He nui te cholesterol? Me kōrero tāua mō ēnei statin?

He tokomaha o tātou e raru ana ki te cholesterol teitei. He mea noa te mataku me te manukanuka ina whiwhi koe i ngā hua o tō whakamātautau toto, ā, ka kite koe kei runga ake i te toru mati te taumata o tō LDL. Nō reira, kua kī atu tō tākuta kia tīmata koe ki te tango i tētahi rongoā e kiia nei ko ngā statin hei whakahaere i tō cholesterol? Tērā pea kei te tango kē koe i tēnei rongoā. Nō reira, he maha pea āu pātai mō tēnei rongoā, tōna whai huatanga, me ōna painga me ōna huakore. Me whakamārama tātou i ō pātai katoa mō tēnei rongoā i tēnei rā.

Hei whakarāpopototanga, he aha ēnei statin?

Ko ngā statin he momo rongoā ka taea anake te tango me te whakahaunga a te tākuta. Ko tā rātou mahi matua he whakataurite i ō taumata cholesterol. Ina koa, ka taea e ētahi statin te whakaiti i tō cholesterol LDL (Low-Density Lipoprotein), e mōhiotia ana ko te cholesterol "kino", mā te 50% neke atu rānei.

He take te kī a ngā tākuta he "kino" te cholesterol LDL. Whakaarohia ngā uaua e kawe ana i te toto puta noa i tō tinana he rite ki ngā paipa wai. Ko tā tēnei cholesterol LDL e mahi ana ko te whakatakoto i a ia anō ki runga i ngā pakitara o aua paipa wai pērā i te pūkohu. I roto i te wā, ka hanga ēnei putunga (e kiia ana e mātou he paraka) ka whakaiti i te wāhi i roto i ō uaua toto. Mā tēnei ka kaha ake te mahi a te ngākau ki te pupuhi toto, ā, ka aukati hoki i te rere o te toto.

Ehara i te mea ka whakaiti noa ngā statin i te LDL. Ka whakaitihia hoki e rātou tētahi atu momo ngako i roto i ō toto e kiia nei ko ngā triglycerides. Ka āwhina hoki i tō ate ki te whakakore i te cholesterol kāore e hiahiatia. I ētahi wā ka taea hoki e ēnei rongoā te whakanui ake i ō taumata o te HDL (High-Density Lipoprotein), e mōhiotia ana ko te cholesterol "pai" . He "pai" te HDL nā te mea ka kohia e ia te cholesterol kāore e hiahiatia mai i te tinana katoa ka tukuna ki te ate. Kātahi ka tangohia e te ate mai i te tinana.

Kei roto i te ahua o ngā papa, ngā kāpū rānei ēnei rongoā. Ka tangohia kotahi i te rā. Ka taea te tango me te kai, me te kore kai rānei. Ko te mea nui ko te tango i aua rongoā i te wā kotahi i ia rā. Mā te tapanga kei runga i tō pounamu rongoā koe e whakaatu ko tēhea te wā o te rā hei tango. I te nuinga o te wā, ka tangohia ngā statin poto-mahi i te pō nā te mea he nui ake te cholesterol e whakaputaina ana e ō tātou tinana i te pō i a tātou e moe ana. Heoi, kāore ngā statin roa-mahi i te tino whai hua i tētahi wā o te rā.

Āe, kia titiro tātou me pēhea te mahi a tēnei rongoā i roto i te tinana.

He tino māmā noa iho tēnei ki te mārama. Whakaarohia ko tō ate te wheketere matua e hanga ana i te cholesterol. 75% o te cholesterol e hiahiatia ana e tō tātou tinana ka hangaia e tēnei ate. Ko te toenga ka ahu mai i te kai e kainga ana e tātou.

Nō reira, kia mahi ai tēnei wheketere hanga cholesterol, me whai kaimahi nui. He whākōkī tēnā e kiia nei ko te HMG-CoA reductase. He rite ki te hiahia ki tētahi mīhini mohio ki te hanga waka.

He tino mārie te mahi a ngā statin. He rite ki te kaitiaki haumaru i te kūaha o te wheketere. Ka aukatihia e ngā statin te whākōkī HMG-CoA reductase kei uru ki te wheketere. Arā, ka āraia e rātou. Ka ahatia i muri mai? Nā te mea kua ngaro te "kaimahi" matua e hanga ana i te cholesterol, ka tino heke te hanga cholesterol o te ate. Koinei te huarahi e whakahaere ai ngā statin i ngā taumata cholesterol i roto i ō toto.

He aha tātou i hiahia ai ki ēnei statin?

Ko te take matua he whakaiti i te mōrearea o te mate ngakau me te whiu.

He mea nui te cholesterol mō ō tātou tinana ki te hanga huaora D, ngā homoni, me ngā waikawa hei āwhina i te nakunaku kai. Engari ko te raruraru, he nui rawa te cholesterol e kohia ana i roto i te toto.

E ai ki taku kōrero i mua ake nei, ka tīmata te hanga o tēnei cholesterol tāpiri ki roto i ngā oko toto. Ka kiia tēnei he atherosclerosis. I roto i te wā, ka whakawhāitihia ngā oko toto e ēnei putunga (pēra). Kātahi ka iti ake te wāhi e rere ai te toto. He rite ki te waka i runga i te huarahi pukumahi.

Ka kino rawa atu pea te āhua. I ētahi wā, ka kore e pumau, ka pakaru ohorere ngā putunga cholesterol kua hangai ki roto i aua oko toto. Mēnā ka puta he toto totoka ki reira, ka taea e ia te aukati katoa i te oko toto. Mēnā ka puta tēnei aukati i roto i te uaua toto e tuku toto ana ki te ngākau, ka puta he mate ngākau . Mēnā ka puta i roto i te uaua toto e tuku toto ana ki te roro, ka puta he whiu . Ka whakaitihia e ngā statins te cholesterol, ā, ka tiaki i a tātou mai i ēnei mate kino.

