Imatinib tablet chungchang hi i zir dawn em ni? Cancer dona kawngah tanpui rawh!

Nangmah emaw, i hriat mi emaw hian cancer hi i do a ngai tawh em? Chutiang hunah chuan Doctor ten damdawi chi hrang hrang min pe thin a ni lawm ni? Imatinib hi damdawi bik a ni a, chutiang cancer cells control nan a pui a ni. Vawiin hian he damdawi chungchang hi chipchiar zawkin sawi ila, kan sawi dawn em ni?

Imatinib hi eng damdawi nge ni?

A awlsam zawngin Imatinib hi damdawi hmasawn tak a ni a, cancer cell te chu a target a, an thanlenna a titawp thei a ni. Sniper ang bawkin cancer cell-a protein bikte chu a target a, chutih rualin cell hrisel tam thei ang ber a humhim bawk. Hei hian cancer cells te chu a inthen darh a, a darh zel loh nan a tikhawtlai a ni.

He damdawi hi market-a a hming dang chu Gleevec tih a ni. I doctor pawhin he damdawi hi he hming hian a sawi thei bawk.

He damdawi hi eng ang natna atan nge hman a nih?

He damdawi, Imatinib tia koh hi leukemia chi hrang hrang enkawlna atan hman a ni ber a, chungte chu thisena cancer lo awmte an ni. Chu bakah, a:

• Myelodysplastic Syndromes hi ruhro (bone marrow) nena inzawm natna a ni.
• Cancer chi dang thenkhat tan chuan.
• Kan chaw ei dan (i.e., intestines)-a lo awm tumor chi hrang hrang tan pawh hman a ni a, chu chu GISTs (Gastrointestinal Stromal Tumors) an ti a ni.

Mahse hre reng ang che, doctor-te chuan a chang chuan he damdawi hi natna dang atan an hmang thei a, chuvangin he damdawi hi engvangin nge i pek tih zawhna i neih chuan i doctor emaw pharmacist emaw zawh hi a tha ber fo ang.

Damdawi ei hmaa doctor hnena i hrilh tur te chu engte nge ni?

Imatinib i ei tan hmain doctor hnenah i hrilh ngei tur thil tlemte a awm. I hrilh loh chuan i tan an inhmeh lo mai thei a, harsatna dang an thlen thei bawk. Chuvangin hetiang hian hrilh ngei ang che:

• Thisen chhuah harsatna i neih chuan.
• Tunah hian infection i neih chuan - a bik takin viral infection chickenpox leh herpes ang chi te.
• Lung natna emaw, thinlung natna emaw i neih chuan.
• Kidney natna i neih chuan.
• Liver natna i neih chuan.
• Lung natna i neih chuan.
• Pum lama harsatna i neih chuan.
• Tun hmaa Imatinib allergy i neih tawh chuan, emaw, damdawi, ei tur, dye, emaw, preservative dang emaw allergy i neih tawh chuan.
• Naupai emaw, nau pai tum emaw i nih chuan.
• Nu hnute pe lai i nih chuan.

He thu hi doctor hnena pek hi i himna atan a pawimawh hle!

He damdawi hi engtin nge dik taka hman ang?

He damdawi ei dan dik tak hriat a pawimawh hle. Doctor sawi ang chiah kha i zawm tur a ni.

• He pill hi tui glass lian tak nen ei tur a ni . Pill hi tui tlemte nen ei loh tur.
• Chaw ei ruala lak a tha ber. Hei hian pum na leh rilru hahna a tiziaawm thei a ni.
• He damdawi hi grapefruit tui nen hian eng vang pawhin ei loh tur a ni. Grapefruit tui hian he damdawi hman tangkai dan hi a tibuai thei a ni.
• Damdawi chu i doctor-in a pek ang chiah chiah, a hun takah, a zat dik takah ei rawh. Doctor-in a tih aia tam ei ngai suh, a nih loh leh ei tam zawk ngai suh.
• He damdawi hi i doctor thurawn tel lo chuan ei nghal vat suh.

Mi thenkhat chuan pills ei harsa an ti thin a ni lawm ni? Chutiang harsatna i neih chuan i doctor, damdawi lam thiam, a nih loh leh healthcare professional nen inbia ang che. Chumi kawngah chuan an pui thei che a ni. Pill chu tuiah a hmin a, a in theih dan a awm thei a, mahse chu chu doctor thurawn hnuaiah chauh tih tur a ni.

