe obw’okulwala obulwadde bwa sickle cell disease (SCD)?

Ebibinja by’abantu ebimu bitera okulwala obulwadde buno. Bbo bali:

• Abantu abava mu Afirika (e.g. Abafirika Abamerika).
• Abamerika aba Hispanic mu South America ne Central America.
• Abantu abava mu Mediterranean, Middle East, Buyindi, ne Asia.

Bubonero ki obulaga obulwadde bwa sickle cell?

Obubonero bw’obulwadde bwa sickle cell butera okutandika okulabika ng’omwana alina emyezi nga 5 ku 6 . Obubonero buno busobola okwawukana okusinziira ku muntu. Abantu abamu baba n’obubonero obutono, ate abalala basobola okufuna ebizibu eby’amaanyi. Obubonero obukulu obuyinza okulabibwa bwe buno:

• Ebiseera by’obulumi ebitera okubaawo.
• Okukendeera kw’omusaayi : Kino kiyinza okuvaako okukoowa ennyo, okufuuka omumyufu, n’okunafuwa.
• Jaundice : Olususu okufuuka olwa kyenvu n’amaaso okweru.
• Okuzimba emikono n’ebigere nga biruma.

Bizibu ki ebiva mu mbeera eno?

Obulwadde bwa sickle cell busobola okukwata ebitundu by’omubiri bingi. Ebikosa ebimu bitandika mangu (acute), ate ebirala biwangaala (chronic). Ebizibu bino bisobola okutandika nga bukyali ne bimala obulamu bwonna.

Obulumi

Kino kye kizibu ekisinga okuva mu bulwadde bwa sickle cell. Obulumi buno bubaawo ng’obutoffaali obulinga ekikonde busibira mu misuwa ne buziyiza omusaayi okutambula. Oyinza okufuna obulumi obw’amangu era obw’amaanyi. Kino era kiyitibwa obuzibu bw’obulumi, obuzibu bw’obutoffaali obuyitibwa sickle cell, obuzibu bw’okuzibikira emisuwa (VOC), oba ekitundu ekiziyiza emisuwa (VOE) . Ebizibu bino eby‟obulumi biyinza okuba ebitono oba eby‟amaanyi, era bisobola okutandika amangu ddala ne bimala ebbanga lyonna. Obulumi businga kubeera mu kifuba, omugongo, amagulu n’emikono. Abantu abamu bayinza okuba n’obulumi obutawona , ekitegeeza obulumi obumala emyezi egisukka mu mukaaga.

Okukendeera kw’omusaayi

Obulwadde bwa sickle cell buleeta okukendeera kw’omusaayi kubanga obutoffaali obumyufu bufa mangu. Okukendeera kw’omusaayi kwe kubulwa obutoffaali obumyufu obulungi obuyinza okutambuza omukka gwa oxygen mu mubiri gwonna. Eno y’ensonga lwakiOkukoowa ennyo, jaundice, obutawummulamu, okuziyira n’okuziyira biyinza okubaawo.

Obulwadde bw’ekifuba obuyitibwa Acute Chest Syndrome

Eno mbeera ya mangu ey’obujjanjabi eyinza okutta omuntu . Kiyinza okwonoona amawuggwe, okukaluubirirwa okussa, n’okukendeeza ku mukka gwa oxygen mu bitundu by’omubiri ebirala. Obuzibu buno bubaawo ng’obutoffaali obuyitibwa sickle cells buziyiza omusaayi ne oxygen okugenda mu mawuggwe.

Okuzimba Omusaayi

Sickle cell anemia eyongera obulabe bw’omusaayi okuzimba. Kino kyongera obulabe bw’okukula kw’omusaayi mu musuwa omuzito (deep vein thrombosis - DVT). DVT nayo esobola okukutuka n’esigala mu mawuggwe (pulmonary embolism - PE).

Storoko

Singa obutoffaali obuyitibwa sickle cells busibira mu musuwa ogugenda mu bwongo, omusaayi ogugenda mu bwongo guzibikira. Obwongo tebufuna mukka gwa oxygen gumala okukola. Kino kiyinza okuvaako okusannyalala . Abantu nga 10% abalina SCD bajja kuba n’obulwadde bwa stroke obw’obujjanjabi. Abantu abalina obulwadde bwa sickle cell anemia bali mu bulabe bwa maanyi okukwatibwa obulwadde bwa stroke.

