I thisen a lum em? Polycythemia Vera (PV) chungchang hi a awlsam zawngin i zir ang u

Chhan awm lovin i lu a buai fo em? I chau hlein i hria em? A bik takin tui lum taka inbual hnuah tuar theih loh khawpin i itch em? I beng bulah ri ri i hre em? Heng thilte hi thil pangngaiah kan ngai a, kan ngaihthah fo thin. Mahse, a châng chuan, heng chhinchhiahna tenau tak takte hnung lamah hian kan hriat tam loh leh kan ngaihtuah tûr dinhmun a awm thei a ni. Vawiin hian chutiang natna pakhat chungchang kan sawi dawn a ni. Chu chu Polycythemia Vera , a tawi zawngin PV a ni.

A awlsam zawngin sawi ila, polycythemia vera (PV) hi eng nge ni?

A awlsam zawngin sawi ila, polycythemia vera (PV) hi kan taksaa thisen natna a ni. Kan taksaah thisen sen tam lutuk a siam chhuak thin . Tunah chuan, "Red blood cells hi taksa tan a tha a, chuti a nih chuan kan siam tam lutuk hian eng nge thleng ang?" Chu chu buaina chu a ni.

Lirthei engemaw zat phur thei kawngpui a awm ang tih han ngaihtuah teh. Chu kawngpuiah chuan a phurh theih aia tam lirthei i dah chuan eng nge thleng ang? Kawngpui pumpui chu a inkhar vek ang a, lirthei te pawh an kal thei lo ang, a dik em? Chu chu kan thisen kalna kawng chhungah a thleng thin. Thisen sen a tam lutuk chuan kan thisen a thim . Tui ni tur thil chu khawizu ang maiin a thick ang bawkin.

Hetianga thisen thicking hian thisen a ti zawi hle a ni. Hei hian thisen zam a tipung a ni . He thisen zam hi thinlung lamah a kal chuan heart attack a thlen thei a, thluaka a kal chuan stroke a thlen thei bawk. Chu mai pawh ni lovin, natna tibuaitu, beng ri reng, pum na, hnar thisen, leh mit hmuh lohna te pawh a thlen thei bawk.

Hei hi cancer tak tak a ni em? Ka lungngai tur em ni?

He zawhna hi mi tam takin an neih a ni. Ni e, polycythemia vera hi thisen cancer chi khat a ni. Damdawi lamah chuan Myeloproliferative Neoplasm (MPN) kan ti a.

Tunah chuan "cancer" tih thumal kan hriat hian kan hlauthawng hle. Chu chu thil pangngai a ni. Mahse cancer zawng zawng hi a inang vek lo tih kan hriatthiam a ngai. Ṭhenkhat chu an thang chak hle a, an chetsual hle bawk. Mahse PV hi cancer chi khat , a lo thang chak lo hle . Chu chu vawi khatah a aggressive lo tihna a ni. A tam zawkah chuan he natna hi kum 60 an tlin hnuah hmuhchhuah a ni.

He natna avanga thih ai chuan, a hmaa kan sawi tawh ang khan thisen zam avanga heart attack leh stroke ang chi harsatna avang hian a hlauhawm zawk a ni. Tin, a tlem hle bawk a, he natna hi thisen cancer chi dang na takah a chang thei bawk. Mahse chu chu percentage tlemteah a thleng thin. Chuvangin, "cancer" tia sawi ni mah se, hei hi enkawlna dik tak hmanga enkawl tha thei dinhmun a ni.

He natna hian engtin nge kan taksa a nghawng a, eng nge a hlauhawmna?

Tunah hian he thisen sen pung hian kan taksa peng hrang hrang a nghawng dan hi i lo en ang u.

• Thisen zam: Hei hi harsatna lian ber a ni. Thisen a tlak chuan thisen pump turin thinlung hian nasa zawkin hna a thawk a ngai a ni. Tin, taksa kalna kawng nalh tak tak kal tlanga thisen kal chu a tlahniam bawk. Hei hian kan taksa peng leh taksa peng hrang hrangte hian oxygen an dawng tlem zawk tihna a ni .
• Spleen Overwork: Kan taksa peng pakhat, spleen an tih hian thisen cell hlui, chhiat tawhte filter chhuah hi a ni. Tunah chuan thisen sen tam tak siam chhuah a nih chuan spleen chu a overload ta a ni. Filter pakhat hmanga bawlhhlawh tam tak filter tum a, a khar ang mai a ni. Hei hian spleen a ti na thei a ni. Splenomegaly kan ti a ni . Tichuan i pum veilam lamah rit leh na i nei thei ang.

He PV natna hlauhawmna leh harsatna lian ber berte chu eng nge ni thei tih hriat nan a hnuaia table hi han en ila.

He natna hi engte nge ni?

PV hi a tlangpuiin stage engemaw zat chhungin zawi zawiin a lo thang lian thin.

1. Early PV: Hetiang dinhmunah hian mi tam zawk chuan symptom an nei lo tak tak . A nih loh leh symptom na lo tak tak, luak chhuak leh hahna ang chi chauh an nei bawk. A châng chuan thisen test a nih chuan natna dang a awm leh awm loh enfiah a nih pawhin a lo lang chhuak ṭhin.

2. Advancing PV: Hun kal zelah symptoms a pung zauh zauh. Hetih lai hian natna lan chhuah dan, rilru hahna, taksa rihna tlahniam, leh pum chhunga natna (abdominal discomfort) te hi a awm thei a, chu chu spleen lian lutuk vang a ni.