He damdawi hi naupangte hnena pek ni ta se engtin nge ni ang...?

Ni e, thil bik thenkhatah chuan Imatinib hi naupang kum khat mi lek tan pawh pek theih a ni. Mahse chu chu naupang enkawltu doctor-in a rel a ni. Naupangte hnena pek dawnin a bik takin fimkhur tur tlemte a awm. Chuvang chuan he damdawi hi naupang hnenah i pe dawn a nih chuan Doctor nen sawiho a, engkim hrilhfiah a pawimawh hle.

Damdawi i ei sual palh chuan engtin nge i tih ang?

Chutiang a nih chuan, chu chu i ngaihtuah aia tam i ei tawh nia i hriat chuan poison control center emaw, i bula damdawi in emergency room emaw i call nghal tur a ni. Hun khawhral suh. Hei hi i tan damdawi a ni a, tumah share suh.

Damdawi ei tur appointment i neih loh chuan engtin nge i tih?

Dose i ei theihnghilh palh a nih chuan i hriatreng veleh ei nghal rawh. Mahse, i dose leh tur hun a lo thleng tawh a nih chuan missed dose kha skip la, i dose leh tur chu a hun ruatah ei rawh. Dose theihnghilh tawh chu siam that nan double dose ei ngai suh. Chutianga tih chuan damdawi i ei zat a tipung thei a ni.

Eng damdawi dang nge he damdawi nen hian inzawm thei?

Hei hi a pawimawh hle a ni . Imatinib hian damdawi dang i ei lai nen a inzawm thei a ni. Chumi awmzia chu chu damdawi nena ei dun chuan Imatinib nghawng chu a danglam thei a, a nih loh leh damdawi dang nghawng chu a danglam thei a, a side effect pawh a pung thei tihna a ni.

Chuvangin Imatinib i ei dawnin i damdawi ei zawng zawng (i doctor-in a pek, damdawi dawr atanga i lei te, hnam damdawi, herbal products, vitamins) te chu i doctor hnenah i hrilh vek tur a ni. Tin, zu i in emaw, zu i in emaw, ruihhlo dang i hman emaw chuan doctor i hrilh tur a ni.

Imatinib hian a hnuaia damdawi te hi a inzawm thei a ni:

• HIV emaw AIDS emaw tan antiviral damdawi thenkhat
• Bosentan a ni
• Cisapride chuan a rawn ti a
• Clarithromycin hmanga siam a ni
• Cyclosporine a ni
• Dexamethasone a ni
• Diltiazem a ni
• Ergot alkaloids (e.g., dihydroergotamine, ergonovine, ergotamine, methylergonovine) te hi a awm a, a chhuahna tur hmun leh a hmanna tur hmun hi a inang lo hle.
• Erythromycin hmanga siam a ni
• Grapefruit emaw grapefruit tui emaw - Sawi tawh ang khan hei hi pumpelh ngei ngei tur a ni.
• Cholesterol tihhniamna damdawi (e.g. atorvastatin, lovastatin, simvastatin) .
• Depression, lungkhamna emaw, rilru lam natna emaw damdawi
• Antifungal damdawi (e.g. ketoconazole, itraconazole) te hi a tha hle.
• Lung natna mumal lo damdawi (e.g. amiodarone, bepridil, dofetilide, encainide, flecainide, propafenone, quinidine) .
• Seizure damdawi (e.g. carbamazepine, phenobarbital, phenytoin) te hi a tha hle.
• Mut theihna damdawi
• NSAID (e.g. ibuprofen, naproxen) te hi a tha hle.
• Pimozide a ni
• Rifabutin a ni
• Rifampin a ni
• Sildenafil a ni
• Sirolimus a ni
• A thinghnah chu St. John’s wort a ni
• Tacrolimus tih hi a ni
• Vaccine pek dan tur
• Verapamil a ni
• Warfarin - thisen zam tur venna damdawi a ni

He list hi a kimchang lo hle. Chuvangin , i damdawi ei zawng zawng hi i doctor hnenah hrilh vek a tha ber. A bik takin damdawi paracetamol, aspirin, ibuprofen, ketoprofen, leh naproxen te i ei hmain i doctor nen inbia ang che.

