Kya bulijjo okuwulira ng’otya katono n’okutya ng’oli oba omuntu wo anaatera okutandika obujjanjabi bwa kookolo. Naddala bw’owulira ku ddagala eriyitibwa ‘chemotherapy’, ebintu bingi ebijja mu birowoozo byo. Leero tugenda kwogera ku mpiso ey’enjawulo ekozesebwa mu kujjanjaba kookolo ng’oyo. Eryo lye ddagala eriyitibwa Asparaginase Erwinia Chrysanthemi (Recombinant) erijja wansi w’erinnya lya Rylaze. Engeri erinnya lino gye lizibu katono, tujja kumala kuliyita Rylaze. Ekitundu kino kijja kugezaako okuddamu ebibuuzo byo ku ddagala lino mu ngeri ennyangu.
Rylaze (Asparaginase) kye ki?
Mu ngeri ennyangu, lino ddagala lya ddagala eriweebwa okutta obutoffaali bwa kookolo. Tekozesebwa ku kookolo yenna, wabula ekozesebwa nnyo ku bika bibiri ebya kookolo eyeekuusa ku musaayi. Bino bye bino:
- Obulwadde bw’omusaayi obuyitibwa Acute Lymphoblastic Leukemia (ALL) .
- Obulwadde bwa Lymphoblastic Lymphoma
Eddagala lino likola mu ngeri eyeewuunyisa ennyo. Obutoffaali bwa kookolo bwetaaga amino acid eyitibwa asparagine okukula. Obutoffaali obulamu obwa bulijjo mu mubiri gwaffe busobola okufuula ono asparagine yennyini. Naye obutoffaali buno obwa kookolo wa leukemia ne lymphoma tebulina busobozi obwo. Kale eddagala lino erya Rylaze limenya ne lisaanyaawo asparagine ono mu musaayi. Olwo obutoffaali bwa kookolo ne bufiirwa emmere gye bwetaaga ne bufa. Obutoffaali obulamu busobola okukola asparagine gwe beetaaga, n’olwekyo tebukosebwa nnyo.
Ebintu by’olina okubuulira omusawo nga tonnatandika kumira ddagala
Nga tonnatandika bujjanjabi buno, kikulu nnyo okutegeeza omusawo wo ku byafaayo byo byonna eby’obulamu. Kakasa nti omubuulira bw’oba olina obukwakkulizo bwonna ku buno wammanga:
| Embeera y’obulamu bwo | Lwaki kikulu okukitegeezaako? |
|---|---|
| Obuzibu mu kuvaamu omusaayi oba obuzibu mu kuzimba omusaayi | Eddagala lino liyinza okukosa enkola y’omusaayi okuzimba. |
| Ekirwadde ekya sukaali | Eddagala lino liyinza okuvaako ssukaali okulinnya mu musaayi. |
| Bw’oba olina obulwadde bw’olubuto | Eddagala lino teritera kuleeta bulwadde bwa pancreatitis. |
| Obulwadde bw’ekibumba | Eddagala lino liyinza okukosa enkola y’ekibumba. |
| Alergy eri eddagala, emmere oba langi | Okukebera obulabe bw’okulwala alergy eri eddagala. |
| Bw’oba oli lubuto oba ng’ogezaako okufuna olubuto | Kino kikulu nnyo . Eddagala lino liyinza okukosa omwana ali mu lubuto. |
| Singa omwana ayonsebwa | Eddagala lino liyinza okuyita mu mata g’amabeere okutuuka ku mwana. |
Nnyinza ntya okukuwa eddagala lino?
Lino si ddagala ly’osobola okutwala awaka. Kikuweebwa abasawo abatendeke mu ddwaaliro oba mu ddwaaliro . Kitera okuweebwa ng'empiso mu kinywa .
Kikulu nnyo okumira eddagala lyo ku nnaku ezikutegekeddwa. Ennaku zino tozibuuka olw’ensonga yonna. Singa olw’ensonga ezimu tosobola kumira ddagala lyo ku lunaku olutegekeddwa, kuba essimu mangu omusawo omutegeeze.
Okuva eddagala lino bwe liweebwa wansi w’obulabirizi bw’omusawo, tewali mukisa gwa ‘overdose’. Kyokka bw’oba owulira nga tolina mirembe mu ngeri etaali ya bulijjo ng’omaze okumira eddagala, tegeeza abasawo mu bwangu. Mu mbeera ey’amangu, osobola n’okukuba essimu ekitongole kya National Poison Information Center mu ddwaaliro ly’eggwanga erya Colombo National Hospital .
Ebintu by’olina okulowoozaako ng’ojjanjabwa
Okulabirirwa kw’abasawo buli kiseera
Abasawo bajja kulondoola nnyo embeera yo mu kiseera kyonna ky’omala ng’omira obujjanjabi buno. Bagenda kulagira okukeberebwa omusaayi buli kiseera . Bajja kukebera okulaba oba eddagala likola, oba likosezza ekibumba kyo, ne ssukaali bw’ali mu musaayi.
