He bacteria rapthlak tak hi i hre chiang em? (Carbapenem-Resistant Enterobacterales - CREs) Kan sawi dawn nia!

Natna thenkhat damdawi, chu chu (antibiotics), tih hi a chang chuan a thawk lo tih i hre tawh ngei ang. Chu chu tunlaia kan sawi tur dinhmun hlauhawm leh ngaihtuahawm tak zinga mi a ni a, chu chu (Carbapenem-Resistant Enterobacterales) emaw (CREs) bacteria infection te hi a ni. Hengte hian (antibiotics) chak tak tak, a tlangpuiin an pek thin thenkhat chu an chhang lo mai thei. Chuvangin, hei hi thawnthu serious deuh ni mahse, kan zavaia tan hian he thil hi kan hriat chian a pawimawh hle. Eng thil nge thleng tih hi i hrethiam mai ang u.

(Carbapenem-Resistant Enterobacterales) emaw (CREs) emaw chu eng nge ni?

A awlsam zawngin (Enterobacterales) hi bacteria pawl, inzawmkhawm, chhungkaw khat ang maia inzawmkhawm a ni. Heng bacteria te hian kan taksaah natna chi hrang hrang a thlen thei a ni. Tunah chuan heng (Enterobacterales) bacteria te hian a chang chuan (Carbapenems) an tih, (antibiotic) bik, chak tak, dodalna an lantir fo thin. (Carbapenems) laka invenna (Enterobacterales) bacteria te chu (Carbapenem-Resistant Enterobacterales) emaw (CREs) emaw kan tih te hi an ni.

Ngaihtuah teh, Doctor-te hian bacteria infection enkawl nan (antibiotics) an hmang thin. Mahse, heng bacteria te hi an fing hle. (antibiotics) (a bik takin damdawi in emaw, nursing home emaw-ah) an tawrh reng hian, chu (antibiotics) lakah chuan dam khawchhuah dan tur leh dam khawchhuah dan tur an zawng chhuak thin. Hei hi (resistance) kan tih chu a ni. Chuvangin (CREs) chu (Carbapenem) class (antibiotics) laka invenna nei tawh bacteria an ni.

He antibiotics class-a tel damdawi chi dang engemaw zat Carbapenems'' an tih hi a awm bawk:

• Ertapenem tih a ni
• Imipenem tih a ni
• Meropenem tih a ni

Hengte hi antibiotics chak tak tak an ni a, natna khirh tak tak tan pawh pek thin an ni. Chuvangin bacteria pakhatin hengte hi a do thei ta a nih chuan a natna chu tihdam a harsa deuh tihna a ni.

Bacteria (Enterobacterales) chi hrang hrangte chu engte nge ni?

Mi thenkhat chuan (CRE) tih tawi te hi (Carbapenem-resistant Enterobacterales) tihna atan an hmang a, thenkhat erawh chuan (Carbapenem-resistant Enterobacteriaceae) an hmang thung. (Enterobacterales) hi order lian tak, bacteria chi hrang hrang tam tak awmna a ni. Chhungkaw pathum, a nih loh leh suborder a nei a. Heng suborder pakhat chu (Enterobacteriaceae) a ni. He (Enterobacteriaceae) group hi kan hriat fo thin bacteria te awmna hmun a ni:

• Escherichia (kan hriat tam ber chu E. coli) .
• Klebsiella tih a ni
• Salmonella tih a ni
• Shigella tih a ni

CRE awm tam ber chu antibiotic-resistant strain Klebsiella pneumoniae leh E. coli te an ni. Klebsiella emaw E. coli emaw natna i neih vang mai mai chuan antibiotic-resistant a ni tihna a ni lo tih hriat reng a pawimawh.

(CREs) avanga hri kai awmte chu engte nge ni?

Heng (CREs) bacteria te hian i taksa hmun hrang hrangah natna a thlen thei a ni. Heng hri kai te hi a tam ber chu:

• Thisenah chuan(Thisen atanga hri kai) .
• Zun kawng natna (UTI) .
• Lung chhungah (pneumonia) .
• Pum chhunga (intra-abdominal abscess) 1.1.

Hetiang hmunah hian heng bacteria rukbo te hian awlsam takin natna an thlen thei a ni.

