Wali owuliddeko ku ffene eyeekukuma mu mubiri gwo? Ka tuyige ku bulwadde bwa Cryptococcosis!

Wali owuliddeko ku bulwadde obuyitibwa Cryptococcosis? Erinnya lino liyinza okuwulikika ng’ekyewuunyisa katono, era n’okutiisa katono. Naye teweeraliikiriranga. Buba yinfekisoni eva ku ffene. Ffenna tukwatibwa ebintu bingi mu butonde bwaffe, era ne ffene zino bwe zityo. Kale, leero tugenda kwogera ku mbeera eno eyitibwa Cryptococcosis mu ngeri ennyangu gy’osobola okutegeera.

Ddala Cryptococcosis kye ki?

Mu ngeri ennyangu, cryptococcosis bwe buba ekika kya ffene ekiyitibwa Cryptococcus bwe kiyingira mu mubiri gwo ne kireeta yinfekisoni naddala mu bwongo oba mu mawuggwe. Oluusi kiyinza okusaasaana mu bitundu by’omubiri ebirala, bye tuyita disseminated cryptococcosis .

Teebereza, singa obuwuka buno obwa Cryptococcus bukwata obwongo bwo, embeera eno eyitibwa cryptococcal meningitis . Olwo osobola okufuna ebintu ng’omusujja, okulumwa omutwe ennyo, n’okulumwa ensingo. Ate era, bwe kikwata amawuggwe go, kiyitibwa cryptococcal pneumonia oba pulmonary cryptococcosis . Olwo osobola okufuna obubonero ng’okusesema n’okukaluubirirwa okussa.

Waliwo n’ebika bya ffene ebya Cryptococcus eby’enjawulo.

• Cryptococcus neoformans: Ekika kino kitera okukwata abantu abalina abaserikale b’omubiri abanafuye. Kwe kugamba, abo abalina obusobozi bw’omubiri okuziyiza endwadde obutono be basinga okubukosebwa.
• Cryptococcus gattii: Naye ekika kino kiyinza okukulwaza ne bwe kiba nti abaserikale b’omubiri ba maanyi.

Bubonero ki obulaga kino? Oyinza otya okukitegeera?

Obubonero bwa cryptococcosis businziira ku wa mu mubiri gwo ffene w’akwata. Singa bukosa amawuggwe, oyinza okufuna obubonero obufaananako n’obulwadde bw’ekifuba, ate singa bukosa obusimu obw’omu makkati (obwongo n’omugongo), oyinza okufuna obubonero obufaananako n’obulwadde bw’okuzimba omutwe. Mu bulwadde bwa cryptococcosis obusaasaanyiziddwa, obubonero busobola okulabika mu bitundu by’omubiri eby’enjawulo.

Obubonero bw’obulwadde bw’amawuggwe (Cryptococcal pneumonia):

• Okukolola
• Okukaluubirirwa okussa, okuwulira ng’oziyira
• Obulumi mu kifuba
• Omusujja

Obubonero bw’obulwadde bw’obusimu obw’omu makkati (Cryptococcal Meningitis):

• Omusujja
• Omutwe ogw’amaanyi
• Okulumwa ensingo oba okukaluba (nnyo nga tosobola kuteeka kalevu ku kifuba) .
• Ekikeeto
• Okusesema
• Okuwulira ekitangaala (obuzibu okulaba mu kitangaala ekitangaavu) .

Obubonero bw’obulwadde bwa cryptococcosis obusaasaana mulimu:

Bw’oba ​​olina obulwadde bwa cryptococcosis obusaasaanyiziddwa, oyinza okulaba enkyukakyuka mu lususu ng’oggyeeko obubonero obukwata ku mawuggwe oba obusimu obw’omu makkati. Okugeza nga:

• Ebitundu ebinene oba ebikalu (ebipande) .
• Ebizimba
• Amabwa
• Ebikonde
• Ebizimba ebizimba

Lwaki obulwadde bwa Cryptococcosis bubaawo?

Ekisinga okuvaako obulwadde buno bye bika bya ffene bibiri , Cryptococcus gattii (C. gattii) ne Cryptococcus neoformans (C. neoformans) . Enkwaso zino zibeera mu butonde - naddala mu ttaka, ebikoola by’emiti, n’omusulo gw’ebinyonyi naddala omusulo gw’ejjiba.