3. A tawp ber ("Spent Phase"): Hei hi a buaithlak deuh. Kum tam tak hnuah natna thlentu cell pangngai lo tak takte chu kan ruhroah a darh vek a, ruhro chu a tichhe ta a ni. Ruhro (bone marrow) hi kan thisen cell siamna factory ang a ni. He factory hi a chhiat chuan a chhungah scar tissue a lo awm thin. Tichuan, thisen hrisel siam theih a ni lo. Mak tak maiin, thisen sen tam lutuk siam chhuah atanga lo chhuak natna hian a tawpah chuan thisen sen awm tlem lohna dinhmun a thlen a, chu chu thisen tlakchhamna (anemia) a ni .

Eng symptoms nge hriat theih?

PV symptoms hi hun kal zelah zawi zawiin a lo lang fo thin. Mi thenkhat chu kum tam tak chhung chu symptom nei lovin an kal thei. Heng symptoms te hi eng nge ni tih han thlir ila.

Engvangin nge hetiang hi a lo awm? Eng nge a chhan?

Hei hi a chhan ber chu kan ruhro (bone marrow)-a stem cell-a gene mutation vang a ni. Computer program-a code line khat a kal sual ang mai a ni. Tichuan program pumpui chu a kal ta vek a ni.

Kan thisen cell te hi thang lian tura hrilhtu gene a awm a. PV vei zinga 90% aia tam chuan JAK2 tih gene-ah mutation an nei a. He thupek dik lo avang hian ruhro hian thupek a dawng a, "Thisen sen siam zel rawh, titawp suh." Chuvangin thisen sen (red blood cells) chu thunun theih lohvin siam chhuah a ni.

Engtin nge doctor hian he natna hi dik taka a hriat theih ang?

Heng symptoms te hi i neih chuan i doctor chuan i symptoms te a zawt hmasa ang che. Tichuan test engemaw zat an nei ang a, an diagnosis chu an finfiah ang. World Health Organization (WHO) chhinchhiah dan chuan PV hriat theihna tur hian criteria pathum zawm a ngai a ni.

1. Thisen Test: Hei hi test hmasa ber leh pawimawh ber a ni. I red blood cell count a sang lutuk em tih a enfiah thin.

• Hemoglobin level sang tak a awm.
• Hematocrit (thisen chhunga red cell awm zat) a pung.

2. Bone Marrow Biopsy: Hip ruh atang hian ruhro sample te tak te tak tak lak a ni a, microscope hmangin ruhroah hian cell pangngai lo a awm em tih enfiah a ni.

3. Genetic test emaw hormone level emaw: 1.1.

• JAK2 gene mutation awm leh awm loh enfiah nan genetic test an nei a .
• A nih loh leh, kal atanga siam hormone erythropoietin (EPO) level an en thin. He hormone hian ruhro (bone marrow) chu thisen sen (red blood cells) siam turin signal a pe a. PV-ah chuan taksain he hormone hi a siam chhuak tawh lo a, a chhan chu thisen sen (red blood cells) chu mahni chauha siam chhuah a nih vang a ni. Chuvang chuan EPO level a hniam hle.

Hei hi eng enkawlna nge ni?

PV enkawlna kawngah hian tum lian tak pahnih a awm a. Pakhat chu thisen zam hlauhawmna tihziaawmna tur a ni a, pakhat zawk chu natna lanchhuahna tibuaitu control nan a ni.

• Phlebotomy - Thisen lakchhuah: Hei hi a hman tlanglawn ber leh a awlsam ber a ni. Thisen pek ang bawkin, thisen tlemte (a tlangpuiin pint khat vel) chu i taksa atangin a hun takah lakchhuah a ni . Hei hian i thisen density leh red blood cells a tihtlem thei a ni.
• Aspirin tlem: I doctor chuan thisen zam a veng loh nan nitin aspirin pill tlemte ei turin a rawt mai thei. Mahse, pumpui ulcer ang chi harsatna i neih chuan hei hi a dik lo mai thei.
• Red blood cell tihziaawmna damdawi: Natna a nasat chuan emaw, thisen pek ringawt pawh a tawk lo a nih chuan red blood cell siam chhuah tlem thei damdawi pek a ni. Entirnan hydroxyurea leh interferon alfa te hi a ni.
• Itching enkawl dan: Itching na tak control nan antihistamine emaw damdawi bik dang emaw pek theih a ni.

Engtin nge he natna hi ka nunpui theih ang?

He natna hi i vei tih i hriat veleh, he natna nena nunpui tur hian i tih theih tam tak a awm.

• Doctor hmu fo rawh: A hun takah clinic-ah kal la, thisen test tir rawh. I doctor-in i dinhmun a enfiah a pawimawh hle.
• Exercise: Exercise tlem lutuk hian thisen kal tha a awm theih nan a pui thei a ni.
• Meizial zuk loh: Meizial in hian thisen kalna kawng a ti zim a, chu chuan thisen zam a tipung a ni.
• Oxygen level hniamna environment pumpelh rawh: Tlang chhip ang chi hmun sang takah chuan oxygen level hniam a awm. Chutiang hmuna kal chu pumpelh rawh.
• Thisen sang control: Taksa rihna hrisel vawn reng hian thisen sang control nan a pui thei a ni.
• Tui in tam: Dehydration hian thisen zam a tipung thei. Chuvangin nilengin tui tam tak in tur a ni.

PV hi cancer ni mah se, mi tam tak chu he natna an vei tih hmuhchhuah a nih hnuah kum sawm tam tak chhung chu an dam tha hle. Hlauhawm ber chu thisen zam avanga harsatna thleng a ni a, cancer ngei a ni lo. Chuvangin doctor nena inlaichinna mumal tak neih leh nunphung hrisel zawm hi he natna hi damdawi in enkawl ang bawkin a pawimawh a ni.