Midang ek chu midang natna enkawlna atana hman a ni tih ngaihtuah chu thil mak deuhin a ri mai thei, a dik em? Mahse hei hi natna khirh tak tak thenkhat tan damdawi lama hmanraw tangkai tak a ni. Vawiin hian he enkawlna kawng mak tak, mahse pawimawh tak, fecal microbiota transplantation (FMT) an tih hi kan sawi dawn a ni.
Fecal transplant tih hi eng nge ni?
A awlsam zawngin, hei hian mi hrisel tak ek sample tlemte lak a, natna vei mi pakhat colon-a dah luh a huam a ni. Hei hi a nuam lo hlein a lang thei. Mahse stool sample hrisel takah chuan microorganism (microbiota) \angkai tak tak maktaduai tam tak a awm a. Heng microorganisms te hi colon natna takah an luh chuan a hriselna siam that leh turin thilmak an ti thei a ni.
Tunah hian doctor-te chuan he enkawlna hi intestine-a bacteria infection na tak takte enkawlna atan an rawt ber a ni. He transplant hian bacteria tha tak tak a tir nasa hle a, chu chuan natna hrik kai chhunga bacteria tha lo, natna thlentu te chu a do thin a ni. Heng bacteria tha tak takte hi a bo chuan kan intestine chhunga microbial system (gut microbiome) balance chu a lo awm leh ta a ni.
Engtin nge hei hian hna a thawh? Kan pum chhungah eng thil nge thleng?
I gut chu huan mawi tak angin ngaihtuah rawh. He huanah hian kan mamawh thlai tha (bacteria tha) te, thlai tha lo (bakteria tha lo) te pawh a awm ve ve bawk. Engkim a inthlau phawt chuan huan a mawi a, chu chu kan hrisel tihna a ni.
Mahse kan ei thin damdawi thenkhat, a bik takin antibiotics te, natna thenkhat te leh thil dang te hian he huana thing tha tak tak tam tak hi a that thei a ni. Chuti a nih chuan eng nge thleng? Thlai, a nih loh leh bacteria tha lo chuan huan pum pui chu a luah khat a, a darh chak hle. Chutah chuan kan gut chu a balance lo a, kan na ta a ni.
Fecal transplant chu huan, hnim hringin a chim tawh chu phun thar leh ang a ni a, chu chuan thlai hrisel (bacteria tha) sang tam tak a rawn keng tel a ni. Heng bacteria tha tharte hian bacteria tha lo te nen an inel a, an thunun a, gut chhunga balance hrisel tak an siam leh thin.
He damdawi hi eng ang natna atan nge hman a nih?
Tunah hian he enkawlna hmanraw hi a hlawhtling ber a, C. difficile infection (CDI) recurrent C. difficile infection (CDI) a enkawl tih finfiah a ni a, hei hi bacteria C. difficile avanga intestinal infection chi khat , antibiotics hmang pawha control harsa tak a ni.A châng chuan antibiotics-in he natna hi a thunun theih loh chuan fecal transplant hian mak tak maiin hlawhtlinna a nei ṭhin.
Amaherawhchu, doctor leh scientist-te chuan he inenkawl dan hi natna dang tam tak tan pawh a tangkai thei niin an ngai. A chhan chu kan intestine chhunga microorganisms te hian kan digestive system chauh ni lovin kan metabolism leh immune system ah pawh nghawng lian tak a nei a ni. Chuvangin natna dang tam tak a tihdam theih leh theih loh zirchian mek a ni.
| Fecal Transplant hmanga enkawlna tur condition dangte zirchian mek a ni | |
|---|---|
| Digestive system natna te | - Inflammatory Bowel Disease (IBD) a ni a, a rilru a hah lutuk a, a rilru a buai em em bawk a. - ``Irritable Bowel Syndrome (IBS) natna a ni tih hi a chiang hle. |
| Metabolic natna te | - Thau lutuk - Thin natna - Zunthlum |
| Thil awmdan dang | - Ei leh in allergy nei - ``Autism Spectrum Disorder (ASD) tih a ni a, a rilru a hah lutuk a, a rilru a buai em em bawk a. - Lungkhamna leh Depression - `Multiple Sclerosis (MS) natna vei te` |
Engtin nge fecal transplant hi tih a nih? Eng hmanrua nge ni?