Ebizibu by’okulaba

Obutoffaali obuyitibwa sickle cells busobola okuziba emisuwa mu maaso. Kino kisinga kubeera mu kitundu ky'amaaso ekiyitibwa retina . Oluusi tewabaawo bubonero ate oluvannyuma okulaba kuyinza okubula mu bwangu, era kiyinza n’okuziba amaaso ag’olubeerera.

Enkola ya Priapism

Priapism mbeera obutoffaali obulinga ekiso mu busajja bw’omusajja mwe buzibikira, ekivaako okusituka okutambula obutasalako, okuluma ( priapism ). Ng’oggyeeko obulumi, priapism esobola okuleeta okwonooneka okw’olubeerera n’okulemererwa okusituka . Obulwadde bwa Priapism obumala essaawa ezisukka mu nnya buba bwa mangu mu by’obujjanjabi.

Okwonooneka kw’ebitundu by’omubiri n’okulemererwa

Abantu abalina obulwadde bwa sickle cell bali mu bulabe bw’okufuna obuzibu ku mutima, amawuggwe, ensigo, n’ebitundu by’omubiri ebirala kubanga tebafuna musaayi na oxygen bimala. SCD eyinza okuvaako ebitundu by’omubiri ebingi okulemererwa .

Engeri oba obulwadde bwa sickle cell bukosa olubuto?

Abakyala bangi abalina obulwadde bwa sickle cell baba n’embuto ennungi. Naye akabi akaliwo kali waggulu. SCD esobola okwongera ku bulabe bwa puleesa, okuzimba omusaayi, okuvaamu embuto, abaana abazaalibwa nga bazitowa nnyo, n’okuzaala nga tebanneetuuka . N’olwekyo kikulu okugoberera amagezi g’omusawo wo.

Obulwadde bwa sickle cell buzuulibwa butya?

Mu Sri Lanka, nga bwe kiri mu nsi nnyingi okwetoloola ensi yonna, buli mwana eyaakazaalibwa akeberebwa obulwadde bwa sickle cell ng’ekimu ku bigenda okukeberebwa abalongo . Kino kizingiramu okuggya omusaayi omutono mu kisinziiro ky’omwana n’okugukebera. Kino era kikebera endwadde endala eziwerako. Okukakasa nti omwana azuuliddwa, omusawo w’omwana ajja kukola ekigezo kya hemoglobin electrophoresis . Ate era, obulwadde bwa sickle cell busobola okuzuulibwa nga omwana tannazaalibwa nga bayita mu kukeberebwa nga tannazaalibwa . Ebigezo bino mulimu:Mu bino mulimu okutwala sampuli za chorionic villus ne amniocentesis .

Waliwo eddagala erijjuvu eriwonya obulwadde bwa sickle cell?

Yee, okusimbuliza obusigo bw’amagumba , era ekimanyiddwa nga okusimbuliza obutoffaali obusibuka, kusobola okuwonya obulwadde bwa sickle cell. Kino kizingiramu okuggya obusigo bw’amagumba obulungi okuva ku muntu omulamu obulungi, akwatagana n’obuzaale (nga muganda we) n’okubusimbuliza mu mulwadde. Wabula abantu nga 18% bokka abalina SCD be basobola okufuna omukwano ng’ogwo. Waliwo n’obulabe n’ebizibu ebiva mu kusimbuliza kuno. Omusawo wo ajja kuteesa naawe ku nsonga eno.

Bujjanjabi ki obw’obulwadde bwa sickle cell?

Obujjanjabi bw’obulwadde bwa sickle cell buzingiramu eddagala, okuteekebwamu omusaayi, okusimbuliza obusigo bw’amagumba, n’okujjanjaba obuzaale . Obujjanjabi buyinza okutandika n'eddagala eritta obuwuka . Abalongo abalina SCD ey’amaanyi baweebwa eddagala eritta obuwuka emirundi ebiri olunaku okumala emyaka 5 okuziyiza okukwatibwa obulwadde.

Eddagala eddala

Abantu bangi abalina SCD bakozesa eddagala okukendeeza ku buzibu bw’obulwadde bwabwe n’okujjanjaba obubonero. Ebimu ku bino mulimu:

