Olina obusimu obuyitibwa prolactin bungi mu mubiri gwo? Ka twogere ku hyperprolactinemia!

Wali weebuuzizzaako ebintu ebiyinza okubaawo ng’olina enkyukakyuka entonotono mu bumu ku busimu obuli mu mubiri gwo? Eyo y’embeera gye tugenda okwogerako leero, eyitibwa hyperprolactinemia. Mu ngeri ennyangu, kino omusaayi gwo bwe guba n’obusimu obuyitibwa prolactin obuyitiridde. Obusimu buno businga kuvunaanyizibwa ku nkula y’amabeere n’okukola amata. Embeera eno si ya bulabe eri obulamu, naye oluusi eyinza okukuleetera obuzibu ng’obutazaala n’okutaataaganya obusobozi bwo okubeera mu bulamu obwa bulijjo. Naye ekirungi nti waliwo obujjanjabi obugijjanjaba.

Embeera eno ya bulijjo etya?

Mu butuufu, embeera eno eyitibwa hyperprolactinemia si ya bulijjo nnyo. Kikwata abantu abatakka wansi wa 1% ku bantu bonna. Wabula abakyala batera okufuna embeera eno okusinga abasajja.

Bubonero ki obulaga kino?

Kijjukire nti abantu abamu bayinza okuba n’obulwadde bwa hyperprolactinemia naye nga tebalaga bubonero bwonna, oba obubonero buyinza okuba nga butono nnyo. Wabula waliwo obubonero obutonotono obutera okulabika ng’olina embeera eno, awatali kufaayo ku muntu oyo.

Obubonero obwa bulijjo obukwata buli muntu

Bino bisobola okubaawo mu muntu yenna, awatali kufaayo ku kikula ki:

• Okukaluubirirwa okuzaala (obutazaala) : Kino kye kizibu ekikulu.
• Obwagazi obutono : Kino kitegeeza nti okwagala okwegatta kukendeera.
• Okukendeera kw’amagumba (osteopenia) : Kino kiyinza okuvaako amagumba okunafuwa okumala ekiseera.
• Amata agafuluma mu nfuli ng’oli lubuto oba ng’oyonsa (`galactorrhea`) : Kino kiyinza okuwulikika ng’ekyewuunyisa katono, naye era kabonero.

Engeri ezikwata ku bakyala

Ku bakyala, ng’oggyeeko obubonero buno obutera okulabika, obubonero obulala obuwerako obw’enjawulo buyinza okubaawo:

• Enkyukakyuka mu nnaku z’omu nsonga ezitakwatagana na kuggwaamu nsonga (okukomya okugenda mu nsonga buli mwezi) : Kino kitegeeza nti okugenda mu nsonga kufuuka okutali kwa bulijjo oba kukoma ddala. Oyinza obutagenda mu nsonga okumala emyezi.
• Obulumi nga beegatta olw’obukyala okukala : Kino nakyo kintu ekireetera abakyala bangi obutabeera bulungi.

Engeri ezikwata ku basajja

Embeera eno ekosa abasajja mu ngeri ya njawulo. Wano waliwo obubonero obutera okulabika bwe bayinza okufuna:

• Obuzibu bw’okusituka (ED) : Kino kitegeeza obuzibu mu kusituka.
• Okukendeera kw’obusimu obuyitibwa testosterone : Buno busimu bukulu mu mubiri gw’omusajja.
• Okugaziya amabeere (`gynecomastia`) : Okukula kw'amabeere g'omusajja okufaananako n'ag'omukazi.

Lwaki kino kigenda mu maaso? Ensonga ze ziruwa?

Okay, kati katutunuulire lwaki prolactin levels zeeyongera bweziti. Wandibaawo ensonga eziwerako.

