He mea noa kia mataku te tangata ina rongo i te kupu matepukupuku ū. Engari ko te mea nui me mōhio tātou, ehara i te mea he rite katoa ngā matepukupuku ū. He rerekē ngā momo. I tēnei rā ka kōrero tātou mō tētahi momo he onge ake, ā, me aro nui ki te wā e rongoatia ana. Ka karangatia tēnei ko te 'Triple-Negative Breast Cancer' (TNBC te poto). Tērā pea he ahua uaua ki a koe te rongo i tēnei ingoa, engari kaua e mataku. Ka kōrerohia tēnei e tātou me te tino māmā, i roto i te huarahi e mārama ai koe.
He aha i huaina ai tēnei ko 'Toru-Kino'?
Āe, me tīmata tātou ki te tikanga o tēnei ingoa. Hei mārama ki tēnei, me mārama tātou ki te mahi a ngā pūtau matepukupuku ū noa.
Whakaarohia he rite ngā pūtau o tō tātou tinana ki ngā tatau. He raka kei aua tatau hei pupuri i ngā kī. I roto i te rongoā, ka kiia ēnei kōhao kī he 'kaiwhakawhiwhi'. Ina tae mai ngā kī e ōrite ana ki ēnei kaiwhakawhiwhi, ka hono atu, ka whiwhi aua pūtau i ētahi karere.
E toru ngā momo kaiwhakawhiwhi he mea nui ki te mate pukupuku o te ū.
1. Ngā Kaiwhakawhiwhi Estrogen (ER): E pā ana ēnei ki te homoni wahine o te estrogen.
2. Ngā Kaiwhakawhiwhi Progesterone (PR): E hono ana ēnei ki tētahi atu homoni wahine e kiia nei ko te progesterone.
3. Ngā Kaiwhakawhiwhi HER2: He kaiwhakawhiwhi tēnei e herea ana ki tētahi pūmua e kiia nei ko te HER2. Mā tēnei pūmua e whakahaere te tipu o ngā pūtau o te ū.
I roto i ngā momo mate pukupuku ū maha, ka nui rawa te whakaputanga o tētahi, e rua, e toru rānei o ēnei kaiwhakawhiwhi. Ko te tikanga o tēnei, ka āwhina ēnei homoni me ngā pūmua i te tipu o ngā pūtau mate pukupuku. He rite ki te tāpiri wahie ki te ahi. Nō reira, ina rongoatia ēnei mate pukupuku e ngā tākuta, ka aro atu rātou ki ēnei kaiwhakawhiwhi ka hoatu ki a rātou he rongoā hei aukati i a rātou (he rongoā arotau). Ka kati ēnei rongoā i aua 'kōhao kī'. Kātahi ka kore ngā pūtau mate pukupuku e whiwhi i ngā karere e hiahiatia ana e rātou hei tipu.
Ki te kī ngāwari, ko te tikanga o te 'toru-kino' kāore i roto i ēnei pūtau matepukupuku ngā kaiwhakawhiwhi e toru kua whakahuatia ake nei (estrogen, progesterone, me te HER2) . Ko te tikanga o te 'kino' ko te 'kāore'. He 'toru-kino' nā te mea kāore i roto i a ia ngā kaiwhakawhiwhi e toru.
Kua mārama pea koe ki te wāhi e takoto ana te raruraru? Kāore ngā rongoā e aro ana ki ngā kaiwhakawhiwhi e mahi mō tēnei momo mate pukupuku. Nā te mea kāore he kaiwhakawhiwhi hei aro atu. Koinei te wero matua o te mate pukupuku TNBC. Engari ehara i te mea kāore e taea te rongoā. He maha atu anō ngā maimoatanga whai hua mō tēnei, ā, ka kōrerohia e tātou i muri mai.
He aha ngā tohu o tēnei mate pukupuku?
He tino rite ngā tohu o te matepukupuku ū triple-negative ki ērā o ētahi atu matepukupuku ū. Mēnā ka kite koe i tētahi mea rerekē i roto i ō ū, he mea nui kia aro atu koe.
Ki te mea kei a koe tētahi, ētahi rānei o ngā tohu e whai ake nei, kaua e mataku, me toro atu ki te tākuta i te wā e taea ai. Ehara i te mea ko te mate pukupuku te tohu mēnā kei a koe ēnei tohu, engari he mea whakaaro nui kia tirohia koe.
| Tohu | He whakamārama māmā |
|---|---|
| He puku hou, he matotoru rānei i roto i te ū | He mea pērā i te puku kāore anō kia kitea i mua, e mau ana i te ringa. |
| Mamae o te ū, o te uma rānei | Mamae auau, kāore i te mārama. |
| Ngā huringa kiri o te ū | He pīataata, he whero, he matotoru, he maroke rānei te kiri, he rite ki te kiri karaka. |
| Hurihanga o te uma | Ka totohu ki roto te uma o te uma i mua he rite tonu. |
| Puta mai i te uma | Te turuturu o te toto, o tētahi atu wai rānei mai i te uma i te mea ehara koe i te whaea whāngai u. |
| Pupuhi o te ū | Te pupuhi o te ū, i te katoa, i te wāhanga rānei. |
| Ngā puku i roto i te kēkē, i te taha rānei o te wheua kara | Ngā puku i puta mai i te pupuhi o ngā kōpū lymph. |
Kia maumahara, ka taea e te mammogram auau te kite i te mate pukupuku i mua i te putanga mai o ngā tohu. Nō reira, he mea tino nui kia tirotirohia i te wā tika mō te pakeketanga.