• Voxelotor: Kino kiyinza okutangira obutoffaali obumyufu obutafuuka bwa sickle ne bukwatagana. Kino kiyinza okukendeeza ku kusaanyaawo obutoffaali obumu obumyufu, omusaayi okutambula obulungi mu bitundu by’omubiri, n’okukendeeza ku bulabe bw’okubulwa omusaayi.
• Crizanlizumab: Eddagala lino liyamba okuziyiza obutoffaali obumyufu obulinga sickle okunywerera ku bisenge by’emisuwa . Kino kiyinza okulongoosa entambula y’omusaayi n’okukendeeza ku buzimba n’obulumi.
• Hydroxyurea : Kino kiyinza okukendeeza oba okuziyiza ebizibu ebiwerako ebya SCD, gamba ng’okulumwa ennyo, obulwadde bw’ekifuba obw’amaanyi, n’okubulwa omusaayi ennyo.
• L-glutamine: Kino kikendeeza ku bulumi. Kiyinza okuyamba okukendeeza ku muwendo gw’obulumi bw’olina. Eddagala eddala eriweweeza ku bulumi mulimu eddagala eriziyiza okuzimba eritali lya steroid (NSAIDs) n’eddagala eriweweeza ku bulumi .

Okuteekebwamu omusaayi

Omusawo ayinza okukuwa amagezi okuteekebwamu omusaayi ogumu okujjanjaba n’okuziyiza ebizibu ebiva mu SCD.

• Okuteekebwamu omusaayi mu ngeri ey’amangu:Bino biyamba okujjanjaba ebizibu ebivaako okukendeera kw’omusaayi okw’amaanyi. Abasawo basobola n’okuzikozesa ku bizibu nga stroke, acute chest syndrome, n’okulemererwa kw’ebitundu by’omubiri.
• Okuteekebwamu obutoffaali obumyufu: Bino bisobola okwongera ku butoffaali obumyufu mu mubiri n’okuwa obutoffaali obumyufu obwa bulijjo obutali mu ngeri ya sickle.

Okusimbuliza obutoffaali obusibuka (ekiyitibwa okukyusa obusigo bw’amagumba) .

SCD esobola okuwona n’okusimbuliza obutoffaali obusibuka mu mubiri. Kino kyetaagisa omugabi akwatagana obulungi (nga muganda we). Okunoonyereza era kugenda mu maaso okusobola okulongoosa enkola y’okusimbuliza okuva mu bazadde oba baganda baabwe abakwatagana ekitundu. Omusawo wo ajja kwogera ku bulabe n’emigaso gy’obujjanjabi buno okusinziira ku mbeera gy’olimu entongole.

Obujjanjabi bw’obuzaale

Mu kiseera kino abanoonyereza bali mu kunoonyereza ku bujjanjabi bw’obuzaale okujjanjaba SCD. Kino kizingiramu okutereeza obuzaale bwa hemoglobin obutali bwa bulijjo oba okuyingiza obuzaale bwa hemoglobin obulungi mu butoffaali bw’omuntu. Data eyasooka ku kino esuubiza nnyo. Essuubi liri nti obujjanjabi bw’obuzaale olunaku lumu bujja kufuuka obujjanjabi obwa bulijjo eri SCD.

Kino kisobola okuziyizibwa?

Obulwadde bwa sickle cell mbeera ya buzaale, n’olwekyo tebusobola kuziyizibwa . Bw’oba ​​oli lubuto, kirungi okwogera n’omusawo wo ku kukebera obuzaale oba okubudaabudibwa ku buzaale . Kino kijja kukuyamba ggwe ne munno okumanya oba olina obuzaale n’akabi k’olina okubuyisa mu baana bo.

Omuntu alina obulwadde bwa sickle cell ayinza kusuubira ki?

Abantu abalina obulwadde bwa sickle cell bayinza okuba n’obulamu obutono okusinga abantu bonna. Kyokka, obujjanjabi obupya obwa SCD bulongoosezza nnyo obulamu n’omutindo gw’obulamu . Singa obulwadde buno buddukanyizibwa bulungi, abantu abalina obulwadde bwa sickle cell basobola okuwangaala okutuuka mu myaka gyabwe egy’obukulu 50.

Omwana wange mmulabirira ntya singa aba alina obulwadde bwa sickle cell?

Omwana wo bw’aba alina obulwadde bwa sickle cell, waliwo ebintu bingi by’osobola okukola okuddukanya embeera ye:

• Bulijjo omwana mutwale ew’omusawo.
• Omwana wo muwe eddagala lyonna erigema mu budde.
• Yamba omwana wo dduyiro buli kiseera era alye emmere eyamba omutima .
• Bwe wabaawo obuzibu mu bulumi, omwana wo muwe amazzi mangi n’eddagala eriziyiza okuzimba eritali lya steroid (NSAID) . Singa obulumi tebusobola kufugibwa waka, twala omwana wo mu ddwaaliro afune eddagala ery’amaanyi eriweweeza ku bulumi.

