Tunlai hian he ‘clear cell’ chi cancer, kal (Clear Cell Renal Cell Carcinoma - ccRCC) lo awm hi kan sawi dawn em ni?

Kan taksa peng pawimawh ber pakhat chu kal (kidney) hi a ni. Heng taksa peng te tak te pahnih, nitin kan thisen filter a, thil tul lo tak tak zun anga paih chhuaktu te hi kan taksaah filter pahnih ang mai an ni. Mahse, heng kal (kidney) te hian natna chi hrang hrang an nei thei bawk. Vawiin hian kal cancer chi khat, a nasat em em, mahse fimkhur a pawimawh hle. Hei hi `(Clear Cell Renal Cell Carcinoma)` a ni a, a tawi zawngin `(ccRCC)` a ni.

‘Clear cell renal cell carcinoma’ (ccRCC) tih hi eng nge ni?

A awlsam zawngin sawi ila, he `(Clear Cell Renal Cell Carcinoma - ccRCC)` hi kal cancer chi khat a ni. Kidney cancer chungchang kan sawi hian a tlangpuiin `(Renal Cell Carcinoma - RCC)` kan ti thin. He `(ccRCC)` hi a chi khat a ni.

Kan kal (kidney) hian a chhungah hian channel te tak te, filter ang chi a nei tih i hria em? Hengte hian thisen chhunga bawlhhlawh awmte chu filter-in zun angin an pass chhuak thin. He cancer hi chutiang channel line tu cell atang chuan a intan thin. Heng `(ccRCC)` cell te hi an inthen darh a, an pung chak hle a, tumor pakhat emaw a aia tam emaw an siam thin. A tlangpuiin kal pakhat a nghawng a, a chang chuan kal pahnih a nghawng thei bawk.

He natna lan chhuah dan engte nge ni?

A tam zawkah chuan he `(ccRCC)` hi a tir lamah chuan natna lan chhuahna lian tham a awm lo. Chu chu a hlauhawm deuh chu a ni. A chhan chu natna i vei tih pawh i hre lo mai thei. Mahse natna a zual zel chuan hetiang hi i tawng mai thei:

• Zun chhungah thisen a awm. A châng chuan zun chu a sen emaw, a sen emaw, a sen emaw pawh a ni thei. Doctor-te chuan hei hi ``hematuria'' an ti.
• Chauhna chu eng ang pawhin mut pawh ni ila, hah lutuk tihna a ni. Nilengin i chau hle mai thei.
• Chhan awm lova khawsik lo thleng. Natna dang nei lova khawsik chauh i neih chuan chu pawh chu ngaihven tur a ni.
• Kidney natna neiah chuan lump ang maiin a lang .
• Flank pain chu kal sir lama natna a ni . He natna hi a awm reng thei a, a lo thleng thei bawk.
• Sawifiah loha taksa rihna tlahniam. Diet leh exercise la lovin i taksa rihna i tihtlem mai mai a nih chuan chu chu ngaihtuah tur a ni.

Engvangin nge hetiang `(ccRCC)` hi a lo awm? A chhante chu engte nge ni?

Dik tak chuan, he `(ccRCC)` pawh tiamin, kal cancer tam zawk awm chhan dik tak hi hriat a la ni lo . Mahse, thil ṭhenkhat chuan a vei theihna a tipung tih hmuhchhuah a ni. Eng nge an nih i en ang u?

• Zuk leh hmuam hman : Hei hian zuk leh hmuam chauh ni lovin vaping pawh a huam tel bawk. Zuk leh hmuam a chemical tha lo tak takte hian kal (kidney) a tichhe thei a ni.
• Body Mass Index (BMI) kum 25 chunglam : A awlsam zawngin, thau lutuk/thau lutuk nih. Thau lutuk hian hormone a tidanglam thei a, harsatna dang a thlen thei a, chu chuan cancer vei theihna a tipung thei a ni.
• Thisen sang (hypertension): Hei hi i thisen sang a san lai a ni. Hetiang hlauhawmna hi thisen sang hian kal (kidney) a tihchhiat vang a ni thei.
• Hun rei tak chhunga kal natna avanga dialysis tih ngai : Dialysis nei te pawh hi kal cancer vei an hlauhawm hle.
• Hnathawhna hmuna chemical tha lo thenkhat nena inzawmna : Entirnan, solvent trichloroethylene, asbestos, leh cadmium te nena inzawmna nei te pawh hi an hlauhawm hle.
• Hun rei tak chhunga analgesics hman : Painkiller thenkhat, acetaminophen (Tylenol®) te hi i ei chhunzawm zel emaw, a tam lutuk emaw chuan i tan a tha lo.

