I taksa ruhte chu a throb reng em, a tight reng em? Hei hi Isaacs’ Syndrome tia koh natna awm lo tak a ni thei ang em?

A châng chuan i taksa ruhte chu a hrual mai ang maiin i inhria em, a nih loh leh rang takin i taksa ruhte chu a inher chhuak a, a inkhai nghet hle tih i hria em? Heng symptoms te hi a takah chuan puitling zingah a tam hle. A tam zawkah chuan an serious lo. Mahse, a tlem hle a, heng symptoms te hi neurological condition na tak chhinchhiahna a ni thei. Chutiang dinhmun hmuh tur awm lo tak pakhat, vawiin a kan sawi tur chu Isaacs-a syndrome hi a ni.

Isaacs-a Syndrome hi eng nge ni? A awlsam zawngin i hrethiam ang u!

Awle, hei hi eng nge a nih i en ang u. Isaacs’ syndrome hi neuromuscular disorder a awm lo hle a, a awm lo hle. Hemi kawngah hian thil thleng chu kan taksa peripheral nervous system-a nerve te chu a overstimulated ta a ni. Electrical switch on leh off reng reng ang maiin han ngaihtuah teh, kan nerve pawh a tul lovah a thawk chhuak thin. Hei hian taksa ruhte chu automatic-in hna a thawk tan a, kan thunun theih loh phah a ni.

Hetiang natna vei hian taksa ruh (muscle spasms), a hring (cramps), leh a rilru a buai (twitching) a nei fo thin. A châng chuan hei hian kan autonomic nervous system pawh a nghawng thei bawk. Hei hian thawmhnaw a tipung a, heart rate a tidanglam thei bawk.

Hei hi an ti bawk:

• Muscle fiber hnathawh chhunzawm zel syndrome syndrome
• Isaacs-Mertens natna a ni
• Neuromyotonia natna a ni
• Quantal squander natna a ni

Isaacs’ Syndrome hi engtiang chiahin nge a hluar?

Dik tak chuan hei hi thil awm lo tak a ni. Scientist-te pawhin mi engzat nge vei tih chiang takin an sawi thei lo a, a chhan chu tun thlengin khawvel pumah hri kai za tlemte chauh an awm tawh a ni.

Mahse, a hmaa kan sawi tawh ang khan puitlingah chuan taksa ruh natna leh taksa ruh hring (muscle twitching) (a châng chuan fasciculations tia koh) hi a tam hle. A tlangpuiin an hlauhawm lo. Chuvangin Isaacs’ syndrome hi i neih vang mai maia neurological condition na tak a ni tih ngaihtuah hlau suh. Mi tam tak chuan chhan dang, awlsam zawk vangin heng symptoms hi an nei thin.

Isaacs’ Syndrome hi tuin nge vei thei ang?

Isaacs’ syndrome hi kum 15 leh 60 inkar atanga tan a ni tlangpui a, mahse, he natna hi naupang zawk, a chang chuan nausen thlengin an awm tih hmuhchhuah a ni.

He natna hi damdawi lam thil dang thenkhat nen pawh a inzawm thei bawk. Chumi awmzia chu chutiang natna nei te chuan an vei tam zawk tihna a ni. Entirna tlemte chu hetiang hi a ni:

• Ngawt
• Celiac natna a ni
• Chronic inflammatory demyelinating polyneuropathy (CIDP) - Hei hi nerve natna a ni bawk.
• Guillain-Barré natna a ni
• Hashimoto natna a ni
• Lupus a ni
• Myasthenia gravis natna (myasthenia gravis) a ni
• Peripheral neuropathy a awm a
• Rheumatoid arthritis natna a ni
• Thymoma - Hei hi cancer a ni a, thymus gland-ah a lo awm a.
• Vitamin B12 tlakchham vang a ni

He neuromyotonia an tih hi engte nge a chhan?

Hei hi chhan lian tak pahnih a awm thei a, chungte chu:

1. Acquired condition: Hei hi autoimmune condition a ni. A awlsam zawngin kan taksa immune system hian kan cell hrisel tak takte chu hnam dang rawn lut ang maiin a rawn bei tan ta a ni. Isaacs’ syndrome vei zinga 50% vel chuan antibodies an nei a, chu chuan electrolyte potassium chu kan nerve-ah a luh leh chhuah theihna tur channel-te a bei a ni. Hetianga potassium che vel hian nerve hnathawh a nghawng a ni. Heng channel te hi a chhiat chuan nerve te chu a overstimulated thin.

