Olina ekizimba ekyewuunyisa ku mubiri gwo? Kyandiba nga kizimba kya butoffaali bwa buwuka? Ka twogere!

Wali owuliddeko ku 'Germ Cell Tumor'? Mpozzi erinnya liwulikika nga litiisa katono, naye tofaayo. Leero tugenda kukyogerako mu ngeri ennyangu gy'osobola okutegeera. Kubanga kikulu nnyo okubeera nga omanyi ebintu bino naddala nga oluusi bisobola okukula mu baana abato n’abato abakulu.

Ebizimba bino eby’obutoffaali bw’obuwuka bye biruwa?

Mu ngeri ennyangu, ekizimba ky’obutoffaali bw’obuwuka kizimba ekikula okuva mu butoffaali bwaffe obw’okuzaala, obuyitibwa ‘obutoffaali bw’obuwuka’. Ekigambo "obuwuka" kitegeeza "okumera" oba "okukula." Kati, mu muwala, obutoffaali buno obw’obuwuka oluvannyuma bujja kufuuka `amagi'. Mu mulenzi, bino bijja kufuuka `ensigo'. Kale, ebizimba bino eby’obutoffaali bw’obuwuka bisinga okukula mu bitundu amagi mwe gakolebwa, kwe kugamba `enkwaso’, n’ensigo we zikolebwa, kwe kugamba `ensigo’.

Wabula oluusi ebizimba bino bisobola okukula mu bitundu by’omubiri ebirala ng’oggyeeko enkwaso n’ensigo. Okugeza, zisobola okukula mu bifo ng’olubuto, ekifuba, omugongo ogwa wansi, eggumba ly’omukira, n’obwongo. Ebizimba ebikula mu bifo ebirala nga bino biyitibwa ebizimba eby'ebweru w'enjuba . Kwe kugamba, ebizimba ebikula ebweru w’endwadde z’okuzaala.

Ekisinga obukulu, ebizimba bino eby’obutoffaali bw’obuwuka bisinga kulabibwa mu baana abato, abatiini, n’abato abakulu .

Waliwo ebika by’ebizimba by’obutoffaali bw’obuwuka?

Yee, waliwo ebika bibiri eby’ebizimba by’obutoffaali bw’obuwuka. Ebimu biyinza okuba eby’obulabe , ekitegeeza nti biba bya kookolo. Ekika ekirala si kya bulabe . Ebika by’ebizimba byombi bisobola okukula ebinene. Kyokka ebizimba by’obutoffaali bw’obuwuka obuleeta kookolo byokka bye bisobola okusaasaana mu bitundu by’omubiri ebirala. Bwe zisaasaana (metastasized), zisobola okwonoona ebitundu byaffe eby’omunda era nga zizibu katono okuzijjanjaba.

Kati ka tulabe ebika ebikulu eby’ebizimba by’obutoffaali bw’obuwuka bye biruwa:

Obulwadde bwa Teratom

Bino kika kya bibala bya njawulo nnyo. Ebibala bino bisobola okubaamu ebitundu by’omubiri ng’amannyo, enviiri, ebinywa n’amagumba. Kilowoozeeko ng’ekibala ekikoleddwa mu bintu eby’enjawulo ebya buli ngeri. Bino biyinza okuba ‘ebikuze’ oba ‘ebitakuze’.

• Mature teratomas , oluusi eziyitibwa dermoid cysts , kye kika ky’ekizimba ky’obutoffaali bw’obuwuka ekisinga okubeera mu nkwaso. Ebiseera ebisinga, teziba na kookolo.
• Teratomas ezitakuze zitera kuba za kookolo, era zikula mangu nnyo.

Ebizimba by’ensawo y’omubisi gw’enjuki oba Ebizimba by’omu nnyindo (Endodermal Sinus Tumors).