• Obulwadde bwa Prolactinoma: Eno y'ensonga enkulu. `(Prolactinoma)` kizimba ekitali kya kookolo (benign) (`adenoma`) ekikula mu `(Pituitary gland)` mu bwongo bwo. Ekizimba kino kireetera obusimu obuyitibwa prolactin okukola ekisusse.
• Ebizimba ebirala ebiyitibwa pituitary tumors : Ng’oggyeeko prolactinoma, ebizimba ebirala ebinene mu pituitary gland oba okumpi nabyo bisobola okuleeta prolactin okubeera waggulu. Kino kibaawo kubanga ekizimba kiziyiza okufulumya eddagala eriyitibwa dopamine mu nseke y’omubiri (pituitary gland). Dopamine busimu obufuga okukola ekirungo kya prolactin.
• Eddagala erimu : Eddagala eriyitibwa dopamine likendeeza ku kukola prolactin. Kale, eddagala lyonna erikosa okukola dopamine liyinza okwongera ku miwendo gyo egya prolactin. Ezimu ku ddagala lino mulimu:
• Empeke z’okuziyiza okuzaala
• Eddagala erimu eriwonya endwadde z’obwongo, nga Risperidone ne Haloperidol
• Eddagala eriwonya puleesa, nga methyldopa ne verapamil
• Eddagala ly’okulumwa omutima n’obulwadde bw’okuzimba olubuto n’omumwa gwa nnabaana (GERD) (e.g. H2 antihistamines) .
• Eddagala eriweweeza ku kweraliikirira, gamba ng’eddagala eriweweeza ku kweraliikirira erya tricyclic ne SSRIs
• Eddagala eriwonya obubonero bw’okuggwaamu amaanyi mu nsonga, gamba ng’obujjanjabi bwa estrogen
• Eddagala eriweweeza ku kuziyira n’okusiiyibwa (antiemetics) .
• Eddagala eriweweeza ku bulumi eririmu eddagala lya opioids

Ekikulu : Mazima ddala olina okwogera n'omusawo wo nga tonnayimiriza ddagala lyonna ly'omira. Ebiseera ebisinga emiwendo gya Prolactin gidda mu mbeera eya bulijjo mu nnaku ssatu oba nnya ng’omaze okuyimiriza eddagala lino.

• Embeera endala ez’obulamu : Ne bwe kiba nga tolina bulwadde bwa prolactinoma, embeera endala ezimu ziyinza okuvaako emiwendo gya prolactin okulinnya. Embeera ng’ezo mulimu:
• Obuvune ku bbugwe w’ekifuba (e.g., okumenya embiriizi) .
• Obulwadde bw’ekibumba obutawona
• Obulwadde bw’ekibumba obutawona
• Obulwadde bwa Cushing
• Obulwadde bwa Hypothyroidism (thyroid obutakola bulungi) .
• Herpes zoster (shingles), naddala singa ebizimba/amabala galabika ku kifuba
• Obulwadde bw’enkwaso eziyitibwa polycystic ovary syndrome (PCOS) .

Watya singa tosobola kufuna nsonga?

Oluusi abasawo tebasobola kufuna kivaako kino. Mu mbeera eyo, kiyitibwa "idiopathic hyperprolactinemia." Kino kitera okuggwaawo nga tewali bujjanjabi mu myezi mitono.

Biki ebiyinza okuvaako akabi?

Ensonga yokka emanyiddwa ey’obulabe eri obulwadde bwa hyperprolactinemia y’embeera eyitibwa Multiple endocrine neoplasia (MEN) type 1 (MEN1). MEN1 mbeera ya nsikirano eyinza okuvaako okukula kw’obulwadde bwa prolactinoma.

Singa omuntu mu maka go (muganda, mwannyina, omuzadde) aba ne `MEN1`, kirungi okukeberebwa obuzaale. Kino kiyinza okuyamba okuzuula `(Prolactinoma)` nga bukyali.

Kino okitegeera otya ddala?

Bw’oba ​​olina obubonero buno, omusawo ky’asooka okukola kwe kukebera omusaayi gwa prolactin (PRL).

Singa ebyavaamu bikakasa nti olina obulwadde bwa hyperprolactinemia, ekiddako kwe kuzuula ekivaako. Omusawo ayinza okulagira okukeberebwa omusaayi ebirala n’okukeberebwa ebifaananyi (nga MRI scan).