He stool sample hrisel tak hi damlo colon-ah dah theih dan kawng hrang hrang a awm. I doctor chuan i dinhmun nena inmil ber tur a thlang ang.
| Enkawl dan tur | Hrilhfiahna awlsam tak |
|---|---|
| Colonoscopy hmanga enfiah a ni | Camera (colonoscope) nei tube te tak te chu anus kaltlangin dahin intestine lian takah an kal tlang a. He tube hmang hian stool fluid chu intestine-ah direct-in a inject theih a ni. Hei hi hmanraw hman tlanglawn ber leh hlawhtling ber a ni. |
| Upper Endoscopy hmanga enfiah a ni | Tube (endoscope) chu ka chhung emaw, hnar emaw hmangin pum emaw, small intestine emaw chhungah dah a ni. Mahse, he method hi a hlawhtling lo hle a, a chhan chu microorganisms te hian intestine lian an thlen hmain small intestine kaltlangin hla tak an kal a ngai a ni. |
| Enema a ni | Fecal fluid hi tube te tak te, rectum chhunga dah hmangin a lut thin. Hetiang method hi a hlawhtling zawk a, a chhan chu microorganisms te hi large intestine ah direct in an kal a ni. United States-a FDA-in a pawmpui hmasak ber, Fecal Transplant chu hetiang hian pek a ni. |
| Oral Capsule hmanga siam a ni | Hei hi hmanraw thar ber leh awlsam ber a ni. Pills, dried, frozen fecal microorganisms awmna pills chu tui nen i ei thin. Heng pill te hi intestine lian tak thlenga inthiar theih loh tura siam a ni. |
He enkawlna atana stool hi khawi atanga i hmuh nge?
Chumi atan chuan volunteer (donors) hrisel tak takte hnen atangin bawlhhlawh an la khawm thin . Donor atana mi an thlan hmain medical test khauh tak tak an nei thin. Chu mi ek chhungah chuan 100% infectious agents emaw disease germs emaw a awm loh nan an enkawl thin.
Stool sample an lak zawh hnuah lab-ah an thawn a, an tifai a, saline ang chi liquid nen an pawlh a, an filter a, liquid-ah an siam a ni. A châng chuan hei hi a hnua hman tûrin frozen-ah an dah a, a nih loh leh an vawt a, capsule-ah an siam bawk.
Tute nge stool donor ni thei lo?
Hei hian mi pakhat bawlhhlawh chu mi danga dah hmaa testing engzat nge tih thin tih hriatna a pe ang che. A hnuaia condition nei tumah hi donor atan thlan an ni lovang.
- Tun hnaia antibiotics i hman tawh chuan.
- Bacteria infection hlauhawm dang `E. coli` tih a ni.
- Hepatitis, HIV, COVID-19 ang chi virus infection i neih chuan.
- Intestine-ah parasite a awm chuan.
- Ruihhlo i hman chuan.
- Inflammatory bowel disease (IBD) emaw autoimmune natna emaw i neih chuan.
- Chhungkaw zingah cancer vei tawh an awm chuan.
He enkawlna hian eng hlawkna leh hlauhawmna nge a neih?
A thatna ber chu
He enkawlna hian C. diff infection lo awm leh tur venna atan 80% atanga 95% velin a thawk tha hle . Hei hi he natna tan hian beiseina lian tak a ni a, a tichak lo em em a, antibiotics pawhin a thunun thei lo.
Side effects leh risk te pawh a awm thei
Enkawl hnuah ni khat emaw ni hnih emaw chhung chu harsatna tenau te a awm thei.
- Pum natna, pum nasat
- Nausea emaw, luak chhuak emaw
- Pum natna
- Mi thenkhat tan chuan khawsik leh khawsik
Hengte hi a na lo tlangpui a, ni hnih vel chhungin a reh thin.
Risk lian ber chu, a tlem hle nachungin, a petu taksaa hrik hlauhawm tak control a nih chuan a dawngtu taksa chak lo takah a lut thei a, natna kai a thlen thei a ni. Mahse he hlauhawmna tihziaawm nan hian donors te chu uluk takin screening an nei a, stool sample te pawh uluk takin an tifai thin. Tunlai thil hman phalna nei tawhte nen hian he risk hi a hniam hle.
He enkawlna hi mak tak angin lang mahse, a hnuaiah hian science tam tak a awm a ni. Kan taksaa microbes te tak te te hian kan hriselna a nghawng theih dan entir nan a tha hle. C. diff vei damlo tan chuan hei hi nun tidanglam thei tak a ni.
Take-Home Thuchah a ni
- Fecal transplant hi thil mak tak angin a lang thei a, mahse natna khirh tak tak, recurrent C. diff ang chi tan chuan damdawi tha tak a ni.
- Hei hian mi hrisel ek atanga ‘bacteria tha’ chu damlo intestine-a luhtir a, chutah chuan microbial balance siam that leh a huam a ni.
- Enkawlna atana hman thin bawlhhlawh sample te hi natna engmah a awm loh nan uluk takin test an nei thin a, chuvangin himna chungchangah fimkhur hle a ni.
- Hei hi in lama tih theih a ni lo. Hei hi damdawi in emaw clinic emaw-a doctor thiam tak takte tih specialized medical procedure a ni.
- Nangmah emaw, i hriat mi emaw, antibiotics-in a thunun theih loh intestinal infection lo awm leh zel a nih chuan, he enkawlna kawng hi i doctor nen sawiho rawh .
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