2. Hereditary condition: Hei hi genetic a ni. Chu chu nu leh pa atanga fate rochun a ni tihna a ni.

Isaacs’ Syndrome natna lan chhuah dan chu engte nge ni?

Heng symptoms te hi nitin a awm tlangpui a, mut lai pawhin a awm thei bawk. A tam zawkah chuan taksa ruh natna (muscle cramps) chhinchhiahna hi kut leh keah a langsar ber a ni. Mahse, taksa peng dang pawh a nghawng thei a ni.

A lan chhuah dan tlangpui thenkhat chu hetiang hi a ni:

• Ataxia: Hei hian kea kal emaw, che vel emawa taksa balance leh coordination hloh tihna a ni. Zu rui ang maiin i inher mai thei.
• Lump a lo chhuah theih hun chhung: Lump chu vawi khat a tight tawh chuan a pangngaia a lo kir leh theih nan hun rei tak a ngai thin.
• Thawmhnaw tam lutuk (hyperhidrosis): Chhan awm lova thawk hah lutuk.
• Heart rate inthlak danglamna: Heartbeat chu rang takin a chak emaw, a slow emaw thei .
• Chauhna leh mut theih lohna: Chauhna awm reng leh zan mut theih loh.
• Sa rolling, tightening, throbbing, leh weakening: Hengte hi hun kal zelah a pung zauh zauh thin.
• Myokymia: Hei hi taksa ruhte a inher chhunzawm zel, a inher chhunzawm zel emaw, a inher chhuak reng emaw hriatna a ni. Ṭhenkhat chuan "vun hnuaia rulhut hrual ang mai" tiin an sawi.
• Thusawi emaw thawk harsa emaw, kawr chhunga tonsils te a nghawng chuan.

Ngaihtuah teh, i ding reng lai pawhin i kut emaw, i ke emawa sa hring pakhat chu a chhunga thil pakhat a inher ang maiin a inher reng a ni. Zana i mut lai pawhin hei hi a tawp lo a nih chuan engtiang chiahin nge a ti thinrim ang? Chu chu myokymia chu a ni.

Engtin nge Isaacs’ Syndrome hi an hriat theih?

I doctor chuan Isaacs’ syndrome finfiah nan leh natna dang a awm loh nan test thenkhat a ti thei bawk. Chung zinga ṭhenkhat chu:

• Thisen test: Hengte hian Isaacs’ syndrome vei zinga a chanve vel thisenah antibody chi hrang hrang hriat theihna a pui a ni.
• Nerve conduction study leh electromyograms (EMG): Heng test te hian i taksa ruh leh nerve te hnathawh dan a teh a, electrician-in wire chhunga current a check ang mai a ni.
• Imaging study CT scan emaw MRI scan emaw: Hengte hian taksa chhungril lam a en thei a, harsatna dang a awm leh awm loh a en thei.

A châng chuan, Isaacs-a syndrome hi natna dang stiff person syndrome , rippling muscle syndrome , emaw cramp-fasciculation syndrome te nen pawh a inthlau thei a, chuvangin diagnosis dik tak neih a pawimawh hle.

Isaacs’ Syndrome hi engtin nge enkawl a nih?

Tunah hian he natna hi damdawi a la awm lo. Enkawlna hian i natna lan chhuah dan control leh a theih ang anga i hnathawh that theihna tura puih a tum ber a ni.

Isaacs’ syndrome hi autoimmune disease dang emaw malignancy emaw nena inzawm a nih chuan a hnuaia awm chu enkawl a pawimawh bawk.

I doctor chuan Isaacs’ syndrome hi a hnuaia damdawi te hi a rawn rawt thei ang:

• Anticonvulsant damdawi: Entirnan, phenytoin leh carbamazepine ang chi damdawi te. Chungte chuan taksa ruh (muscle spasms), khur leh natna te a tiziaawm a ni.
• Immunosuppressive medications: Damdawi azathioprine leh methotrexate te hian immune system chu a dik lo taka a che lo turin a control a ni.
• Intravenous immunoglobulin (IVIG): Hei hian donor hrisel tak tak atanga antibodies awmna solution chu vein kaltlangin taksaah pek a ni.
• Corticosteroid ei tur: Entirnan, prednisolone.
• Plasma inthlak danglamna:Hei hi antibodies pangngai lo nei te thisen atanga toxins leh chutiang antibody tha lo te filter chhuah dan a ni.