(CRE) hri kai hi engtiang chiahin nge a awm?

United States ang ram statistics i en chuan kum tin (CREs) vangin hri kai 13,000 vel an awm thin. Chung zinga 1,100 vel chu an thi thin. Sri Lanka-a Doctor-te pawhin he dinhmun hi an ngaihven hle a ni. A chhan chu chutiang resistant bacteria chu khawvel hmun hrang hrangah harsatna a lo ni chho zel a ni.

(CRE) hri kai chhinchhiahnate chu engte nge ni?

(Carbapenem-resistant Enterobacterales) natna lan chhuah dan hi i natna hmun azirin a inang lo. A lan chhuah dan tlangpui thenkhat chu:

• Khawsik
• Chills a awm
• Thâwk harsa
• Khuh
• Pum natna
• Zun laiin natna
• Surgery emaw hliam emaw hmuna sen, hring, leh hnim hring

Pawimawh: Heng symptoms te hi (CRE) infection chauh a ni lo. Bacteria infection dang pawhin heng symptoms te hi a thlen thei bawk. Chuvangin heng symptoms te hi eng emaw tal i neih chuan Doctor pan a tha ber.

(CRE) hri kai chhante chu engte nge ni?

A awlsam zawngin (CRE) infection hi (Carbapenem) an tih (antibiotics) laka inven thei bacteria atanga lo chhuak a ni. Hetiang (antibiotic) resistance hi bacteria te hian an neih chhan hrang hrang a awm a. Pakhat chu thilsiam chhunga thil nung dangte nena awm dun tura an lo thanglian dan hi a ni.

Damdawi in leh healthcare setting dang dangah chuan bacteria te hi antibiotics an dawng fo thin. A bik takin carbapenems ang chi antibiotics chak tak takte hi natna khirh tak enkawlna atana hman a nih avangin bacteria te hian an do theih dan tur an siam chhuak thei a ni. Heng bacteria te hian an resistance genes te chu bacteria dangte hnenah an hlan chhawn theihna mak tak an nei a . Hei hi horizontal gene transfer an ti a. Thian hnena thuruk hrilh ang bawkin heng bacteria te hian an do theihna chu midangte hnenah an sawi chhuak thin. Chutiang a nih loh chuan antibiotics atanga dam khawchhuak bacteria te hian an resistance genes te chu an pass thei a, resistant bacteria tam zawk an siam thei a ni.

Bacteria te (CRE) laka an do theih dan ber pakhat chu enzyme pakhat (Carbapenemase) siam chhuah hi a ni. He enzyme hian a tichhia a, (Carbapenem antibiotics) a tichhia a ni. He enzyme hian scissors te tak te hmanga damdawi a tan ang chiah hian hna a thawk a ni. Tichuan damdawi chu a thawk thei lo.

Engtin nge CRE te hi an inthlunzawm?

Carbapenem-resistant Enterobacterales bacteria hi i vunah emaw, i gastrointestinal tract (guts)-ah emaw natna siam lovin i awm thei a ni. Hei hi colonization an ti a.CREs hi CRE natna vei damlo atanga kai theih a ni a, a nih loh leh bacteria nena inzawm lo, symptomatically colonized atanga kai theih a ni bawk.

Damdawi in emaw, healthcare setting dang emaw-ah (CRE) infection i vei theihna hlauhawm ber i ni. Hei hi a chhan chu kan vunah leh kan taksaa awm bacteria te hian antibiotics an tawrh hian an do thei lo thei a ni. (CRE) infection hi a hnuaia mi ang hian i hmu thei ang:

• An vunah bacteria nei mi pakhat khawih hmangin (entir nan, chu mi chuan a kut a silfai tha lo a nih chuan).
• From dirty surfaces , a bik takin sink leh toilet te.
• Damdawi hmanraw bawlhhlawh leh damdawi hmanrua i taksaa dah (e.g., central venous line, thawkna tube) atang hian.

(CRE) hri kai vei zingah tute nge hlauhawm ber?