Ensigo zino zirimu obutoffaali obufaanana ddala obutoffaali obuli mu nkwaso ekula.Bino biba bya bulabe era bisobola okusaasaana amangu ennyo mu nnywanto n’ebitundu ebirala. Ebizimba by’ensawo y’omubisi gw’enjuki kye kika ky’ekizimba ky’obutoffaali bw’obuwuka obuleeta kookolo ekisinga okubeera mu baana abato.

Obulwadde bwa Germinoma

Kino nakyo kika kya kizimba kya kookolo. Kiyinza okukula mu nkwaso oba mu nseke. Wabula businga kusangibwa mu bwongo n’omugongo (central nervous system). Bwe kikula mu nkwaso, kiyitibwa dysgerminoma , ate bwe kikula mu nseke, kiyitibwa seminoma .

Kookolo w’obutoffaali bw’embuto

Kino kizimba ekitatera kubaawo, ekizimba obutoffaali bw’obuwuka obuleeta kookolo. Oluusi kiyinza okubaawo kyokka, naye emirundi mingi kirabibwa nga kigatta wamu n’ebika by’ebizimba ebirala, ne kikola ekizimba ky’obutoffaali bw’obuwuka obutabuliddwamu .

Obulwadde bwa Polyembryoma

Ebizimba bino birimu ebitundu ebiringa embuto. Kino nakyo kika kya kizimba kya kookolo ekitali kya bulijjo nnyo, ekikula amangu. Ebiseera ebisinga, ebizimba bino bitondebwa nga bigattiddwa wamu n’ebizimba ebirala eby’obutoffaali bw’obuwuka.

Obulwadde bwa kookolo w’amayinja

Ebizimba bino bikolebwa okuva mu butoffaali obukola enseke ng’oli lubuto. Nga bw’oyinza okuba ng’okimanyi nti enseke kye kitundu ekiyamba maama n’omwana okuwanyisiganya ebiriisa. Choriocarcinoma era kizimba ekitali kya bulijjo, ekizimba obutoffaali bw’obuwuka obuleeta kookolo. Wadde busobola okukula mu nkwaso oba ensigo, businga kukula mu nnabaana. Eky’enjawulo ku kyo kwe kuba nti kisobola okusaasaana mu mwana ali mu lubuto ne maama.

Ebizimba by’obutoffaali bw’obuwuka obutabuddwa

Bino bizimba ebitondebwawo ng’ebika bibiri oba okusingawo eby’ebizimba by’obutoffaali bw’obuwuka obuleeta kookolo bikwatagana. Mu butuufu ebizimba by’obutoffaali bw’obuwuka bingi bitabuddwa wamu bwe bityo.

Njawulo ki eriwo wakati w’ebizimba bya seminoma n’ebitali bya seminoma?

Ebizimba by’obutoffaali bw’obuwuka mu basajja naddala kookolo w’ensigo byawulwamu ebika bibiri: seminomas ne non-seminomas . Zombi bizimba bya kookolo.

• Seminomas: Zino zitera okukula ne zisaasaana mpola okusinga ezitali za seminomas.
• Non-seminomas: Zino zikula ne zisaasaana mangu okusinga seminomas. Ebizimba by’ensawo y’enkwaso, kookolo w’obutoffaali bw’embuto, kookolo w’omubiri (choriocarcinomas), ne teratomas biri mu kiti kino eky’ebitali bya seminomas.

Ebizimba bino eby’obutoffaali bw’obuwuka bitera bitya?

Ebizimba by’obutoffaali bw’obuwuka mu butuufu tebitera kubaawo mu baana abato. Zikola ebitundu nga 3.5% ku kookolo yenna mu baana. Kyokka, zisinga kulabibwa mu bavubuka n’abavubuka abakulu. Zikola ebitundu nga 13.9% ku kookolo yenna mu bantu abali wakati w’emyaka 15 ne 19.

Ani asinga okukosebwa embeera eno?