He aha ngā take me ngā āhuatanga mōrearea e pā ana ki te whanaketanga o tēnei mate pukupuku?
Kāore anō kia kitea e ngā kairangahau tētahi tino take mō tēnei mate pukupuku, engari kua kitea e rātou he hononga kaha kei waenganui i tēnei mate me ngā ira.
Ina koa, he hononga kaha kei waenganui i ngā whakarerekētanga ira o ngā ira BRCA1 me BRCA2 me TNBC. I te nuinga o te wā, ko ēnei ira BRCA te kawenga mō te whakahaere i te tipu o te mate pukupuku i roto i ō tātou tinana. Pērā i te pūnaha parai o te motuka. Ina he hapa, he whakarerekētanga rānei i roto i ēnei ira, ka ngaro te kaha ki te whakahaere i te mate pukupuku. Ka taea e tātou te tuku iho i ēnei whakarerekētanga ira mai i ō tātou mātua.
Haunga tēnei, he maha atu anō ngā āhuatanga ka piki ake ai te mōrearea ki te whakawhanake i te mate pukupuku TNBC.
| Tauwehenga mōrearea | Whakaahuatanga |
|---|---|
| Tau | He mea tino noa tēnei i roto i ngā wāhine taitamariki kei raro iho i te 40 tau te pakeke. (Engari ka taea te whanake i ngā tau katoa.) |
| Ngā whakarerekētanga ira BRCA | He nui rawa te mōrearea mēnā ka tukuna iho he whakarerekētanga ira BRCA1. |
| Iwi/iwi taketake | E ai ki ngā rangahau i mahia puta noa i te ao, he nui ake te kitea o tēnei mate pukupuku i waenga i ngā wāhine o te uri Āwherika, o te uri Hispanika rānei. |
Me pēhea te tātaritanga a te tākuta i tēnei?
Ina haere koe ki te tākuta mō te puku o te ū, ka tirohia tuatahitia e ia ō ū. Kātahi ka pātai atu rātou ki a koe mō ō tohumate. Hei tāpiri, ka whakaritea e rātou ētahi whakamātautau hei whakaū i te mate.
- Mammogram: He whakamātautau hihi-X o te ū.
- Te Whakamātautau Umu: He tikanga e whakamahi ana i ngā ngaru oro hei tango whakaahua o ngā kiko i roto i te ū.
- MRI o te ū: He tikanga e whakamahi ana i te papa aukume me ngā ngaru reo irirangi hei whakaputa whakaahua mārama ake, taipitopito ake hoki.
Mena he tohu mate pukupuku ēnei karapa, ko te whakamātautau nui e whai ake nei ko te koiora . Ko te tango i tētahi wahi kiko iti rawa mai i te puku whakapae mā te whakamahi i tētahi ngira iti, kātahi ka tirotirohia i raro i te karu hiko.
Ko te koiora anake te huarahi hei whakaū 100% mēnā he mate pukupuku tēnei, kāore rānei. Waihoki, ko te huarahi anake hei mōhio mārika mēnā he TNBC tēnei, ko te tirotiro i tēnei wahi kiko, me te kite mēnā kei roto ngā kaiwhakawhiwhi e toru i kōrerohia e tātou (ER, PR, HER2).
Hei tāpiritanga, ka tukuna pea koe e tō tākuta mō te whakamātautau ira hei tirotiro i ngā whakarerekētanga ira, pērā i te BRCA. Ka whakamahia ēnei mōhiohio katoa hei whakatau i te wāhanga o tō matepukupuku, me te whakawhanake i te mahere maimoatanga tino tika māu.
He aha ngā maimoatanga mō tēnei?
Ahakoa he uaua te rongoā i te mate pukupuku TNBC, he maha ngā maimoatanga tino whai hua e wātea ana ināianei. Ka tūtohu tō tākuta mate pukupuku i te mahere maimoatanga pai rawa atu i runga i tō āhua.
Ko te maimoatanga matua ko te tango i te pukupuku matepukupuku mā te pokanga. Hei tāpiri, ka taea te whakamahi ngātahi i tētahi, i ētahi rānei o ngā maimoatanga e whai ake nei.