(CRE) infection i vei theihna chance sang zawk i nei thei a, chu chu:

• Central venous line (main vein-a dah tube), thawkna tube, feeding tube emaw, tube emaw device dang emaw i taksaa dah i neih chuan heng hmang hian pawn lam atangin CRE te hi i taksaah a lut thei a ni.
• Antibiotics i ei rei tawh emaw, i ei fo chuan hun kal zelah bacteria te hian an do theihna an nei thei a ni. Hei hian kan gut chhunga bacteria "tha" (tha lo) te chu a that thei a, bacteria dangte chu control theih lohvin an lo thang lian thei a, natna hrik a thlen thei bawk.
• I immune system tichak lo thei hriselna dinhmun hnuaia awm i neih chuan . Entirnan, HIV, thisen cancer, zunthlum, emaw, taksa peng dang emaw, stem cell thlak emaw i neih chuan i hlauhawm zawk a ni. Hei hi a chhan chu heng dinhmun hnuaiah hian taksa tan natna hrik dona a harsat zawk vang a ni.
• Nitin hnathawhnaah tanpuina i mamawh a nih chuan, inbual leh toilet hman ang chi , bawlhhlawh (leh gastrointestinal tract atanga bacteria) nena inzawmna i neih theihna a sang zawk thei a, chu chuan CREs a tidanglam thei a ni.
• If you have been hospitalized for a long time , a bik takin thla ruk kalta chhunga United States pawna damdawi inah i awm tawh a nih chuan. United States-ah hian CRE hi a pung chho zel a, mahse ram pawnah chuan a tam zawk hle.

(CREs) avanga harsatna awm thei te chu engte nge ni?

Doctor ten antibiotics hmanga bacteria infection an control theih loh chuan taksa pum puiah a darh thei a, organ failure ang chi harsatna thihna thlen thei a ni. Hei hi CRE infection hlauhawmna lian ber a ni.

Engtin nge (CRE) infection hriat theih ang?

Bacteria infection symptoms i neih a, antibiotics hmanga a reh loh chuan i doctor chuan CRE infection i nei niin a ngai mai thei. Chumi hnuah chuan i taksa atangin sample an la ang a, bacteria awm leh awm loh an enfiah ang. Heng sample-te hi a hnuaia mi ang hian a ni thei:

• Thisen
• Zun chhuah
• Ek
• Hliam atanga tui emaw tissue emaw

Laboratory chuan heng sample-a bacteria awmte hi CRE'' an nih leh nih loh a hre thei a ni. I taksaa damdawi hmanrua i dah tawh emaw, tun hnaia damdawi ina i awm tawh emaw a nih chuan i doctor hnenah hrilh theihnghilh suh.

CRE te hi engtin nge enkawl an nih?

CRE enkawl hi a harsa thei hle a, a chhan chu i hman tlangpui antibiotics te hian hna an thawk lo. Chuvangin, i doctor chuan antibiotic danglam tak a pe mai thei che a ni. A nih loh leh, bacteria carbapenemase enzyme titawp thei damdawi dang nen carbapenem antibiotic an pe thei bawk. Laboratory-ah chuan damdawi chi hrang hrang test theih a ni a, engte nge CRE-a hnathawk tih hriat theih a ni.

(CREs) enkawlna atana hman (Antibiotics) chi hrang hrang

Doctor-te’n CRE enkawlna atana an hman antibiotics chi hrang hrang – anmahni chauh emaw, an hman dun emaw – chu hetiang hi a ni:

• Polymyxin/Colistin tih a ni
• Tigecycline tih a ni
• Fosfomycin tih a ni
• Aminoglycosides (e.g. gentamicin emaw tobramycin emaw) te hi a tha hle.
• Rifampin tih a ni
• Carbapenem (inhibitor nei) 1.1.

Heng damdawi te hi damlo dinhmun, a kai dan, leh bacteria invenna (resistance pattern) a zirin thlan a ni.

(CRE) infection hi engtiang chiahin nge a nasat?

CRE hian natna khirh tak, enkawl harsa tak tak a thlen thei a ni. Mi thenkhat chuan nunna atana hlauhawm infection an nei thin. CRE infection i neih chuan damdawi inah enkawl i ni ang a, chutah chuan medical staff te chuan uluk takin an enkawl thei ang che.

(CRE) atanga recovery rate chu engzat nge ni?