Damdawi ei huna fimkhur tur thilte chu engte nge ni?

Imatinib i ei lai hian i doctor chuan i hriselna a enfiah reng ang. Hei hian damdawi hian i taksa a nghawng dan leh a side effect a awm leh awm loh hriat nan thisen test mumal tak neih a huam ang. Symptom thar i neih chuan doctor hnenah i hrilh nghal tur a ni.

Skin reaction na tak tak awm thei te chu hre reng ang che.

He damdawi hian mi thenkhatah vun natna nasa tak a thlen thei a ni. Hengte hi damdawi ei tan atanga kar emaw thla emaw hnuah a thleng thei a ni. Khawsik emaw, khawsik ang chi natna emaw i neih chuan doctor hnenah hrilh nghal rawh.Rash chu sen emaw purple emaw a ni thei a, chutah chuan blister leh peel a ni thei. A nih loh leh, vun sen (red rash) hian hmai, hmui, kawr, emaw, kawrfual (arpits)-a lymph node hring (swellen) a awm thei bawk.

Infection lakah inveng rawh

Khawsik, khawsik, ril na, khawsik ang chi symptom i neih chuan mahni invenna nei suh. Doctor hnenah thurawn dil nghal rawh. He damdawi hian i taksain natna hrik a do theihna a ti tlem thei a ni. Chuvangin damlote lakah a theih ang anga inthiarfihlim tum ang che.

Thisen chhuah theihna a awm

He damdawi hian thisen chhuah emaw, hliam emaw i neih theihna a tipung thei a ni. I ha i hliam fo, hnar thisen chhuak, ha i sil laiin i hmui thisen chhuak, emaw, thisen chhuak danglam tak i neih chuan doctor hnenah hrilh rawh.

Mutthilh leh luak chhuak

He damdawi hian muthilh emaw, luak emaw a siam thei che a ni. Chuvangin, he damdawi hian engtin nge a nghawng che tih chiang taka i hriat hma chuan lirthei khalh te, machinery hman te, leh ngaihtuahna seng ngai thil engmah tih loh tur a ni.

He damdawi hi nu naupai leh nau hnute pe lai tan engtin nge a nih?

Hei hi thil pawimawh tak a ni .

• He damdawi ei lai leh damdawi ei khap hnu ni 14 chhung chu naupai loh tur a ni.
• Hmeichhiain nau pai a tum a nih chuan, a nih loh leh naupai a nih a rin chuan a doctor hnenah a hrilh tur a ni. He damdawi hian nausen piang lo tan side effect na tak a thlen thei a ni. I doctor emaw pharmacist emaw hnenah thu belhchian dawl zawk zawt rawh.
• He damdawi i ei lai leh damdawi i ei zawh hnu thla khat chhung chu naute hnute pe suh.

He damdawi hian eng side effect nge a neih theih?

Damdawi dang ang bawkin Imatinib hian mi thenkhatah side effect a nei thei a ni. Mi zawng zawngin an hmu vek lo a, mi thenkhat erawh chuan an hmu ve tho. Chung zinga ṭhenkhat chu i doctor hnenah i hrilh nghal tur thil a ni , ṭhenkhat erawh chu a na lo zawk a, ni engemaw zat hnuah a bo vek ang. Mahse, an awm reng emaw, an tibuai emaw chuan i doctor hnênah i hrilh tûr a ni .

Side effects i doctor hnena i hrilh nghal tur:

• Allergy symptoms: vun rawng, vun hring emaw, hives emaw, hmai, hmui, lei hring.
• Thâwk lama harsatna a awm.
• Mit hmuhna lama inthlak danglamna.
• Zun dum.
• General ill feeling emaw flu ang chi natna emaw a awm thei.
• Stool rawng hring hring.
• Chaw ei chakna hloh.
• Thisen zat tlahniam: He damdawi hian thisen var, thisen sen, leh platelet te a ti tlem thei a ni. Hei hian natna hrik i vei theihna leh thisen chhuah theihna a tipung thei a ni.
• Kawngkhar natna.
• Rash, khawsik, leh lymph node hring.
• Vun a sen, a hring, a hring emaw a hring emaw a, hengte hi ka chhungah pawh a awm thei bawk.
• Right upper belly na a awm.
• Platelets hniam emaw thisen chhuak emaw chhinchhiahna: hliam, vunah pinpoint red spot, dum, tarry stool, zun chhunga thisen, hnar thisen.
• Thisen sen tlahniam chhinchhiahna: chak lohna danglam tak, hahna, rilru hahna, leh lu hah.
• Hri kai chhinchhiahna: khawsik emaw, khawsik emaw, khuh, ril na, na emaw zun harsa emaw.
• Ke emaw ke ruh emaw a hring chhuak.
• Zun chhuah harsatna emaw, zun tam dan inthlak danglam emaw.
• Luak chhuak.
• Mit emaw vun emaw a sen (yellowing) thin.

Side effects, a tlangpuiin damdawi lam enkawl ngai lo (mahse a awm reng emaw, a buaithlak emaw chuan doctor hnenah hriattir tur a ni):

• Ei duhna a tlahniam.
• Kawthalo.
• Insomnia (mut harsat).
• Lu na.
• Lungchhung natna.
• Joint natna.
• Muscle cramps emaw natna emaw.
• Luhai.
• Pum natna (upset stomach) a awm.

He list-ah hian side effect awm thei zawng zawng a tel lo mai thei. Thil danglam tak i hriat chuan doctor zawt la. Side effects te chu FDA (Food and Drug Administration) hnenah 1-800-FDA-1088 ah i report thei bawk (Sri Lanka ramah chuan i doctor kaltlangin drug regulatory authority kaihhnawih hnenah i report thei bawk).

He damdawi hi engtin nge ka dahkhawm ang?

He damdawi hi naupangte hmuh theih lohna hmunah dah tur a ni . Chu chu a pawimawh hle.

• Tablet te hi room temperature, 15 leh 30 degree Celsius (59 leh 86 degree Fahrenheit) inkar ah dah tur a ni.
• Moisture lakah venghim rawh. Chumi awmzia chu bathroom ang chi hmun hnim ah dah suh tihna a ni.
• Bottle chu khar nghet takin dah la.
• Damdawi expired hman loh tur. Anni chu paih bo rawh.

He leaflet hi a tawi zawng chauh a ni. Thu hriat zawng zawng a keng tel lo mai thei. He damdawi chungchanga zawhna dang i neih chuan i doctor, pharmacist, emaw healthcare professional emaw nen inbia ang che.

Take-Home Thuchah: 1.1.

Okay, chuvangin, Imatinib chungchang kan sawi tawh atang chuan thil tlemte i hriat reng tur a awm :

• Imatinib hi damdawi bik a ni a, cancer cells te tihpunna tur a titawp thei a ni. I doctor-in a tih ang chiah chiah, a hun takah, a zat dik takah ei rawh.
• Chaw leh tui tam tak nen la rawh. Grapefruit tui nen chuan engtikah mah.
• I doctor hnenah damdawi dang i ei zawng zawng leh i damdawi lam dinhmun zawng zawng hrilh rawh . Hei hi naupai, nau pai tum emaw, nau hnute i pek emaw a nih chuan a pawimawh hle.
• Thisen test neih reng a ngai dawn a ni. Vun inthlak danglam te, natna kai chhinchhiahna te, leh thisen chhuah dan danglam tak te hi fimkhur rawh. Chutiang thil i hriat chuan , i doctor hnenah hrilh nghal rawh.
• Damdawi i ei tam lutuk emaw, chaw ei loh emaw a nih chuan engtin nge i tih ang tih pawh kan sawi dun a ni lawm ni? Chu thilte chu hre reng ang che.
• He damdawi hi naupangte hmuh theih lohna hmun lum leh vawt takah dah tur a ni.

Cancer do hi thil awlsam a ni lo. Mahse hetiang damdawi changkang tak tak hmang hian, doctor thupek uluk taka zawm chuan he indonaah hian hnehna chang turin chakna nasa tak i nei ang. Eng harsatna pawh nei ila, Doctor biak pawh hlau suh. Dam leh thuai turin duhsakna kan hlan e!

` imatinib, gleevec, cancer, leukemia, GIST, damdawi, side effects te pawh a awm thei