Thisen cell chi thum zawng zawng hi i hniam em? Pancytopenia chungchang hi han sawi ila!

A châng chuan i chau reng em? A nih loh leh thil tlemte chauhvin i na a, i taksa pum puiah hliam i hmu em? Chûngte chu i thisenah inthlâk danglamna engemaw zât avânga lo awm thei a ni. Vawiin hian hetiang huna lo awm thei dinhmun kan sawi dawn a, chu chu doctor-te chuan "pancytopenia" an ti a ni. Ngaihtuah buai suh, he thu hi awlsam takin kan sawi dawn a ni.

Pancytopenia tih hi eng nge ni?

A awlsam zawngin, pancytopenia hi kan taksaa thisen cell chi hrang pathum – red blood cells, white blood cells, leh platelets – te hi a tlangpui aia hniam vek a ni. Factory lian tak ang maiin han ngaihtuah teh. He factory-ah hian hna hrang hrang thawk tur hnathawk hrang hrang an awm a. Chutiang bawkin heng thisen cell te pawh hi. Type tin hian hna bik an nei vek a.

Tunah chuan heng cell chi hrang hrangte hi a tlahniam chuan eng nge thleng tih hi han en teh:

• Thisen sen (red blood cells) tlahniam: Hei hi kan taksa pum puia oxygen phurtu cell te an ni. Heng cell ah hian protein bik hemoglobin tih a awm a . Chu chu oxygen chu a vawng tlat a ni. Chuvangin, thisen sen emaw hemoglobin emaw a tlahniam chuan "anemia" emaw "thisen tlakchhamna" emaw kan ti thin.
• White blood cell count: Thisen var, a nih loh leh leukocyte te hi taksa invenna cell ang a ni. Natna hrik an do a, natna lakah min venghim a ni. Heng white cell zingah hian a tam ber chi chu neutrophils an ti a. Thisen var tlahniam chu leukopenia an ti a . Neutrophils tlahniam hi neutropenia an ti bawk .
• Platelet count hniam: Platelet hi cell fragment te tak te a ni. Mahse hna ropui tak an thawk a ni. Cut kan neih hian heng platelet te hian thisen chhuah tihtawp nan a pui thin. Thisen zawrh nan an pawimawh hle. Chuvângin, platelet count a tlem chuan, chu natna chu thrombocytopenia an ti a ni.

Pancytopenia i neih chuan i thisen cell hniam dan azirin heng natna pakhat, engemaw zat emaw, a zawng zawng emaw avanga symptoms i nei thei a ni.

Pancytopenia hi engtiang chiahin nge a awm?

Dik tak chuan pancytopenia an tih hi i ngaihtuah angin a awm lo. A chhan awm thei tam tak a awm avangin mi engzat nge vei tih chiang taka sawi a harsa hle.

Pancytopenia natna lan chhuahna chu engte nge ni?

A chang chuan pancytopenia hi a na lo thei hle. Symptom lian tak tak i hmu lo mai thei. A châng chuan, doctor chuan thisen hnathawh pangngai an tih hian a hmu ang. Mahse, he natna hi a nasat em em a, nunna atana hlauhawm tak a nih theih hun a awm. Chutiang hunah chuan inenkawlna zawng nghal tur a ni.

Tunah chuan heng thisen cell chi hrang hrang a tlahniam hian eng symptom hrang hrang nge awm tih i lo en ang u.

Thisen zam (red blood cells) tlahniam (anemia) chhinchhiahna .

Thisen sen (red blood cells) i neih tlem chuan i taksa peng dang leh tissue te hian oxygen an dawng tlem hle ang. Symptoms i nei thei ang:

• Chau tih hriat reng (Fatigue): Chau leh engmah tih duh lo anga inhriatna.
• Thâwk harsa (dyspnea): Thawhrimna tlemte pawh nise thawk harsa tih.
• Lung a na hle tih a hriat.
• Lu na.
• Arrhythmia hi thinlung a thawk chak emaw, a thawk mumal lo emaw tih hriatna a ni.
• Vun dum emaw, vawt, thawmhnaw hring emaw.