Zirna hrang hrangah CREs avanga thihna rate hi natna kai awmna hmun azirin a inang lo tih hmuhchhuah a ni. Entirnan, CRE vanga zun kawng (UTI) vanga thihna rate hi 13% vel a ni a, CREs avanga thisen kai vanga thihna rate hi 50% emaw a aia tam emaw a ni thei. Heng statistics te hi en hian hei hi eng ang taka pawi nge a nih theih tih i hmu thei ang, a dik em?

CRE te hi ven theih a ni em?

Healthcare provider, doctor leh nurse te chuan healthcare-acquired infections (CREs) ven nan himna leh sterilization dan bik an zawm a ni. Chung zingah chuan:

• Kut sil fo thin ang che.
• Disinfecting surface te pawh a awm bawk.
• Antibiotics hi bacteria infection nei tan chauh pek a nih theih nan hma la rawh. (Viral infection tan antibiotics hi a \angkai lo.)
• Damdawi hmanrua te sterilization.

CRE natna laka invenna kawngah pawh hetiang hian i pui thei bawk:

• Kut sil fo la, uluk takin silfai thin ang che. Hei hi a pawimawh hle a, taksa chak lohna nei emaw, inbual emaw, toilet hmang emaw tanpui ngai emaw i enkawl a nih chuan.
• I taksaa dah damdawi hmanrua, catheter ang chi i hman a ngai tawh a nih chuan , i doctor hnenah eng chen nge a hmunah dah tur tih leh hmanrua a awm laiin natna hrik laka invenna tur eng nge i tih tur tih zawt rawh.

Engtikah nge ka doctor ka hmuh ang?

Damdawi hmanrua dah i neih emaw, i taksa hriselna a chak lo emaw a nih chuan, i doctor hnenah eng natna chhinchhiahna nge i fimkhur tur tih zawt rawh. Symptom rinhlelh awm i neih chuan Doctor pan tur a ni.

Damdawi ina i awm lai pawhin i medical team nen inbiakpawhna tha tak neih a pawimawh. Infection chhinchhiahna eng emaw, natna, thinlung thawk chak, chak lohna emaw, khawsik emaw i neih chuan hrilh nghal rawh.

Engtikah nge emergency room (ER) ah ka kal ang?

Natna khirh tak chhinchhiahna i neih chuan emergency room-ah kal rawh. A lan chhuah dan chu:

• Khawsik chu degree Fahrenheit 103 (40 degree Celsius) aia sang a ni.
• Natna nasa tak a nei.
• Seizures a awm thin.
• Buaina emaw, ngaihtuahna buai emaw.
• Thisen sang tlahniam nghal (symptoms: chak lohna, luak chhuak, muhil).

Doctor hnenah eng zawhna nge ka zawh ang?

I doctor hnenah hetiang zawhna hi zawh hi a \angkai thei ang:

• Eng enkawlna kawng nge ka neih?
• Engtikah nge dam ka beisei theih ang?
• Engtin nge he natna hi ka neih?
• Nakin lawkah hetiang hri kai tur hi eng nge ka tih theih ang?

A tawp berah chuan thil hriat reng tur (Take-Home Message) .

Carbapenem-resistant Enterobacterales (CREs) hi bacteria chi khat a ni a, natna khirh tak tak a thlen thei a, enkawl harsa tak a ni. Chuvangin i healthcare provider-te chuan damdawi in leh hun rei tak enkawlna hmunte chu thianghlim leh him taka awmtir turin nasa takin hma an la a ni. Sri Lanka-a doctor leh health official-te pawh he dinhmun hi an fimkhur hle a ni.

Infection na tak symptoms i neih chuan, a bik takin i taksaah medical device dah i nih emaw, immunocompromised i nih chuan doctor pan nghal rawh.Healthcare facility-ah i awm tawh a nih pawhin i doctor-te hnenah hriattir nghal rawh. Damdawi lam harsatna i neih te, implanted device i neih te, tun hnaia damdawi ina hun tam tak i hman tawh emaw te chu i doctor te hnenah hrilh rawh. He information hian i symptoms awm chhan chu rang taka hriat theih nan a pui ang a, infection eng pawh a rang thei ang bera enkawl turin a pui bawk ang. Hrisel takin awm rawh!