- Te rongoā matū: Koinei tētahi o ngā maimoatanga matua me te tino whai hua mō te TNBC. Ka hoatu te rongoā matū i mua i te pokanga hei whakaiti i te pukupuku (te rongoā matū neoadjuvant) me muri i te pokanga hei patu i ngā pūtau matepukupuku e toe ana, hei ārai hoki i te hokinga mai o te mate (te rongoā matū adjuvant).
- Whakaora Irahiko: I muri i te pokanga, ka tukuna ngā hihi kaha-nui ki te wāhi i puta ai te mate pukupuku hei whakangaro i ngā pūtau mate pukupuku e toe ana.
- Te Whakaora Ārai Mate: He maimoatanga hou tēnei. Mā te whakaoho i te pūnaha ārai mate o tō tātou tinana kia kite me te whakaeke i ngā pūtau matepukupuku. Mō ētahi tūroro TNBC, ka taea te hoatu i tēnei maimoatanga me te chemotherapy hei whakatutuki i ngā hua tino pai.
- Te Whakaora Whaiaro: Mō ngā tūroro TNBC me ngā whakarerekētanga ira BRCA, ka whakamahia ngā rongoā motuhake pēnei i ngā aukati PARP . Ka mahi ēnei mā te whakararuraru i te kaha o ngā pūtau matepukupuku ki te whakatika i a rātou anō.
He maha ngā whakamātautau haumanu kei te haere tonu puta noa i te ao mō te TNBC. Kei te kitea tonutia ngā rongoā hou me ngā maimoatanga hou. Nō reira, he pai te tumanako mō te heke mai o tēnei mate.
Ngā mea hei whakaaroaro i muri i te maimoatanga
I muri i te pokanga, i ētahi atu maimoatanga rānei, ka puta pea ngā raruraru i ētahi wā. Hei tauira, ka pangia pea te patunga pokanga, ka puta rānei he toto totoka. Nō reira, ki te pāngia koe e tētahi o ngā tohu e whai ake nei, whakapā atu ki tō tākuta tonu.
| Āhea te rapu tohutohu hauora tonu | |
|---|---|
| Ngā tohu o te mate urutā |
|
| Ngā tohu o te toto totoka | He pupuhi mamae o te waewae, he uaua ki te manawa. |
| Ngā pānga taha nui rawa | Mena he kino rawa ngā pānga taha o te maimoatanga (hei tauira, te ruaki, te korere). |
Ngā mea ka taea e koe te mahi hei pupuri i te hauora i te wā e maimoatanga ana
He tino taumaha te maimoatanga matepukupuku, ā-tinana, ā-hinengaro hoki. Tērā ētahi mea hei āwhina i a koe kia marino ake i tēnei wā.
- Korikori tinana māmā: Mā ngā mahi māmā pēnei i te hikoi me te yoga ka āwhina i te whakaiti i te ahotea, ā, ka nui ake hoki te kaha o tō tinana.
- Kai pai: Kai i ngā kai totika e whai kiko ana i ngā pūmua kikokore (ika, heihei), ngā hua rākau, ngā huawhenua, ngā pīni, me ngā witi katoa (raihi parauri, ōti). Inuhia he nui te wai.
- Te pupuri i te taumaha hauora: Kua whakaatuhia e ngā rangahau he tautoko pai te pupuri i te taumaha hauora e tika ana mōu mō te maimoatanga.
- Tautoko hinengaro:Kōrero ki tō whānau me ō hoa tata mō ō kare ā-roto, ō mataku, me ō manukanuka. Mēnā e tika ana, rapua he āwhina a tētahi kaitohutohu hauora hinengaro.
Mena he kino ngā pānga taha o te maimoatanga, kaua e whakamā ki te kōrero ki tō tīma hauora mō tēnei mea. E whakapau kaha ana rātou ki te tautoko i a koe i tēnei wā uaua.
Karere Tangohia ki te Kāinga
- Ko te mate pukupuku ū toru-kino (TNBC) he momo mate pukupuku ū motuhake kāore i a ia ngā kaiwhakawhiwhi e toru: te estrogen, te progesterone, me te HER2.
- Nō reira, kāore e whai hua ngā rongoā homoni tuku iho me ngā rongoā e arotahi ana ki te HER2 mō tēnei.
- Ki te kite koe i ētahi panoni rerekē i roto i tō ū (he puku, he mamae, he panoni kiri), kaua e mataku, engari me toro atu ki te tākuta tonu. Ko te tere o te kitenga, ko te angitu ake o te maimoatanga.
- He maha ngā maimoatanga whai hua mō tēnei, tae atu ki te chemotherapy, te pokanga, te radiation therapy, me ngā maimoatanga hou pērā i te immunotherapy.
- Ahakoa he mate uaua tēnei, kei te kitea tonutia ngā maimoatanga hou i te whanaketanga o te rongoā hou. Nō reira kaua e mutu te tumanako.
- Whakawhirinaki ki tō tīma hauora, whakautua ā rātou pātai me te pono, me pātai atu ki a rātou mō ō āwangawanga. Kāore koe i te mokemoke i tēnei haerenga.
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