Bwoba oli maama ali lubuto, maama ayonsa, oba omuntu asuubira omwana, osanga owulidde erinnya "prolactin". Kino kirungo kikulu nnyo mu mubiri gwaffe naddala mu bakyala, nga kino kyenyigira mu bintu bingi, gamba ng’okuzaala n’okukola amata g’amabeere. Kale katukyogereko mu ngeri ennyangu era mu mpisa leero.
Mu ngeri ennyangu, prolactin kye ki?
Lowooza ku mubiri gwaffe ng’ekkolero eddene nga lirimu abakugu ku buli mulimu. Obusimu bwe bubaka obutambuza obubaka okukuuma ekkolero lino nga litambula bulungi. Prolactin , era emanyiddwa nga Lactotropin oba PRL, y’omu ku babaka abakulu ng’abo.
Wadde ng’obusimu buno bwenyigira mu bikumi n’ebikumi by’emirimu mu mubiri gwaffe, bulina emirimu ebiri emikulu:
1. Okuyamba mu kukola amata g’amabeere (Lactation): Ensonga enkulu lwaki maama asobola okukola amata eri omwana we ye hormone prolactin.
2. Ayamba mu kukula kw’amabeere: Obusimu buno buvunaanyizibwa ku kukulaakulanya endwadde ezikola amata mu mabeere naddala ng’oli lubuto, n’okugateekateeka okuyonsa.
Mu ngeri ennyangu, obusimu buno obwa prolactin bwe bulagira omubiri gwaffe okukola ekirabo ekisinga okuba eky'omuwendo ekiyitibwa "amata g'amabeere" ekyetaagisa okumala enjala y'omwana ng'amaze okuzaala omwana.
Obusimu buno obuyitibwa Prolactin buva wa? Kikola kitya?
Wansi w’obwongo bwaffe, waliwo akatundu akatono naye nga ka maanyi nnyo nga kaweza obunene bw’akawuka akatono akayitibwa Pituitary Gland . Kiba nga "ekisenge ekifuga" enkola y'obusimu bw'omubiri gwaffe. Mu kisenge kino eky’okufuga mwe muva prolactin ekolebwa mu bungi n’efulumizibwa mu musaayi.
Naye kino tekikoma ku kubaawo. Waliwo ba master babiri abafuga enseke y’omubiri (pituitary gland), nga bagigamba ekole prolactin ate nga bagigamba ekomye okugikola.
- Dopamine: Kino kirungo kya busimu mu bwongo bwaffe. Dopamine ekola nga ekendeeza ku kukola ekirungo kya prolactin. Kwe kugamba, dopamine ekuuma prolactin obutayongera nnyo.
- Estrogen: Buno busimu bukulu mu mukyala. Estrogen ayamba okwongera okukola prolactin.
Estrogen bwe yeeyongera ng’oli lubuto, n’okukola prolactin kweyongera. Kino kireetera endwadde ezikola amata (mammary alveoli) mu mabeere okukula ne ziteekateeka okuvaamu amata g’omwana.
Ekyewuunyisa ddala nti omwana bw'amala okuzaalibwa, omwana bw'anuuna ebbeere lya maama, obubaka obwo bugenda butereevu ku bwongo ne bugamba enseke y'omubiri "okukola prolactin omungi." Prolactin bwe yeeyongera, amata mangi gavaamu. Kino tukiyita ‘positive feedback loop’.Kwe kugamba, enkola bw’emala okutandika, eyongera okusitula enkola eyo.
Lwaki emiwendo gya prolactin gikyuka mangu?
Ebirungo bya Prolactin si bye bimu bulijjo. Oluusi zeeyongera mu butonde, ate oluusi zeeyongera olw’obulwadde.
Embeera nga mu butonde emiwendo gya Prolactin gyeyongera
Ebintu bino bisobola okuvaako omuwendo gwa prolactin gwo okulinnya okumala akaseera, ekitegeeza nti okumala akaseera katono. Kino kyabulijjo era tewali kweraliikirira.
- Situleesi mu mubiri: Bw’owulira obulumi obw’amaanyi.
- Dduyiro: Oluvannyuma lw’okukola dduyiro omulungi.
- Okulya: Oluvannyuma lw’okulya.
- Okwegatta: Oluvannyuma lw’ekikolwa ky’okwegatta.
- Okusitula amabeere: Singa amabeere gasikirizibwa ebweru w’okuyonsa.
- Obuvune mu kifuba: Singa wabaawo akabenje oba obuvune bwonna mu kitundu ky’ekifuba.
- Okufuna embuto n’okuyonsa: Mu butonde ebirungo bya Prolactin biba bingi nnyo mu biseera bino.
Ebirungo bya prolactin ebingi mu ngeri etaali ya bulijjo (Hyperprolactinemia) .
Embeera z’obujjanjabi oba eddagala ezimu ziyinza okuvaako omuwendo gwa prolactin okusigala nga guli waggulu mu ngeri etaali ya bulijjo okumala ebbanga eddene. Embeera eno mu by'obujjanjabi emanyiddwa nga hyperprolactinemia .
Ekisinga okuvaako kino y'embeera eyitibwa prolactinoma . Kino kizimba kitono, ekitali kya kookolo (ebiseera ebisinga) ekikula mu nseke y’omubiri (pituitary gland). Ekizimba kino kifulumya obusimu obuyitibwa prolactin mu ngeri eteetaagisa.
