Chordoma: Ka tuyige ku kookolo ono atatera kulabika era akula mu mugongo.

Wali owuliddeko ku linnya lya 'Chordoma'? Oboolyawo si bwe kiri. Kubanga embeera etatera kulabika nnyo, kwe kugamba, embeera embi etatera kulabibwa. Ekizimba kino ekya kookolo kikula mu bifo bibiri ebikulu ennyo mu mubiri gwaffe. Ekimu gwe mugongo gwaffe, ate omulala gwe musingi gw’ekiwanga kyaffe. Kiba kya magezi okuwulira ng’otya katono ng’ekigambo kookolo kyogerwako mu kifo ng’ekyo. Naye teweeraliikiriranga. Tujja kwogera ku buli kimu mu ngeri ennyangu, entegeerekeka era etegeerekeka gy’oli.

Mu ngeri ennyangu, Chordoma kye ki?

Chordoma kookolo akula mu magumba gaffe. Okubeera omutuufu, kiri mu kibinja kya kookolo ekiyitibwa sarcomas. Kookolo akula mpola nnyo. Kino kitegeeza nti kiyinza okusigala nga tekirina bubonero okumala ebbanga eddene.

Kookolo ono asobola okukula wonna mu mugongo, naye waliwo ebifo bisatu ebisinga okubeerawo:

• Ekitundu ekisinga wansi mu mugongo (Sacrum): Ebitundu nga 35% ku chordomas zonna zikula mu kitundu kino.
• Skull base: Ebitundu ebirala 35% ku balwadde bakula wano. Eggumba eriri mu kifo kino liyitibwa ‘clivus’. Ekika kino era kiyitibwa ‘clival chordomas’.
• Emigongo emirala egy’omugongo: Ebitundu 30% ebisigadde bibeera mu bitundu by’omugongo ebirala. Zisinga kubeera mu mugongo ogw’okubiri ogw’omumwa gwa nnabaana, ne ziddirira omugongo gw’omugongo n’ogw’omu kifuba.

Okusoomoozebwa okusinga obunene ku kookolo ono kwe kuba nti, wadde akula mpola, alumba ebitundu ebikulu eby’obusimu obumwetoolodde. Kino kitegeeza nti kiyinza okwonoona ebitundu ebizibu ennyo ng’obwongo n’omugongo.

Ekirala kiri nti erina omuze gwa waggulu okuddamu, ne bwe guba gujjanjabiddwa. Kitera okudda mu kifo kye kimu kye kyali edda. Era, mu bitundu nga 30% - 40%, kookolo ono asobola okusaasaana (okusaasaana) mu bitundu by’omubiri ebirala. Bwe kiba bwe kityo, kisinga kusaasaana ku:

• Eri mu mawuggwe
• Ku nnywanto z’amazzi ezigyetoolodde
• Ku magumba amalala
• Ku kibumba
• Ku lususu

Waliwo ebika bya Chordoma?

Yee, ekitongole ky’ebyobulamu mu nsi yonna (WHO) kizudde ebika bya kookolo ono ebikulu bisatu. Ensengeka zino zeesigamiziddwa ku ngeri obutoffaali bwa kookolo gye bulabika wansi wa microscope (histology). Ka tulabe kye bali.

Ani asinga okulwala obulwadde buno? Kitera kitya?

Wadde ng’obulwadde bwa chondroma busobola okukula ku myaka gyonna, businga kubeera mu bantu abakulu abali wakati w’emyaka 50 ne 80. Ekitundu ekitono ku buli kikumi, nga 5%, bubufuna mu baana. Ekirala, abasajja emikisa gy’okukwatibwa obulwadde buno emirundi nga 1.5 okusinga abakyala.

Kino tekitera kubaawo nnyo ne kiba nti omuntu omu yekka ku buli bukadde (100,000) mu bantu b’afuna obulwadde buno buli mwaka . Kino kitegeeza nti ne mu nsi nga yaffe, abapya batono nnyo abakwatibwa buli mwaka.

Bubonero ki obulaga kino?

Chordoma bw’egenda ekula, eteeka puleesa ku bwongo oba omugongo ogugyetoolodde. Puleesa eno ereeta obubonero. Ate era obubonero buyinza okwawukana okusinziira ku kifo ekizimba we kiri.

Ka tulabe mu kipande wansi engeri obubonero gye bwawukana okusinziira ku kifo ekizimba we kiri.

Lwaki kookolo ow’ekika kino afuna? Kiki ekivaako?

Abanoonyereza bakyalemeddwa kuzuula kituufu ekivaako, naye balowooza nti enkyukakyuka mu buzaale obuyitibwa TBXT zeenyigiddemu.

Lowooza ku kino, omwana bw’aba asoose okukula mu lubuto lwa maama, ng’omugongo tegunnakula, akagumba akatono akayitibwa notochord kakola. Kino kye kijja okukulaakulana oluvannyuma ne kifuuka omugongo. Ebiseera ebisinga, notochord eno ebula ddala omwana w’aweza wiiki nga 8.

Naye si bulijjo nnyo, obumu ku butoffaali buno busobola okusigala mu musingi gw’ekiwanga oba mu magumba g’omugongo. Kiteeberezebwa nti oluvannyuma, singa wabaawo enkyukakyuka mu ggiini ya TBXT gye twayogeddeko, obutoffaali buno obusigaddewo busobola okutandika okukula nga tebufugibwa ne bufuuka kookolo wa chondroma.

Ate era, abantu abalina embeera y’obuzaale ey’obulwadde bwa tuberous sclerosis bali mu bulabe bwa maanyi katono obw’okulwala chordoma.