Lowooza ku kino, oluusi bwe tukola mu bifo ebirimu enfuufu, okumpi n’ebizimbe eby’edda oba mu nsuku, obuwuka buno obwa ffene busobola okuyingira mu mibiri gyaffe.

Enkwaso zino, `C. gattii` ne `C. neoformans`, zisangibwa mu bitundu by’ensi eby’enjawulo. `C. gattii` etera nnyo mu Australia, British Columbia, Canada, Pacific Northwest ya Amerika, ne Southeast Asia.

Kino okifuna otya?

Obulwadde bwa Cryptococcosis buva ku kussa mu mpewo obuwuka obuyitibwa fungus Cryptococcus. Bino tebirabika na maaso, era kiyinza okukuzibuwalira okubyewala singa oba obeera mu kitundu ekiwuka kino mwe kiri.

Ekikulu abantu abasinga abassa ffene ono tebafuna bubonero bwonna. Naye abantu abamu ffene atandika okukula mu mawuggwe gaabwe, oba okuyita mu mubiri okutuuka ku bwongo n’ebalwaza. Oluusi enkwaso esobola okubeera mu mawuggwe okumala ebbanga eddene, naye ekula n’ereeta obubonero ng’abaserikale b’omubiri banafuye olw’ensonga ezimu (okugeza, olw’obulwadde obulala oba eddagala ly’omira).

Kino kisiigibwa okuva ku muntu omu okudda ku mulala?

Nedda.Cryptococcosis si bulwadde obuyinza okusiigibwa okuva ku muntu omu okudda ku mulala. Tosobola kugikwata ku muntu alina akawuka.

Ani ali mu bulabe obw’amaanyi obw’okufuna kino?

Nga bwe twayogeddeko emabegako, ekika kya C. neoformans kisinga kuleeta bulwadde mu bantu abalina abaserikale b’omubiri abatali balongoofu. Kuno kw’ogatta:

• Abantu abalina akawuka ka siriimu .
• Abantu abalina ebika bya kookolo ebimu, okugeza lymphomas ne leukemias .
• Abantu ababadde bakyusiddwa obutoffaali obusibuka mu mubiri, ekitundu ky’omubiri oba obusigo bw’amagumba.
• Dozi nnyingi ez’eddagala lya corticosteroids okumala ebbanga eddeneAbantu abalina embeera ezeetaaga okumira eddagala (e.g., endwadde z‟amawuggwe ezimu ezitawona, obuzibu bw‟abaserikale b‟omubiri).

Naye, ekika kya `C. gattii` asobola okuleeta endwadde mu bantu abalina abaserikale b’omubiri abalamu nga kw’otadde n’abo abalina abaserikale b’omubiri abanafuye.

Kino kiyinza okuleeta bizibu ki?

Obulwadde bwa Cryptococcosis naddala ng’olina yinfekisoni mu bwongo bwo, busobola okuleeta ebizibu eby’amaanyi . Ebimu ku bino mulimu:

• Puleesa y’omutwe okweyongera: Kino kiva ku bungi bw’amazzi okwetooloola obwongo okweyongera, ne buteeka puleesa esukkiridde ku bwongo. Singa tebujjanjabwa bulungi, kiyinza okukosa obwongo.
• Okufiirwa okulaba ekitundu oba okufiirwa ddala.
• Endwadde z’amaaso oba embeera z’okuzimba.
• Obunafu bw’ebinywa ebifuga amaaso ( extraocular muscle paresis ).
• Okuddamu okulwala: Oluusi, obubonero bw’obulwadde bwa cryptococcosis busobola okuddamu oluvannyuma lw’okujjanjabwa.
• Immune Reconstitution Inflammatory Syndrome (IRIS): IRIS mbeera ng’abaserikale b’omubiri bo basusse okukola oluvannyuma lw’okujjanjabwa, ne kyongera obubonero. Businga kubeera mu bantu abalina akawuka ka siriimu, naye era busobola okubeerawo mu bantu abatalina siriimu.

Ozuula otya mu butuufu obulwadde buno?

Abasawo bazuula obulwadde bwa cryptococcosis nga bakebera ebitundu byo oba amazzi g’omubiri gwo okulaba oba temuli bubonero bwa ffene wa Cryptococcus. Bayinza okukola ebigezo bino wammanga:

• Omusaayi gwo.
• Amazzi g’omu bwongo (CSF ). Kino kifunibwa nga tuggya sampuli y’amazzi okuva mu mugongo (lumbar puncture).
• Amalusu (omusulo oguva mu mawuggwe nga gusesema).

