He aha te Whakatō Pūtau Take Allogeneic? Kia mārama tātou ki tēnei!

E mōhio ana tātou katoa ki te wehi me te manukanuka e puta mai ana i te rongonga mai i te tākuta kei te pāngia tetahi mema o te whānau, tetahi hoa rānei e te mate toto nui, te mate pukupuku toto rānei. Engari nā te whanaketanga o te rongoā i ēnei rā, kei reira ngā maimoatanga kaha hei whakaora i aua mate. Ko tētahi o aua maimoatanga whakaora ora ko te "Allogeneic Stem Cell Transplant." Ahakoa he ahua uaua te ingoa, me kōrero tātou mō ngā mea ka puta i roto i tēnei tuhinga .

He aha rawa te tikanga o te whakawhitinga pūtau take allogeneic?

Ki te whakarapopototanga, ko te tango i ngā pūtau take mate, kore mahi pai i roto i tō tinana, ka whakakapi i aua pūtau take ki ngā pūtau take hauora, hototahi mai i tētahi atu tangata (he kaituku).

Nā, me whakamārama ake tātou i tēnei.

• Ngā Pūtau Taketake: Ka taea hoki e tātou te kī ko ēnei he "pūtau whaea" nā te mea he rite ēnei pūtau ki te wheketere e hanga ana i ngā pūtau toto katoa o roto i tō tātou tinana (ngā pūtau toto whero, ngā pūtau toto mā, ngā pereti toto). Ko te nuinga o ēnei pūtau take kei roto i tō tātou hinu wheua.
• Allogeneic: Ko te tikanga o tēnei kupu ko "i whiwhi mai i tētahi atu." Ko te tikanga o tēnei ka whakamahia e te maimoatanga ngā pūtau mai i tētahi kaituku hauora, hototahi, ehara i tāu ake.

Whakaarohia ko tō tātou hinu wheua he rite ki tētahi mara momona me te oneone pai. I roto i tēnei mara ka tupu ō tātou pūtau toto. Engari i roto i tētahi mate pēnei i te mate totohu, ka pirau tēnei mara, ka tupu ngā taru (ngā pūtau matepukupuku) hei utu mō ngā hua pai. Nō reira, i roto i tēnei maimoatanga, ka tangohia katoatia taua oneone pirau (te hinu wheua mate) ka whakakapia ki tētahi oneone hou, hauora, momona (ngā pūtau take a te kaituku). Kātahi ka tīmata te tipu o ngā pūtau toto hauora i roto i taua oneone hou.

He aha ngā momo āhuatanga e whakamahia ana tēnei maimoatanga?

He maha ngā wā ka whakamahia mō ngā mate e pā ana ki te toto me te pūnaha ārai mate. Anei ētahi o ngā mate matua.

Me pēhea tāu whakarite mō te maimoatanga?

Nā te mea he maimoatanga nui tēnei, ka whakahaerehia e te tīma hauora ētahi whakamātautau i mua i te wā kia tino mōhio ai koe ka taea e tō tinana te aro atu ki tēnei.

• Ngā whakamātautau toto: Ka mahia ngā mea pēnei i te tatau toto katoa (CBC) hei tirotiro i ngā taumata o ngā toto whero, ngā toto ma, me ngā pereti toto.
• Ngā whakamātautau ngākau: He echocardiogram (hei tirotiro i te pai o te mahi a te ngākau) me te electrocardiogram (EKG) hei tirotiro i te manawataki o te ngākau.
• Ka mahia ngā whakamātautau hei tirotiro i te mahi a te ate me te whatukuhu .
• Kohikohi ira wheua: Mena he mate pukupuku tōu, ka tangohia he tauira iti o te hinu wheua ka whakamatautauria hei aromatawai i te āhua o te mate me te mōrearea o te hokinga mai.

Kia oti ēnei whakamātautau katoa, ā, kia whakatauhia he pai koe, ka tīmata te wāhanga tino nui o te maimoatanga, e kiia nei ko te "pre-transplant conditioning" . Kei roto i tēnei ko te chemotherapy horopeta nui, te radiation therapy rānei ki te tinana katoa. He wā uaua pea tēnei. Engari he mea nui.

He aha te hiranga o tēnei maimoatanga i mua i te tīmatanga?

• Ka whakangaromia e ia ngā pūtau matepukupuku e toe ana i roto i tō tinana.
• Ka tangohia e ia ngā pūtau tawhito, mate i roto i tō hinu wheua, ā, ka wātea hoki he wāhi mō ngā pūtau hou ki te tupu.
• Ka ngoikore tō pūnaha ārai mate mō te wā poto. Ka mahia tēnei hei aukati i tō tinana kei whakaeke me te whakakore i ngā pūtau hou kua tukuna mai.

Me noho koe ki te hōhipera mō te kotahi, e rua rānei wiki mō tēnei maimoatanga.