He aha ngā momo statin kei te mākete?

He maha ngā momo statin. Mā tō tākuta e whakatau te momo me te horopeta e pai ana mōu i runga i tō āhua.

I ētahi wā, ka hoatu he rongoā statin i roto i te pire whakakotahi me tētahi atu rongoā.

• Simvastatin me te ezetimibe, te niacin rānei
• Atorvastatin me te ezetimibe, te amlodipine rānei
• Lovastatin me te niacin

Ko wai me tango i ngā statins?

He pātai tino nui tēnei. Ehara ngā statin i te rongoā kotahi mō ngā tāngata katoa. Ka tohua tēnei rongoā e te tākuta i runga i tō tūponotanga whānui ki te pāngia e te mate o te ngākau me ngā oko toto.

Ko te tikanga, ka tūtohuhia ngā statins mō:

• Mō te hunga kāore e taea te whakahaere i ō rātou taumata cholesterol mā te kai me te whakakori tinana .
• Mō ētahi tāngata, nā ngā take ira (ngā ira tuku iho), arā, he nui ake te cholesterol e whakaputaina ana e te tinana i te mea e tika ana. Mō ērā tāngata.
• Mō te hunga he take mōrearea tō rātou ki te mate ngakau, pērā i te mate huka, te toto toto tiketike, me te kai tupeka.

I te whakatau mēnā me whakamahi koe i ngā statin, ka whakaarohia e tō tākuta ngā āhuatanga maha, tae atu ki tō tau, tō ira tangata, me tō hītori whānau. Tērā pea ka tohua ngā statin mō ngā pakeke, ā, i ētahi wā, mō ngā tamariki nohinohi.

Anei ētahi āhuatanga e taunaki ana ngā tākuta i ngā statin:

• Mō te hunga he tino tiketike ō rātou taumata cholesterol kino (LDL), neke atu i te 190 mg/dL, ā, kāore e taea te whakahaere mā te whakarerekē i te momo noho.
• Ko te hunga i waenga i te 40-75 tau te pakeke he mate huka, ā, he nui ake i te 70 mg/dL ngā taumata LDL.
• Mō te hunga kua pāngia e te mate manawa, te whiu, te mate uaua ā-roto rānei (PAD) i mua.
• Mō te hunga 40-75 tau te pakeke, he nui ake ngā taumata LDL i te 70 mg/dL, ā, he nui hoki te mōrearea ki te whakawhanake i ngā mate manawa.

He pānga taha rānei ō ngā statin?

Pērā i ngā rongoā katoa, ka pāngia pea te nuinga o ngā tāngata e ngā pānga taha o te statin. Engari ko te mea nui, kāore te nuinga o te tangata e pāngia e ngā pānga taha. Ahakoa ka pāngia, he iti noa iho te nuinga.

Heoi, he mea tino nui kia mōhio koe ki tēnei. Mēnā ka pāngia koe e ētahi pānga taha, me whakamōhio atu koe ki tō tākuta. Kātahi ka taea e ia te whakarerekē i tō horopeta, te whakawhiti rānei i a koe ki tētahi atu statin.

Ngā pātai e pā ana ki ngā statin

Ka aha mēnā ka mutu ohorere te tango i ngā statin?

He tino morearea tēnei. Ki te mutu te tango i ngā statin me te kore tohutohu a tō tākuta, ka tīmata anō te pikinga o ō taumata cholesterol. Ko te tikanga ka piki anō tō tupono ki te mate manawa me te whiu. He rite tēnei ki te tango i tētahi maru i te matau i te ua. Ka ngaro te tiaki e whakaratohia ana e te rongoā. Nō reira , kaua e mutu te tango i te rongoā mō tētahi take me te kore pātai ki tō tākuta.

Ka hua ake te taumaha i ngā statins?

Kua kitea e ētahi rangahau ka taea e ngā statin te whakanui ake i te taumaha. Ko tētahi atu mea, ina tīmata ētahi tāngata ki te tango i te rongoā, nā te mea he pai ō rātou taumata cholesterol, ka whakaaro rātou, "Kua pai ahau ināianei," ā, ka wareware ki te whakahaere i ā rātou kai me te whakakori tinana. Ahakoa i taua wā, ka taea tonu e rātou te whakanui ake i te taumaha. Kia mahara, ahakoa ka tango koe i ngā statin, he mea nui kia mau tonu te oranga hauora.

Āhea ahau me toro atu ki te tākuta i ahau e tango ana i tēnei rongoā?

Mena ka pāngia koe e tētahi o ngā tohu e whai ake nei i a koe e tango ana i ngā statins, me kōrero tonu atu ki tō tākuta:

• Te mamae uaua, te mamae hononga rānei e kore e taea te whakamanawanui
• ngoikore
• Kirika
• Te kōwhai o ngā kanohi, o te kiri rānei (Jaundice)
• Mimi pouri

He tangata kei reira kāore e tika ana kia tango i ngā statins?

Āe. Kāore e pai ngā Statin mō ētahi tāngata.

• Mō ngā wāhine hapu
• Mō ngā whaea whāngai
• Mō te hunga whai mate ate kino

Mena he mate huka tōu, kōrero ki tō tākuta. Mō te tangata kua tūpono kē ki te pāngia e te mate huka, ka paku whakanui ake pea ngā statin i taua mōrearea. Heoi, nā te mea he nui ake te mōrearea o te hunga mate huka ki te pāngia e te mate manawa, he nui ake ngā painga o ngā statin i te mōrearea iti. Ko tō tākuta te tangata pai rawa atu hei whakatau i tēnei.