Wadde omuntu yenna asobola okufuna ebizimba by’obutoffaali bw’obuwuka, .Abaana abawere, abato, abatiini, n’abato abakulu be basinga okukwatibwa obulwadde buno. Obunene bw’obuzibu buno bwawukana okusinziira ku myaka. Okugeza, zitera okubaawo okuva mu buwere okutuuka ku myaka nga 4, olwo ne zikendeera katono, ate ne ziddamu okweyongera mu myaka gy’obuvubuka.

• Ebizimba by’obutoffaali bw’enkwaso: Bino bisinga kubeera mu bawala abali wakati w’emyaka 10 ne 14. Kyokka era bisobola okukula mu bantu abali mu myaka 20 ne 30. Mature teratoma (ebiseera ebisinga si kookolo) kye kika ky’ekizimba ky’obutoffaali bw’obuwuka ekisinga okuzuulibwa.
• Ebizimba by’obutoffaali bw’ensigo: Ekika kino kikola ebitundu 75% ku kookolo w’ensigo mu baana, ne 90% ku kookolo yenna ow’ensigo. Zisinga kubeera mu baana abali wansi w’emyaka 4 n’abasajja abali wakati w’emyaka 15 ne 35.
• Ebizimba by’obutoffaali bw’obuwuka obuyitibwa Extragonadal germ cell tumors: Ebizimba bino bikola ebitundu 40% ku 50% ku bizimba byonna eby’obutoffaali bw’obuwuka ebizuulibwa mu baana abali wansi w’emyaka 4. Kyokka era zisobola okubeerawo mu baana abato n’abavubuka. Mu baana abawere n’abato, zisinga kusangibwa mu bitundu by’omubiri ebiyitibwa sacrum oba coccyx. Mu bavubuka n’abavubuka abakulu, zisinga kusangibwa mu bitundu by’omubiri ebiyitibwa mediastinum.
• Ebizimba by’obutoffaali bw’obuwuka mu bwongo: Wadde bino tebitera kubaawo, bisinga kuzuulibwa mu bantu abali wakati w’emyaka 11 ne 30.

Bubonero ki obulaga ekizimba ky’obutoffaali bw’obuwuka?

Obubonero bw’ekizimba kino bwawukana okusinziira ku bunene bw’ekizimba n’ekifo we kiri ku mubiri.

Obubonero bw’ebizimba by’enkwaso

Ebizimba by’obutoffaali bw’obuwuka ebikula mu nkwaso tebitera kuleeta bubonero. Okugeza, teratoma ekuze eyinza obutaleeta bubonero bwonna okutuusa ng’enene ekimala okuleeta obulumi mu lubuto. Zitera okuzuulibwa nga bakeberebwa ‘ultrasound scan’ okunoonya ekivaako obulumi mu lubuto olwa wansi.

Obubonero buyinza okuba bwe buti:

• Obutabeera bulungi oba obulumi mu lubuto olwa wansi.
• Okuwulira ekizimba ekiruma mu nkwaso.
• Okuzimba, okuzimba.
• Obulumi mu lubuto (nga appendicitis ).
• Okuvaamu omusaayi mu bukyala obutasalako.
• Ekikeeto.

Obubonero bw’okuzimba ensigo

Obubonero bw’ebizimba by’obutoffaali bw’obuwuka obukula mu nsigo bufaananako n’obwa kookolo w’ensigo.

Engeri zino ze zino wammanga:

• Ekizimba ekikaluba era ekigumu mu nsigo ekigenda kikula mpolampola (kiyinza okuluma oba obutalumizibwa).
• Okuwulira obulumi oba okuzitowa mu nseke.
• Obulumi mu lubuto oba okulumwa ekisambi.
• Enkula y’ensigo etali ya bulijjo.
• Obulumi bw’omugongo.

Obubonero bw’ebizimba ebibeera mu bifo ebirala (extragonadal) .

Ekizimba mu bisambi by’omwana wo oba wakati mu kifuba kyeBwe wabaawo, kiyinza okuba nga kya teratoma. Obubonero obulala bwawukana okusinziira ku kifo ekizimba we kiri.