Okufuna embuto n’okuyonsa
Eno nsonga ya kweraliikirira nnyo.
Tofuna lubuto ng’omira eddagala lino. Weewale okufuna olubuto okumala waakiri emyezi 3 ng’omaze okuyimiriza eddagala.
Empeke z’obusimu eza bulijjo eziziyiza okuzaala ziyinza obutakola bulungi n’eddagala lino. N’olwekyo, kakasa nti oyogera n’omusawo wo ku nkola endala etali ya bulabe ey’okuziyiza okuzaala ekusaanira. Eddagala lino liyinza okuleeta obulabe obw’amaanyi ku mwana ali mu lubuto.
Ekirala weewale okuyonsa omwana ng’omira eddagala lino n’okumala wiiki emu ng’omaze okulekera awo.
Okubeera nga omanyi eddagala eddala
Buulira omusawo wo ku ddagala lyonna ly’omira. Kuno kw’ogatta eddagala eriwonya embeera endala, vitamiini, eddagala eriweweeza ku bulumi, eddagala ly’ebimera, eddagala lya Ayurvedic, n’ebirungo ebiyamba omubiri. Eddagala erimu liyinza okukwatagana ne Rylaze. Okugeza nga:
- Eddagala eriyitibwa corticosteroids (e.g. Prednisolone) .
- Eddagala lya Methotrexate
- Vincristine, omusajja ayitibwa Vincristine
- Eddagala lya Zonisamide
- Ekirungo kya Cytarabine
- Obusimu obuyitibwa thyroid hormones
Olukalala luno terujjuvu, n’olwekyo kikulu nnyo okubuulira omusawo wo ku buli ky’omira.
Ebizibu ebiyinza okuva ku ddagala
Okufaananako n’eddagala lyonna, kino kiyinza okuvaako ebizibu. Si buli muntu nti azifuna. Wabula kino kikulu okukimanya osobole okukola amangu singa wabaawo obubonero bwonna.
| Side effect | Obubonero bw’olaba |
|---|---|
| Ebizibu eby’amaanyi ebirina okuloopebwa eri omusawo oba abakozi b’eddwaaliro mu bwangu | |
| Obulwadde bwa alergy | Okusiiyibwa ku lususu, okusiiwa, okuzimba mu maaso, emimwa, olulimi, okukaluubirirwa okussa. |
| Okuvaamu omusaayi mu ngeri etaali ya bulijjo | Omusulo omuddugavu oba ogulimu omusaayi, omusulo omumyufu/kitaka omuddugavu, okusesema okufaanana ng’omubisi gwa kaawa, okuvaamu omusaayi mu nnyindo/ennyindo, amabala amamyufu ku lususu. |
| Okuzimba omusaayi | Obulumi mu kifuba, okussa obubi, okulumwa amagulu, okuzimba oba ebbugumu. |
| Obulwadde bw’olubuto | Obulumi obw’amaanyi mu lubuto olwa waggulu, okubumbulukuka okutuuka ku mugongo, omusujja, okuziyira n’okusiiyibwa. |
| Obuvune mu kibumba | Okufuuka okwa kyenvu kw’amaaso n’olususu (jaundice), omusulo ogwa kyenvu/kitaka omuddugavu, obulumi mu ludda olwa waggulu olwa ddyo olw’olubuto, okukoowa ennyo. |
| Ssukaali omungi mu musaayi | Enjala okweyongera mu ngeri etaali ya bulijjo, ennyonta esukkiridde , okufulumya omusulo ennyo, okulaba obubi, obukoowu obuyitiridde. |
| Ebizibu ebitera obutaba bya maanyi, naye nga birina okuloopebwa eri omusawo singa bisigala | |
| Okulumizibwa omutwe | Okulumwa omutwe okwa bulijjo. |
| Endya | Okubulwa okwagala okulya. |
| Obulumi mu binywa | Obulumi bw’omubiri. |
| Amabwa mu kamwa | Amabwa amatono munda mu kamwa. |
Bw’ofuna obubonero obulala obutali bwa bulijjo obutali ku lukalala luno, nsaba otegeeze omusawo wo naye.
Obubaka Obutwala Awaka
- Rylaze (Asparaginase) mpiso ya ddagala erikozesebwa okujjanjaba kookolo w’omusaayi ayitibwa leukemia ne lymphoma.
- Eddagala lino liweebwa mu ddwaaliro oba mu ddwaaliro nga lilabirirwa abasawo.
- Buulira omusawo wo ku mbeera zonna ez’obujjanjabi n’eddagala eddala lyonna ly’omira.
- Bw’ofuna ebizibu byonna eby’amaanyi ng’obubonero bwa alergy, okuvaamu omusaayi mu ngeri etaali ya bulijjo, oba okulumwa ennyo mu lubuto, genda mangu omusawo amagezi.
- Weewale ddala okufuna olubuto ng’ojjanjabibwa n’okumala emyezi 3 oluvannyuma.
- Bw’oba olina ekibuuzo kyonna oba ekikweraliikiriza, totya kwogera na musawo wo. Baliwo okukuyamba.
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