Taksa chu hmelma a lo nih a, pancreas a beih chuan - Autoimmune Pancreatitis chungchang hi han sawi ila!

I taksa defence system, immune system hi ram venghimtu sipai ang a ni. He sipai hna chu pawn lam atanga lo chhuak hrik leh virus ang chi hmelma te hriatchhuah a, beih a, natna laka min chhanchhuah hi a ni. Mahse, he sipaite hian tlem tal kal sual a, kan ram ngeia mi tha te hi hmelma nia inngaia beih tan ta se eng ang chhiatna nge thleng ang tih han ngaihtuah teh? Chutiang chu Autoimmune Pancreatitis (AIP) an tih natnaah chuan a thleng thin. Hetah hian kan defense system ngei pawhin kan pancreas ngei pawh hi hmelmaah a ngai sual a, kan bei tan ta a ni.

A awlsam zawngin, Autoimmune Pancreatitis (AIP) hi eng nge ni?

Hei hi thil awm lo tak a ni. Kan sawi tawh ang khan kan immune system hian kan pancreas chu a bei a, chronic inflammation, a nih loh leh pancreatitis a thlen thin. Hun kal zelah he chhiatna hi a lo thlen meuh chuan harsatna lian tak tak a lo chhuak tan thin. Vawi tam tak chu chhiatna nasa tak a thlen hma chuan chhinchhiahna engmah kan hmu lo mai thei.

He natna hi hriat chian a harsa thei hle. Hei hi a chhan chu natna hmuh tur awm lo tak a nih vang a ni a, a lan chhuah dan chu a lang chiang lo va, scan-ah pawh natna dang, a bik takin pancreatic cancer angin a lang thei a ni. Hei hi mi tam tak tan chuan a hlauhawm thei hle. Mahse a tha ber chu i natna hmuhchhuah a nih hnuah leh enkawlna dik tak i tan hnuah chuan i dam thuai thei a ni .

Autoimmune Pancreatitis (AIP) hi chi hnih a awm a, chungte chu:

He natna hi chi hnih a awm a. Kan taksa an nghawng dan hi a danglam deuh hlek a. Eng nge an nih i han thlir teh ang.

Type 1 AIP chungchang tlem tal...

A awlsam zawngin, hei hi natna pawl lian zawk, IgG4-related diseases an tih zinga pakhat a ni. IgG4 hi kan taksain antibody a siam chi khat a ni. He natnaah hian IgG4 leh immune cells plasma cells an tih te chu an inzawm khawm a, pancreas tissue te chu an kal tlang a, inflammation leh scarring an siam thin.

Type 2 AIP chungchang tlem tal...

Hetiang chiah hian IgG4 level a sang lo. Tin, taksa peng dangte pawh a nghawng lo. Mahse, heng mite hian a chang chuan acute pancreatitis episode recurrent an nei thei a ni. Chu chu pancreas chu a inflamed nghal a, symptoms a lo lang a, chu chu ni engemaw zat hnuah a reh leh thin tihna a ni.

He natna lan chhuah dan engte nge ni?

Hun rei tak chhung chu a lan chhuahna awm lo mah se, a lan chhuah hmasak ber chu natna nei lo jaundice . Hei hi chhinchhiahna pawimawh tak a ni. Mi thenkhat chuan pum chunglam emaw, hnungzang emaw na an nei thei. Hei hi kan pancreas hi pum leh ruhro inkar a awm vang a ni.

Chu bakah, heng symptoms te hi i hmu thei bawk:

• Zun dum leh bawlhhlawh dum (fading to white) .
• Chau
• Indigestion (indigestion) a awm lo
• Chaw ei chakna hloh leh taksa rihna tlahniam
• Nausea leh luak chhuak

Engvangin nge he natna hi a lo awm? Risk factors te chu engte nge ni?

Dik tak chuan scientist te chuan heng autoimmune natna te hi engvangin nge an lo awm tih hi 100% in an la sawi chiang thei lo. Genes leh environmental factors pahnih inzawmkhawm a nih an ring . Entirnan, kan taksain natna khirh tak a neih chuan kan taksa hriselna (immune system) chu a do theih nan a thawk nasa lutuk thei a ni. A châng chuan, insual a zawh hnuah, system chuan a rilru hahdam dân chu a theihnghilh thei a, a cell-te chu a bei ṭan thei bawk.