Ng’oggyeeko okukeberebwa kuno, obubonero bwo, ebyafaayo by’obujjanjabi, ebyafaayo by’entambula, n’okukeberebwa ebifaananyi nabyo bisobola okuyamba okuzuula obulwadde. Okusinziira ku bubonero bwo, era oyinza okwetaaga okukeberebwa X-ray mu kifuba , CT scans (computed tomography scans) , oba MRI (magnetic resonance imaging) okunoonya enkyukakyuka mu mawuggwe oba mu bwongo.

Kino kikwatibwa kitya?

Abasawo bakozesa eddagala eritta obuwuka okujjanjaba obulwadde bwa cryptococcosis.. Obujjanjabi obw’enjawulo bw’ofuna bujja kusinziira ku kifo ekiwuka kya Cryptococcus ky’ali mu mubiri gwo n’obulamu bw’abaserikale b’omubiri gwo. Okugeza, omuntu alina obulwadde bwa cryptococcosis obw’amawuggwe obutono ayinza okwetaaga eddagala limu lyokka eritta enkwa. Wabula abantu abalina obulwadde obw’amaanyi ennyo oba cryptococcal meningitis bayinza okwetaaga obujjanjabi obw’amaanyi, ekitegeeza okumira eddagala eriwerako eritta obuwuka okumala ebbanga eddene.

Eddagala n’obujjanjabi obw’enjawulo obukozesebwa ku bulwadde bwa Cryptococcosis:

• Eddagala lya Fluconazole
• Ekirungo kya Amphotericin B (AmB) .
• Flucytosine eddagala eriyitibwa Flucytosine
• Corticosteroids (zino ziweebwa okufuga embeera ng’okuzimba obwongo) .
• Okulongoosa okuggyawo ebizimba ebinene ebya ffene (cryptococcomas).
• Therapeutic lumbar puncture oba shunts (special tubes) okukendeeza ku puleesa ku bwongo.

Kiki ky’osaanidde okusuubira singa ofuna obulwadde buno?

Okusinziira ku kifo w’okwatibwa n’engeri gy’olwadde, omusawo wo ayinza okwetaaga okukujjanjaba n’eddagala eritta obuwuka okumala wiiki oba emyezi okusobola okugoba obulwadde bwa cryptococcosis. Bw’oba ​​olina akawuka ka siriimu, omusawo wo era ayinza okwetaaga okukyusa eddagala lyo eriziyiza akawuka ka siriimu . Bw’oba ​​olina embeera endala enafuya abaserikale b’omubiri, okujjanjaba embeera eyo enkulu kiyinza okukuyamba okulwanyisa obulwadde bwa cryptococcosis.

Kino kisobola okuwona ddala?

Abantu abalina abaserikale b’omubiri abalamu ebiseera ebisinga basobola okuwona nga bakozesa eddagala eritta obuwuka. Kyokka abantu abalina abaserikale b’omubiri abanafuye bayinza okukaluubirirwa okubawonya. Oluusi, obubonero bwo buyinza okuddamu oluvannyuma lw’okujjanjabwa.

Kabi ki akali mu kufa olw’ensonga eno?

Omuwendo gw’abafa abalwadde ba cryptococcosis abajjanjabwa mu North America (nga mw’otwalidde ne Amerika ne Canada) gubalirirwamu ebitundu 20% . Kyokka mu bitundu ebimu ebya Afrika, omuwendo guno guyinza okutuuka ku bitundu 70% . Okusinziira ku kifo w’obeera mu nsi, obuweereza bw’ebyobulamu bw’ofuna bulina kinene kye bukola. Kino kitegeeza nti abantu abali mu bitundu by’ensi ebitali binywevu mu by’enfuna bali mu bulabe bwa maanyi obw’okufa endwadde nnyingi. Eno embeera ya nnaku.

Nnyinza ntya okwekuuma okuva ku kino? Kisoboka?

