Me āwangawanga rānei tātou mō te Matepukupuku o te Epithelial Ovarian?

Kua rongo kē koe i te Epithelial Ovarian Cancer? Ahakoa te ahua uaua o te ingoa, he momo mate pukupuku ovarian tēnei e kitea whānuitia ana i waenga i ngā wāhine. Me kōrero māmā noa iho, kia mārama ai koe. Nā te mea he mea nui kia mōhio koe ki ngā mea pēnei.

He aha te Matepukupuku Ovarian Epithelial?

Ki te kī māmā noa, ko te mate pukupuku ovarian epithelial te momo mate pukupuku ovarian tino noa. Ka puta tēnei mate pukupuku i roto i te uhi angiangi o waho o te ovary, e kiia nei ko te kiko epithelial. Whakaarohia he rite ki te kiriuhi angiangi e karapoti ana i te ovary.

Ehara i te mea koinā anake, engari i ētahi wā ka taea hoki e tēnei mate pukupuku te whanake i roto i te arai o ngā ngongo fallopian, i roto rānei i te peritoneum, te kiko e hipoki ana i ngā whekau o te puku. Ka whakaurua hoki e ngā tākuta te mate pukupuku ngongo fallopian me ngā mate pukupuku peritoneal tuatahi ki roto i te kāwai kotahi me te mate pukupuku ovarian epithelial nā te mea he tino ōrite ngā tohu me ngā maimoatanga mō ēnei āhuatanga.

He pēhea te noa o tēnei mate pukupuku?

Ko te mate pukupuku ovarian te tuarua o ngā mate pukupuku wahine e tino kitea ana, whai muri i te mate pukupuku uterine/endometrial. Kotahi i roto i te 78 te tūponotanga o te wahine toharite ki te pāngia e te mate pukupuku ovarian i roto i tōna oranga.

I te tau 2021 anake, neke atu i te 21,400 ngā tāngata i kitea he mate pukupuku whatukuhu. E iwa i roto i te tekau o ēnei e kīia ana he mate pukupuku whatukuhu epithelial. He tino noa tēnei mate pukupuku i waenga i ngā wāhine neke atu i te 65 tau te pakeke.

He aha ngā momo matepukupuku ovarian epithelial?

Tata ki te toru hauwhā o ngā mate pukupuku ovarian epithelial he carcinomas ovarian serous taumata teitei (HGSOC). Ko te tikanga o te "tohu teitei" he tere ake te tipu me te horapa o ēnei pūtau mate pukupuku i ngā mate pukupuku "tohu iti".

E whakapono ana ngā tohunga hauora he puhoi te tipu o tēnei momo HGSOC i te tīmatanga, engari ka roa pea ki te ono tau me te hawhe ka horapa mai i ngā ngongo fallopian ki ngā ovaries. Engari ina tae atu ki ngā ovaries, ka tere te horapa. He maha ngā wā ka pā ki te arai o te puku (peritoneum) me ētahi atu wāhanga o te tinana. Tata ki te 70% o ngā tūroro HGSOC ka kitea te mate i te wāhanga 3, 4 rānei. Ko te tikanga kua horapa te mate pukupuku ki tua atu i te pukupuku taketake, ā, kua horapa inaianei hei mate pukupuku metastatic.

Tērā atu anō ngā momo matepukupuku ovarian epithelial kāore i te tino kitea:

• Te mate pukupuku endometrioid:He nui ake te kitea o tēnei momo i roto i te hunga e pāngia ana e te endometriosis, e pā ana ki te arai o te kōpū (endometrium). He pai ake te urupare ki te chemotherapy i ētahi atu momo.
• Te mate pukupuku ovarian serous iti-rahi (LGSOC): He mate pukupuku puhoi te tipu. Ka pā ki ngā wāhine taitamariki (i waenga i te 45 me te 57 tau te pakeke). Tata ki te 10% o ngā mate pukupuku ovarian epithelial epithelial. He maha ngā wā ka horapa te mate ina kitea, ā, kāore e pai te urupare ki te chemotherapy. Ahakoa ka puhoi te tipu o ngā mate pukupuku iti-rahi, he iti ake te tūponotanga ka huri hei mate pukupuku teitei.
• Mate pukupuku mucinous: He rerekē ēnei pukupuku i ētahi atu momo, ā, he pai te urupare ki te maimoatanga. He nui te nuinga (tata ki te 8 inihi, 20 henimita rānei). He maha ngā wā ka pā ki ngā ovaries anake.
• Te mate pukupuku pūtau mārama o te ovarian (OCCC): He nui ake te mōrearea o ngā wāhine Āhia me te hunga whai endometriosis ki te pāngia e tēnei mate pukupuku. He maha ngā wā ka horapa haere te mate ina kitea. Kāore e pai te urupare ki te chemotherapy.
• Te mate pukupuku pūtau squamous tuatahi (SCC) o te ovary: Ko tēnei momo SCC ka puta mai i ngā āhuatanga pai/kore-mate pukupuku. Hei tauira, ka taea te puta mai i ngā pukupuku ovarian, te endometriosis, ngā pukupuku Brenner rānei (ngā tipu totoka, rerekē i roto i ngā ovaries). Ki te kitea wawe, ka pai te urupare ki te maimoatanga.

He aha te take o te mate pukupuku ovarian epithelial?

Ina hoki, kāore anō kia mōhiotia te tino pūtake o te nuinga o ngā mate pukupuku, tae atu ki te mate pukupuku ovarian epithelial. Heoi, e kī ana ngā rangahau hou ko te nuinga o ngā mate pukupuku ovarian ka tīmata i roto i ngā pūtau i ngā pito o ngā ngongo fallopian. Kātahi ka horapa ki ngā ovaries.

He aha ngā āhuatanga mōrearea e pā ana ki te whanaketanga o tēnei mate pukupuku?

Neke atu i te haurua o te hunga kua tāpaetia he mate pukupuku whatukuhu kei runga ake i te 65 tau te pakeke, ā, kua mutu te paheketanga, arā, kua mutu te huringa paheketanga.

Tērā pea ētahi āhuatanga ka whakanui ake i te mōrearea o te mate pukupuku whatukuhu. Ko ēnei:

• Mena kua pāngia tetahi o tō whānau e te mate pukupuku whatukuhu, te mate pukupuku ū, te mate pukupuku koroni/korokoro rānei.
• Mena kua riro mai i a koe tētahi panonitanga (whakarerekētanga) i roto i te ira BRCA.
• Mena kua riro i a koe tētahi ira e hono ana ki ngā mate pukupuku whānau, pērā i te mate Lynch.
• Mena kei te tango koe i te rongoā homoni hei whakahaere i ngā tohu o te menopause.
• Te whānautanga o te tamaiti i muri i te 35 tau te pakeke, kāore rānei i te whānau i te tamaiti tae noa ki te wā tika.
• Te momonatanga .

He aha ngā tohu o te mate pukupuku ovarian epithelial?

He raruraru tēnei mō te tini o te tangata. He iti noa ngā tohu o te mate pukupuku ovarian epithelial i ngā wāhanga tōmua. Ka kitea ngā tohu i muri i te horapa o te mate. Ina horapa ki te kiriuhi e kapi ana i ngā whekau puku (peritoneum), ka taea e te wai te kohi ki roto i te puku. Ka kiia tēnei ko te ascites.

Hei tāpiri, ka puta pea ngā tohu e whai ake nei:

• Mamae puku.
• Te uaua ki te kai, te mākona rānei i muri i te kai i te nui iti.
• Whakapairuaki me te ruaki.
• Pupuhi.
• Mamae o te hope.

Tērā anō ngā tohu kāore i te tino kitea:

• Te hiahia kia kore e taea te pupuri i te mimi, te mimi pinepine rānei (te pūkahukahu nui rawa).
• Te toto rerekē o te tara.

He mea nui: Ahakoa kei te pāngia koe e ēnei tohu, ehara i te mea he mate pukupuku tōu. Heoi, ki te mau tonu, he pai ake te toro atu ki te tākuta mō ētahi tohutohu.

