Ka tuyige ku ddagala lya Aldesleukin (IL-2) n’engeri gye likulu mu kujjanjaba kookolo.

Tukimanyi nti okujjanjabibwa kookolo kiyinza okuba omulimu omuzibu ennyo. Kitera okubaawo ebibuuzo okujja mu birowoozo byo ng’omusawo ayogedde ku ddagala eppya. Leero, tugenda kwogera ku ddagala erimu ery’enjawulo eritta kookolo, Aldesleukin. Era oluusi kiyitibwa IL-2. Ka tulabe eddagala lino kye liri, kiki kye likola ne by’olina okumanya ku lyo ng’olimira.

Aldesleukin ddagala lya ngeri ki?

Mu ngeri ennyangu, Aldase ddagala lya kookolo. Naye si nga ddagala lya kemiko lye tutera okuwulira. Mu butuufu ddagala lya busimu obuziyiza endwadde . Ekyo kitegeeza nti mu kifo ky’okutta obutereevu obutoffaali bwa kookolo, kisitula abaserikale b’omubiri gwo era ne kibawa amaanyi okulwanyisa obutoffaali bwa kookolo . Kiba ng'okutendeka "abaserikale" (immune cells) mu mibiri gyaffe ne tubasindika mu lutalo n'omulabe ayitibwa kookolo.

Eddagala lino (erinnya ly’ekika: Proleukin) lisinga kukozesebwa ku:

• Ku kookolo w'obutoffaali bw'ekibumba omutono oba ow'omulembe .
• Ku melanoma agenda mu maaso, kookolo w’olususu ow’amaanyi.

Mu mbeera ezimu, abasawo bayinza n’okuteesa ku ddagala lino ku bika bya kookolo ebirala.

Ebintu ebikulu by’olina okubuulira omusawo nga tonnatandika bujjanjabi

Nga tonnasalawo oba obujjanjabi buno bukusaanira, kikulu okutegeeza omusawo wo ku byafaayo byo byonna eby’obulamu. Kakasa nti obabuulira ku mbeera yonna ku zino wammanga naddala:

• Bw’oba ​​olina obuzibu bwonna obw’omusaayi (e.g. obuzibu bw’okuzimba omusaayi, okukendeera kw’omusaayi).
• Singa buli kiseera owulira ng'okooye oba ng'okooye .
• Bw’oba ​​olina dda omusujja oba embeera endala ey’okusiiga mu mubiri.
• Bw’oba ​​olina obulwadde bwonna obw’omutima, amawuggwe, ekibumba oba ekibumba .
• Bwoba olina ebizibu ebirala eby'abaserikale b'omubiri .
• Bw’oba ​​olina obulwadde bw’obwongo (e.g. okwennyamira) oba ng’omira eddagala.
• Bwoba nga emabegako okyusiddwa ebitundu by'omubiri .
• Bwoba olina okukonziba .
• Bw’oba ​​olina obuzibu mu lubuto oba endwadde z’enkola y’okugaaya emmere.
• Bwoba olina obuzibu mu thyroid .
• Bw’oba ​​olina alergy eri aldesleukin oba eddagala eddala lyonna, emmere oba langi .
• Bw’oba ​​oli lubuto, ng’ogezaako okufuna olubuto, oba ng’oli maama ayonsa .

Amawulire gano makulu nnyo eri obukuumi bwo, kubanga kwesigama ku mawulire gano omusawo kw’ajja okusalawo ku bujjanjabi obusinga okukusaanira era obusinga okuba obw’obukuumi.

Eddagala lino linaakuweebwa litya?

Lino si ddagala ly’osobola okutwala awaka. Aldase aweebwa mu ddwaaliro oba mu ddwaaliro, ng’alabirirwa nnyo abasawo ne ba nurse . Kitera okuweebwa ng’empiso mu musuwa (mu misuwa oba mu IV) . Oluusi era asobola okuweebwa ng’empiso wansi w’olususu (empiso wansi w’olususu).

Bw’oba ​​olowooza nti mu butanwa wanywa eddagala erisukkiridde, tegeeza omusawo oba nnansi mu bwangu. Mu mbeera yonna ey’amangu, osobola okugenda mu kitongole ky’eddwaaliro ekikola ku bujjanjabi obw’amangu (ETU) , era singa wabaawo ekizibu ky’obutwa, osobola okukuba essimu mu National Poisons Information Center mu ddwaaliro ly’eggwanga erya Colombo .

Weegendereze eddagala eddala ly’omira.

Bw’oba ​​omira eddagala lya aldesleukin, kikulu okubuulira omusawo wo ku ddagala eddala lyonna ly’omira. Eddagala erimu liyinza okukwatagana n’obujjanjabi buno. Kale, olina okutwala:

• Eddagala eddala eriweweeza ku kookolo (e.g. doxorubicin, methotrexate) .
• Eddagala eritta obuwuka naddala aminoglycosides
• Eddagala eriwonya puleesa (e.g. beta blockers) .
• Eddagala ly‟obulamu bw‟obwongo (olw‟okwennyamira, okweraliikirira) .
• Ebika by’eddagala eriweweeza ku bulwadde (e.g. prednisone, cortisone) .
• Eddagala eriweweeza ku bulumi naddala erya NSAID (e.g. ibuprofen, naproxen) .
• Empeke z’okwebaka
• Eddagala eddala eriziyiza obusimu obuziyiza endwadde nga interferon alfa

Ng’oggyeeko olukalala luno, tewerabira okubuulira omusawo wo ku vitamiini yonna, ebirungo by’ebimera by’omira, n’okuba onywa sigala oba onywa omwenge .

Ebintu by’olina okussaako essira mu ngeri ey’enjawulo ng’ojjanjabwa

• Okulondoola obutasalako: Ojja kulondoolwa nnyo abasawo ne ba nurse mu bbanga lyonna ery’obujjanjabi buno.
• Okukebera omusaayi: Ojja kwetaaga okwekebeza omusaayi buli kiseera okulondoola enkulaakulana y’obujjanjabi bwo n’okuzuula ebizibu ebivaamu nga bukyali.
• Okwekuuma obutakwatibwa yinfekisoni: Eddagala lino liyinza okukendeeza ku busobozi bw’omubiri okulwanyisa endwadde okumala akaseera. N'olw'ekyo,Fuba okwewala abantu abalina omusujja oba ssennyiga. Bw’ofuna omusujja oba yinfekisoni ng’omira eddagala, tewejjanjaba era tegeeza omusawo mu bwangu.
• Ebitera okutawaanya: Kya bulijjo okuwulira nga tolina mirembe katono oba ng’oli mulwadde ng’omira eddagala lino. Kino kitundu ku bujjanjabi. Kyokka, tegeeza omusawo wo ku bubonero oba ebizibu byonna ebipya by’ofuna.

Biki ebiyinza okuva mu ddagala lino?

Okufaananako n’eddagala lyonna, aldesleukin asobola okuleeta ebizibu. Ebimu ku bino byetaaga okujjanjabibwa amangu, ate ebirala si bya maanyi nnyo.

Bw’ofuna obubonero obulala obutali bwa bulijjo obutayogerwako mu lukalala luno, nsaba otegeeze omusawo wo oba nnansi wo nabyo.