He `(ccRCC)` hi tuin nge hmasawn ber thei ang?

Dik tak chuan tu pawhin he natna hi an nei thei a, chu chu ``(ccRCC)`` an ti a ni. Mahse, hmeichhia aiin mipain he natna hi an vei tam zawk tih hmuhchhuah a ni . Tin, kum 50 leh 70 inkar zingah a tam ber bawk.

American Cancer Society chhinchhiah danin kum tin United States-ah hian mi 81,000 chuang zetin kal cancer an vei tih hmuhchhuah a ni. Chung zingah chuan kal cancer chi khat chu ccRCC tih a ni .

He natna hi `(ccRCC)` an tih hi thlahtute atanga lo chhuak a ni em?

Thisen chhunga i chhungte, renal cell carcinoma vei i neih chuan, i kal cancer vei theihna chance a sang deuh mai thei. Amaherawhchu, Doctor-te chuan a chhan an la hre chiang lo.

Mi thenkhat chuan genetic condition an nei a, chu chuan ccRCC an vei theihna a tipung zawk a ni. Entirna pakhat chu Von Hippel-Landau (VHL) natna hi a ni.

Heng hunah hian thlah kal zelah genetic mutation a awm a, chu chuan taksa hmun hrang hrangah cyst leh tumor a siam thin. Heng tumor te hi a tlangpuiin cancer a ni lo. Mahse, heng chhungkaw zinga mite hian ccRCC hi an nei tam zawk thei a, kum pangngai aia kum naupang zawkah pawh a vei thei bawk.

Kum naupan lai atanga ccRCC i vei tih hmuhchhuah i nih chuan, emaw, tumor tam tak i neih chuan, i doctor chuan genetic testing neih a rawt thei ang .

He `(ccRCC)` natna hi engtin nge an hriat chhuah?

Kan sawi tawh ang khan kidney cancer hian a tir lamah hian symptoms a nei tlem hle fo thin. Chuvangin doctor-te chuan natna dang an zawn hian kidney tumor an hmu fo thin. Entirnan, kal lung (kidney stone) zawn nan MRI emaw CT scan emaw hmangin kal (kidney tumor) chu accident-in hmuhchhuah a ni thei.

Hetiang imaging test hmang hian tumor a awm leh awm loh a hriat theih. Mahse, scan atang chauh pawhin tumor hi benign nge malignant tih chiang taka hriat a harsa hle.

Diagnosis dik tak siam turin , doctorKidney biopsy tih theih a ni a, a nih loh leh operation tihchhuah a ngai bawk.

Surgery hmanga tumor hi lakchhuah a nih chuan tumor atanga tissue lakchhuah a ni a, cancer a awm leh awm loh test a ni. Chu result chu cancer a nih leh nih loh leh ``ccRCC'' tih chi khat a nih leh nih loh hriat nan hman a ni.

Mak tak maiin, kidney tumor te tak te, centimetre 4 aia lian lo 10 zinga 4 chauh hi benign tumor, renal oncocytomas ang chi an nih a rinawm.

(ccRCC) cancer hi eng stage nge ni?

`(ccRCC)` a vei tih hmuhchhuah a nih hnuah doctor chuan ``cancer staging`` a tifel thin. Chu chu tumor lian leh te, taksa peng dangah a darh tawh em tih te an en thin tihna a ni.

Clear Cell Renal Cell Carcinoma hi chi li a awm a.

• Chance a tlem poh leh cancer a na lo zawk.

Doctor chuan hengte hi a sawipui ang che:

• I cancer hi eng stage ah nge a awm.
• Taksa hmun danga a darh theihna tur chu eng nge ni?
• I tih leh tur chu engte nge ni ?

`(ccRCC)` enkawlna tur engte nge ni?

A tam zawkah chuan enkawl dan tur chu cancer hi kal pawn lama a darh leh darh lohah a innghat a ni. Awle, han en teh ang.