Me pēhea te tautuhi i te mate pukupuku ovarian epithelial?

Engari, kāore he whakamātautau tirotiro motuhake e taea ai te kite i te mate pukupuku ovarian i ōna wāhanga tōmua. Ko te tikanga ka mahia te tirotiro mēnā he tohu kei a koe, he nui rānei te mōrearea. Tērā pea ka tirotirohia e tō tākuta te hope kia tirohia ai mēnā he puku, he pupuhi rānei.

Kātahi ka taea e koe te whakamātau toto hei tirotiro i te taumata o te pūmua e kiia nei ko te `CA-125`. Ko te tikanga o tēnei `CA-125` ko te mate pukupuku 125. Mena he teitei te taumata, me mahi anō koe i ētahi atu whakamātautau.

Ka taea e ngā whakamātautau whakaahua pēnei te āwhina i te tautuhi i te mate pukupuku ovarian:

• Whakamātautau ultrasound transvaginal.
• Whakamātautau matawai CT.
• Whakamātautau MRI (MRI).
• Matawai i te tomotanga tukunga Positron (PET).
• Ngā hihi-X o te uma (kia kitea ai mēnā kua horapa te mate pukupuku ki ngā pukahukahu).

I ētahi wā, ka taea te mahi i tētahi tikanga e kiia nei ko te laparoscopy. He rite tēnei ki te pokanga, engari kāore e mahia he tapahi nui. Mā tēnei ka taea e te tākuta te tirotiro i ō whekau whakaputa uri. Ka tangohia pea e rātou he tauira kiko (biopsy) mai i tētahi puku hei tirotiro mēnā he pūtau matepukupuku kei reira. Ko tēnei biopsy anake te huarahi hei mōhio māu mēnā he matepukupuku ovarian tōu.

He aha ngā wāhanga o te mate pukupuku ovarian epithelial?

Mā te mōhio ki te taumata o te mate pukupuku ka āwhina i ngā tākuta ki te mārama ki te ahunga whakamua o te mate pukupuku. He mea nui anō hoki hei whakatau mēnā kua horapa te mate pukupuku, hei whakatau hoki i te maimoatanga. Ka whakatauhia te taumata o te mate pukupuku e ngā whakamātautau kotahi e whakamahia ana hei tātaritanga i te mate pukupuku.

E whā ngā wāhanga matua o te mate pukupuku whatukuhu. He wāhanga iti ētahi. Ka teitei ake te tau wāhanga, ka nui haere te whanaketanga o te mate pukupuku.

• Wāhanga 1: Kei roto i te ovary kotahi, i te ngongo fallopian kotahi rānei te mate pukupuku.
• Wāhanga 2: Kua horapa te mate pukupuku ki te kōpū, ki te arai rānei o te kōhao puku (kōhao peritoneal).
• Wāhanga 3: Kua horapa te mate pukupuku ki ētahi atu whekau i waho o te hope, ki ngā kōpū lymph, ki ngā mea e rua rānei.
• Wāhanga 4: Kei roto ngā pūtau matepukupuku i te wai e karapoti ana i ngā pukahukahu, i ngā kōpū lymph i te rohe o te hope, i ētahi atu okana, i ētahi atu wāhanga rānei o te tinana.

Ka taea te rongoā i te mate pukupuku o te ovarian epithelial?

Ka whakahaerehia e ngā taote pokanga he pokanga tango i te nui o te mate pukupuku e taea ana. Whai muri i tēnei ka whakahaerehia he rongoā matepukupuku. Ahakoa ka ora te nuinga o te tangata i te tīmatanga, ka taea e te mate te hoki mai anō i roto i te tini o te tangata i muri mai.

Tērā pea ka whakatau ngā tūroro wā tōmua ki te tango i te ovary me te ngongo fallopian mate anake.