• Okukaluubirirwa okussa (bwe kiba nga kikwatagana n’amawuggwe).
• Obunafu mu magulu (bwe kiba mu mugongo ogwa wansi).
• Okukaluubirirwa okufulumya omusulo n’okufulumya omusulo (ssinga obuzibu buba bwekuusa ku kifuba).
• Omwana alina okuzimba n’obulumi obw’amaanyi oba obutono mu lubuto.

Ebizimba ebimu eby’obutoffaali bw’obuwuka bifulumya obusimu obuzaala. Kino kiyinza okuvaako abaana okulaga obubonero bw’okutuuka mu myaka gy’obuvubuka nga bukyali oba okukula mu by’okwegatta mu ngeri etaali ya bulijjo. Abawala bayinza okufuna amabeere, enviiri z’omu kifuba n’okugenda mu nsonga nga bukyali. Abalenzi bayinza okufuna amabeere (gynecomastia).

Kiki ekivaako ebizimba bino eby’obutoffaali bw’obuwuka?

Mu budde obwabulijjo, obutoffaali buno obw’obuwuka butondebwa ng’embuto y’omuntu ekula. Olwo obutoffaali buno ne busenguka ne bugenda mu nkwaso oba ensigo z’embuto, gye bufuuka obutoffaali bw’amagi oba obutoffaali bw’ensigo.

Naye, mu bizimba by’obutoffaali bw’obuwuka, obutoffaali buno tebukula mu bujjuvu ne bufuuka magi oba ensigo. Mu kifo ky’ekyo, obutoffaali buno obw’obuwuka bweyawukana mu ngeri etaali ya bulijjo ne bukola ebizimba mu nkwaso oba mu nsigo. Mu ‘ebizimba eby’ebweru w’enjuyi’ bye twayogeddeko emabegako, obutoffaali buno obw’obuwuka bugenda mu bifo ebyewuunyisa mu mubiri - ebifo ng’ekifuba, obwongo, olubuto, wansi w’omugongo, enkwaso - ne bukola ebizimba eyo.

Mu butuufu, abanoonyereza n’okutuusa kati tebannaba kuzuula bulungi nsonga lwaki obutoffaali buno obw’obuwuka bweyisa bwe butyo.

Biki ebiyinza okuvaako akabi?

Oyinza okulwala ekizimba ky’obutoffaali bw’obuwuka singa omuntu mu maka go abadde alina ekizimba kino emabegako, oba ng’olina embeera z’obujjanjabi ezimu.

Zino ze mbeera nga zino:

• Okubeera n’ensigo ezitajjanjabiddwa, ezitakka ( cryptorchidism ).
• Embeera eyitibwa Turner syndrome .
• Embeera eyitibwa Klinefelter syndrome .

Zino mbeera za buzaale oba enkulaakulana abasawo ze bazuula.

Ebizimba by’obutoffaali bw’obuwuka bizuulibwa bitya? (Okuzuula obulwadde)

Omusawo ajja kusooka kwekebejja omubiri akubuuze ku bubonero bwo. Oluvannyuma, bayinza okukola ekimu oba ebisingawo ku bino wammanga okuzuula oba olina ekizimba ky’obutoffaali bw’obuwuka:

• CT scan: Kino kizingiramu okukuba ebifaananyi bingi ebya X-ray eby’omunda mu mubiri gwo n’okozesa kompyuta okukola ekifaananyi eky’ebitundu bisatu (`3D`) eky’amagumba n’ebitundu ebigonvu. CT scan y’ekifuba, olubuto oba ekisambi esobola okuyamba okuzuula ekizimba.
• MRI: Kino kikozesa magineeti n’amayengo ga leediyo okukola ekifaananyi kya kompyuta eky’amagumba n’ebitundu ebigonvu eby’omubiri. Okufaananako ne CT scan, MRI esobola okulaga ekifo ekizimba we kiri.
• Okukebera eddoboozi ery’omwanguka:Kino kikozesa amaloboozi okukola ebifaananyi eby’omunda mu mubiri. Ultrasound eraga obungi bw’ekizimba bwe bukalu n’obungi bw’amazzi (`cystic`). Amawulire gano gayamba okuzuula oba ekizimba kizimba kya butoffaali bwa buwuka oba mazzi gokka (`cyst`).
• PET scan: Kino kikozesa eddagala ery’enjawulo (a `tracer`) okuzuula ebitundu by’obutoffaali bwa kookolo mu mubiri. PET scan nayo esobola okulaba oba kookolo asaasaanye.
• Okukebera amagumba: Kino kizingiramu okufuyira langi ey’enjawulo mu mubiri, n’agisobozesa okuyingira mu magumba, n’oluvannyuma n’akuba ebifaananyi bya X-ray. Langi eno eyamba okulaga ebitali bya bulijjo era esobola okuyamba okuzuula oba ekizimba kisaasaanidde mu magumba.
• Okukebera omusaayi: Omusawo ayinza okukwata omusaayi okukebera emiwendo gy’enziyiza, puloteyina oba obusimu obumu mu musaayi gwo. Ebintu ebingi nga human chorionic gonadotropin (hCG) , alpha-fetoprotein (AFP) , ne lactate dehydrogenase biyinza okuba akabonero k’ebika ebimu eby’ebizimba by’obutoffaali bw’obuwuka.
• Biopsy: Kino kizingiramu okuggya akatundu akatono mu kizimba n’akasindika mu laabu okukeberebwa. Omukugu mu by’endwadde , omusawo omukugu mu kwekenneenya ebitundu by’omubiri, ajja kwekenneenya sampuli eno ng’akozesa microscope okuzuula oba kizimba kya butoffaali bwa buwuka.

Ekikulu: Singa ekizimba kyo kiyinza okuba nga kya kookolo, omusawo ayinza okusalawo okuggyamu ekitundu ekyo kyonna. Okugeza, enkola eya bulijjo ey’okuzuula kookolo w’ensigo kwe kuggyamu ensigo yonna ( radical inguinal orchiectomy ). Okuggyamu ensigo kisobozesa omusawo wo okwekenneenya ebitundu by’omubiri n’okulongoosa ng’obujjanjabi.

Ebizimba by’obutoffaali bw’obuwuka bijjanjabwa bitya?

Waliwo engeri eziwerako ez’obujjanjabi. Omusawo wo ajja kusalawo obujjanjabi obusinga obulungi okusinziira ku kika, obunene, ekifo ekizimba we kiri, n’obulamu bwo okutwalira awamu.

• Okulongoosa: Okulongoosa bwe bujjanjabi obusinga ku bizimba by’obutoffaali bw’obuwuka. Mu mbeera y’ebizimba by’enkwaso, ekizimba kyokka kye kiyinza okuggyibwamu ( ovarian cystectomy ), oba enkwaso yonna n’enkwaso biyinza okuggyibwamu ( salpingo-oophorectomy ). Mu mbeera ya kookolo w’ensigo, enseke ezirimu ekizimba ziggyibwamu.
• Chemotherapy: Kino kizingiramu okukuwa eddagala eritta obutoffaali bwa kookolo oba okubulemesa okwawukana. Singa omusawo wo tasobola kuggyawo kizimba kino awatali bulabe, oba nga kisaasaana mu bitundu by’omubiri ebirala, oyinza okuweebwa eddagala eriweweeza ku bulwadde. Oluvannyuma lw’okulongoosebwa, era baweebwa eddagala eriweweeza ku bulwadde bwa kookolo okutta obutoffaali bwa kookolo bwonna obuyinza okulekebwa emabega, ne bwe buba nga tebuzuuliddwa ku sikaani. Chemotherapy ekozesebwa ku bika by’ebizimba by’obutoffaali bw’obuwuka ebisinga obungi.Enkola y’obujjanjabi ekola obulungi ennyo.
• Obujjanjabi bw’amasannyalaze: Kino kizingiramu okukozesa X-rays ez’amaanyi amangi okusaanyaawo obutoffaali bwa kookolo. Ebika ebimu eby’ebizimba by’obutoffaali bw’obuwuka bikola bulungi ku bujjanjabi bw’amasannyalaze.