Cancer hi kal pawn lama a darh loh chuan:

Chutiang a nih chuan hetiang hian enkawl theih a ni:

• Surgery - Nephrectomy : Surgeon chuan kal cancer awmna hmun chauh a la chhuak thin. Hei hi partial nephrectomy an ti a. A dang pawhin kidney pumpui chu lakchhuah theih a ni bawk. Hei hi radical nephrectomy an ti a.
• Ablative therapies : Heng enkawlnaah hian percutaneous approach hmangin cancer cells te chu vun kaltlangin needle dahin an tichhia a ni. Chumi atan chuan hmanraw hrang hrang a awm. Entirnan, cancer cells te hi khaw lum lutuk (cryoablation) emaw, lum lutuk (thermal ablation) emaw hmanga tihchhiat theih a ni.

Cancer hi a darh tawh a nih chuan, a nih loh leh a darh theihna a sang hle a nih chuan:

Chutiang hunah chuan enkawlna kawng hrang hrang chu:

• Immunotherapy : Hei hian i taksa ngeia immune system tichakin cancer cells te tihchhiat a huam a ni. Chumi atana hman tur damdawi chu pembrolizumab (Keytruda®) emaw nivolumab (Opdivo®) emaw a ni.
• Targeted therapy : He enkawlna hian cancer cells te lo thang lian leh pung zel chu a titawp a ni. Chumi atana hman tur damdawi chu axitinib (Inlyta®) leh cabozantinib (Cabometyx®) te an ni.

`(ccRCC)` hi cancer na tak, darh chak tak a ni em?

`(carcinoma) chi dang zawng zawng ang bawkin he `(Clear Cell Renal Cell Carcinoma)` hi taksa peng dangah a darh (metastasize) thei a ni. Hetianga cancer darh tawh (metastatic cancer) enkawl hi a harsa deuh.

Kidney cancer chi dang nena khaikhin chuan ``(ccRCC)`` hi a na zawk tlangpui a, a darh chak zawk bawk .

Renal Cell Carcinoma hi a hnuaia hmun hrang hrangah hian a darh tam ber a ni:

• Lymph nodes a awm thin
• Chuap
• Adrenal glands (kidney chunglama awm) .
• Thin
• Thluak
• Ruh te

Engtiang chiahin nge (ccRCC) cancer hi a lo thang chak?

Clear Cell Renal Cell Carcinoma hi a lo thang chak dan hi a inang lo thei hle. Zirchianna pakhatah chuan kum khatah khawi hmunah pawh centimetre 0.2 atanga 6.5 (inches 0.07 atanga 2.5) vel an thang thei a ni. Kum khatah a pung zat chu centimetre 2.13 (inches 0.83) vel a ni.

`(ccRCC)` tan hian damchhuah zat chu engzat nge ni?

A tlangpuiin (ccRCC) kum nga chhunga dam rei zawng chu 50% leh 69% inkar a ni .

Mahse, hetianga dam leh theihna chance hi i tumor lian leh teah a innghat a ni. A tlangpuiin, tumor lian zawk emaw, taksa peng dangah `(ccRCC)` a darh tawh chuan enkawlna a hlawhtling lo zawk. Chutiang hunah chuan tumor lian tak a awm emaw, cancer a darh tawh emaw chuan kum nga chhunga dam rei zawng chu 10% vel a ni thei. Chuvang chuan a hmaa hriatchhuah a pawimawh a, a hmaa enkawl tan a pawimawh.

Engtin nge ka in enkawl ang?

Clear Cell Renal Cell Carcinoma i vei tih i hriat chuan rilru natna hrang hrang i neih hi thil pangngai a ni. Thil chi hrang hrang i nei thei a, chung zingah chuan hlauhna te, thinrimna te, lungngaihna te, lungkhamna te, leh lungngaihna te pawh a tel.

Mi tam tak chuan (ccRCC) chungchang a theih ang anga zir a, an hmangaih tak takte hnen atanga tanpuina dil hian thlamuanna an hmu thin. I thil tawn dik tak hrethiam thei (ccRCC) support group-a tel ve pawh a tha hle.

I medical team pawh rin a pawimawh hle bawk. Enkawl dan tur leh dam dan tur chungchanga zawhna i neih apiang zawt rawh.