Obujjanjabi bwe buruwa?

Obujjanjabi businziira ku kivaako. Singa eddagala lya prolactin liri waggulu naye ng’obubonero bwo buba butono, oyinza obuteetaaga bujjanjabi.

Obujjanjabi bw’obulwadde bwa prolactinoma

Kino kye kisinga okuvaako. Kale waliwo engeri eziwerako ez’okubujjanjaba:

• Eddagala : Eddagala eriziyiza dopamine lifuga omuwendo gwa prolactin gwo. Eddagala lino era likola nnyo mu kukendeeza ebizimba bya prolactinoma. Eno y’obujjanjabi obusinga okukozesebwa ku bulwadde bwa prolactinoma.
• Okulongoosa : Singa prolactinoma tekendeera na ddagala, kiyinza okwetaagisa okulongoosebwa okugiggyamu.
• Radiation therapy : Eno y’engeri ey’okusatu etatera kukozesebwa. Kikozesebwa ng’enkola endala tezifunye buwanguzi.

Bwe kiba nga kiva ku ddagala...

Singa kizuulibwa nti omuwendo gwa prolactin gwo guli waggulu olw’eddagala ly’omira, omusawo ajja kukuwa eddagala ery’enjawulo eritajja kubaako kinene kye likola ku muwendo gwa prolactin.

Emikisa ki egy’okuwona?

Obulwadde bwa Hyperprolactinemia butera okutereera kubanga ekivaako obulwadde buno bujjanjabwa bulungi.

Wadde kino tekiba kya bulabe eri obulamu, kiyinza okuleeta obuzibu ng’obutazaala n’okugenda mu nsonga ezitali za bulijjo, n’olwekyo kikulu nnyo okunoonya obujjanjabi bw’oba ​​olina embeera eno.

Ebibuuzo by’olina okubuuza omusawo wo

Bw’oba ​​olina obulwadde bwa hyperprolactinemia, kiyinza okukuyamba okubuuza omusawo wo ebibuuzo bino:

• Lwaki kino kyantuukako?
• Bigezo ki bye nneetaaga okukola?
• Bujjanjabi ki bwe nnina?
• Birungi ki n’ebibi ebiri mu buli bujjanjabi?
• Ekizibu kyange eky’obutazaala kinagonjoolwa oluvannyuma lw’obujjanjabi buno?

Obulwadde bwa Hyperprolactinemia buyinza okukosa omutindo gw’obulamu bwo n’okutaataaganya obusobozi bwo obw’okuzaala. Naye ekisinga obulungi nti esobola okujjanjabibwa obulungi. Bw’oba ​​olina obubonero bw’embeera eno, kakasa nti ogenda ew’omusawo. Olwo okukebera omusaayi okwangu kuyinza okukebera omuwendo gwa prolactin gwo.

N’ekisembayo, kiki ky’olina okujjukira

Laba, hyperprolactinemia kwe kweyongera kw’obusimu bwa prolactin mu mubiri gwaffe. Kino kiyinza okuleeta obuzibu ng’okukaluubirirwa okufuna embuto, okukendeeza obwagazi, obutabeera bulungi mu nsonga mu bakyala, n’obutasobola kwegatta mu basajja .

Ekisinga okuvaako kino kye kizimba ekiyitibwa ``Prolactinoma`` ekikula mu nseke y’omubiri (pituitary gland). Embeera eno era esobola okuva ku ddagala erimu n'endwadde endala .

Tofaayo! Waliwo obujjanjabi obulungi ku kino. Bw’oba ​​olina obubonero buno, kirungi okugenda ew’omusawo amangu ddala nga bwe kisoboka. Olwo osobola okuzuula ekituufu ekivaako n’otandika obujjanjabi obusinga okukukwatako. Kikulu nnyo okufaayo ku bulamu bwo.

` Prolactin, Hyperprolactinemia, Enseke z’omu lubuto, Obutakwatagana mu busimu, Obutazaala, Galactorrhea, Prolactinoma