Thisen var tlahniam (leukopenia) chhinchhiahna .

Thisen var (white blood cells) i neih tlem chuan i taksain natna a do theihna a tlahniam a. Hei hian awlsam takin infection i kai thei tihna a ni. Heng natna hrik te hian symptoms a thlen thei a, chungte chu:

• Chau tih hriat reng (Fatigue).
• Khawsik leh khawsik.
• Thlarau na emaw, natna hrik (pharyngitis) emaw a awm thei.
• Kawngkhar natna.
• Khuh a tam hle.
• Kawthalo.
• Thâwk harsa.
• Lymph node a lo hring chhuak.
• Cuts atanga pus chhuak.

Platelet count tlahniam (thrombocytopenia) chhinchhiahna .

I platelet a hniam chuan i thisen a clot tha lo. Hei hian hetiang hi a thlen thei a ni:

• Thil tenawm ber atang pawhin i taksaah hliam i tuar.
• Thisen chhuah tihtawp harsa emaw, rei tak daih emaw.
• Hmeichhiaah thlasik laiin thisen chhuah tam lutuk.
• Thisen chhuahna chu bawlhhlawh, zun , emaw, riltam emaw hmanga chhuak.
• Vunah sen emaw, sen emaw (petechiae) – vun rawng ang chi. A châng chuan a sen, a sen, a sen (purpura) emaw pawh a lo lang thei bawk.

Eng thilin nge he pancytopenia natna hi a thlen?

Pancytopenia hi kan ruhro a thisen cell siam chhuah dan dik lo vang a ni tlangpui . Kan thisen cell te hi ruhro (bone marrow) ah siam chhuah a ni tih i hria em? Hetiang kalphung hi hematopoiesis an ti a . Heng cell te hian ruhro atanga chhuakin kan thisenah an puitlin hnuah chauh an lut thin.

Chuvangin, i ruhro hian thisen cell hrisel a siam tling lo a nih chuan, emaw, heng thisen cell te hi siam chhuah a nih hnua a chhe rang lutuk a nih chuan pancytopenia hi a lo awm thei a ni.

Heng thisen cell siam chhuahna tibuaitu emaw, tichhe thei emaw thil engemaw zat a awm a:

• Bone marrow nena inzawm natna: 1.1.Natna thenkhat, ruhro (bone marrow) atanga thisen cell pangngai lo siam chhuah tir thin a awm a. Chung zinga a tam zawk chu kan dam chhunga `acquired` a ni. Ṭhenkhat chu `rochun` an ni. Entir nan:
• Aplastic thisen tlakchhamna (anemia) a awm
• Fanconi thisen tlakchhamna (anemia) a awm
• Diamond-Blackfan thisen tlakchhamna

• Cancer: Cancer cells te chu ruhro (bone marrow)-a an darh chuan thisen cell hrisel siam chhuahna a tibuai a ni. Cancer chi hrang hrang, pancytopenia thlen thei te chu:
• Leukemia natna (Leukemia) a ni
• Lymphoma natna (Lymphoma) a ni
• Multiple myeloma a awm thei
• Myelofibrosis natna (Myelofibrosis) a awm
• Myelodysplastic syndromes te hi a awm a
• Hmun dang atanga ruhro (metastatic cancer) thlenga cancer darh zel .

• Nutritional deficiencies leh zu hman: I taksain vitamin B12 leh folate ang chi nutrients a dawng tlem chuan thisen cell hrisel a siam thei lo mai thei. Tin, zu in tam lutuk hi pancytopenia thlentu lian tak a ni thei bawk.

• Natna hrik kai: He natna hi virus chi hrang hrang avanga lo awm thei a ni bawk. Entirnan:
• Mononucleosis `(Mononucleosis - mono)` tih a ni
• HIV (mihring taksa chak lohna hrik) .
• Hepatitis C natna a ni
• Parvovirus B19 `(Parvovirus B19)` tih hi a ni
• Tuberculosis natna a ni
• Malaria natna a awm

• Autoimmune conditions: Hei hi i taksaa immune cells ngeiin thisen cell hrisel tak takte a beih hun a ni. Autoimmune natna, pancytopenia thlen thei te chu:
• Lupus a ni
• Rheumatoid arthritis natna a ni

• Damdawi hmanga enkawl dan: Damdawi thenkhat, a bik takin cancer damdawi chemotherapy te hian thisen cell siam chhuah a ti tlem thei hle.

