Inotersen Injection for Neurological Disorders: A chungchang hi i hre chiang ang u

Nangmah emaw i chhungte zingah emaw hian hATTR tih hming pu genetic condition hmuh tur awm lo tak i nei em? I doctor chuan Inotersen tih vaccine chu a vaccine avanga thluak lama harsatna awmte enkawlna atan a pe che em? Chuvangin vawiinah hian he damdawi hi chiang takin kan sawi dawn a, a hman dan tur leh kan fimkhur tur thilte kan sawi dawn a ni. Hei hi damdawi buaithlak deuh a nih avangin hriatthiamna tha tak neih a pawimawh hle.

He damdawi hi eng nge Inotersen an tih?

A awlsam zawngin sawi ila, Inotersen hi damdawi a ni a, damlote nerve chhiatna enkawlna atana hman thin, genetic condition bik nei, hereditary transthyretin-mediated amyloidosis (hATTR) . Brand name Tegsedi hmanga hralh a ni tlangpui.

Tunah chuan he hATTR an tih condition hi eng nge a nih kan en ang. Hei hi natna hmuh tur awm lo tak a ni a, genes hmanga thlah khat atanga thlah dangah a kai darh thin. Kan taksa thin (liver)-a siam, transthyretin an tih protein-a inthlak danglamna pangngai lo (abnormal mutations) avang hian he protein hi taksa peng hrang hrangah, a bik takin nervous system-ah a khawlkhawm a, a awm khawm thin. Heng deposit (amyloid deposit) te hian nerve a tichhe thei a, ke ruh a ti na thei a, a na thei a, a chak lo thei bawk a, kal a harsat phah a, thinlung leh kal a tichhe thei bawk.

Chuvangin Inotersen vaccine hian a tih chu chu protein pangngai lo siam chhuah chu a control a, nerve tihchhiat belh zel chu a tihtlem phah a ni. Hei hi natna damdawi ni lo mah se, natna kal zel dan tur, chu chu natna zual zel tur thununna kawngah nasa takin a pui a ni.

He damdawi hi i ei hmaa i doctor hnena i hrilh tur thilte

Inotersen hmanga enkawlna i tan hmain i doctor hnenah i hriselna chanchin kimchang i hrilh hmasa phawt a pawimawh. Hengte chungchang hi hrilh ngei ang che:

• Kidney disease: Kal natna i neih emaw, i vei tawh emaw a nih chuan.
• Thisen lama harsatna: I thisenah red cell, white cell, platelet awm zat tihtlem thei dinhmun i neih chuan. Hei hi a pawimawh hle a, a chhan chu he damdawi hian i platelet count a nghawng thei a ni.
• Allergies: Inotersen, damdawi dang, ei tur, dye dang eng pawh allergy i neih tawh chuan.
• Naupai: Naupai i nih chuan, a nih loh leh nakin lawka naupai i beisei a nih chuan.
• Lactation: Nu i nih chuan i naute hnute pe mek i nih chuan.

Heng thute a\ang hian i doctor chuan he damdawi hi i tan a tha em tih leh enkawlna hun chhunga fimkhur dang i tih tur te chu a rel ang.

Engtin nge damdawi hi ka hman ang?

Hei hi vun hnuaia injection a ni. Kar khatah vawi khat pek thin a ni tlangpui.

• Training: I doctor emaw, trained nurse emaw chuan he vaccine buatsaih dan tur leh in lama inject dan tur chiang takin a kawhhmuh ang che. Ngaihtuah buai suh, vawikhat i thiam tawh chuan a awlsam hle.
• Thupek zawm rawh: Damdawi hi a tih ang chiah chiah, a hun takah ei la, a pek zat aia tam ei ngai suh.
• Needle paih dan: Needle leh syringe hman tawhte chu bawlhhlawh bawmah paih ngai suh. Sharps container bik ah dah tur a ni. I neih loh chuan i doctor emaw damdawi in emaw atangin i la thei ang.
• Overdose: Damdawi i ei tam lutuk nia i hriat chuan hlauthawng suh , Colombo National Hospital-a National Poisons Information Center-ah phone nghal la, a nih loh leh damdawi in hnai ber Emergency Treatment Unit (ETU)-ah kal nghal rawh.
• Dose i miss a nih chuan: Dose i miss a nih chuan i hriatreng veleh ei nghal tur a ni. Mahse i dose leh tur thleng ni hnih aia rei lo a nih chuan missed dose kha skip rawh. Dose dang chu a hun ruatah ei mai rawh. Double dose ei ngai suh.

Damdawi ei laiin side effect awm thei

Damdawi dang ang bawkin Inotersen hian side effect engemaw zat a nei thei a ni. Chung zinga ṭhenkhat chu thil pawi tak a ni thei a, chuvangin fimkhur a pawimawh hle.

He damdawi nena inzawm thei thil dang

Damdawi dang i ei hian Inotersen nen an inzawm thei a, a thatna emaw, a side effect emaw a nghawng thei bawk. Chuvangin i damdawi ei zawng zawng chu i doctor hnenah hrilh la. A bik takin a hnuaia damdawi te hi fimkhur rawh:

• Thisen tithianghlimtu: Damdawi chi hrang hrang warfarin, apixaban, clopidogrel, leh aspirin te. Hengte hi Inotersen nena ei hian thisen chhuah theihna a tipung thei a ni.
• Painkillers (NSAIDs): Damdawi ibuprofen leh naproxen ang chi te. Hengte hian kal (kidney) a nghawng thei a, thisen chhuah theihna a tipung thei bawk.
• Damdawi dang kal (kidney) tichhe thei te chu: antibiotics thenkhat leh diuretics ( zun chhuah tipungtu damdawi) te an ni .
• Vitamin A: He damdawi hi i ei hian i vitamin A level a tlahniam thei. Chuvang chuan Vitamin A tha tawk kan neih a pawimawh hle.I ei leh in leh vitamin te doctor nen sawiho la, a tul chuan vitamin A supplement ei bawk ang che.