Mō te hunga mate pukupuku kua pāngia e te mate pukupuku kua horapa haere, ka mahia he pokanga tango i te puranga hei tango i ngā whekau e whai ake nei:

• Te tango i ngā ngongo fallopian me ngā ovaries e rua (bilateral salpingo-oophorectomy).
• Te tango i te kōpū (hysterectomy).
• Te tango i te kiko ngako (omentum) e hipoki ana i te puku (omentectomy).
• Te tango i ngā kōpū lymph e karapoti ana.
• Te tango i ētahi atu wāhanga mate (pērā i te whekau iti, te whekau nui, te whēkau rānei).

He aha ētahi atu maimoatanga?

I runga i te momo mate pukupuku, ka tukuna pea ki a koe tētahi, ētahi rānei o ēnei maimoatanga i muri i te pokanga:

• Te rongoā matū: Hei patu i ngā pūtau matepukupuku. Ka whakamahia ngā rongoā pēnei i ngā matū konupūmā (carboplatin) me te paclitaxel (Taxol®) me te docetaxel (Taxotere®) rānei.
• Te rongoā matepukupuku i roto i te puku: Hei rongoā i te matepukupuku ovarian wāhanga 3, ka werohia tika ngā rongoā cisplatin me te paclitaxel ki roto i te kōhao puku mā roto i tētahi catheter (he ngongo angiangi, tuwhera) kua werohia ki te pokanga.
• Ngā rongoā kua arotahihia: Ka aukatihia e ngā rongoā pēnei i a Bevacizumab (Avastin®) te tipu me te whakarea o ngā pūtau matepukupuku.
• Whakaora irahiko: Ka whakamahi i ngā hihi-X kaha-teitei hei whakangaro i ngā pūtau matepukupuku.

Ka taea te ārai i te mate pukupuku o te ovarian epithelial?

E whakaatu ana ngā rangahau ka taea e ngā wāhine e tango ana i ngā pire ārai whānau homoni mō ngā tau e rima, neke atu rānei, te whakaiti i tō rātou tūponotanga ki te pāngia e te mate pukupuku whatukuhu mā te haurua pea.

Ka taea hoki e ētahi pokanga te whakaiti i te mōrearea o te mate pukupuku. Ko te pokanga hei ārai i te mate pukupuku ka kiia ko te pokanga ārai mate pukupuku. Ko tēnei ko te tango i ngā ngongo fallopian me ngā ovaries, me te kōpū, me te kore rānei. Ko te tikanga ka whakaarohia tēnei mō ngā wāhine he nui te mōrearea nā te hītori whānau (pērā i te hunga he whakarerekētanga BRCA, he Lynch syndrome rānei). Heoi, ka tohutohu ngā tākuta me mahi noa ēnei tikanga mēnā e tika ana kia rongoatia. Nā te mea ka taea e te tango i ngā ovaries te whakapōrearea wawe i te menopause, ka pā kino pea ki te tinana.

Kāore ēnei pokanga e whakakore katoa i te mōrearea o te mate pukupuku. Tērā pea he mate pukupuku kei ētahi tāngata kāore i kitea i te wā o te pokanga. Ahakoa kua tangohia ngā ngongo me ngā ovaries o te kōpū, ka taea tonu e te hunga whai whakarerekētanga ira BRCA te whakawhanake i te mate pukupuku peritoneal tuatahi. Pātai atu ki tō tākuta mō te whakamātautau BRCA kia kitea ai mēnā kei a koe te ira BRCA.

He aha te tirohanga mō te hunga e pāngia ana e te mate pukupuku ovarian epithelial?

Neke atu i te 13,000 ngā tāngata e mate ana i te mate pukupuku whatukuhu i ia tau. Koinei te tuarima o ngā take matua o te mate pukupuku i waenga i ngā wāhine. Heoi anō, kei te wātea te tumanako mō ngā maimoatanga hou kei roto i ngā whakamātautau haumanu. Kei te mahi hoki ngā kairangahau ki te kite i te mate i te wā tōmua.

Mena ka kitea te mate pukupuku ovarian i mua i te horapa, neke atu i te 90% te ōrau oranga mō ngā tau e rima. Heoi, ina horapa te mate pukupuku (kua horapa), ka heke tēnei ōrau ki te 30%.