Ekizimba ky’obutoffaali bw’obuwuka kisobola okuwona ddala?

Enteebereza oba essuubi ly’okuwona, eri ebizimba ebisinga obungi eby’obutoffaali bw’obuwuka nnungi nnyo. Obulwadde buno butera okuwona singa ekizimba kiggyibwawo ddala. Okugeza kookolo w’ensigo alina ebitundu 95% eby’okuwangaala oluvannyuma lw’okujjanjabibwa. Ebizimba by’obutoffaali bw’obuwuka bw’enkwaso biwangaala ebitundu 93%. Ebizimba by’obutoffaali bw’obuwuka mu baana biwona wakati wa 82% ne 90%.

Kyokka, ebivaamu bino bisinziira ku bintu ebiwerako ebikukwatako. Mu bino mulimu:

• emyaka gyo.
• Ekika ky’ekizimba ky’obutoffaali bw’obuwuka.
• Ekifo n’obunene bw’ekizimba.
• Ebanga kookolo ly’asaasaanidde.
• Enkola y’ekizimba ku bujjanjabi.

N’olwekyo, kikulu nnyo okwogera n’omusawo wo ku ngeri okuzuulibwa kwo gye kunaakwata ku bivuddemu.

Ebibuuzo ebikulu by’olina okubuuza omusawo wo

Osobola okubuuza ebibuuzo bino okusobola okutegeera obulungi engeri gy’ozuddemu:

• Ekizimba kyange kirimu kookolo (malignant)?
• Ekizimba kyange kikula mangu ki (aggressive)?
• Kookolo asaasaana?
• Bujjanjabi ki bw’oteesa?
• Biki ebiyinza okuva mu bujjanjabi?
• Biki ebiyinza okuvaamu ebikwatagana ne buli ngeri y’obujjanjabi?
• Bikebere ki bye nneetaaga okukola okulondoola obulungi bw’obujjanjabi?
• Mirundi emeka gye nja okwetaaga okujja ku ssaawa z‟okugoberera okulondoola ekizimba kyange/engeri gye nddamu obujjanjabi?

N’ekisembayo, ebintu by’olina okujjukira (Obubaka bw’okutwala awaka) .

Ekizimba ky’obutoffaali bw’obuwuka kye kizimba ekikula okuva mu butoffaali obuzaala. Omusawo asobola okukunnyonnyola engeri okuzuula kuno gye kunaakukwatamu oba omwana wo. Ebizimba by’obutoffaali bw’obuwuka bizibu katono. Obubonero bwo n’engeri gy’ogenda okulagulamu bisinziira ku bintu bingi, byonna omusawo wo by’ajja okukubaganyaako ebirowoozo naawe.

Amawulire amalungi gali nti ebizimba by’obutoffaali bw’obuwuka ebisinga bikola bulungi ku bujjanjabi. Nga bwe kiri ku kizimba kyonna (naddala ebizimba bya kookolo), gy’okoma okuzuula amangu n’otandika okujjanjabwa, gy’okoma okuba ebirungi. N’olwekyo, bw’oba ​​olina ekizimba ekitali kya bulijjo, okuzimba oba okulumwa, kiba kya magezi okunoonya amagezi g’abasawo mu kifo ky’okukibuusa amaaso.

` Ebizimba by’obutoffaali bw’obuwuka, kookolo, teratoma, ekizimba ky’ensawo y’enkwaso, germinoma, kookolo w’enkwaso, kookolo w’ensigo