Isaacs-a Syndrome hi a veng thei ang em?

Scientist-te hian hei hi eng thil nge a thlen tih an la hre chiang lo a, tun dinhmunah chuan ven dan tur a awm lo.

Neuromyotonia vei te tan engtin nge an hmalam hun?

Isaacs’ syndrome vei tan chuan hmalam hun a inang lo. Chu chu natna nasat dan, a chhan bulpui, enkawlna hlawhtlinna leh a kaihhnawih damdawi lam thil dangteah a innghat a ni.

Neuromyotonia symptoms hi hun kal zelah a na zual sauh sauh a. An chetna nasa takin an tihtlem thei a, nitin hnathawhnaah pawh an tibuai thei bawk.

Chumi awmzia chu a tir lama taksa peng hrang hrang (muscle spasm) te tak te anga lang chu a hnuah chuan a nasat em avangin kal theih loh khawpin a na thei tihna a ni. Chuvangin natna hi hriat hmasak a, enkawl tan a pawimawh.

Tunah hian tihdamna famkim awm lo mah se, he natna hi a tlangpuiin thihna thlen thei a ni lo.

Isaacs’ Syndrome natna vei tha turin eng nge ka tih ang?

Hetiang dinhmun nena nun hi thil harsa tak a ni thei a, mahse mi thenkhat chuan a hnuaia thil tih hian taksa leh rilru lama nghawng a neihte enkawl kawngah hlawhtlinna an hmu a ni:

• Neuromuscular disorder nei te tana thurawn pek: awareness programme-a tel leh midangte he thil chungchanga zirtirna pek.
• Counselling session-a tel: Hetiang dinhmun hi rilru lama hmachhawn dan tur ruahmanna tulte i zir thei ang.
• Chutiang dinhmuna ding midangte nena inzawmna siam: A bik takin social media kaltlangin. Mahni chauh ni lo anga inhriat hi chakna ropui tak a ni.
• Ngaihtuah thiam.
• Yoga tih dan tur.
• Kea kal: A theih ang anga taksa chak taka awm reng a pawimawh.

Isaacs’ Syndrome chungchang hi ka doctor hnenah eng nge zawh belh theih ang?

Neuromyotonia emaw Isaacs’ syndrome emaw i vei nia hriat i nih chuan i doctor hnenah heng zawhnate hi zawt ngei ang che:

• Engvangin nge Isaacs’ syndrome hi ka neih?
• Hemi nena inzawm damdawi lam harsatna dang ka nei em?
• Engtin nge hei hi Isaacs-a syndrome a ni a, ALS (Amyotrophic Lateral Sclerosis) ang neuromuscular natna dang a ni lo tih chiang taka kan hriat theih ang?
• Hei hian ka taksa hmun engte nge a nghawng?
• Eng enkawlna nge i rawt?
• Clinical trial eng emaw zat neih theih ka ni em?
• Physics therapy emaw occupational therapy emaw hian min pui dawn em?
• Hetiang dinhmun ka hmachhawn theih nan counselor emaw support group emaw hnenah min refer thei ang em?
• Ka chhungte zingah hian Isaacs’ syndrome test neih a ngai em?

A tawp berah chuan hriat reng tur (Take-Home Message) .

Isaacs’ syndrome hi neuromuscular disorder hmuh tur awm lo tak a ni a, nerve leh muscle te chu a thawk nasa lutuk a ni. Hetiang natna hi i vei tih hmuhchhuah a nih chuan hlau suh, mahse i doctor nen inbia ngei ang che. Amah hian a kaihhnawih natna dang a enfiah thei a, taksa ruh inthlak leh nghet lo ang chi symptoms te enkawl turin a pui thei bawk. Enkawlna dik leh puihna dik tak i neih chuan he natna nen hian nun tha tak i hmang thei tih hre reng ang che.

Isaacs ' syndrome, neuromyotonia, taksa ruh na, taksa ruh natna, thluak lam natna