Bw’oba ​​obeera mu kitundu omuli Cryptococcus, kiyinza okukuzibuwalira okwewala okugissa.Wabula bw’oba ​​oli mu bulabe bwa maanyi obw’okulwala Cryptococcus, omusawo ayinza okukuwa amagezi bino wammanga:

• Okwekebejja okugendereddwamu: Nga tonnatandika kujjanjaba siriimu, omusawo ayinza okukukebera oba olaba Cryptococcus antigens (ebitundu bya ffene ebimanyiddwa) ne bw’oba ​​tolina bubonero bwa cryptococcosis. Singa ebyava mu kukeberebwa kwo biba birungi, bisobola okukujjanjaba obulwadde bwa cryptococcosis okukutangira okulwala ffene eyabeera edda mu mubiri gwo.
• Okwetangira: Bw’oba ​​oli mu bulabe obw’amaanyi obw’okulwala obulwadde bwa cryptococcosis, omusawo ayinza okukujjanjaba n’eddagala eritta obuwuka obuleeta endwadde. Kino kijja kukuyamba obutalwala singa oba ofunye obulwadde bwa Cryptococcus.

Nlabirira ntya obulamu bwange?

Ekisinga obulungi ky’oyinza okukola kwe kufuna obujjanjabi obutuufu ku mbeera yonna ey’obujjanjabi eyinza okuba ng’enafuya abaserikale b’omubiri. Kuuma enteekateeka z’abasawo bo buli kiseera. Babuuze engeri y’okutegeera obubonero obulaga nti omuntu alina obulwadde. Yogera nabo ku ngeri y’okwetangira yinfekisoni n’eky’okukola singa olowooza nti olina yinfekisoni.

Ddi lwe nnina okulaba omusawo?

Bw’oba ​​olina embeera enafuya abaserikale b’omubiri, gamba nga siriimu, buuza omusawo engeri gy’oyinza okwetangira okulwala. Bw’oba ​​n’abaserikale b’omubiri abanafuye era ng’olina obubonero bw’obulwadde bwa cryptococcosis oba yinfekisoni endala yonna, laba omusawo amangu ago.

Ddi lwe nnina okugenda mu kitongole ekijjanjaba abalwadde ab’amangu (ETU) ?

Bw’oba ​​olina obubonero bw’obulwadde obw’amaanyi, genda mangu mu kisenge eky’abalwadde ab’amangu. Obubonero buno buyinza okuli:

• Omusujja ogw’amaanyi (okusukka diguli 103 Fahrenheit/diguli 40 Celsius).
• Okukaluubirirwa okussa.
• Enkyukakyuka mu kulaba.
• Obulumi mu kifuba.
• Okukyuka langi ya bbululu mu lususu, emimwa oba enjala.
• Okusoberwa.
• Okukonziba.

Ekikulu: Bw’oba ​​n’abaserikale b’omubiri abanafuye, buuza omusawo obubonero bw’osaanidde okugenda mu kisenge ky’abalwadde ab’amangu. Oyinza okwetaaga obujjanjabi obw’amangu mu bwangu, ne bwe kiba nti obubonero bwo si bwa maanyi nnyo okusinga obwo obuwandiikiddwa wano.

Bibuuzo ki bye nnina okubuuza omusawo wange?

Kiyinza okuba eky’omugaso okubuuza omusawo wo ebibuuzo bino:

• Obulwadde buno bwa maanyi butya?
• Eddagala lyange ndimira ntya?
• Nze nneetaaga ebbanga ki okufuna obujjanjabi?
• Kiki kye nnyinza okukola okuziyiza yinfekisoni mu biseera eby’omu maaso?

Obubaka obusinga obukulu okutwala awaka

Obulwadde bwa Cryptococcosis bulwadde bwa ffene obuyinza okuba obw’amaanyi mu bantu abalina abaserikale b’omubiri abanafuye. Kyokka bw’oba ​​oli mu bulabe obw’amaanyi, omusawo ayinza okwagala okukukebera n’okukuwa eddagala eriziyiza. Era olw’enkulaakulana mu bujjanjabi, abantu abalina akawuka ka siriimu kati bali mu bulabe butono nnyo obw’okufuna endwadde ez’amaanyi. Bw’okolagana n’omusawo wo, osobola okukola enteekateeka ekukuuma ng’oli mulamu bulungi nga bwe kisoboka. N’olwekyo, tosattira, era tewerabira okunoonya amagezi g’abasawo bw’oba ​​olina ekikweraliikiriza.

` Cryptococcosis, obulwadde bwa ffene, omusujja gw’obwongo, obulwadde bw’amawuggwe, obutafaali obuziyiza endwadde, akawuka ka siriimu, eddagala eritta obuwuka