• Toxins nena inzawmna: Environmental toxins benzene leh arsenic te hian i thisen cell te a tichhe thei a ni. Radiation exposure hian i thisen cell a ti tlem thei bawk.

• Splenic sequestration tih hi a awm lo.Damdawi lam thil thenkhatah chuan i rilruah thisen cell a awm khawm thei a. Autoimmune natna, thin (liver cirrhosis) leh cancer thenkhat te hian hetiang hi a thlen thei a ni. Chutiang a nih chuan ril chu a lo hring thei a, a na thei bawk (splenomegaly).

A tlem berah chuan doctor-te chuan he thisen cell tlahniam chhan dik tak hi an hmu thei lo. Hei hi idiopathic pancytopenia an ti a .

Tute nge pancytopenia vei theihna chance sang zawk?

Kan sawi tawh ang chi natna nei tu pawh hian pancytopenia an nei thei. Amaherawhchu, i chhungkuaa mi tu emaw chuan thisen lama harsatna a neih chuan, emaw, thisen cell siam chhuahna tichhe thei chemotherapy i dawng a nih chuan, he natna hi i nei tam zawk a ni.

Engtin nge pancytopenia hi an hriat theih?

Routine complete blood count (CBC) hian thisen cell a hniam leh awm loh a enfiah thei a ni. Heng value te hi kum, hnam leh hriselna dinhmun a zirin a danglam deuh thei a ni.

Hengte hi a tlangpuiin hniam anga ngaih level te chu an ni:

• Thisen sen (red blood cells): Hmeichhia tan chuan thisen microliter khatah cell maktaduai 4.2 aia tlem emaw, hemoglobin gram 12 (g) aia tlem emaw (deciliter khatah). Mipa tan chuan thisen microliter khatah cell maktaduai 4.7 aia tlem emaw, hemoglobin gram 13 aia tlem (deciliter khatah) emaw a ni.
• Thisen var: Thisen microliter khatah thisen var 4,000 aia tlem lo, a nih loh leh thisen microliter khatah neutrophil 1,800 aia tlem lo. Neutrophils hi thisen var chi khat a tam ber a, chuvangin he count hi a pawimawh hle.
• Platelets: Thisen microliter khatah platelet 150,000 aia tlem lo.

A chhan hriat tumin eng test dang nge tih a nih?

I doctor-in pancytopenia i vei tih a hriat chuan eng thil nge a thlen tih hriat tumin test engemaw zat an ti leh mai thei. Thisen natna lama thiamna nei doctor (hematologist) pawh i pan a ngai mai thei bawk .

Heng test-ah hian:

• Peripheral blood smear: He test hian i thisen cell te chu microscope hmangin a enfiah thin. Cell pianzia danglam tak tak a awm chuan a chhan hriat theihna a pe thei a ni.
• Vitamin B12 leh folate level test: Pancytopenia hi ei leh in lama harsatna avanga lo awm a ni tlangpui bawk. Chuvangin heng level te hi check hian chu chu a chhan a ni em tih hriat theih nan a pui thei a ni.
• Bone marrow aspiration leh biopsy: Hetiang tih danah hian doctor chuan i ruhro sample te tak te a la a, pancytopenia thlentu natna, cancer ang chi a awm leh awm loh a test thin.

I test result, medical history leh symptoms a zirin i doctor hian hetiang test hi a ti thei bawk a, a chhan dang zawng turin:

• Virus test neih a ni.
• Infection awm leh awm loh test thin.
• Autoimmune condition awm leh awm loh test.
• Genetic mutations (i DNA inthlak danglamna) test.

Engtin nge pancytopenia hi enkawl a nih?