I in enkawl dan dang thenkhat chu hetiang hi a ni:

• Doctor ten damdawi an pek zawng zawng chu an tih angin ei vek tur a ni .
• Protein leh calorie tamna ei tur ei a, thinrim loh tur .
• A tha thei ang berin mu rawh .
• Thâwk thûk tak, ngaihtuahna, yoga, art therapy, emaw puzzle ang chi thil tihlum thei thil hmanga stress enkawl tum.
• I taksain chakna a neih ang zat zat.Taksa tihchaknaah inhmang.

Engtikah nge Doctor ka hmuh ang?

Heng symptoms te hi i neih chuan doctor pan nghal rawh:

• Zun ah thisen a awm chuan.
• I kut ah lump emaw na emaw i neih chuan a bo lo .
• Sawifiah loh taka khawsik emaw i taksa rihna tlahniam emaw i neih chuan .

(ccRCC) enkawl i nih tawh chuan, natna lan chhuah thar i neih emaw, i natna a zual emaw chuan i doctor nen inbia nghal rawh . I natna lan chhuah dan tur an hrilh thei che a, i damdawi ei tur thlak dan tur an hrilh thei che a, enkawlna thar an rawt thei bawk. I enkawlna atana thil pawimawh tak chu a theih ang anga hrisel taka awm hi a ni.

Doctor hnenah eng zawhna nge ka zawh ang?

I doctor hnenah hetiang zawhna hi zawh a tha ang:

• "Ka tan enge inenkawlna tha ber?"
• "I recommend treatment hian eng side effect nge a neih?"
• "Metastatic cancer vei hlauhawmna ka nei em?"
• "Engtin nge he `(ccRCC)` hi a darh theihna tur hi ka tihtlem theih ang?"
• "Ka thisen chhungkuaah hian `(ccRCC)` vei theihna hlauhawm an awm em?"
• "Complication symptoms ka hriat bik tur a awm em?"

Heng zawhnate hi i tanpui nan chauh a ni. Doctor hnenah i rilrua i neih apiang zawt hreh suh, eng ang pawhin tenau pawh nise. Engkim chiang taka i hriatthiam a pawimawh hle.

‘Clear cell’ leh ‘papillary’ kidney cancer hi eng nge an danglamna?

Chungte chu ``Clear Cell Renal Carcinoma'' leh ``Papillary Renal Cell Carcinoma'' te an ni. An pahnih symptoms hi a inang hle. Enkawl dan pawh a inang hle.

A danglamna ber chu heng cancer cell te hi microscope hmanga en chuan engtin nge an awm tih hi a ni.

• Papillary cancer cells te hi sei tak, te tak te, kut zungtang ang maia lian angin an lang thin.
• `(ccRCC)` Cancer cell te hi bubble chiang tak ang maiin an lang.

Renal cell carcinoma vei mi 10 zinga pakhat vel chuan papillary type an nei a ni.

A tawp berah chuan hriat reng tur tlemte (Take-Home Message) .

Cancer i vei tih hriat a harsat theih zia ka hrethiam. Hlauhna, lungngaihna, thinrimna, buaina leh mahni chauha awm ang chi hriatnate chu vawi khatah a lo thleng thei che a ni. Heng zawng zawng hi vawi khatah i hre vek mai thei. A nih loh leh, he diagnosis hi i hmachhawn tum hian i rilru put hmang nen inzawmna i nei lo niin i inhria thei bawk. Eng thil pawh i hriat chu thil pangngai a ni tih hrethiam rawh.

Clear Cell Renal Cell Carcinoma (ccRCC) hi kal cancer chi hrang hrang zingah chuan a tam ber a ni. Kidney cancer dang aiin a thang chak zawk a, a na zawk thei bawk.

Harsatna tam tak i nei a, i ngaihtuahna leh i rilru put hmangte chu tu emaw hnenah i sawipui a ngai a ni.I doctor-te hnen atanga tanpuina dil hreh ngai suh la, i support system (chhungte, ṭhiante)-ah innghat rawh.

Hei hi zinkawng harsa tak a ni thei a, mahse step khat khatin la la, i chungah ngilnei takin awm rawh. Hriat hmasak leh enkawl hmasak hian danglamna nasa tak a thlen thei tih hre reng ang che. Nangmah chauh i ni lo.

` Kal cancer, ccRCC, Clear Cell Renal Cell Carcinoma, kal natna, cancer symptoms, cancer enkawlna, kal hriselna