Omuwendo gwa prolactin bwe gufuuka waggulu mu ngeri etaali ya bulijjo, obubonero obuli wansi buyinza okulabika.
| Obubonero | Ani akosebwa n’okunnyonnyola okwangu |
|---|---|
| Obutazaala | Kiyinza okukwata abakyala n’abasajja. Prolactin bwe yeeyongera, etaataaganya okufulumya eggi n’okufulumya ensigo. |
| Enzirukanya ya buli mwezi etali ya bulijjo | Bukwata abakyala. Okugenda mu nsonga kuyinza obutabeera kwa bulijjo, okulwawo oba okukoma ddala. |
| Amata agafuluma mu mabeere (Galactorrhea) . | Embeera eno esobola okubaawo mu mukyala oba omusajja atali lubuto oba ayonsa. |
| Obwagazi bw’okwegatta okukendeera | Ya bulijjo eri abakyala n’abasajja. |
| Obuzibu bw’okusituka | Kikosa ekikula ky’omusajja. |
Omuwendo gwa prolactin guyinza okuba wansi mu ngeri etaali ya bulijjo?
Yee, kiyinza okubaawo. Naye tekitera kubaawo nnyo. Ebiseera ebisinga, okuggyako ng’oli lubuto oba ng’oyonsa, omuwendo gwa prolactin gwo guba mutono. Eyo mbeera nnungi.
Kale, akabonero kokka akalaga nti emiwendo gya prolactin giri wansi mu ngeri etaali ya bulijjo kwe butakola mata g’amabeere oluvannyuma lw’okuzaala omwana .
Mu mbeera eno, ekivaako kiyinza okuba embeera eyitibwa hypopituitarism . Kino kitegeeza nti enseke z’omubiri (pituitary gland) tekola busimu bumu oba obusingawo obwetaagisa. Eno nayo mbeera ya bbula nnyo.
Naye era kino olina okukijjukira. Omuwendo gwa prolactin omutono si y’ensonga yokka lwaki maama ayinza okuba n’amata amatono. Wayinza okubaawo ensonga endala nnyingi ezikiviirako. N’olwekyo, bw’oba olina obuzibu mu kuyonsa, kirungi okulaba omukugu oba omukugu mu kubuulirira ku by’okuyonsa ku nsonga eno.
Opima otya emiwendo gya Prolactin gyo?
Kino kyangu nnyo. Omusawo asobola okulagira okukeberebwa omusaayi (PRL test) okukebera omuwendo gwa prolactin mu musaayi gwo. Kino kiringa okukebera omusaayi buli kiseera. Bw’oba olina obubonero obwogeddwako waggulu n’oteebereza nti endwadde yo ey’omu lubuto (pituitary gland) ekola bulungi, omusawo ajja kulagira okukeberebwa kuno.
Emiwendo gya prolactin egya bulijjo gye giruwa?
Omulongooti wansi gulaga omuwendo ogwa bulijjo ogw’emiwendo gya prolactin mu muntu omulamu obulungi. Wabula emiwendo gino giyinza okwawukana katono okuva ku laabu okudda ku ndala. N'olwekyo, kikulu okukebera ekitundu "Normal Range" mu lipoota yo.
| Olubu | Omuwendo ogwa bulijjo (ng/mL) . |
|---|---|
| Abasajja | Ebitakka wansi wa 20 ng/mL |
| Abakyala abatali lubuto n’abatayonsa | Ebitakka wansi wa 25 ng/mL |
| Abakyala ab’embuto oba abayonsa | Wakati wa 80 ne 400 ng/mL |
Bw’oba olina ekikweraliikiriza ku bivudde mu kunoonyereza kwo, tolwawo kwogera n’omusawo wo ku nsonga eno.
Ddi lw’osaanidde okulaba omusawo ku ddagala lya prolactin?
Bw’oba olowooza nti olina obubonero bwonna obw’omuwendo gwa prolactin omungi gwe twayogeddeko waggulu (nga okugenda mu nsonga ezitali za bulijjo, obutazaala, n’okufulumya amazzi ng’amata okuva mu mabeere go), laba omusawo wo mangu . Asobola okudduka okukeberebwa, okuzuula ekivaako, n’okumuwa obujjanjabi bwe kiba kyetaagisa.
Bw’oba oli maama ayonsa era ng’olina ekizibu ky’amata agatali gamala, nakyo funa abasawo amagezi ku nsonga eyo.
Prolactin hormone eyeetaagibwa ennyo mu kufuna embuto n’okuyonsa. Naye okuggyako ekyo, tetukirowoozaako nnyo okutuusa ng’obubonero obutali bwa bulijjo bulabika. Kale beera mwegendereza enkyukakyuka mu mubiri gwo. Bw’oba olina ekikweraliikiriza, funa amagezi mu basawo.
Obubaka Obutwala Awaka
- Prolactin busimu obusinga kwetaagisa mu kukola amata g’amabeere n’okukula kw’amabeere.
- Obusimu buno bukolebwa ekitundu ekiyitibwa pituitary gland mu bwongo.
- Mu butonde omuwendo gwa prolactin gweyongera ng’oli lubuto n’okuyonsa.
- Omuwendo gwa prolactin omungi mu ngeri etaali ya bulijjo (Hyperprolactinemia) guyinza okuleeta obuzibu ng’obutazaala n’okugenda mu nsonga ezitali za bulijjo.
- Bw’oba olina obubonero nga buno, totya era weebuuze mangu omusawo akuwe amagezi.
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