Enkawlna hi a bulpui ber zawn chhuah, enkawl leh a lan chhuah dan tihtlem hi a ni ber. I thisen cell count direct-a tihpun theihna tur enkawlna pawh a awm bawk. Chung zingah chuan:

• Damdawi: Damdawi thenkhat chu ruhro tichaktu leh thisen cell tam zawk siam tura puitu a awm.
• Thisen pek: I thisen cell zat a tlem lutuk a, i hriselna a tichhe thei a nih chuan thisen sen emaw platelet emaw infusion i pe thei a ni.
• Stem cell emaw bone marrow transplant: Heng tih danah hian stem cells thawk tha lo (hengte hi bone marrow-a thisen cell siamtu cell bulpui te an ni) tihbo a, stem cell hrisel tak tak thlak a ni.

I neutrophil level a hniam hle a, natna kai theihna a sang hle a nih chuan broad-spectrum antibiotics pek i ni thei bawk .

Pancytopenia vei chuan eng nge a beisei ang?

I dam theihna chance chu thisen cell tlahniam chhanah a innghat a ni. Tunah hian pancytopenia enkawlna hlawhtlinna chungchangah hian data chiang tak a la awm lo. Chu ai chuan, zirchiangtute chuan a hnuaia natna awmte tana enkawlnate chu eng angin nge a hlawk tih an en zawk a ni.

A pawimawh ber chu, a hnuaia awmte enkawlna a \ha chhoh zel chuan pancytopenia vei te tan pawh a rah chhuah pawh a \ha chho zel a ni. Hemi chungchang hi doctor nen inbiak a pawimawh hle. Research information thar ber berte a hrilh thei che a, i dinhmun a nghawng dan pawh a sawifiah thei bawk.

Pancytopenia hi natna khirh tak a ni em?

Ni e, a pawi hle thei. I thisen cell tlahniam chhanah pawh a innghat bawk. Pancytopenia i vei chuan i doctor chuan a chhan a zawng ang a, a nasat zia a hre ang.

Engtikah nge damdawi in (ETU) ah a rang thei ang bera ka kal ang?

Pancytopenia hi enkawl loh chuan a na hle thei a, nunna atana hlauhawm tak a ni thei bawk. Heng symptoms te hi i neih chuan emergency room (ETU) ah kal nghal rawh:

• Khawsik hi 101 degree Fahrenheit (38 degree Celsius) aia sang a nih chuan.
• I hriatna i hloh chuan (blacking out).
• Thâwk harsatna nasa tak i neih chuan.
• Buaina thut.
• Lu na thar i neih tan chuan.
• Thisen chhuak nasa tak a awm chuan.
• I rilru natna i neih chuan.
• Seizure a awm chuan.

Pancytopenia hian kawng hrang hrangin a nghawng thei che a ni. I thisen cell hniam zia leh a chhan bulpui ber chu eng nge ni tih ah a innghat. I thisen cell count hian thisen tlakchhamna, natna hrik kai emaw, thisen chhuah tam lutuk emaw hlauhawmna a siam che a nih chuan i doctor thupek chu uluk takin zawm rawh. Tin, doctor pan tur a nihzia tilang thei symptoms awm thei te pawh zawt bawk ang che.

A tawp berah chuan thil hriat reng tur (Take-Home Message) .

Chuvangin, tunah chuan pancytopenia hi kan thisen cell pathum, red cells, white cells, leh platelets te chu vawi khata tihtlem vek theihna dinhmun a ni tih i hrethiam tawh mai thei. Hei hi chhan tam tak a awm thei a, a lan chhuah dan pawh a inang lo hle.

A pawimawh ber chu heng symptoms te hi i neih chuan doctor pan a ni. Chumi hnuah chuan thil dik lo chu a hmuchhuak thei a, i mamawh enkawlna chu a tan thei ang. I man hma chuan heng dinhmunte hi i enkawl tha thei fo thin. Chuvangin, i taksa hi enkawl la, thil danglam i hriat chuan ngaihven rawh. Hrisel takin awm rawh!

` Pancytopenia, Pancytopenia, Thisen cell tlakchhamna, Thisen sen, Thisen var, Platelets, Bone marrow, Anemia, Leukopenia, Thrombocytopenia