Tin, autoimmune disease dang nei tawh chuan AIP a vei theihna a sang deuh bawk. Entir nan:

• Hashimoto natna (thyroid gland nena inzawm natna) .
• Ulcerative colitis (rilru lian tham natna) .
• Rheumatoid arthritis natna a ni
• Sjögren’s syndrome (natna pakhat, hmui leh mittui tlakna glands a vawt) .

He natna hian eng harsatna nge a thlen theih?

Hun rei tak chhung inflammation hian kan taksa peng hrang hrang a tichhe thei a ni. Hei hian scar tissue a siam chhuak thin. He scarring hian pancreas hnathawh a tichhe thei a ni. Tichuan, kan taksain a mamawh hormone leh enzyme a siam chhuak tawh lo va, chu chuan chaw ei lama harsatna leh zunthlum a thlen thei a ni.

Harsatna lian ber pahnih hmuh theih a awm a, chungte chu:

1. Biliary stricture: Kan thin (liver) atanga tui lo piang chhuak bile duct te chu pancreas kaltlangin an kal a. Pancreas a inflamed emaw scarred emaw a nih chuan heng duct te hi a block thei a ni. Tichuan, taksa chhungah bile a pung khawm a, chu chuan jaundice a thlen thin.

2. Pancreatic cancer hlauhawmna: Hei hi mi tam takin an hlauh ber a ni. Autoimmune pancreatitis hi cancer a ni lo. Mahse, chronic pancreatitis vei chuan, eng chhan pawh ni se, pancreatic cancer vei theihna chance a nei tlem hle (1% - 2%) vel a ni. Natna pahnih chhinchhiahna hi a inang vek avangin, an pahnih hi thliar hran a pawimawh hle. Chuvang chuan i doctor chuan he thil hi uluk takin a enfiah ang.

Engtin nge doctor-te hian he natna hi dik taka an hriat theih?

Hei hi detective thawnthu ang mai a ni. Test vawi khat lek pawhin natna hi a finfiah thei lo. Natna dang, a bik takin cancer hi paih chhuah a ngai bawk. Chuvang chuan doctor chuan test eng emaw zat a ti dawn a ni.

Enkawlnate chu engte nge ni?

Autoimmune pancreatitis enkawlna ber leh tangkai ber chu damdawi chi khat corticosteroids an tih hi a ni . Prednisone hi damdawi hman tam ber a ni. Heng damdawi te hian kan overactive immune system a ti reh a, inflammation a tihziaawm bawk.

Enkawlna hi damdawi dose sang tak atanga tan thin a ni . I symptoms leh test result a that chhoh zel chuan i doctor chuan a dose chu a tihhniam zauh zauh ang. A châng chuan, steroid i ei tawh loh hnuah, natna thunun tûra ṭanpui tûrin immunosuppressant damdawi dang pek i ni thei bawk.

Complication a awm chuan, bile duct obstruction ang chi hi chu a hranpaa enkawl a ngai dawn a ni. Entirnan, duct blocked hawn nan stent dah theih a ni. A tlem hle a, operation a ngai mai thei.

He natna nen hian nun hi eng ang nge ni ang?

Thu lawmawm tak chu autoimmune pancreatitis hi enkawl theih tak a ni . Steroid enkawlna i tan atanga kar tlemte chhungin i natna lan chhuahnaah hmasawnna nasa tak i hmu thei a ni. Mi tam tak chuan hun kal zelah damdawi ei hi an chawlhsan vek thei a ni.

Mahse, a chang chuan (a bik takin Type 1 AIP-ah chuan) enkawlna chawlhsan hnuah symptoms a lo lang leh thei (relapse) thei bawk. Chutiang hunah chuan damdawi chu a tlem zawka ei chhunzawm a ngai mai thei. I doctor chuan i dinhmun chu a enfiah chhunzawm zel ang a, i tana tha ber tur enkawlna ruahmanna a siam ang.

Hei hi natna râpthlâk tak a ni thei. Kum tam tak chhung chu symptoms chu hriat lohvin a awm thei a, symptoms a lan tak tak chuan a buaithlak thei bawk. Chuvangin diagnosis dik tak hmuh theih nan hun rei tak a ngai thei. Amaherawhchu, he natna hi enkawlna tha tak tak a awm tih hre reng ang che, enkawl a nih chuan i dam thuai thei a ni. Chu chuan chakna nasa tak a pe ang che.