He maha ngā āhuatanga e pā ana ki te matapae o te mate pukupuku:

• Te whānuitanga o te horapa o te mate pukupuku.
• Te angitu o te maimoatanga.
• Te wāhi, te rahi, me te maha o ngā pukupuku matepukupuku (te wāhanga o te matepukupuku).

Āhea koe me toro atu ki te tākuta?

Mena kei a koe tētahi o ēnei tohu, me toro atu ki te tākuta tonu:

• Ngā huringa o te auau, te hiahia rānei ki te mimi.
• Te ngaronga o te hiahia kai, te mākona rānei i muri i te kai i te nui iti.
• Te mamae tonu i roto i te puku, i te hope rānei, kāore he take.

He aha ngā pātai me pātai atu koe ki tō tākuta?

Ka taea e koe te pātai atu ki te tākuta i ngā pātai penei:

• Me whiwhi ahau i tētahi whakamātautau BRCA?
• He aha te momo mate pukupuku ovarian epithelial kei a au?
• He aha te maimoatanga pai rawa atu mōku?
• He aha ngā pānga taha o ngā maimoatanga?
• Kei te tūpono ahau ki te mate pukupuku horapa? Me pēhea taku whakaiti i taua tūponotanga?
• Me āwangawanga ahau mō ngā raruraru?

He aha te momo matepukupuku whatukuhu tino kaha rawa atu?

He momo mate pukupuku ovarian tino kaha te mate pukupuku ovarian serous teitei (HGSOC). Ahakoa i te tīmatanga ka puhoi te tipu o tēnei mate pukupuku i roto i ngā ngongo fallopian, ka tere te horapa ina tae ki ngā ovaries. Engari, he maha ngā tāngata whai HGSOC kua pāngia e te mate pukupuku ovarian kua horapa/kua horapa ina kitea.

Ka taea te whai i ngā pukupuku ovarian epithelial kore-matepukupuku (pai)?

Āe. Ina hoki, ko te nuinga o ngā pukupuku ovarian epithelial ehara i te matepukupuku. Ko ētahi pukupuku e kiia ana he pukupuku borderline, he pukupuku atypical proliferating rānei. I mua i huaina ēnei he pukupuku low malignant potential.

I roto i ngā pukupuku rohe, ka tipu ngā pūtau rerekē ki roto i te kiko epithelial engari kāore e uru ki te kiko tautoko o te ovary (stroma). I te nuinga o te wā ka kitea ēnei pūtau i roto i te ovary tonu, ā, he onge te noho hei matepukupuku. Mēnā ka puta te matepukupuku, e toru o te whā he wāhanga 1 (e noho ana ki te ovary, ā, he ngāwari ki te rongoā). I te nuinga o te wā ka pāngia te hunga rangatahi e ēnei pukupuku.

Karere Tangohia ki te Kāinga

Ko te mate pukupuku ovarian epithelial te momo mate pukupuku ovarian tino noa. Kei roto hoki i tēnei mate te mate pukupuku o te ngongo fallopian me te mate pukupuku peritoneal tuatahi. He iti noa iho ngā tohu o te mate pukupuku ovarian i ōna wāhanga tōmua. He maha ngā wā kua tino pāngia te mate e te mate kāore e taea te kite i te wā e tautuhia ai. He pono rawa tēnei mō te momo mate pukupuku epithelial tino noa, e kiia nei ko te `HGSOC`.

Mena he nui te tūponotanga o te mate pukupuku whatukuhu (pēnei i te hītori whānau), he mea nui kia pātai atu koe ki tō tākuta mēnā he tika ngā mahi ārai mate mōu. Tiakina tō tinana i ngā wā katoa. Kaua e warewarehia ngā tohu rerekē. Rapua he tohutohu hauora.

` Matepukupuku ovarian, matepukupuku epithelial, hauora o ngā wāhine, ngā tohumate o te matepukupuku, te maimoatanga o te matepukupuku, te ira BRCA, te rongoā wahine