Ozuula otya obulwadde buno? (Okuzuula obulwadde)

Bw’oba ​​olina obubonero obulagiddwa waggulu, olina okusooka okulaba omusawo. Omusawo ajja kukubuuza ku bubonero bwo n’ebyafaayo byo eby’obujjanjabi. Olwo, bajja kukola okukebera omubiri n’okukeberebwa obusimu.

Singa kiteeberezebwa nti waliwo ekizimba kya kookolo, omusawo ajja kukusindika okukeberebwa ebifaananyi.

• X-ray
• Okukebera kompyuta (CT) mu ngeri ya Computed Tomography
• Sikaani y’okukuba ebifaananyi mu ngeri ya magineeti (MRI).

Oluvannyuma lw’okukeberebwa kuno, kirabika ojja kusindikibwa ew’omusawo mukugu mu kookolo w’amagumba. Kiyinza okwetaagisa okwongera okukeberebwa okukakasa obulwadde buno n’okulaba oba busaasaanidde mu bitundu by’omubiri ebirala.

Engeri yokka ey’okukakasa 100% ku bulwadde buno kwe kukola biopsy , nga kino kizingiramu okuggya sampuli entono ennyo ey’ebitundu by’omubiri okuva mu kizimba nga okozesa empiso entono n’okyekebejja wansi wa microscope.

Kijjanjabwa kitya?

Obujjanjabi obukulu era obusinga obulungi ku chordoma kwe kulongoosa. Ebisinga obulungi eri omulwadde bituukibwako nga baggyawo ekizimba kya kookolo ekinene nga bwe kisoboka (en bloc resection).

Naye kino si kyangu nga bwe kirabika kubanga, nga bwe twayogeddeko emabegako, ebizimba bino bikola okumpi n’ebitundu n’obusimu ebikulu ennyo, ebikulu.

• Ebizimba ku musingi gw’ekiwanga: Bino kizibu nnyo okubiggyawo ddala kubanga bibeera kumpi n’ekikolo ky’obwongo, obusimu obukulu, n’emisuwa.
• Ebizimba by’omugongo: Bino bisobola okulumba omugongo, obusimu n’emisuwa eminene. Singa bino byonoonebwa nga balongoosebwa, obulemu obw’olubeerera oba n’okufa buyinza okubaawo.

N’olwekyo, abasawo abalongoosa obusimu bagezaako okuggyawo ekizimba nga bwe kisoboka nga tebatuusizza bulabe ku mulwadde.

Kookolo wa chordoma ebiseera ebisinga taddamu bulungi ku bujjanjabi bwa radiation ne chemotherapy, n’olwekyo bino tebitera kukozesebwa ng’obujjanjabi obusookerwako. Wabula obujjanjabi bwa radiation buweebwa oluvannyuma lw’okulongoosebwa okusaanyaawo obutoffaali bwa kookolo bwonna obusigaddewo n’okukendeeza ku bulabe bwa kookolo okudda.

Mu kiseera kino abanoonyereza bali mu kunoonyereza ku bujjanjabi obw’omulembe nga targeted therapy ne immunotherapy.

Obulwadde buno butegeeza ki?

"Okuteebereza" kwe kuteebereza emikisa gy'okuwona n'okuwona obulwadde. Mu mbeera y’obulwadde bwa chondroma, kino kisinziira ku bintu ebiwerako:

• Ekifo ekizimba we kiri n’obungi bwe bwaggyibwawo nga balongoosebwa: Singa ekizimba kyaggyibwawo ddala, ebivaamu biba birungi.
• Oba kookolo asaasaana (metastasized):Singa eba esaasaanidde mu bitundu by’omubiri eby’ewala, omuwendo gw’abawona gukendeera.
• Emyaka nga bazuuliddwa: Ebivaamu biyinza okuba wansi katono mu bantu abasukka mu myaka 60.
• Ekika kya kookolo: Ebika ebya bulijjo biba n'ebivaamu ebirungi okusinga ebika eby'obusungu nga "Dedifferentiated" bye twayogeddeko.

Okusinziira ku kunoonyereza okumu, emiwendo gy’abalwadde ba chordoma abawangaala giri bwe giti:

• Oluvannyuma lw’emyaka 3: 80.5%
• Oluvannyuma lw’emyaka 5: 68.4%
• Oluvannyuma lw’emyaka 10: 39.2%

Obulwadde buno busobola okuziyizibwa? Ddi lwe nnina okulaba omusawo?

Tewali kye tuyinza kukola kuziyiza bulwadde bwa chondroma okukula. Emisango egisinga gibaawo mu ngeri ya kimpowooze. Singa omuntu mu maka go alina obulwadde bwa chondroma oba tuberous sclerosis, kikulu okwekebeza abasawo buli kiseera.

Ekisinga obukulu kwe kugoberera okumala ebbanga eddene ng’omaze okujjanjabibwa. Chondroma kookolo asobola okuddamu ne bwe wayise emyaka mingi ng’ajjanjabiddwa. N’olwekyo, kyetaagisa okugenda okwekebejjebwa buli kiseera nga ttiimu y’abasawo bw’ekuwa amagezi.

Bw’ofuna obubonero bwonna obupya oba singa obubonero bwo bweyongera, laba omusawo mu bwangu.

Kya bulijjo okuwulira ng’otya n’okuzitoowererwa ng’oyiga ku kookolo atatera kubaawo bw’otyo. Naye jjukira nti ttiimu yo ey’abasawo ejja kukolagana naawe okukukolera enteekateeka y’obujjanjabi esinga obulungi era bakole kyonna ekisoboka okutumbula omutindo gw’obulamu bwo.