Ddi lwe weetaaga okugenda mu kitongole ekijjanjaba abalwadde ab’amangu (ETU) ?

Obulwadde bwa sickle cell busobola okuleeta ebizibu eby’enjawulo ebiyinza okutta omuntu. Singa ggwe oba omwana wo mufuna obubonero bwonna ku buno wammanga, kuba 911 oba genda mu kisenge ky’abalwadde ab’amangu (ER) ekikuli okumpi amangu ddala:

• Obulumi obw’amaanyi.
• Obubonero bw’okukendeeza ku musaayi ogw’amaanyi: okukoowa ennyo, okuziyira, n’okussa obubi.
• Omusujja ogusukka diguli 101.3 (diguli 38.5).
• Ebizibu by’okulaba.
• Okukaluubirirwa okussa.
• Okusituka kw’obusajja okumala essaawa nnya oba okusingawo (priapism).
• Obubonero bw’obulwadde bwa acute chest syndrome: okulumwa mu kifuba, okusesema, omusujja.
• Obubonero bw’okusannyalala: Okunafuwa okw’amangu ku ludda olumu olw’omubiri, okuzirika n’okubulwa amagezi.

Lwaki obulwadde bwa sickle cell buleeta obulumi?

Mu ngeri ennyangu, obutoffaali obumyufu obulinga ekikonde bufaanana ennukuta C, oba omwezi ogw’enjuba. Bwe zitambula mu misuwa gyo, zisibira ne ziziyiza omusaayi okutambula. Awo obulumi we bubaawo. Kilowoozeeko ng’akalippagano k’ebidduka ku luguudo.

Sickle cell bulwadde obuva ku busimu obuziyiza endwadde?

Nedda Wadde ng’obulwadde bwa sickle cell bulina ebimu ku bifaananyi by’endwadde z’abaserikale b’omubiri , abasawo tebatwala SCD ng’obulwadde obuva ku busimu obuziyiza endwadde. Batwala SCD ng'embeera y'obuzaale .

Obulwadde bwa sickle cell mbeera eriwo obulamu bwonna. Okusimbuliza obutoffaali obusibuka mu mubiri, ekiyinza okuwonya mu bujjuvu, tekisoboka bulijjo, era kya bulabe. Wabula okuzuula amangu n’okujjanjaba kiyinza okuyamba okukendeeza ku bubonero n’okukendeeza ku bulabe bw’okufuna ebizibu. Bw’oba ​​ojjanjabiddwa buli kiseera, osobola okubeera n’obulamu obujjuvu era obw’okukola ennyo.

N’ekisembayo, ebintu ebikulu by’olina okujjukira (Take-Home Message) .

Okay, kale twogedde nnyo ku bulwadde bwa sickle cell. Bino bye bimu ku bintu ebikulu by’olina okujjukira:

• Obulwadde bwa sickle cell disease (SCD) bulwadde bwa musaayi obusikira nga mu kino enkula y’obutoffaali obumyufu ekyuka, ekivaako obuzibu mu kutambula kw’omusaayi.
• Ensonga enkulu lwaki kino kibaawo ye kika kya hemoglobin ekitali kya bulijjo ekiyitibwa hemoglobin S.
• Obulumi, okukendeera kw’omusaayi, yinfekisoni, n’okwonooneka kw’ebitundu by’omubiri bitera okubaawo.
• Okuzuula amangu n’okujjanjaba obulungi kikulu nnyo. Abalongo abaakazaalibwa bakeberebwa kino.
• Wadde ng’okusimbuliza obusigo bw’amagumba kiyinza okuba ekiwonya, naye tekisaanira buli muntu. Waliwo obujjanjabi obulala, gamba ng’eddagala n’okuteekebwamu omusaayi.
• Osobola okubeera obulungi n’obulwadde buno ng’okyusakyusa mu bulamu bw’omuntu, ng’ogoberera amagezi amatuufu ag’abasawo, era ng’okola mangu mu mbeera ey’amangu .

Bw’oba ​​ggwe oba omuntu gw’omanyi alina ekibuuzo kyonna ku bulwadde bwa sickle cell, kakasa nti ogenda ew’omusawo akuwe amagezi. Tewali kintu kya kutya wadde okuswala. Ekisinga obukulu kwe kutegeezebwa! Obulwadde bwa sickle cell, hemoglobin, obutoffaali obumyufu, okukendeeza omusaayi, endwadde z’obuzaale, obuzibu bw’obulumi, obujjanjabi bwa sickle cell