He aha ngā mea ka tupu i te rā o te whakawhitinga pūtau?

He tino māmā noa iho te tukanga whakawhitinga pūtau, kāore hoki he mamae , he rite tonu ki te tuku toto.

Ka whakaurua e te tīma hauora he ngongo motuhake ki roto i tētahi uaua nui i roto i tō uma o runga. Ka kiia tēnei he Central Venous Catheter (CVC) . Ka honoa te putea kei roto ngā pūtau take hauora mai i te kaituku ki tēnei ngongo. Kātahi ka tukuna mārire ngā pūtau ki roto i tō tinana, mā roto i tō toto, me tō hinu wheua, pērā i te wai tote.

E 30 meneti ki te haora te roa o tēnei tukanga. I tēnei wā, ka noho te tīma hauora ki tō taha, ka aroturuki i tō toto toto me tō tere o te manawa. I ētahi wā, ka puta pea ngā pānga taha iti.

• Te mātao
• He uaua iti ki te manawa
• He kirika

Engari kāore ēnei i te tino kino.

He aha te mea ka tupu i muri i te maimoatanga?

Ka tīmata te wā whakaora tino nui i muri i te whakawhitinga pūtau take. Me noho koe ki te hōhipera, ki te hōhipera rānei mō ētahi atu wiki.

• Te whakahaere i te ārai mate: Ka tukuna tonutia ngā rongoā ārai mate ki a koe hei ārai i tō tinana kei whakaeke i ngā pūtau hou, me te ārai hoki i ngā pūtau hou kei whakaeke i tō tinana.
• Te whakawhiti toto: Ka roa te wā ka tīmata te mahi a ngā pūtau take hou, ka hanga hoki i ngā pūtau whero me ngā pereti toto hou. I taua wā, ka hiahia pea koe ki te whakawhiti toto.
• Te tiaki i a koe mai i ngā mate urutā: He ngoikore rawa tō pūnaha ārai mate i tēnei wā, nō reira me aro nui ki te tiaki i a koe mai i ngā mate kitakita me ngā mate huaketo.

Ko te tukanga e haere ai ngā pūtau hou ki te hinu wheua, ka noho ki reira, ka tīmata te hanga pūtau toto hou ka kiia ko te "engraftment." Ka roa pea tēnei i te 10 ki te 14 ngā rā.

Kia pēhea te roa o te wā e ora katoa ai?

He tukanga roa tēnei. E rua tau, neke atu rānei, ka roa pea kia tino ora ai. Tata ki te kotahi tau pea ka ora ai tō pūnaha ārai mate.

Mōrearea motuhake hei mōhio māu: Te Mate Graft vs. Host (GVHD)

Koinei te raruraru tino noa o te whakawhitinga allogeneic. I roto i ngā kupu māmā, ka puta mai i te wā e whakaeke ana ngā pūtau ārai mate hou mai i te kaituku (te tārai) i ngā pūtau me ngā kiko o tō tinana (te kaihautū) . He rite ki te "manuhiri e whakaeke ana i te kaihautū."

Ka taea e tēnei te ngawari, te kino rānei. Koia te take e hoatu tonutia ai ngā rongoā ārai mate. Me tino mōhio koe ki ngā tohu o tēnei mate.

Ngā tohu e tika ana kia whakamōhiotia tonutia ki tō tākuta

Ina hoki koe ki te kāinga i muri i te maimoatanga, me tino tupato koe ki ētahi tohu. Mēnā ka puta tētahi o ēnei, waea atu ki tō rōpū hauora tonu atu.

Te rerekētanga i waenga i ngā whakawhitinga "allogeneic" me ngā whakawhitinga "autologous"

Kua rongo pea koe i te whakawhitinga pūtau take autologous . Ko te rerekētanga matua i waenga i ngā mea e rua ko te pūtake o ngā pūtau.

• Allogeneic: Ka riro mai ngā pūtau i tētahi atu tangata (he kaituku).
• Autologous: Ka tangohia ngā pūtau mai i te tūroro . Ko te tikanga o tēnei ka kohia tuatahitia ngā pūtau take hauora o te tūroro, kātahi ka whakahokia atu ki a rātou i muri i te rongoā chemotherapy nui.

Ka taea e te whakawhitinga allogeneic te whakaora katoa i ētahi mate morearea. He maha ngā wā, ka mahia ēnei whakawhitinga whakaora ora e ngā kaituku kore mōhiotia kāore anō kia tūtakihia e tātou. I ētahi wā, ka noho ngā mema o te whānau hei kaituku. Ahakoa he mōrearea kei roto i tēnei maimoatanga, he tino nui hoki ngā painga. Ma tō tākuta e whakamārama enei mea katoa ki a koe, ā, ka āwhina i a koe ki te whakatau i te mea pai mōu.